{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T06:04:42Z","timestamp":1793253882409,"version":"4.5.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2006,6,20]],"date-time":"2006-06-20T00:00:00Z","timestamp":1150761600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1007\/s00403-006-0668-y","type":"journal-article","created":{"date-parts":[[2006,6,19]],"date-time":"2006-06-19T11:52:00Z","timestamp":1150717920000},"page":"131-134","source":"Crossref","is-referenced-by-count":26,"title":["Induction of cellular immunity against hair follicle melanocyte causes alopecia"],"prefix":"10.1007","volume":"298","author":[{"given":"Hiroshi","family":"Nagai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuntaro","family":"Oniki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Horikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikako","family":"Nishigori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,6,20]]},"reference":[{"key":"668_CR1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/00007611-199504000-00024","volume":"88","author":"M Cho","year":"1995","unstructured":"Cho M, Cohen PR, Duvic M (1995) Vitiligo and alopecia areata in patients with human immunodeficiency virus infection. South Med J 88:489\u2013491","journal-title":"South Med J"},{"key":"668_CR2","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1046\/j.1365-2133.2000.03464.x","volume":"142","author":"T Christoph","year":"2000","unstructured":"Christoph T, Muller-Rover S, Audring H, Tobin DJ, Hermes B, Cotsarelis G, Ruckert R, Paus R (2000) The human hair follicle immune system cellular composition and immune privilege. Br J Dermatol 142:862\u2013873","journal-title":"Br J Dermatol"},{"key":"668_CR3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1172\/JCI551","volume":"101","author":"A Gilhar","year":"1998","unstructured":"Gilhar A, Ullmann Y, Berkutzki T, Assy B, Kalish RS (1998) Alopecia areata transferred to human scalp explants on SCID mice with T-lymphocyte injections. J Clin Invest 101:62\u201367","journal-title":"J Clin Invest"},{"key":"668_CR4","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1046\/j.0022-202x.2001.01583.x","volume":"117","author":"A Gilhar","year":"2001","unstructured":"Gilhar A, Landau M, Assy B, Shalaginov R, Serafimovich S, Kalish RS (2001) Melanocyte associated T-cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on PrkdcSCID mice. J Invest Dermatol 117:1357\u20131362","journal-title":"J Invest Dermatol"},{"key":"668_CR5","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1001\/archderm.138.7.916","volume":"138","author":"A Gilhar","year":"2002","unstructured":"Gilhar A, Landau M, Assy B, Shalaginov R (2002) Mediation of alopecia areata by cooperation between CD4+ and CD8+ lymphocytes. Arch Dermatol 138:916\u2013922","journal-title":"Arch Dermatol"},{"key":"668_CR6","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1521-6616(02)00042-6","volume":"106","author":"A Gilhar","year":"2003","unstructured":"Gilhar A, Landau M, Assy B, Ullmann Y, Shalaginov R, Serafimovich S, Kalish RS (2003) Transfer of alopecia areata in the human scalp graft\/PrkdcSCID (SCID) mouse system is characterized by a TH1 response. Clin Immunol 106:181\u2013187","journal-title":"Clin Immunol"},{"key":"668_CR7","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.0022-202X.2004.23580.x","volume":"124","author":"A Gilhar","year":"2005","unstructured":"Gilhar A, Kam Y, Assy B, Kalish RS (2005) Alopecia areata induced in C3H\/HeJ mice by interferon-gamma: evidence for loss of immune privilege. J Invest Dermatol 124:288\u2013289","journal-title":"J Invest Dermatol"},{"key":"668_CR8","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/1523-1747.ep12395722","volume":"103","author":"R Hoffmann","year":"1994","unstructured":"Hoffmann R, Wenzel E, Huth A, van der Steen P, Schaufele M, Henninger HP, Happle R (1994) Cytokine mRNA levels in alopecia areata before and after treatment with contact allergen diphenylcyclopropenone. J Invest Dermatol 103:530\u2013533","journal-title":"J Invest Dermatol"},{"key":"668_CR9","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1046\/j.1365-2133.1999.02705.x","volume":"140","author":"KJ McElwee","year":"1999","unstructured":"McElwee KJ, Spiers EM, Oliver RF (1999) Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells. Br J Dermatol 140:432\u2013437","journal-title":"Br J Dermatol"},{"key":"668_CR10","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1111\/j.0022-202X.2005.23692.x","volume":"124","author":"KJ McElwee","year":"2005","unstructured":"McElwee KJ, Freyschmidt-Paul P, Hoffmann R, Kissling S, Hummel S, Vitacolonna M, Zoller M (2005) Transfer of CD8+ cells induces localized hair loss whereas CD4+\/CD25\u2212 cells promote systemic alopecia areata and CD4+\/CD25+ cells blocked disease onset in the C3H\/HeJ mouse model. J Invest Dermatol 124:947\u2013957","journal-title":"J Invest Dermatol"},{"key":"668_CR11","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1046\/j.1523-1747.2000.00156.x","volume":"115","author":"H Nagai","year":"2000","unstructured":"Nagai H, Hara I, Horikawa T, Oka M, Kamidono S, Ichihashi M (2000) Elimination of CD4T cells enhances antitumor effect of locally secreted interleukin-12 on B16 mouse melanoma and induces vitiligo-like coat color alteration. J Invest Dermatol 115:1059\u20131064","journal-title":"J Invest Dermatol"},{"key":"668_CR12","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.0906-6705.2004.00198.x","volume":"13","author":"H Nagai","year":"2004","unstructured":"Nagai H, Horikawa T, Hara I, Fukunaga A, Oniki S, Oka M, Nishigori C, Ichihashi M (2004) In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma when combined with interleukin-12 gene-transfer. Exp Dermatol 13:613\u2013620","journal-title":"Exp Dermatol"},{"key":"668_CR13","first-page":"541","volume":"66","author":"R Paus","year":"1994","unstructured":"Paus R, Slominski A, Czarnetzki BM (1994) Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? Yale J Biol Med 66:541\u2013554","journal-title":"Yale J Biol Med"},{"key":"668_CR14","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1046\/j.1523-1747.1998.00228.x","volume":"111","author":"R Ruckert","year":"1998","unstructured":"Ruckert R, Hoffmann U, van der Veen C, Bulfone-Paus S, Paus R (1998) MHC class I expression in murine skin: developmentally controlled and strikingly restricted intraepithelial expression during hair follicle morphogenesis and cycling, and response to cytokine treatment in vivo. J Invest Dermatol 111:25\u201330","journal-title":"J Invest Dermatol"},{"key":"668_CR15","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.4049\/jimmunol.155.3.1151","volume":"155","author":"S Sakaguchi","year":"1995","unstructured":"Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (1995) Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor \u03b1-chains (CD25); Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155:1151\u20131164","journal-title":"J Immunol"},{"key":"668_CR16","first-page":"843","volume":"23","author":"LP Thornburg","year":"1973","unstructured":"Thornburg LP, Stowe HD, Pick JR (1973) The pathogenesis of the alopecia due to hair chewing in mice. Lab Anim Sci 23:843\u2013850","journal-title":"Lab Anim Sci"},{"key":"668_CR17","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/1523-1747.ep12874660","volume":"94","author":"DJ Tobin","year":"1990","unstructured":"Tobin DJ, Fenton DA, Kendall MD (1990) Ultrastructural observations on the hair bulb melanocytes and melanosomes in acute alopecia areata. J Invest Dermatol 94:803\u2013807","journal-title":"J Invest Dermatol"},{"key":"668_CR18","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1600-0749.1996.tb00122.x","volume":"9","author":"DJ Tobin","year":"1996","unstructured":"Tobin DJ, Bystryn JC (1996) Different populations of melanocytes are present in hair follicles and epidermis. Pigment Cell Res 9:304\u2013310","journal-title":"Pigment Cell Res"},{"key":"668_CR19","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1084\/jem.20041130","volume":"200","author":"MJ Turk","year":"2004","unstructured":"Turk MJ, Guevara-Patino JA, Rizzuto GA, Engelhorn ME, Houghton AN (2004) Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med 200:771\u2013782","journal-title":"J Exp Med"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-006-0668-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00403-006-0668-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-006-0668-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,7]],"date-time":"2023-05-07T19:29:14Z","timestamp":1683487754000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00403-006-0668-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,20]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["668"],"URL":"https:\/\/doi.org\/10.1007\/s00403-006-0668-y","relation":{},"ISSN":["0340-3696","1432-069X"],"issn-type":[{"value":"0340-3696","type":"print"},{"value":"1432-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,20]]}}}