{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T16:55:18Z","timestamp":1774976118274,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2008,8,2]],"date-time":"2008-08-02T00:00:00Z","timestamp":1217635200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1007\/s00403-008-0877-7","type":"journal-article","created":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T09:23:05Z","timestamp":1217582585000},"page":"595-600","source":"Crossref","is-referenced-by-count":16,"title":["Changes in Na+, K+ concentrations in perspiration and perspiration volume with alternating current iontophoresis in palmoplantar hyperhidrosis patients"],"prefix":"10.1007","volume":"300","author":[{"given":"Yuichiro","family":"Ohshima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Yanagishita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Tamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Sugenoya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Tsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinari","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,8,2]]},"reference":[{"key":"877_CR1","first-page":"346","volume":"69","author":"JC Dahl","year":"1989","unstructured":"Dahl JC, Glent-Madsen L (1989) Treatment of hyperhidrosis manuum by tap water iontophoresis. Acta Derm Venereol 69:346\u2013348","journal-title":"Acta Derm Venereol"},{"key":"877_CR2","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1001\/archderm.1957.01550170021004","volume":"75","author":"RL Dobson","year":"1957","unstructured":"Dobson RL (1957) Some histochemical observations on the human eccrine sweat glands. Arch Dermatol 75:653\u2013666","journal-title":"Arch Dermatol"},{"key":"877_CR3","first-page":"69","volume":"28","author":"AC Hill","year":"1981","unstructured":"Hill AC, Baker GF, Jansen GT (1981) Mechanism of action of iontophoresis in the treatment of palmar hyperhidrosis. Cutis 28:69\u201372","journal-title":"Cutis"},{"key":"877_CR4","first-page":"101","volume":"25","author":"T Ichihashi","year":"1936","unstructured":"Ichihashi T (1936) Effect of drugs on the sweat glands by cataphoresis, and an effective method for suppression of local sweating. J Orient Med 25:101\u2013102","journal-title":"J Orient Med"},{"key":"877_CR5","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0165-1838(97)00014-3","volume":"64","author":"S Iwase","year":"1997","unstructured":"Iwase S, Ikeda T, Kitazawa H, Hakusui S, Sugenoya J, Mano T (1997) Altered response in cutaneous sympathetic outflow to mental and thermal stimuli in primary palmoplantar hyperhidrosis. J Auton Nerv Syst 64:65\u201373","journal-title":"J Auton Nerv Syst"},{"key":"877_CR6","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1159\/000250345","volume":"161","author":"O Jensen","year":"1980","unstructured":"Jensen O, Karlsmark T (1980) Palmoplantar hyperhidrosis treatment with alcohol solution of aluminium chloride hexahydrate: a simple method of transpiration measurement. Dermatologica 161:133\u2013135","journal-title":"Dermatologica"},{"key":"877_CR7","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1001\/archderm.1968.01610170065013","volume":"98","author":"F Levit","year":"1968","unstructured":"Levit F (1968) Simple device for treatment of hyperhidrosis by iontophoresis. Arch Dermatol 98:505\u2013507","journal-title":"Arch Dermatol"},{"key":"877_CR8","first-page":"84","volume":"51","author":"T-S Lin","year":"2002","unstructured":"Lin T-S, Kuo S-J, Chou M-C (2002) Uniportal endoscopic thoracic sympathectomy for treatment of palmar and axillary hyperhidrosis: Analysis of 2000 cases. Neurosurgery 51:84\u201387","journal-title":"Neurosurgery"},{"key":"877_CR9","first-page":"822","volume":"28","author":"NJ Lowe","year":"2002","unstructured":"Lowe NJ, Yamauchi PS, Lask GP, Patnaik R, Iyer S (2002) Efficacy and safety of botulinum toxin type A in the treatment of palmar hyperhidrosis: a double-blind, randomized, placebo-controlled study. Dermatol Surg 28:822\u2013827","journal-title":"Dermatol Surg"},{"key":"877_CR10","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1152\/ajplegacy.1973.224.5.1235","volume":"224","author":"JA Mangos","year":"1973","unstructured":"Mangos JA (1973) Transductal fluxes of Na, K and water in the human eccrine sweat glands. Am J Physiol 224:1235\u20131240","journal-title":"Am J Physiol"},{"key":"877_CR11","first-page":"1611","volume-title":"The physiology and pathophysiology of the skin","author":"T Morimoto","year":"1978","unstructured":"Morimoto T (1978) Sweat secretion. In: Jarrett A (ed) The physiology and pathophysiology of the skin. Academic Press, London, pp 1611\u20131621"},{"key":"877_CR12","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1365-2133.1993.tb03521.x","volume":"129","author":"S Reinauer","year":"1993","unstructured":"Reinauer S, Neusser A, Schauf G, H\u00f6lzle E (1993) Iontophoresis with alternating current and direct current offset (AC\/DC iontophoresis): a new approach for the treatment of hyperhidrosis. Br J Dermatol 129:166\u2013169","journal-title":"Br J Dermatol"},{"key":"877_CR13","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1212\/WNL.57.11.2095","volume":"57","author":"D Saadia","year":"2001","unstructured":"Saadia D, Voustianiouk A, Wang AK, Kaufmann H (2001) Botulinum toxin type A in primary palmar hyperhidrosis: randomized, single-blind, two-dose study. Neurology 57:2095\u20132099","journal-title":"Neurology"},{"key":"877_CR14","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BFb0037089","volume":"79","author":"K Sato","year":"1977","unstructured":"Sato K (1977) The physiology, pharmacology, and biochemistry of the eccrine sweat gland. Rev Physiol Biochem Pharmacol 79:51\u2013131","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"877_CR15","first-page":"97","volume-title":"Clinical autonomic disorders: evaluation and management","author":"K Sato","year":"1997","unstructured":"Sato K (1997) Normal and abnormal sweat gland function. In: Phillip AL (ed) Clinical autonomic disorders: evaluation and management, 2nd edn. Lippincott-Raven, Philadelphia, pp 97\u2013108","edition":"2"},{"key":"877_CR16","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/1523-1747.ep12259279","volume":"54","author":"K Sato","year":"1970","unstructured":"Sato K, Dobson RL (1970) The effect of intracutaneous d-aldosterone and hydrocortisone on human eccrine sweat gland function. J Invest Dermatol 54:450\u2013462","journal-title":"J Invest Dermatol"},{"key":"877_CR17","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0190-9622(89)70063-3","volume":"20","author":"K Sato","year":"1989","unstructured":"Sato K, Kang WH, Saga K, Sato KT (1989) Biology of sweat glands and their disorders I. Normal sweat gland function. J Am Acad Dermatol 20:537\u2013563","journal-title":"J Am Acad Dermatol"},{"key":"877_CR18","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1152\/jappl.1993.75.5.2258","volume":"75","author":"K Sato","year":"1993","unstructured":"Sato K, Timm DE, Sato F, Templeton EA, Meletiou DS, Toyomoto T, Soos G, Sato SK (1993) Generation and transit pathway of H+ is critical for inhibition of palmar sweating by iontophoresis in water. J Appl Physiol 75:2258\u20132264","journal-title":"J Appl Physiol"},{"key":"877_CR19","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/j.1346-8138.2003.tb00414.x","volume":"30","author":"H Shimizu","year":"2003","unstructured":"Shimizu H, Tamada Y, Shimizu J, Ohshima Y, Matsumoto Y, Sugenoya J (2003) Effectiveness of iontophoresis with alternating current (AC) in the treatment of patients with palmoplantar hyperhidrosis. J Dermatol 30:444\u2013449","journal-title":"J Dermatol"},{"key":"877_CR20","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1001\/archderm.1987.01660310061015","volume":"123","author":"LP Stolman","year":"1987","unstructured":"Stolman LP (1987) Treatment of excess sweating of the palms by iontophoresis. Arch Dermatol 123:893\u2013896","journal-title":"Arch Dermatol"},{"key":"877_CR21","first-page":"863","volume":"16","author":"LP Stolman","year":"1998","unstructured":"Stolman LP (1998) Treatment of hyperhidrosis. Curr Ther 16:863\u2013867","journal-title":"Curr Ther"},{"key":"877_CR22","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/1099-0801(200012)14:8<505::AID-BMC17>3.0.CO;2-7","volume":"14","author":"T Tsuda","year":"2000","unstructured":"Tsuda T, Noda S, Kitagawa S, Morishita T (2000) Proposal of sampling process for collecting human sweat and determination of caffeine concentration in it by using GC\/MS. Biomed Chromatogr 14:505\u2013510","journal-title":"Biomed Chromatogr"},{"key":"877_CR23","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1159\/000051780","volume":"203","author":"J Vadoud-Seyedi","year":"2001","unstructured":"Vadoud-Seyedi J, Heenen M, Simonart T (2001) Treatment of idiopathic palmar hyperhidrosis with botulinum toxin. Report of 23 cases and review of the literature. Dermatology 203:318\u2013321","journal-title":"Dermatology"},{"key":"877_CR24","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1067\/mtc.2000.107830","volume":"120","author":"H Yamamoto","year":"2000","unstructured":"Yamamoto H, Kanehira A, Kawamura M, Okada M, Ohkita Y (2000) Needlescopic surgery for palmar hyperhidrosis. J Thorac Cardiovasc Surg 120:276\u2013279","journal-title":"J Thorac Cardiovasc Surg"},{"key":"877_CR25","first-page":"583","volume":"102","author":"H Yokozeki","year":"1992","unstructured":"Yokozeki H, Oshiro Y, Katayama I, Nishioka K, Kinoshita M, Nishiyama S (1992) The clinical evaluation of the treatment of palmoplantar hyperhidrosis by tap water iontophoresis. Jpn J Dermatol 102:583\u2013586","journal-title":"Jpn J Dermatol"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-008-0877-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00403-008-0877-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-008-0877-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T17:37:39Z","timestamp":1559065059000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00403-008-0877-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,2]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["877"],"URL":"https:\/\/doi.org\/10.1007\/s00403-008-0877-7","relation":{},"ISSN":["0340-3696","1432-069X"],"issn-type":[{"value":"0340-3696","type":"print"},{"value":"1432-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8,2]]}}}