{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T20:58:33Z","timestamp":1762808313055},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T00:00:00Z","timestamp":1424736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1007\/s00403-015-1553-3","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T12:41:45Z","timestamp":1424695305000},"page":"439-444","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Serum homocysteine, asymmetric dimethyl arginine (ADMA) and other arginine\u2013NO pathway metabolite levels in patients with psoriasis"],"prefix":"10.1007","volume":"307","author":[{"given":"\u00d6zlem","family":"Bilgi\u00e7","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilmi Cevdet","family":"Alt\u0131nyazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice","family":"Baran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"\u00dcnl\u00fc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,2,24]]},"reference":[{"key":"1553_CR1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1365-2133.2010.09766.x","volume":"163","author":"S Abeyakirthi","year":"2010","unstructured":"Abeyakirthi S, Mowbray M, Bredenkamp N et al (2010) Arginase is overactive in psoriatic skin. Br J Dermatol 163:193\u2013196","journal-title":"Br J Dermatol"},{"key":"1553_CR2","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.atherosclerosis.2012.08.033","volume":"225","author":"K Angel","year":"2012","unstructured":"Angel K, Provan SA, Mowinckel P et al (2012) The l-arginine\/asymmetric dimethylarginine ratio is improved by anti-tumor necrosis factor-\u03b1 therapy in inflammatory arthropathies. Associations with aortic stiffness. Atherosclerosis 225:160\u2013165","journal-title":"Atherosclerosis"},{"key":"1553_CR3","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.3899\/jrheum.100893","volume":"38","author":"F Atzeni","year":"2011","unstructured":"Atzeni F, Sarzi-Puttini P, Sitia S et al (2011) Coronary flow reserve and asymmetric dimethylarginine levels: new measurements for identifying subclinical atherosclerosis in patients with psoriatic arthritis. J Rheumatol 38:1661\u20131664","journal-title":"J Rheumatol"},{"key":"1553_CR4","doi-asserted-by":"crossref","first-page":"148","DOI":"10.4081\/reumatismo.2011.148","volume":"63","author":"F Atzeni","year":"2011","unstructured":"Atzeni F, Turiel M, Boccassini L et al (2011) Cardiovascular involvement in psoriatic arthritis. Reumatismo 63:148\u2013154","journal-title":"Reumatismo"},{"key":"1553_CR5","first-page":"159","volume":"58","author":"J Be\u0142towski","year":"2006","unstructured":"Be\u0142towski J, Kedra A (2006) Asymmetric dimethylarginine (ADMA) as a target for pharmacotherapy. Pharmacol Rep 58:159\u2013178","journal-title":"Pharmacol Rep"},{"key":"1553_CR6","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1177\/039463201002300327","volume":"23","author":"V Brazzelli","year":"2010","unstructured":"Brazzelli V, Grasso V, Fornara L et al (2010) Homocysteine, vitamin B12 and folic acid levels in psoriatic patients and correlation with disease severity. Int J Immunopathol Pharmacol 23:911\u2013916","journal-title":"Int J Immunopathol Pharmacol"},{"key":"1553_CR7","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0002-9440(10)63811-4","volume":"162","author":"D Bruch-Gerharz","year":"2003","unstructured":"Bruch-Gerharz D, Schnorr O, Suschek C et al (2003) Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation. Am J Pathol 162:203\u2013211","journal-title":"Am J Pathol"},{"key":"1553_CR8","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1468-3083.2008.03024.x","volume":"23","author":"SK Cakmak","year":"2009","unstructured":"Cakmak SK, G\u00fcl U, Kili\u00e7 C et al (2009) Homocysteine, vitamin B12 and folic acid levels in psoriasis patients. J Eur Acad Dermatol Venereol 23:300\u2013303","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1553_CR9","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.aca.2010.08.011","volume":"677","author":"IM Gangi Di","year":"2010","unstructured":"Di Gangi IM, Chiandetti L, Gucciardi A et al (2010) Simultaneous quantitative determination of N(G), N(G)-dimethyl-l-arginine or asymmetric dimethylarginine and related pathway\u2019s metabolites in biological fluids by ultrahigh-performance liquid chromatography\/electrospray ionization-tandem mass spectrometry. Anal Chim Acta 677:140\u2013148","journal-title":"Anal Chim Acta"},{"key":"1553_CR10","first-page":"661","volume":"24","author":"Fathy H El-Mongy","year":"2010","unstructured":"El-Mongy Fathy H, Abdelaziz A et al (2010) Subclinical atherosclerosis in patients with chronic psoriasis: a potential association. JEADV 24:661\u2013666","journal-title":"JEADV"},{"key":"1553_CR11","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/ijd.12397","volume":"53","author":"I Erturan","year":"2014","unstructured":"Erturan I, K\u00f6ro\u011flu BK, Adilo\u011flu A et al (2014) Evaluation of serum sCD40L and homocysteine levels with subclinical atherosclerosis indicators in patients with psoriasis: a pilot study. Int J Dermatol 53:503\u2013509","journal-title":"Int J Dermatol"},{"key":"1553_CR12","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1046\/j.1523-1747.1998.00268.x","volume":"111","author":"V Krischel","year":"1998","unstructured":"Krischel V, Bruch-Gerharz D, Suschek C et al (1998) Biphasic effect of exogenous nitric oxide on proliferation and differentiation in skin derived keratinocytes but not fibroblasts. J Invest Dermatol 111:286\u2013291","journal-title":"J Invest Dermatol"},{"key":"1553_CR13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S1567-5688(03)00035-7","volume":"4","author":"SR Lentz","year":"2003","unstructured":"Lentz SR, Rodionov RN, Dayal S (2003) Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA. Atheroscler Suppl 4:61\u201365","journal-title":"Atheroscler Suppl"},{"key":"1553_CR14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2891-11-1","volume":"11","author":"SC Liew","year":"2012","unstructured":"Liew SC, Das-Gupta E, Wong SF et al (2012) Association of methylentetraydrofolate reductase (MTHFR) 677 C>T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study. Nutr J 11:1","journal-title":"Nutr J"},{"key":"1553_CR15","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/j.1365-2133.2006.07503.x","volume":"155","author":"M Malerba","year":"2006","unstructured":"Malerba M, Gisondi P, Radaeli A et al (2006) Plasma homocysteine and folate levels in patients with chronic plaque psoriasis. Br J Dermatol 155:1165\u20131169","journal-title":"Br J Dermatol"},{"key":"1553_CR16","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1001\/archderm.1973.01620210078025","volume":"107","author":"CJ McDonald","year":"1973","unstructured":"McDonald CJ, Calabresi P (1973) Thromboembolic disorders associated with psoriasis. Arch Dermatol 107:918","journal-title":"Arch Dermatol"},{"key":"1553_CR17","doi-asserted-by":"crossref","first-page":"965385","DOI":"10.1155\/2012\/965385","volume":"2012","author":"I McDonald","year":"2012","unstructured":"McDonald I, Connolly M, Tobin AM (2012) A review of psoriasis, a known risk factor for cardiovascular disease and its impact on folate and homocysteine metabolism. J Nutr Metab 2012:965385","journal-title":"J Nutr Metab"},{"key":"1553_CR18","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.2174\/1381612043382765","volume":"10","author":"S Nadar","year":"2004","unstructured":"Nadar S, Blann AD, Lip GY (2004) Endothelial dysfunction: methods of assessment and application to hypertension. Curr Pharm Des 10:3591\u20133605","journal-title":"Curr Pharm Des"},{"key":"1553_CR19","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1529-8019.2010.01304.x","volume":"23","author":"L Naldi","year":"2010","unstructured":"Naldi L, Mercuri SR (2010) Epidemiology of comorbidities in psoriasis. Dermatol Ther 23:114\u2013118","journal-title":"Dermatol Ther"},{"key":"1553_CR20","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1046\/j.1365-2133.2000.03483.x","volume":"142","author":"AD Ormerod","year":"2000","unstructured":"Ormerod AD, Copeland P, Shah SA (2000) Treatment of psoriasis with topical NG-monomethyl-l-arginine, an inhibitor of nitric oxide synthesis. Br J Dermatol 142:985\u2013990","journal-title":"Br J Dermatol"},{"key":"1553_CR21","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s00431-010-1366-5","volume":"170","author":"O Ozdemir","year":"2011","unstructured":"Ozdemir O, Yakut A, Dinleyici EC (2011) Serum asymmetric dimethylarginine (ADMA), homocysteine, vitamin B(12), folate levels, and lipid profiles in epileptic children treated with valproic acid. Eur J Pediatr 170:873\u2013877","journal-title":"Eur J Pediatr"},{"key":"1553_CR22","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.niox.2011.03.002","volume":"24","author":"I Palomo","year":"2011","unstructured":"Palomo I, Contreras A, Alarc\u00f3n LM et al (2011) Elevated concentration of asymmetric dimethylarginine (ADMA) in individuals with metabolic syndrome. Nitric Oxide 24:224\u2013228","journal-title":"Nitric Oxide"},{"key":"1553_CR23","first-page":"1392","volume":"41","author":"O Stanger","year":"2003","unstructured":"Stanger O, Herrmann W, Pietrzik K et al (2003) DACH-LIGA Homocystein e.V. DACH-LIGA homocystein (German, Austrian and Swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med 41:1392\u20131403","journal-title":"Clin Chem Lab Med"},{"key":"1553_CR24","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1161\/hc4601.098514","volume":"104","author":"MC St\u00fchlinger","year":"2001","unstructured":"St\u00fchlinger MC, Tsao PS, Her JH et al (2001) Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation 104:2569\u20132575","journal-title":"Circulation"},{"key":"1553_CR25","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1365-2230.2010.03877.x","volume":"36","author":"AM Tobin","year":"2011","unstructured":"Tobin AM, Hughes R, Hand EB et al (2011) Homocysteine status and cardiovascular risk factors in patients with psoriasis: a case-control study. Clin Exp Dermatol 36:19\u201323","journal-title":"Clin Exp Dermatol"},{"key":"1553_CR26","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.clinbiochem.2011.06.007","volume":"44","author":"M Usta","year":"2011","unstructured":"Usta M, Yurdakul S, Aral H et al (2011) Vascular endothelial function assessed by a noninvasive ultrasound method and serum asymmetric dimethylarginine concentrations in mild-to-moderate plaque-type psoriatic patients. Clin Biochem 44:1080\u20131084","journal-title":"Clin Biochem"},{"key":"1553_CR27","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1042\/CS20100595","volume":"121","author":"LP Zwan van der","year":"2011","unstructured":"van der Zwan LP, Scheffer PG, Dekker JM et al (2011) Systemic inflammation is linked to low arginine and high ADMA plasma levels resulting in an unfavourable NOS substrate-to-inhibitor ratio: the Hoorn study. Clin Sci (Lond) 121:71\u201378","journal-title":"Clin Sci (Lond)"},{"key":"1553_CR28","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1515\/CCLM.2007.340","volume":"45","author":"C Guldener van","year":"2007","unstructured":"van Guldener C, Nanayakkara PW, Stehouwer CD (2007) Homocysteine and asymmetric dimethylarginine (ADMA): biochemically linked but differently related to vascular disease in chronic kidney disease. Clin Chem Lab Med 45:1683\u20131687","journal-title":"Clin Chem Lab Med"},{"key":"1553_CR29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0009-8981(03)00082-2","volume":"332","author":"B Vanizor Kural","year":"2003","unstructured":"Vanizor Kural B, Orem A, Cim\u015fit G et al (2003) Plasma homocysteine and its relationships with atherothrombotic markers in psoriatic patients. Clin Chim Acta 332:23\u201330","journal-title":"Clin Chim Acta"},{"key":"1553_CR30","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1093\/eurjhf\/hfq158","volume":"12","author":"M Visser","year":"2010","unstructured":"Visser M, Paulus WJ, Vermeulen MA et al (2010) The role of asymmetric dimethylarginine and arginine in the failing heart and its vasculature. Eur J Heart Fail 12:1274\u20131281","journal-title":"Eur J Heart Fail"},{"key":"1553_CR31","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1161\/ATVBAHA.109.185645","volume":"29","author":"WH Wang Tang","year":"2009","unstructured":"Wang Tang WH, Cho L et al (2009) Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. Arterioscler Thromb Vasc Biol 29:1383\u20131391","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-015-1553-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00403-015-1553-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-015-1553-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T13:05:44Z","timestamp":1651323944000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00403-015-1553-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,24]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["1553"],"URL":"https:\/\/doi.org\/10.1007\/s00403-015-1553-3","relation":{},"ISSN":["0340-3696","1432-069X"],"issn-type":[{"value":"0340-3696","type":"print"},{"value":"1432-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,24]]}}}