{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T16:07:14Z","timestamp":1775491634889,"version":"3.50.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T00:00:00Z","timestamp":1477353600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004919","name":"King Abdulaziz City for Science and Technology","doi-asserted-by":"publisher","award":["8-MED114-03"],"award-info":[{"award-number":["8-MED114-03"]}],"id":[{"id":"10.13039\/501100004919","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1007\/s00403-016-1695-y","type":"journal-article","created":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T10:40:25Z","timestamp":1477392025000},"page":"31-42","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Epidermal hydrogen peroxide is not increased in lesional and non-lesional skin of vitiligo"],"prefix":"10.1007","volume":"309","author":[{"given":"Mohammad Z.","family":"Zailaie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,10,25]]},"reference":[{"key":"1695_CR1","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1038\/sj.jid.5700340","volume":"126","author":"DR Bickers","year":"2006","unstructured":"Bickers DR, Athar M (2006) Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol 126:2565\u20132575","journal-title":"J Invest Dermatol"},{"key":"1695_CR2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1600-0749.2004.00130.x","volume":"17","author":"RE Boissy","year":"2004","unstructured":"Boissy RE, Manga P (2004) On the etiology of contact\/occupational vitiligo. Pigment Cell Res 17:208\u2013214","journal-title":"Pigment Cell Res"},{"key":"1695_CR3","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1111\/j.1468-3083.2011.04343.x","volume":"26","author":"S Briganti","year":"2012","unstructured":"Briganti S, Caron-Schreinemachers AL, Picardo M, Westerhof W (2012) Anti-oxidant defence mechanism in vitiliginous skin increases with skin type. J Euro Acad Dermatol Venereol 26:1212\u20131219","journal-title":"J Euro Acad Dermatol Venereol"},{"key":"1695_CR4","first-page":"421","volume-title":"Infrared and Raman spectroscopy of biological materials","author":"EA Carter","year":"2001","unstructured":"Carter EA, Edwards HGM (2001) Biological applications of Raman spectroscopy. In: Gremlich Hans-Ulrich, Yan Bing (eds) Infrared and Raman spectroscopy of biological materials. Marcel Dekker Inc, New York, pp 421\u2013473"},{"key":"1695_CR5","doi-asserted-by":"crossref","first-page":"3755","DOI":"10.1002\/art.21480","volume":"52","author":"S Cuzzocrea","year":"2005","unstructured":"Cuzzocrea S, Mazzon E, di Paola R et al (2005) Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance. Arthritis Rheum 52:3755\u20133760","journal-title":"Arthritis Rheum"},{"key":"1695_CR6","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.freeradbiomed.2014.02.006","volume":"70","author":"AB Das","year":"2014","unstructured":"Das AB, Nauser T, Koppenol WH et al (2014) Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide with subsequent glutathione addition. Free Radic Biol Med 70:86\u201395","journal-title":"Free Radic Biol Med"},{"key":"1695_CR7","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1034\/j.1600-0749.2003.00087.x","volume":"16","author":"ML Dell\u2019 Anna","year":"2003","unstructured":"Dell\u2019 Anna ML, Urbanelli S, Mastrofrancesco A et al (2003) Alterations of mitochondria in peripheral blood mononuclear cells of vitiligo patients. Pigment Cell Res 16:553\u2013559","journal-title":"Pigment Cell Res"},{"key":"1695_CR8","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1161\/CIRCRESAHA.109.214601","volume":"107","author":"AE Dikalova","year":"2010","unstructured":"Dikalova AE, Bikeyeva AT, Budzyn K et al (2010) Therapeutic targeting of mitochondrial superoxide in hypertension. Circ Res 107:106\u2013116","journal-title":"Circ Res"},{"key":"1695_CR9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1089\/ars.2010.3682","volume":"15","author":"MJ Faulkner","year":"2011","unstructured":"Faulkner MJ, Helmann JD (2011) Peroxide stress elicits adaptive changes in bacterial metal ion homeostasis. Antioxid Redox Signal 15:175\u2013189","journal-title":"Antioxid Redox Signal"},{"key":"1695_CR10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1042\/CS20090603","volume":"120","author":"SJ Glassman","year":"2011","unstructured":"Glassman SJ (2011) Vitiligo, reactive oxygen species and T-cells. Clin Sci (Lond) 120:99\u2013120","journal-title":"Clin Sci (Lond)"},{"key":"1695_CR11","first-page":"469","volume":"54","author":"TJ Guzik","year":"2003","unstructured":"Guzik TJ, Korbut R, Adamek-Guzik T (2003) Nitric oxide and superoxide in inflammation and immune regulation. J Physiol Pharmacol 54:469\u2013487","journal-title":"J Physiol Pharmacol"},{"key":"1695_CR12","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/0891-5849(89)90064-6","volume":"6","author":"EPL Hunter","year":"1989","unstructured":"Hunter EPL, Desrosiers MF, Simic MG (1989) The effect of oxygen, antioxidants and superoxide radical on tyrosine phenoxyl dimerization. Free Radic Biol Med 6:581\u2013585","journal-title":"Free Radic Biol Med"},{"key":"1695_CR13","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/0014-5793(95)00873-8","volume":"371","author":"S Inoue","year":"2005","unstructured":"Inoue S, Kawanishi S (2005) Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Lett 371:86\u201388","journal-title":"FEBS Lett"},{"key":"1695_CR14","first-page":"47","volume":"145","author":"MG Kosmadaki","year":"2010","unstructured":"Kosmadaki MG, Naif A, Hee-Young P (2010) Recent progress in understanding pigmentation. G Ital Dermatol Venereol 145:47\u201355","journal-title":"G Ital Dermatol Venereol"},{"key":"1695_CR15","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1074\/jbc.M310341200","volume":"279","author":"AP Kudin","year":"2004","unstructured":"Kudin AP, Bimpong-Buta NY, Vielhaber S et al (2004) Characterization of superoxide-producing sites in isolated brain mitochondria. J Biol Chem 279:4127\u20134135","journal-title":"J Biol Chem"},{"key":"1695_CR16","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.freeradbiomed.2013.08.189","volume":"65","author":"NC Laddha","year":"2013","unstructured":"Laddha NC, Dwivedi M, Gani AR, Shajil EM, Begum R (2013) Involvement of superoxide dismutase isoenzymes and their genetic variants in progression of and higher susceptibility to vitiligo. Free Radic Biol Med 65:1110\u20131125","journal-title":"Free Radic Biol Med"},{"key":"1695_CR17","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1111\/j.1742-4658.2005.04661.x","volume":"272","author":"M Mastore","year":"2005","unstructured":"Mastore M, Kohler L, Nappi AJ (2005) Production and utilization of hydrogen peroxide associated with melanogenesis and tyrosinase mediated oxidations of DOPA and dopamine. FEBS J 272:2407\u20132415","journal-title":"FEBS J"},{"key":"1695_CR18","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1034\/j.1600-0749.2001.140303.x","volume":"14","author":"FL Meyskens","year":"2001","unstructured":"Meyskens FL, Farmer P, Frueauf JP (2001) Redox regulation in human melanocytes and melanoma. Pigment Cell Res 14:148\u2013154","journal-title":"Pigment Cell Res"},{"key":"1695_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20081386","volume":"417","author":"MP Murphy","year":"2009","unstructured":"Murphy MP (2009) How mitochondria produce reactive oxygen species. Biochem J 417:1\u201313","journal-title":"Biochem J"},{"key":"1695_CR20","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/00008390-199610000-00001","volume":"6","author":"AJ Nappi","year":"1996","unstructured":"Nappi AJ, Vass E (1996) Hydrogen peroxide generation associated with the oxidations of the eumelanin precursors 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. Melanoma Res 6:341\u2013349","journal-title":"Melanoma Res"},{"key":"1695_CR21","first-page":"407","volume":"135","author":"MD Njoo","year":"1999","unstructured":"Njoo MD, Das PK, Bos JD, Westerhof W (1999) Association of the Koebner phenomenon with disease activity and therapeutic responsiveness in vitiligo vulgaris. Arch Dermatol 135:407\u2013413","journal-title":"Arch Dermatol"},{"key":"1695_CR22","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1007\/s10495-007-0756-2","volume":"12","author":"M Ott","year":"2007","unstructured":"Ott M, Gogvadze V, Orrenius S, Zhivotovsky B (2007) Mitochondria, oxidative stress and cell death. Apoptosis 12:913\u2013922","journal-title":"Apoptosis"},{"key":"1695_CR23","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1046\/j.1365-2133.2003.05440.x","volume":"149","author":"D Parsad","year":"2003","unstructured":"Parsad D, Wakamatsu K, Kanwar AJ et al (2003) Eumelanin and phaeomelanin contents of depigmented and repigmented skin in vitiligo patients. Br J Dermatol 149:624\u2013626","journal-title":"Br J Dermatol"},{"key":"1695_CR24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1600-0749.1998.tb00714.x","volume":"11","author":"S Passi","year":"1998","unstructured":"Passi S, Grandinetti M, Maggio F et al (1998) Epidermal oxidative stress in vitiligo. Pigment Cell Res 11:81\u201385","journal-title":"Pigment Cell Res"},{"key":"1695_CR25","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1034\/j.1600-0749.2000.130412.x","volume":"13","author":"G Prota","year":"2000","unstructured":"Prota G (2000) Melanins melanogenesis and melanocytes: looking at their functional significance from the chemist\u2019s viewpoint. Pigment Cell Res 13:283\u2013293","journal-title":"Pigment Cell Res"},{"key":"1695_CR26","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0891-5849(00)00338-5","volume":"29","author":"S Raha","year":"2000","unstructured":"Raha S, McEachern GE, Myint AT, Robinson BH (2000) Superoxides from mitochondrial complex III: the role of manganese superoxide dismutase. Free Rad Biol Med 29:170\u2013180","journal-title":"Free Rad Biol Med"},{"key":"1695_CR27","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1172\/JCI118623","volume":"97","author":"S Rajagoplan","year":"1996","unstructured":"Rajagoplan S, Kuz S, M\u00fcnzel T et al (1996) Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH\/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J Clin Invest 97:1916\u20131923","journal-title":"J Clin Invest"},{"key":"1695_CR28","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1126\/science.1130481","volume":"312","author":"SG Rhee","year":"2006","unstructured":"Rhee SG (2006) H2O2, a necessary evil for signaling. Science 312:1882\u20131883","journal-title":"Science"},{"key":"1695_CR29","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1089\/ars.2005.7.619","volume":"7","author":"SG Rhee","year":"2005","unstructured":"Rhee SG, Yang KS, Kang SW, Woo HA, Chang TS (2005) Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification. Antioxid Redox Signal 7:619\u2013622","journal-title":"Antioxid Redox Signal"},{"key":"1695_CR30","doi-asserted-by":"crossref","first-page":"3790","DOI":"10.1096\/fj.09-132621","volume":"23","author":"MM Salem","year":"2009","unstructured":"Salem MM, Shalbaf M, Gibbons NC et al (2009) Enhanced DNA binding capacity on up-regulated epidermal wild-type P53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage. FASEB J 23:3790\u20133807","journal-title":"FASEB J"},{"key":"1695_CR31","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1006\/bbrc.1995.2578","volume":"24","author":"MG Salgo","year":"1995","unstructured":"Salgo MG, Squadrito GL, Pryor WA (1995) Peroxynitrate causes apoptosis in rat thymocytes. Biochem Biophys Res Commun 24:1111\u20131118","journal-title":"Biochem Biophys Res Commun"},{"key":"1695_CR32","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1523-1747.2001.00220.x","volume":"116","author":"KU Schallreuter","year":"2001","unstructured":"Schallreuter KU, Moore J, Wood JM et al (2001) Epidermal H2O2 accumulation alters tetrahydrobiopterin (6BH4) recycling in vitiligo: identification of a general mechanism in regulation of all 6BH4-dependent processes? J Invest Dermatol 116:167\u2013174","journal-title":"J Invest Dermatol"},{"key":"1695_CR33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/sj.jidsp.5640189","volume":"4","author":"KU Schallreuter","year":"1999","unstructured":"Schallreuter KU, Moore J, Wood JM et al (1999) In vivo and in vitro evidence for hydrogen peroxide(H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. J Invest Dermatol Symp Proc 4:91\u201396","journal-title":"J Invest Dermatol Symp Proc"},{"key":"1695_CR34","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1046\/j.1365-4362.2002.01463.x","volume":"41","author":"KU Schallreuter","year":"2002","unstructured":"Schallreuter KU, Moore J, Behrens-Williams S et al (2002) Rapid initiation of repigmentation of vitiligo with dead sea climatotherapy in combination with pseudocatalase (PC-KUS). Int J Dermatol 41:482\u2013487","journal-title":"Int J Dermatol"},{"key":"1695_CR35","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/jrs.868","volume":"33","author":"KU Schallreuter","year":"2002","unstructured":"Schallreuter KU, Moore J, Behrens-Williams S et al (2002) In vitro and in vivo identification of pseudocatalase activity in Dead Sea water using Fourier transform Raman spectroscopy. J Raman Spectosc 33:586\u2013592","journal-title":"J Raman Spectosc"},{"key":"1695_CR36","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/1523-1747.ep12492612","volume":"97","author":"KU Schallreuter","year":"1991","unstructured":"Schallreuter KU, Wood JM, Berger J (1991) Low catalase levels in the epidermis of patients with vitiligo. J Invest Dermatol 97:1081\u20131085","journal-title":"J Invest Dermatol"},{"key":"1695_CR37","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0197-0186(95)00122-0","volume":"29","author":"JB Schulz","year":"1996","unstructured":"Schulz JB, Henshaw DR, MacGarvey U, Beal MF (1996) Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity. Neurochem Int 29:167\u2013171","journal-title":"Neurochem Int"},{"key":"1695_CR38","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0006-8993(97)00429-0","volume":"765","author":"TS Smith","year":"1997","unstructured":"Smith TS, Bennett JP Jr (1997) Mitochondrial toxins in models of neurodegenerative diseases. I In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or\u00a0azide ions. Brain Res 765:183\u2013188","journal-title":"Brain Res"},{"key":"1695_CR39","doi-asserted-by":"crossref","first-page":"268","DOI":"10.4103\/0378-6323.48427","volume":"75","author":"PV Sravani","year":"2009","unstructured":"Sravani PV, Babu NK, Gopal KV et al (2009) Determination of oxidative stress in vitiligo by measuring superoxide dismutase and catalase levels in vitiliginous and non-vitiliginous skin. Indian J Dermatol Venereol Leprol 75:268\u2013271","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"1695_CR40","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1089\/ars.2006.8.243","volume":"8","author":"JR Stone","year":"2006","unstructured":"Stone JR, Yang S (2006) Hydrogen peroxide: a signaling messenger. Antiox Redox Signal 8:243\u2013270","journal-title":"Antiox Redox Signal"},{"key":"1695_CR41","doi-asserted-by":"crossref","first-page":"8520","DOI":"10.1128\/MCB.25.19.8520-8530.2005","volume":"25","author":"P Storz","year":"2005","unstructured":"Storz P, D\u00f6ppler H, Toker A (2005) Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species. Mol Cell Biol 25:8520\u20138530","journal-title":"Mol Cell Biol"},{"key":"1695_CR42","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.freeradbiomed.2011.11.019","volume":"52","author":"H Swalwell","year":"2011","unstructured":"Swalwell H, Latimer J, Haywood RM, Birch-Machin MA (2011) Investigating the role of melanin in UVA\/UVB- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells. Free Radic Biol Med 52:626\u2013634","journal-title":"Free Radic Biol Med"},{"key":"1695_CR43","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0165-6147(98)01193-6","volume":"19","author":"C Szabo","year":"1998","unstructured":"Szabo C, Dawson VL (1998) Role of poly (ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Trends Pharmacol Sci 19:287\u2013298","journal-title":"Trends Pharmacol Sci"},{"key":"1695_CR44","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH659>3.0.CO;2-D","volume":"191","author":"DJ Tobin","year":"2000","unstructured":"Tobin DJ, Swanson NN, Pittelkow MR et al (2000) Melanocytes are not absent in lesional skin of long duration vitiligo. J Pathol 191:407\u2013416","journal-title":"J Pathol"},{"key":"1695_CR45","doi-asserted-by":"crossref","first-page":"863","DOI":"10.3892\/ijo.2013.1769","volume":"42","author":"M Tochiqi","year":"2013","unstructured":"Tochiqi M, Inoue T, Suzuki M et al (2013) Hydrogen peroxide induces cell death in human TRAIL-resistant melanoma through intracellular superoxide generation. Int J Oncol 42:863\u2013872","journal-title":"Int J Oncol"},{"key":"1695_CR46","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1089\/ars.2011.3968","volume":"15","author":"E Veal","year":"2011","unstructured":"Veal E, Day A (2011) Hydrogen peroxide as a signaling molecule. Antiox Redox Signal 15:147\u2013151","journal-title":"Antiox Redox Signal"},{"key":"1695_CR47","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1042\/BJ20040259","volume":"381","author":"CC Winterboum","year":"2004","unstructured":"Winterboum CC, Parsons-Mair HN, Gebick S, Gebicki JM, Davis MJ (2004) Requirements for superoxide dependent tyrosine hydroxyperoxide formation in peptides. Biochem J 381:241\u2013248","journal-title":"Biochem J"},{"key":"1695_CR48","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1007\/s00403-012-1277-6","volume":"304","author":"L Yao","year":"2012","unstructured":"Yao L, Hu D-N, Chen M, Li S-S (2012) Subtoxic levels hydrogen peroxide-induced expression of interleukin-6 epidermal melanocytes. Arch Dermatol Res 304:831\u2013838","journal-title":"Arch Dermatol Res"},{"key":"1695_CR49","first-page":"215","volume":"27","author":"MZ Zailaie","year":"2001","unstructured":"Zailaie MZ (2001) The rate release of leukotriene B4 is increased from skin cultured melanocytes obtained from vitiligo patients: a possible factor of melanocyte destruction in vitiligo. Arab J Lab Med 27:215\u2013223","journal-title":"Arab J Lab Med"},{"key":"1695_CR50","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/j.1365-2133.2009.09288.x","volume":"16","author":"Z Zhou","year":"2009","unstructured":"Zhou Z, Li CY, Li K et al (2009) Decreased methionine sulphoxide reductase A expression renders\u00a0melanocytes\u00a0more sensitive to oxidative stress: a possible cause for\u00a0melanocyte\u00a0loss in\u00a0vitiligo. Br J Dermatol 16:504\u2013509","journal-title":"Br J Dermatol"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-016-1695-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00403-016-1695-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-016-1695-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T21:01:57Z","timestamp":1568494917000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00403-016-1695-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,25]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["1695"],"URL":"https:\/\/doi.org\/10.1007\/s00403-016-1695-y","relation":{},"ISSN":["0340-3696","1432-069X"],"issn-type":[{"value":"0340-3696","type":"print"},{"value":"1432-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,25]]}}}