{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:20:14Z","timestamp":1790742014081,"version":"4.1.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T00:00:00Z","timestamp":1497916800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1007\/s00403-017-1752-1","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T06:20:56Z","timestamp":1497939656000},"page":"557-565","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The microRNA effector RNA-induced silencing complex in hidradenitis suppurativa: a significant dysregulation within active inflammatory lesions"],"prefix":"10.1007","volume":"309","author":[{"given":"S.","family":"Hessam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Skrygan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk G.","family":"Bechara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,20]]},"reference":[{"key":"1752_CR1","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1210\/en.2008-0984","volume":"150","author":"BD Adams","year":"2009","unstructured":"Adams BD, Claffey KP, White BA (2009) Argonaute-2 expression is regulated by epidermal growth factor receptor and mitogen-activated protein kinase signaling and correlates with a transformed phenotype in breast cancer cells. Endocrinology 150:14\u201323. doi:\n                        10.1210\/en.2008-0984","journal-title":"Endocrinology"},{"key":"1752_CR2","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.chom.2015.11.003","volume":"18","author":"LC Aguado","year":"2015","unstructured":"Aguado LC, Schmid S, Sachs D, Shim JV, Lim JK, tenOever BR (2015) microRNA function is limited to cytokine control in the acute response to virus infection. Cell Host Microbe 18:714\u2013722. doi:\n                        10.1016\/j.chom.2015.11.003","journal-title":"Cell Host Microbe"},{"key":"1752_CR3","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","volume":"136","author":"DP Bartel","year":"2009","unstructured":"Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215\u2013233. doi:\n                        10.1016\/j.cell.2009.01.002","journal-title":"Cell"},{"key":"1752_CR4","doi-asserted-by":"publisher","first-page":"393","DOI":"10.5021\/ad.2012.24.4.393","volume":"24","author":"FG Bechara","year":"2012","unstructured":"Bechara FG, Sand M, Skrygan M, Kreuter A, Altmeyer P, Gambichler T (2012) Acne inversa: evaluating antimicrobial peptides and proteins. Ann Dermatol 24:393\u2013397. doi:\n                        10.5021\/ad.2012.24.4.393","journal-title":"Ann Dermatol"},{"key":"1752_CR5","doi-asserted-by":"publisher","first-page":"19982","DOI":"10.1074\/jbc.M111.240077","volume":"286","author":"MA Blanco","year":"2011","unstructured":"Blanco MA, Ale\u010dkovi\u0107 M, Hua Y, Li T, Wei Y, Xu Z, Cristea IM, Kang Y (2011) Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions. J Biol Chem 286:19982\u201319992. doi:\n                        10.1074\/jbc.M111.240077","journal-title":"J Biol Chem"},{"key":"1752_CR6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1261\/rna.5167604","volume":"10","author":"MT Bohnsack","year":"2004","unstructured":"Bohnsack MT, Czaplinski K, Gorlich D (2004) Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA N Y N 10:185\u2013191","journal-title":"RNA N Y N"},{"key":"1752_CR7","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1084\/jem.20111717","volume":"210","author":"Y Bronevetsky","year":"2013","unstructured":"Bronevetsky Y, Villarino AV, Eisley CJ, Barbeau R, Barczak AJ, Heinz GA, Kremmer E, Heissmeyer V, McManus MT, Erle DJ, Rao A, Ansel KM (2013) T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire. J Exp Med 210:417\u2013432. doi:\n                        10.1084\/jem.20111717","journal-title":"J Exp Med"},{"key":"1752_CR8","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","volume":"55","author":"SA Bustin","year":"2009","unstructured":"Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55:611\u2013622. doi:\n                        10.1373\/clinchem.2008.112797","journal-title":"Clin Chem"},{"key":"1752_CR9","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1038\/nature03868","volume":"436","author":"TP Chendrimada","year":"2005","unstructured":"Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R (2005) TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436:740\u2013744. doi:\n                        10.1038\/nature03868","journal-title":"Nature"},{"key":"1752_CR10","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1084\/jem.20081219","volume":"205","author":"MMW Chong","year":"2008","unstructured":"Chong MMW, Rasmussen JP, Rudensky AY, Rundensky AY, Littman DR (2008) The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. J Exp Med 205:2005\u20132017. doi:\n                        10.1084\/jem.20081219","journal-title":"J Exp Med"},{"key":"1752_CR11","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1016\/j.cell.2007.10.032","volume":"131","author":"S Diederichs","year":"2007","unstructured":"Diederichs S, Haber DA (2007) Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 131:1097\u20131108. doi:\n                        10.1016\/j.cell.2007.10.032","journal-title":"Cell"},{"key":"1752_CR12","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1001\/archdermatol.2011.315","volume":"148","author":"B Dr\u00e9no","year":"2012","unstructured":"Dr\u00e9no B, Khammari A, Brocard A, Moyse D, Blouin E, Guillet G, L\u00e9onard F, Knol A-C (2012) Hidradenitis suppurativa: the role of deficient cutaneous innate immunity. Arch Dermatol 148:182\u2013186. doi:\n                        10.1001\/archdermatol.2011.315","journal-title":"Arch Dermatol"},{"key":"1752_CR13","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1038\/ni.1798","volume":"10","author":"C Du","year":"2009","unstructured":"Du C, Liu C, Kang J, Zhao G, Ye Z, Huang S, Li Z, Wu Z, Pei G (2009) MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol 10:1252\u20131259. doi:\n                        10.1038\/ni.1798","journal-title":"Nat Immunol"},{"key":"1752_CR14","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1189\/jlb.0211074","volume":"90","author":"M Gazzar El","year":"2011","unstructured":"El Gazzar M, Church A, Liu T, McCall CE (2011) MicroRNA-146a regulates both transcription silencing and translation disruption of TNF- during TLR4-induced gene reprogramming. J Leukoc Biol 90:509\u2013519. doi:\n                        10.1189\/jlb.0211074","journal-title":"J Leukoc Biol"},{"key":"1752_CR15","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1111\/j.1365-2133.2011.10765.x","volume":"166","author":"VU Emelianov","year":"2012","unstructured":"Emelianov VU, Bechara FG, Gl\u00e4ser R, Langan EA, Taungjaruwinai WM, Schr\u00f6der JM, Meyer KC, Paus R (2012) Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa\/acne inversa. Br J Dermatol 166:1023\u20131034. doi:\n                        10.1111\/j.1365-2133.2011.10765.x","journal-title":"Br J Dermatol"},{"key":"1752_CR16","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1111\/j.1365-2133.2006.07556.x","volume":"156","author":"EJ Giamarellos-Bourboulis","year":"2007","unstructured":"Giamarellos-Bourboulis EJ, Antonopoulou A, Petropoulou C, Mouktaroudi M, Spyridaki E, Baziaka F, Pelekanou A, Giamarellou H, Stavrianeas NG (2007) Altered innate and adaptive immune responses in patients with hidradenitis suppurativa. Br J Dermatol 156:51\u201356. doi:\n                        10.1111\/j.1365-2133.2006.07556.x","journal-title":"Br J Dermatol"},{"key":"1752_CR17","doi-asserted-by":"publisher","first-page":"16082","DOI":"10.1038\/nrdp.2016.82","volume":"2","author":"JE Greb","year":"2016","unstructured":"Greb JE, Goldminz AM, Elder JT, Lebwohl MG, Gladman DD, Wu JJ, Mehta NN, Finlay AY, Gottlieb AB (2016) Psoriasis. Nat Rev Dis Primer 2:16082. doi:\n                        10.1038\/nrdp.2016.82","journal-title":"Nat Rev Dis Primer"},{"key":"1752_CR18","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.4161\/15476286.2014.972853","volume":"11","author":"D Guo","year":"2014","unstructured":"Guo D, Barry L, Lin SSH, Huang V, Li L-C (2014) RNAa in action: from the exception to the norm. RNA Biol 11:1221\u20131225. doi:\n                        10.4161\/15476286.2014.972853","journal-title":"RNA Biol"},{"key":"1752_CR19","doi-asserted-by":"publisher","first-page":"3016","DOI":"10.1101\/gad.1262504","volume":"18","author":"J Han","year":"2004","unstructured":"Han J, Lee Y, Yeom K-H, Kim Y-K, Jin H, Kim VN (2004) The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18:3016\u20133027. doi:\n                        10.1101\/gad.1262504","journal-title":"Genes Dev"},{"key":"1752_CR20","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1038\/ni1274","volume":"6","author":"J Han","year":"2005","unstructured":"Han J, Ulevitch RJ (2005) Limiting inflammatory responses during activation of innate immunity. Nat Immunol 6:1198\u20131205. doi:\n                        10.1038\/ni1274","journal-title":"Nat Immunol"},{"key":"1752_CR21","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/j.jaad.2015.08.052","volume":"73","author":"S Hessam","year":"2015","unstructured":"Hessam S, Sand M, Gambichler T, Bechara FG (2015) Correlation of inflammatory serum markers with disease severity in patients with hidradenitis suppurativa (HS). J Am Acad Dermatol 73:998\u20131005. doi:\n                        10.1016\/j.jaad.2015.08.052","journal-title":"J Am Acad Dermatol"},{"key":"1752_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2016.02.009","author":"S Hessam","year":"2016","unstructured":"Hessam S, Sand M, Skrygan M, Gambichler T, Bechara FG (2016) Inflammation induced changes in the expression levels of components of the microRNA maturation machinery Drosha, Dicer, Drosha co-factor DGRC8 and Exportin-5 in inflammatory lesions of hidradenitis suppurativa patients. J Dermatol Sci. doi:\n                        10.1016\/j.jdermsci.2016.02.009","journal-title":"J Dermatol Sci"},{"key":"1752_CR23","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1002\/wrna.1272","volume":"6","author":"A Heyam","year":"2015","unstructured":"Heyam A, Lagos D, Plevin M (2015) Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs. Wiley Interdiscip Rev RNA 6:271\u2013289. doi:\n                        10.1002\/wrna.1272","journal-title":"Wiley Interdiscip Rev RNA"},{"key":"1752_CR24","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1016\/j.jaad.2011.07.020","volume":"66","author":"SC Hofmann","year":"2012","unstructured":"Hofmann SC, Saborowski V, Lange S, Kern WV, Bruckner-Tuderman L, Rieg S (2012) Expression of innate defense antimicrobial peptides in hidradenitis suppurativa. J Am Acad Dermatol 66:966\u2013974. doi:\n                        10.1016\/j.jaad.2011.07.020","journal-title":"J Am Acad Dermatol"},{"key":"1752_CR25","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1038\/nrm2321","volume":"9","author":"G Hutvagner","year":"2008","unstructured":"Hutvagner G, Simard MJ (2008) Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol 9:22\u201332. doi:\n                        10.1038\/nrm2321","journal-title":"Nat Rev Mol Cell Biol"},{"key":"1752_CR26","doi-asserted-by":"publisher","first-page":"465","DOI":"10.3892\/ijo.2014.2766","volume":"46","author":"N Jariwala","year":"2015","unstructured":"Jariwala N, Rajasekaran D, Srivastava J, Gredler R, Akiel MA, Robertson CL, Emdad L, Fisher PB, Sarkar D (2015) Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (review). Int J Oncol 46:465\u2013473. doi:\n                        10.3892\/ijo.2014.2766","journal-title":"Int J Oncol"},{"key":"1752_CR27","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1758-907X-2-5","volume":"2","author":"M Johnston","year":"2011","unstructured":"Johnston M, Hutvagner G (2011) Posttranslational modification of Argonautes and their role in small RNA-mediated gene regulation. Silence 2:5. doi:\n                        10.1186\/1758-907X-2-5","journal-title":"Silence"},{"key":"1752_CR28","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1111\/bjd.14075","volume":"173","author":"G Kelly","year":"2015","unstructured":"Kelly G, Hughes R, McGarry T, van den Born M, Adamzik K, Fitzgerald R, Lawlor C, Tobin AM, Sweeney CM, Kirby B (2015) Dysregulated cytokine expression in lesional and nonlesional skin in hidradenitis suppurativa. Br J Dermatol 173:1431\u20131439. doi:\n                        10.1111\/bjd.14075","journal-title":"Br J Dermatol"},{"key":"1752_CR29","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1007\/s00105-015-3616-y","volume":"66","author":"J Kirschke","year":"2015","unstructured":"Kirschke J, Hessam S, Bechara FG (2015) Hidradenitis suppurativa\/acne inversa: an update. Hautarzt 66:413\u2013422. doi:\n                        10.1007\/s00105-015-3616-y","journal-title":"Hautarzt"},{"key":"1752_CR30","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1038\/nrg2843","volume":"11","author":"J Krol","year":"2010","unstructured":"Krol J, Loedige I, Filipowicz W (2010) The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11:597\u2013610. doi:\n                        10.1038\/nrg2843","journal-title":"Nat Rev Genet"},{"key":"1752_CR31","doi-asserted-by":"publisher","unstructured":"Kurzen H, Kurokawa I, Jemec GBE, Emtestam L, Sellheyer K, Giamarellos-Bourboulis EJ, Nagy I, Bechara FG, Sartorius K, Lapins J, Krahl D, Altmeyer P, Revuz J, Zouboulis CC (2008) What causes hidradenitis suppurativa? Exp Dermatol 17:455\u2013456\u2013472. doi: \n                        10.1111\/j.1600-0625.2008.00712_1.x","DOI":"10.1111\/j.1600-0625.2008.00712_1.x"},{"key":"1752_CR32","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/j.1600-0625.2009.00915.x","volume":"19","author":"M Laffert von","year":"2010","unstructured":"von Laffert M, Helmbold P, Wohlrab J, Fiedler E, Stadie V, Marsch WC (2010) Hidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermis. Exp Dermatol 19:533\u2013537. doi:\n                        10.1111\/j.1600-0625.2009.00915.x","journal-title":"Exp Dermatol"},{"key":"1752_CR33","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1016\/j.cub.2004.11.001","volume":"14","author":"M Landthaler","year":"2004","unstructured":"Landthaler M, Yalcin A, Tuschl T (2004) The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol CB 14:2162\u20132167. doi:\n                        10.1016\/j.cub.2004.11.001","journal-title":"Curr Biol CB"},{"key":"1752_CR34","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1080\/000155501750208146","volume":"81","author":"J Lapins","year":"2001","unstructured":"Lapins J, Asman B, Gustafsson A, Bergstr\u00f6m K, Emtestam L (2001) Neutrophil-related host response in hidradenitis suppurativa: a pilot study in patients with inactive disease. Acta Derm Venereol 81:96\u201399","journal-title":"Acta Derm Venereol"},{"key":"1752_CR35","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/nature01957","volume":"425","author":"Y Lee","year":"2003","unstructured":"Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, R\u00e5dmark O, Kim S, Kim VN (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415\u2013419. doi:\n                        10.1038\/nature01957","journal-title":"Nature"},{"key":"1752_CR36","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1038\/sj.emboj.7600942","volume":"25","author":"Y Lee","year":"2006","unstructured":"Lee Y, Hur I, Park S-Y, Kim Y-K, Suh MR, Kim VN (2006) The role of PACT in the RNA silencing pathway. EMBO J 25:522\u2013532. doi:\n                        10.1038\/sj.emboj.7600942","journal-title":"EMBO J"},{"key":"1752_CR37","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/bjd.14214","volume":"174","author":"AL Lima","year":"2016","unstructured":"Lima AL, Karl I, Giner T, Poppe H, Schmidt M, Presser D, Goebeler M, Bauer B (2016) Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa. Br J Dermatol 174:514\u2013521. doi:\n                        10.1111\/bjd.14214","journal-title":"Br J Dermatol"},{"key":"1752_CR38","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods San Diego Calif 25:402\u2013408. doi:\n                        10.1006\/meth.2001.1262","journal-title":"Methods San Diego Calif"},{"key":"1752_CR39","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1101\/gad.2038811","volume":"25","author":"E Lund","year":"2011","unstructured":"Lund E, Sheets MD, Imboden SB, Dahlberg JE (2011) Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis. Genes Dev 25:1121\u20131131. doi:\n                        10.1101\/gad.2038811","journal-title":"Genes Dev"},{"key":"1752_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4137\/BIC.S37333","volume":"8","author":"J Ma","year":"2016","unstructured":"Ma J, Li N, Lin Y, Gupta C, Jiang F (2016) Circulating neutrophil microRNAs as biomarkers for the detection of lung cancer. Biomark Cancer 8:1\u20137. doi:\n                        10.4137\/BIC.S37333","journal-title":"Biomark Cancer"},{"key":"1752_CR41","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1038\/ni1209-1229","volume":"10","author":"AJ Martin","year":"2009","unstructured":"Martin AJ, Zhou L, Miller SD (2009) MicroRNA-managing the TH-17 inflammatory response. Nat Immunol 10:1229\u20131231. doi:\n                        10.1038\/ni1209-1229","journal-title":"Nat Immunol"},{"key":"1752_CR42","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1002\/art.38269","volume":"66","author":"K Murata","year":"2014","unstructured":"Murata K, Yoshitomi H, Furu M, Ishikawa M, Shibuya H, Ito H, Matsuda S (2014) MicroRNA-451 down-regulates neutrophil chemotaxis via p38 MAPK. Arthritis Rheumatol Hoboken NJ 66:549\u2013559. doi:\n                        10.1002\/art.38269","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"1752_CR43","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1016\/j.cell.2010.02.029","volume":"140","author":"C Nathan","year":"2010","unstructured":"Nathan C, Ding A (2010) Nonresolving inflammation. Cell 140:871\u2013882. doi:\n                        10.1016\/j.cell.2010.02.029","journal-title":"Cell"},{"key":"1752_CR44","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s12865-015-0134-8","volume":"16","author":"CC Pedersen","year":"2015","unstructured":"Pedersen CC, Refsgaard JC, \u00d8stergaard O, Jensen LJ, Heegaard NHH, Borregaard N, Cowland JB (2015) Impact of microRNA-130a on the neutrophil proteome. BMC Immunol 16:70. doi:\n                        10.1186\/s12865-015-0134-8","journal-title":"BMC Immunol"},{"key":"1752_CR45","doi-asserted-by":"publisher","first-page":"E3101","DOI":"10.1073\/pnas.1209100109","volume":"109","author":"M Rossato","year":"2012","unstructured":"Rossato M, Curtale G, Tamassia N, Castellucci M, Mori L, Gasperini S, Mariotti B, De Luca M, Mirolo M, Cassatella MA, Locati M, Bazzoni F (2012) IL-10-induced microRNA-187 negatively regulates TNF-\u03b1, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc Natl Acad Sci USA 109:E3101\u2013E3110. doi:\n                        10.1073\/pnas.1209100109","journal-title":"Proc Natl Acad Sci USA"},{"key":"1752_CR46","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-1-62703-703-7_1","volume":"1095","author":"M Sand","year":"2014","unstructured":"Sand M (2014) The pathway of miRNA maturation. Methods Mol Biol Clifton NJ 1095:3\u201310. doi:\n                        10.1007\/978-1-62703-703-7_1","journal-title":"Methods Mol Biol Clifton NJ"},{"key":"1752_CR47","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.jdermsci.2008.10.004","volume":"53","author":"M Sand","year":"2009","unstructured":"Sand M, Gambichler T, Sand D, Skrygan M, Altmeyer P, Bechara FG (2009) MicroRNAs and the skin: tiny players in the body\u2019s largest organ. J Dermatol Sci 53:169\u2013175. doi:\n                        10.1016\/j.jdermsci.2008.10.004","journal-title":"J Dermatol Sci"},{"key":"1752_CR48","doi-asserted-by":"publisher","first-page":"253","DOI":"10.3233\/cbm-2012-0274","volume":"11","author":"M Sand","year":"2012","unstructured":"Sand M, Sand D, Altmeyer P, Bechara FG (2012) MicroRNA in non-melanoma skin cancer. Cancer Biomark 11:253\u2013257. doi:\n                        10.3233\/cbm-2012-0274","journal-title":"Cancer Biomark"},{"key":"1752_CR49","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/978-1-62703-703-7_4","volume":"1095","author":"M Sand","year":"2014","unstructured":"Sand M, Skrygan M (2014) Expression profiling of components of the miRNA maturation machinery. Methods Mol Biol Clifton NJ 1095:61\u201371. doi:\n                        10.1007\/978-1-62703-703-7_4","journal-title":"Methods Mol Biol Clifton NJ"},{"key":"1752_CR50","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/s00441-012-1446-0","volume":"350","author":"M Sand","year":"2012","unstructured":"Sand M, Skrygan M, Georgas D, Sand D, Gambichler T, Altmeyer P, Bechara FG (2012) The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi. Cell Tissue Res 350:119\u2013126. doi:\n                        10.1007\/s00441-012-1446-0","journal-title":"Cell Tissue Res"},{"key":"1752_CR51","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/j.jaad.2010.07.010","volume":"65","author":"C Schlapbach","year":"2011","unstructured":"Schlapbach C, H\u00e4nni T, Yawalkar N, Hunger RE (2011) Expression of the IL-23\/Th17 pathway in lesions of hidradenitis suppurativa. J Am Acad Dermatol 65:790\u2013798. doi:\n                        10.1016\/j.jaad.2010.07.010","journal-title":"J Am Acad Dermatol"},{"key":"1752_CR52","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1111\/j.1365-4632.2004.02536.x","volume":"44","author":"K Sellheyer","year":"2005","unstructured":"Sellheyer K, Krahl D (2005) \u201cHidradenitis suppurativa\u201d is acne inversa! An appeal to (finally) abandon a misnomer. Int J Dermatol 44:535\u2013540. doi:\n                        10.1111\/j.1365-4632.2004.02536.x","journal-title":"Int J Dermatol"},{"key":"1752_CR53","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3389\/fgene.2013.00008","volume":"4","author":"A Sethi","year":"2013","unstructured":"Sethi A, Kulkarni N, Sonar S, Lal G (2013) Role of miRNAs in CD4 T cell plasticity during inflammation and tolerance. Front Genet 4:8. doi:\n                        10.3389\/fgene.2013.00008","journal-title":"Front Genet"},{"key":"1752_CR54","doi-asserted-by":"publisher","first-page":"535","DOI":"10.3109\/08830180903208303","volume":"28","author":"E Sonkoly","year":"2009","unstructured":"Sonkoly E, Pivarcsi A (2009) MicroRNAs in inflammation. Int Rev Immunol 28:535\u2013561. doi:\n                        10.3109\/08830180903208303","journal-title":"Int Rev Immunol"},{"key":"1752_CR55","doi-asserted-by":"publisher","first-page":"e610","DOI":"10.1371\/journal.pone.0000610","volume":"2","author":"E Sonkoly","year":"2007","unstructured":"Sonkoly E, Wei T, Janson PCJ, S\u00e4\u00e4f A, Lundeberg L, Tengvall-Linder M, Norstedt G, Alenius H, Homey B, Scheynius A, St\u00e5hle M, Pivarcsi A (2007) MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One 2:e610. doi:\n                        10.1371\/journal.pone.0000610","journal-title":"PLoS One"},{"key":"1752_CR56","doi-asserted-by":"publisher","first-page":"e15810","DOI":"10.1371\/journal.pone.0015810","volume":"6","author":"JR Ward","year":"2011","unstructured":"Ward JR, Heath PR, Catto JW, Whyte MKB, Milo M, Renshaw SA (2011) Regulation of neutrophil senescence by microRNAs. PLoS One 6:e15810. doi:\n                        10.1371\/journal.pone.0015810","journal-title":"PLoS One"},{"key":"1752_CR57","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.4161\/rna.8.6.17665","volume":"8","author":"J Winter","year":"2011","unstructured":"Winter J, Diederichs S (2011) Argonaute proteins regulate microRNA stability: increased microRNA abundance by Argonaute proteins is due to microRNA stabilization. RNA Biol 8:1149\u20131157. doi:\n                        10.4161\/rna.8.6.17665","journal-title":"RNA Biol"},{"key":"1752_CR58","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1002\/hep.24216","volume":"53","author":"BK Yoo","year":"2011","unstructured":"Yoo BK, Santhekadur PK, Gredler R, Chen D, Emdad L, Bhutia S, Pannell L, Fisher PB, Sarkar D (2011) Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma. Hepatol Baltim Md 53:1538\u20131548. doi:\n                        10.1002\/hep.24216","journal-title":"Hepatol Baltim Md"},{"key":"1752_CR59","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1002\/jcb.23340","volume":"113","author":"K Yoshida","year":"2012","unstructured":"Yoshida K, Okamura H, Hoshino Y, Shono M, Yoshioka M, Hinode D, Yoshida H (2012) Interaction between PKR and PACT mediated by LPS-inducible NF-\u03baB in human gingival cells. J Cell Biochem 113:165\u2013173. doi:\n                        10.1002\/jcb.23340","journal-title":"J Cell Biochem"},{"key":"1752_CR60","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1111\/j.1600-0625.2012.01552.x","volume":"21","author":"HH Zee van der","year":"2012","unstructured":"van der Zee HH, Laman JD, Boer J, Prens EP (2012) Hidradenitis suppurativa: viewpoint on clinical phenotyping, pathogenesis and novel treatments. Exp Dermatol 21:735\u2013739. doi:\n                        10.1111\/j.1600-0625.2012.01552.x","journal-title":"Exp Dermatol"},{"key":"1752_CR61","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1111\/j.1365-2133.2011.10254.x","volume":"164","author":"HH Zee van der","year":"2011","unstructured":"van der Zee HH, de Ruiter L, van den Broecke DG, Dik WA, Laman JD, Prens EP (2011) Elevated levels of tumour necrosis factor (TNF)-\u03b1, interleukin (IL)-1\u03b2 and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-\u03b1 and IL-1\u03b2. Br J Dermatol 164:1292\u20131298. doi:\n                        10.1111\/j.1365-2133.2011.10254.x","journal-title":"Br J Dermatol"},{"key":"1752_CR62","doi-asserted-by":"publisher","first-page":"2621","DOI":"10.1002\/lary.23517","volume":"122","author":"Y-N Zhang","year":"2012","unstructured":"Zhang Y-N, Cao P-P, Zhang X-H, Lu X, Liu Z (2012) Expression of microRNA machinery proteins in different types of chronic rhinosinusitis. Laryngoscope 122:2621\u20132627. doi:\n                        10.1002\/lary.23517","journal-title":"Laryngoscope"},{"key":"1752_CR63","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1038\/cmi.2011.27","volume":"8","author":"L Zhou","year":"2011","unstructured":"Zhou L, Park J-J, Zheng Q, Dong Z, Mi Q (2011) MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function. Cell Mol Immunol 8:380\u2013387. doi:\n                        10.1038\/cmi.2011.27","journal-title":"Cell Mol Immunol"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00403-017-1752-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-017-1752-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-017-1752-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T07:34:22Z","timestamp":1504078462000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00403-017-1752-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,20]]},"references-count":63,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["1752"],"URL":"https:\/\/doi.org\/10.1007\/s00403-017-1752-1","relation":{},"ISSN":["0340-3696","1432-069X"],"issn-type":[{"value":"0340-3696","type":"print"},{"value":"1432-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,20]]}}}