{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T19:53:28Z","timestamp":1776714808569,"version":"3.51.2"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T00:00:00Z","timestamp":1572998400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T00:00:00Z","timestamp":1572998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s00403-019-02005-9","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T18:03:12Z","timestamp":1573063392000},"page":"461-466","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["DNA methylation and inflammatory skin diseases"],"prefix":"10.1007","volume":"312","author":[{"given":"Joshua S.","family":"Mervis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean S.","family":"McGee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,11,6]]},"reference":[{"issue":"1","key":"2005_CR1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1093\/ije\/dyr184","volume":"41","author":"CH Waddington","year":"2012","unstructured":"Waddington CH (2012) The epigenotype. Int J Epidemiol 41(1):10\u201313","journal-title":"Int J Epidemiol"},{"issue":"3","key":"2005_CR2","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/nm.2305","volume":"17","author":"M Rodr\u00edguez-Paredes","year":"2011","unstructured":"Rodr\u00edguez-Paredes M, Esteller M (2011) Cancer epigenetics reaches mainstream oncology. Nat Med 17(3):330\u2013339","journal-title":"Nat Med"},{"issue":"7","key":"2005_CR3","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1101\/gad.1787609","volume":"23","author":"SL Berger","year":"2009","unstructured":"Berger SL, Kouzarides T, Shiekhattar R et al (2009) An operational definition of epigenetics. Genes Dev 23(7):781\u2013783","journal-title":"Genes Dev"},{"issue":"5","key":"2005_CR4","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/nrg.2016.13","volume":"17","author":"AP Feinberg","year":"2016","unstructured":"Feinberg AP, Koldobskiy MA, G\u00f6nd\u00f6r A (2016) Epigenetic modulators, modifiers and mediators in cancer aetiology and progression. Nat Rev Genet 17(5):284\u2013299","journal-title":"Nat Rev Genet"},{"issue":"1","key":"2005_CR5","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.cell.2012.06.013","volume":"150","author":"MA Dawson","year":"2012","unstructured":"Dawson MA, Kouzarides T (2012) Cancer epigenetics: from mechanism to therapy. Cell 150(1):12\u201327","journal-title":"Cell"},{"issue":"9","key":"2005_CR6","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrg.2017.33","volume":"18","author":"X Wu","year":"2017","unstructured":"Wu X, Zhang Y (2017) TET-mediated active DNA demethylation: mechanism, function and beyond. Nat Rev Genet 18(9):517\u2013534","journal-title":"Nat Rev Genet"},{"issue":"4","key":"2005_CR7","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/nrg2005","volume":"8","author":"M Esteller","year":"2007","unstructured":"Esteller M (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8(4):286\u2013298","journal-title":"Nat Rev Genet"},{"issue":"4","key":"2005_CR8","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1056\/NEJMc1805989","volume":"379","author":"Feinberg","year":"2018","unstructured":"Feinberg (2018) The key role of epigenetics in human disease. N Engl J Med 379(4):400\u2013401","journal-title":"N Engl J Med"},{"issue":"3","key":"2005_CR9","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jdermsci.2009.01.009","volume":"54","author":"Y Li","year":"2009","unstructured":"Li Y, Sawalha AH, Lu Q (2009) Aberrant DNA methylation in skin diseases. J Dermatol Sci 54(3):143\u2013149","journal-title":"J Dermatol Sci"},{"key":"2005_CR10","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/978-94-007-4525-4_27","volume":"61","author":"MK Shanmugam","year":"2013","unstructured":"Shanmugam MK, Sethi G (2013) Role of epigenetics in inflammation-associated diseases. Subcell Biochem 61:627\u2013657","journal-title":"Subcell Biochem"},{"issue":"7","key":"2005_CR11","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.tibs.2014.05.002","volume":"39","author":"A Jeltsch","year":"2014","unstructured":"Jeltsch A, Jurkowska RZ (2014) New concepts in DNA methylation. Trends Biochem Sci 39(7):310\u2013318","journal-title":"Trends Biochem Sci"},{"issue":"8","key":"2005_CR12","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nrg1655","volume":"6","author":"KD Robertson","year":"2005","unstructured":"Robertson KD (2005) DNA methylation and human disease. Nat Rev Genet 6(8):597\u2013610","journal-title":"Nat Rev Genet"},{"key":"2005_CR13","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0140-6736(14)61909-7","volume":"386","author":"WH Boehncke","year":"2015","unstructured":"Boehncke WH, Sch\u00f6n MP (2015) Psoriasis. Lancet 386:983\u2013994","journal-title":"Lancet"},{"issue":"3","key":"2005_CR14","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.clindermatol.2013.11.001","volume":"32","author":"I Grozdev","year":"2014","unstructured":"Grozdev I, Korman N, Tsankov N (2014) Psoriasis as a systemic disease. Clin Dermatol 32(3):343\u2013350","journal-title":"Clin Dermatol"},{"issue":"Suppl 2:ii1","key":"2005_CR15","first-page":"4","volume":"64","author":"DD Gladman","year":"2005","unstructured":"Gladman DD, Antoni C, Mease P et al (2005) Psoriatic arthritis: epidemiology, clinical features, course, and outcome. Ann Rheum Dis 64(Suppl 2:ii1):4\u20137","journal-title":"Ann Rheum Dis"},{"key":"2005_CR16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2013.01.010","volume":"41","author":"Q Lu","year":"2013","unstructured":"Lu Q (2013) The critical importance of epigenetics in autoimmunity. J Autoimmun 41:1\u20135","journal-title":"J Autoimmun"},{"issue":"18","key":"2005_CR17","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1007\/s00018-018-2864-2","volume":"75","author":"Z Wang","year":"2018","unstructured":"Wang Z, Long H, Chang C, Zhao M, Lu Q (2018) Crosstalk between metabolism and epigenetic modifications in autoimmune diseases: a comprehensive overview. Cell Mol Life Sci 75(18):3353\u20133369","journal-title":"Cell Mol Life Sci"},{"issue":"2","key":"2005_CR18","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1016\/j.jisp.2018.09.007","volume":"19","author":"M Zhao","year":"2018","unstructured":"Zhao M, Lu Q (2018) The aberrant epigenetic modifications in the pathogenesis of psoriasis. J Investig Dermatol Symp Proc 19(2):S81\u2013S82.","journal-title":"J Investig Dermatol Symp Proc"},{"key":"2005_CR19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jaut.2016.12.002","volume":"78","author":"RA Pollock","year":"2017","unstructured":"Pollock RA, Abji F, Gladman DD (2017) Epigenetics of psoriatic disease: A systematic review and critical appraisal. J Autoimmun. 78:29\u201338","journal-title":"J Autoimmun."},{"issue":"5","key":"2005_CR20","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/ajmg.1320420504","volume":"42","author":"H Traupe","year":"1992","unstructured":"Traupe H, van Gurp PJ, Happle R et al (1992) Psoriasis vulgaris, fetal growth, and genomic imprinting. Am J Med Genet 42(5):649\u2013654","journal-title":"Am J Med Genet"},{"key":"2005_CR21","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jaut.2017.04.005","volume":"83","author":"E Generali","year":"2017","unstructured":"Generali E, Ceribelli A, Stazi MA et al (2017) Lessons learned from twins in autoimmune and chronic inflammatory diseases. J Autoimmun 83:51\u201361","journal-title":"J Autoimmun"},{"issue":"83","key":"2005_CR22","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jaut.2017.04.003","volume":"1","author":"Z Xiang","year":"2017","unstructured":"Xiang Z, Yang Y, Chang C, Lu Q (2017) The epigenetic mechanism for discordance of autoimmunity in monozygotic twins. J Autoimmun 1(83):43\u201350","journal-title":"J Autoimmun"},{"issue":"1","key":"2005_CR23","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jdermsci.2010.07.011","volume":"60","author":"P Zhang","year":"2010","unstructured":"Zhang P, Su Y, Chen H et al (2010) Abnormal DNA methylation in skin lesions and PBMCs of patients with psoriasis vulgaris. J Dermatol Sci 60(1):40\u201342","journal-title":"J Dermatol Sci"},{"issue":"7","key":"2005_CR24","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/jhg.2015.33","volume":"60","author":"S Yooyongsatit","year":"2015","unstructured":"Yooyongsatit S, Ruchusatsawat K, Noppakun N et al (2015) Patterns and functional roles of LINE-1 and Alu methylation in the keratinocyte from patients with psoriasis vulgaris. J Hum Genet 60(7):349\u2013355","journal-title":"J Hum Genet"},{"issue":"1","key":"2005_CR25","doi-asserted-by":"crossref","first-page":"13624","DOI":"10.1038\/s41598-017-14165-7","volume":"7","author":"Y Murata","year":"2017","unstructured":"Murata Y, Bundo M, Ueda J et al (2017) DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice. Sci Rep 7(1):13624","journal-title":"Sci Rep"},{"issue":"3","key":"2005_CR26","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/jid.2011.348","volume":"132","author":"ED Roberson","year":"2012","unstructured":"Roberson ED, Liu Y, Ryan C et al (2012) A subset of methylated CpG sites differentiate psoriatic from normal skin. J Invest Dermatol. 132(3):583\u2013592","journal-title":"J Invest Dermatol."},{"issue":"5","key":"2005_CR27","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.jid.2017.11.036","volume":"138","author":"D Verma","year":"2018","unstructured":"Verma D, Ekman AK, Bivik Eding C et al (2018) Genome-wide DNA methylation profiling identifies differential methylation in uninvolved psoriatic epidermis. J Invest Dermatol 138(5):1088\u20131093","journal-title":"J Invest Dermatol"},{"key":"2005_CR28","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jaut.2013.01.001","volume":"41","author":"P Zhang","year":"2013","unstructured":"Zhang P, Zhao M, Liang G et al (2013) Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris. J Autoimmun 41:17\u201324","journal-title":"J Autoimmun"},{"issue":"4","key":"2005_CR29","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.jid.2015.12.029","volume":"136","author":"F Zhou","year":"2016","unstructured":"Zhou F, Wang W, Shen C et al (2016) Epigenome-wide association analysis identified nine skin DNA methylation loci for psoriasis. J Invest Dermatol 136(4):779\u2013787","journal-title":"J Invest Dermatol"},{"issue":"3","key":"2005_CR30","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.jdermsci.2018.06.001","volume":"91","author":"L Tang","year":"2018","unstructured":"Tang L, Cheng Y, Zhu C et al (2018) Integrative methylome and transcriptome analysis to dissect key biological pathways for psoriasis in Chinese Han population. J Dermatol Sci 91(3):285\u2013291","journal-title":"J Dermatol Sci"},{"issue":"5","key":"2005_CR31","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/j.1365-2133.2008.08505.x","volume":"158","author":"M Chen","year":"2008","unstructured":"Chen M, Chen ZQ, Cui PG et al (2008) The methylation pattern of p16INK4a gene promoter in psoriatic epidermis and its clinical significance. Br J Dermatol 158(5):987\u2013993","journal-title":"Br J Dermatol"},{"issue":"1","key":"2005_CR32","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jdermsci.2016.04.003","volume":"83","author":"M Chen","year":"2016","unstructured":"Chen M, Wang Y, Yao X et al (2016) Hypermethylation of HLA-C may be an epigenetic marker in psoriasis. J Dermatol Sci. 83(1):10\u201316","journal-title":"J Dermatol Sci."},{"issue":"1","key":"2005_CR33","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s13148-018-0541-9","volume":"10","author":"A Chandra","year":"2018","unstructured":"Chandra A, Senapati S, Roy S et al (2018) Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis. Clin Epigenetics 10(1):108","journal-title":"Clin Epigenetics"},{"issue":"1","key":"2005_CR34","doi-asserted-by":"crossref","first-page":"e1002454","DOI":"10.1371\/journal.pgen.1002454","volume":"8","author":"K Gervin","year":"2012","unstructured":"Gervin K, Vigeland MD, Mattingsdal M et al (2012) DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes. PLoS Genet 8(1):e1002454","journal-title":"PLoS Genet"},{"issue":"1","key":"2005_CR35","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.bbrc.2012.04.128","volume":"422","author":"J Han","year":"2012","unstructured":"Han J, Park SG, Bae JB et al (2012) The characteristics of genome-wide DNA methylation in na\u00efve CD4+ T cells of patients with psoriasis or atopic dermatitis. Biochem Biophys Res Commun 422(1):157\u2013163","journal-title":"Biochem Biophys Res Commun"},{"issue":"3","key":"2005_CR36","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s00403-013-1432-8","volume":"306","author":"GT Park","year":"2014","unstructured":"Park GT, Han J, Park SG et al (2014) DNA methylation analysis of CD4+ T cells in patients with psoriasis. Arch Dermatol Res. 306(3):259\u2013268","journal-title":"Arch Dermatol Res."},{"issue":"8","key":"2005_CR37","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1038\/jid.2015.128","volume":"135","author":"X Gu","year":"2015","unstructured":"Gu X, Nylander E, Coates PJ et al (2015) Correlation between reversal of DNA methylation and clinical symptoms in psoriatic epidermis following narrow-band UVB phototherapy. J Invest Dermatol 135(8):2077\u20132083","journal-title":"J Invest Dermatol"},{"issue":"14","key":"2005_CR38","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1056\/NEJMra074081","volume":"358","author":"T Bieber","year":"2008","unstructured":"Bieber T (2008) Atopic dermatitis. N Engl J Med 358(14):1483\u20131494","journal-title":"N Engl J Med"},{"issue":"3","key":"2005_CR39","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s12016-015-8508-5","volume":"51","author":"Y Liang","year":"2016","unstructured":"Liang Y, Chang C, Lu Q (2016) The genetics and epigenetics of atopic dermatitis\u2014filaggrin and other polymorphisms. Clin Rev Allergy Immunol 51(3):315\u2013328","journal-title":"Clin Rev Allergy Immunol"},{"issue":"9","key":"2005_CR40","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1111\/all.12882","volume":"71","author":"GA Lockett","year":"2016","unstructured":"Lockett GA, Soto-Ram\u00edrez N, Ray MA et al (2016) Association of season of birth with DNA methylation and allergic disease. Allergy 71(9):1314\u20131324","journal-title":"Allergy"},{"issue":"5","key":"2005_CR41","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/cea.12108","volume":"43","author":"IJ Wang","year":"2013","unstructured":"Wang IJ, Chen SL, Lu TP et al (2013) Prenatal smoke exposure, DNA methylation, and childhood atopic dermatitis. Clin Exp Allergy 43(5):535\u2013543","journal-title":"Clin Exp Allergy"},{"issue":"2","key":"2005_CR42","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jdermsci.2015.08.004","volume":"80","author":"CM Nguyen","year":"2015","unstructured":"Nguyen CM, Liao W (2015) Genomic imprinting in psoriasis and atopic dermatitis: a review. J Dermatol Sci 80(2):89\u201393","journal-title":"J Dermatol Sci"},{"issue":"5","key":"2005_CR43","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00403-006-0682-0","volume":"298","author":"T Nakamura","year":"2006","unstructured":"Nakamura T, Sekigawa I, Ogasawara H et al (2006) Expression of DNMT-1 in patients with atopic dermatitis. Arch Dermatol Res 298(5):253\u2013256","journal-title":"Arch Dermatol Res"},{"issue":"6 Suppl","key":"2005_CR44","doi-asserted-by":"crossref","first-page":"S128","DOI":"10.1016\/j.jaci.2003.09.032","volume":"112","author":"N Novak","year":"2003","unstructured":"Novak N, Bieber T, Leung DY (2003) Immune mechanisms leading to atopic dermatitis. J Allergy Clin Immunol. 112(6 Suppl):S128\u2013S139","journal-title":"J Allergy Clin Immunol."},{"issue":"1","key":"2005_CR45","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/ced.12206","volume":"39","author":"Y Luo","year":"2014","unstructured":"Luo Y, Zhou B, Zhao M et al (2014) Promoter demethylation contributes to TSLP overexpression in skin lesions of patients with atopic dermatitis. Clin Exp Dermatol 39(1):48\u201353","journal-title":"Clin Exp Dermatol"},{"issue":"3","key":"2005_CR46","doi-asserted-by":"crossref","first-page":"e420","DOI":"10.1111\/jdv.12000","volume":"27","author":"AH Ziyab","year":"2013","unstructured":"Ziyab AH, Karmaus W, Holloway JW et al (2013) DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants. J Eur Acad Dermatol Venereol 27(3):e420\u2013e423","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"7","key":"2005_CR47","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1038\/jid.2014.87","volume":"134","author":"E Rodr\u00edguez","year":"2014","unstructured":"Rodr\u00edguez E, Baurecht H, Wahn AF et al (2014) An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis. J Invest Dermatol 134(7):1873\u20131883","journal-title":"J Invest Dermatol"},{"issue":"8","key":"2005_CR48","doi-asserted-by":"crossref","first-page":"E1490","DOI":"10.1073\/pnas.1616420114","volume":"114","author":"C Leoni","year":"2017","unstructured":"Leoni C, Montagner S, Rinaldi A et al (2017) DNMT3a restrains mast cell inflammatory responses. Proc Natl Acad Sci USA 114(8):E1490\u2013E1499","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"2005_CR49","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/ejh.12537","volume":"95","author":"C Leoni","year":"2015","unstructured":"Leoni C, Montagner S, Deho' L et al (2015) Reduced DNA methylation and hydroxymethylation in patients with systemic mastocytosis. Eur J Haematol 95(6):566\u2013575","journal-title":"Eur J Haematol"},{"issue":"2","key":"2005_CR50","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.gene.2015.03.075","volume":"564","author":"A Shukla","year":"2015","unstructured":"Shukla A, Sehgal M, Singh TR (2015) Hydroxymethylation and its potential implication in DNA repair system: a review and future perspectives. Gene 564(2):109\u2013118","journal-title":"Gene"},{"issue":"2\u20133","key":"2005_CR51","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000478043","volume":"233","author":"S Hessam","year":"2017","unstructured":"Hessam S, Sand M, Lang K et al (2017) Altered global 5-hydroxymethylation status in hidradenitis suppurativa: support for an epigenetic background. Dermatology 233(2\u20133):129\u2013135","journal-title":"Dermatology"},{"issue":"1","key":"2005_CR52","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/jop.12645","volume":"47","author":"AF Cruz","year":"2018","unstructured":"Cruz AF, de Resende RG, de Lacerda JCT et al (2018) DNA methylation patterns of genes related to immune response in the different clinical forms of oral lichen planus. J Oral Pathol Med. 47(1):91\u201395","journal-title":"J Oral Pathol Med."},{"issue":"1","key":"2005_CR53","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1080\/09546634.2018.1473550","volume":"30","author":"JS Mervis","year":"2019","unstructured":"Mervis JS, McGee JS (2019) Epigenetic therapy and dermatologic disease: moving beyond CTCL. J Dermatolog Treat 30(1):68\u201373","journal-title":"J Dermatolog Treat"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-019-02005-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00403-019-02005-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-019-02005-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:26:31Z","timestamp":1604535991000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00403-019-02005-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,6]]},"references-count":53,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["2005"],"URL":"https:\/\/doi.org\/10.1007\/s00403-019-02005-9","relation":{},"ISSN":["0340-3696","1432-069X"],"issn-type":[{"value":"0340-3696","type":"print"},{"value":"1432-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,6]]},"assertion":[{"value":"31 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 August 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 November 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors have no conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent not required for this work.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}