{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:05:57Z","timestamp":1740107157404,"version":"3.37.3"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"DOI":"10.1007\/s00403-022-02518-w","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T11:05:50Z","timestamp":1672225550000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preparation and evaluation of chitosan skin patches containing mesoporous silica nanoparticles loaded by doxycycline on skin wound healing"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4802-8534","authenticated-orcid":false,"given":"Pegah","family":"Khosravian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0975-2295","authenticated-orcid":false,"given":"Moosa","family":"Javdani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Razieh","family":"Noorbakhnia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Moghtadaei-Khorasgani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7297-5008","authenticated-orcid":false,"given":"Abolfazl","family":"Barzegar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"issue":"8","key":"2518_CR1","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1002\/jps.21210","volume":"97","author":"JS Boateng","year":"2008","unstructured":"Boateng JS, Matthews KH, Stevens HN, Eccleston GM (2008) Wound healing dressings and drug delivery systems: a review. J Pharm Sci 97(8):2892\u20132923. https:\/\/doi.org\/10.1002\/jps.21210","journal-title":"J Pharm Sci"},{"key":"2518_CR2","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0168-3659(94)90134-1","volume":"29","author":"K Sugibayashi","year":"1994","unstructured":"Sugibayashi K, Morimoto Y (1994) Polymers for transdermal drug delivery systems. J Control Release 29:177\u2013185. https:\/\/doi.org\/10.1016\/0168-3659(94)90134-1","journal-title":"J Control Release"},{"key":"2518_CR3","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/S1387-2656(08)70012-7","volume":"2","author":"S Hirano","year":"1996","unstructured":"Hirano S (1996) Chitin biotechnology applications. Biotechnol Annu Rev 2:237\u2013258. https:\/\/doi.org\/10.1016\/S1387-2656(08)70012-7","journal-title":"Biotechnol Annu Rev"},{"issue":"2","key":"2518_CR4","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/0142-9612(95)98278-M","volume":"16","author":"D Thacharodi","year":"1995","unstructured":"Thacharodi D, Rao KP (1995) Development and in vitro evaluation of chitosan-based transdermal drug delivery systems for the controlled delivery of propranolol hydrochloride. Biomaterials 16(2):145\u2013148. https:\/\/doi.org\/10.1016\/0142-9612(95)98278-M","journal-title":"Biomaterials"},{"issue":"7","key":"2518_CR5","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S0142-9612(00)00231-3","volume":"22","author":"I Van der Lubben","year":"2001","unstructured":"Van der Lubben I, Verhoef J, Van Aelst A, Borchard G, Junginger H (2001) Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer\u2019s patches. Biomaterials 22(7):687\u2013694. https:\/\/doi.org\/10.1016\/S0142-9612(00)00231-3","journal-title":"Biomaterials"},{"issue":"8","key":"2518_CR6","doi-asserted-by":"publisher","first-page":"779","DOI":"10.3109\/03639049809082726","volume":"24","author":"I Genta","year":"1998","unstructured":"Genta I, Perugini P, Pavanetto F (1998) Different molecular weight chitosan microspheres: influence on drug loading and drug release. Drug Dev Ind Pharm 24(8):779\u2013784. https:\/\/doi.org\/10.3109\/03639049809082726","journal-title":"Drug Dev Ind Pharm"},{"issue":"1","key":"2518_CR7","first-page":"77","volume":"10","author":"Y Ohya","year":"2000","unstructured":"Ohya Y, Cai R, Nishizawa H, Hara K, Ouchi T (2000) Preparation of PEG-grafted chitosan nanoparticles as peptide drug carriers. STP Pharma Sci 10(1):77\u201382","journal-title":"STP Pharma Sci"},{"key":"2518_CR8","doi-asserted-by":"publisher","unstructured":"Kristl J, \u0160mid-Korbar J, \u0160truc E, Schara M, Rupprecht H. Hydrocolloids and gels of chitosan as drug carriers. Int J Pharm 99(1):13\u201319. https:\/\/doi.org\/10.1016\/0378-5173(93)90317-9","DOI":"10.1016\/0378-5173(93)90317-9"},{"issue":"1","key":"2518_CR9","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1002\/app.10185","volume":"84","author":"A Rocha","year":"2002","unstructured":"Rocha A, Dantas T, Fonseca J, Pereira M (2002) Permeation of drugs in chitosan membranes. J Appl Polym Sci 84(1):44\u201349. https:\/\/doi.org\/10.1002\/app.10185","journal-title":"J Appl Polym Sci"},{"key":"2518_CR10","doi-asserted-by":"publisher","first-page":"4015","DOI":"10.2147\/IJN.S52605","volume":"8","author":"Y Wang","year":"2013","unstructured":"Wang Y, Zhao Q, Hu Y, Sun L, Bai L, Jiang T et al (2013) Ordered nanoporous silica as carriers for improved delivery of water insoluble drugs: a comparative study between three dimensional and two dimensional macroporous silica. Int J Nanomed 8:4015. https:\/\/doi.org\/10.2147\/IJN.S52605","journal-title":"Int J Nanomed"},{"issue":"2","key":"2518_CR11","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jconrel.2009.03.017","volume":"137","author":"M Kilpel\u00e4inen","year":"2009","unstructured":"Kilpel\u00e4inen M, Riikonen J, Vlasova M, Huotari A, Lehto V, Salonen J et al (2009) In vivo delivery of a peptide, ghrelin antagonist, with mesoporous silicon microparticles. J Control Release 137(2):166\u2013170. https:\/\/doi.org\/10.1016\/j.jconrel.2009.03.017","journal-title":"J Control Release"},{"issue":"8","key":"2518_CR12","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1002\/adfm.200601191","volume":"17","author":"II Slowing","year":"2007","unstructured":"Slowing II, Trewyn BG, Giri S, Lin VY (2007) Mesoporous silica nanoparticles for drug delivery and biosensing applications. Adv Funct Mater 17(8):1225\u20131236. https:\/\/doi.org\/10.1002\/adfm.200601191","journal-title":"Adv Funct Mater"},{"issue":"1","key":"2518_CR13","doi-asserted-by":"publisher","first-page":"99","DOI":"10.2217\/17435889.2.1.99","volume":"2","author":"S Giri","year":"2007","unstructured":"Giri S, Trewyn BG, Lin VS (2007) Mesoporous silica nanomaterial-based biotechnological and biomedical delivery systems. Nanomed J 2(1):99\u2013111. https:\/\/doi.org\/10.2217\/17435889.2.1.99","journal-title":"Nanomed J"},{"issue":"6","key":"2518_CR14","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1016\/j.biomaterials.2009.10.046","volume":"31","author":"Q He","year":"2010","unstructured":"He Q, Zhang J, Shi J, Zhu Z, Zhang L, Bu W et al (2010) The effect of PEGylation of mesoporous silica nanoparticles on nonspecific binding of serum proteins and cellular responses. Biomaterials 31(6):1085\u20131092. https:\/\/doi.org\/10.1016\/j.biomaterials.2009.10.046","journal-title":"Biomaterials"},{"issue":"11","key":"2518_CR15","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1016\/j.addr.2008.03.012","volume":"60","author":"II Slowing","year":"2008","unstructured":"Slowing II, Vivero-Escoto JL, Wu C-W, Lin VS-Y (2008) Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev 60(11):1278\u20131288. https:\/\/doi.org\/10.1016\/j.addr.2008.03.012","journal-title":"Adv Drug Deliv Rev"},{"key":"2518_CR16","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5168652","author":"Q Yi","year":"2019","unstructured":"Yi Q, Zou W-j (2019) The wound healing effect of doxycycline after corneal alkali burn in rats. J Ophthalmol. https:\/\/doi.org\/10.1155\/2019\/5168652","journal-title":"J Ophthalmol"},{"key":"2518_CR17","doi-asserted-by":"publisher","first-page":"109745","DOI":"10.1016\/j.msec.2019.109745","volume":"104","author":"S Cui","year":"2019","unstructured":"Cui S, Sun X, Li K, Gou D, Zhou Y, Hu J et al (2019) Polylactide nanofibers delivering doxycycline for chronic wound treatment. Mater Sci Eng C 104:109745. https:\/\/doi.org\/10.1016\/j.msec.2019.109745","journal-title":"Mater Sci Eng C"},{"key":"2518_CR18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.msec.2017.08.012","volume":"83","author":"R Ram\u00edrez-Agudelo","year":"2018","unstructured":"Ram\u00edrez-Agudelo R, Scheuermann K, Gala-Garc\u00eda A, Monteiro APF, Pinz\u00f3n-Garc\u00eda AD, Cort\u00e9s ME et al (2018) Hybrid nanofibers based on poly-caprolactone\/gelatin\/hydroxyapatite nanoparticles-loaded Doxycycline: Effective anti-tumoral and antibacterial activity. Mater Sci Eng C 83:25\u201334. https:\/\/doi.org\/10.1016\/j.msec.2017.08.012","journal-title":"Mater Sci Eng C"},{"issue":"5","key":"2518_CR19","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1080\/08941939.2021.1989728","volume":"35","author":"M Javdani","year":"2022","unstructured":"Javdani M, Barzegar A, Khosravian P, Hashemnia M (2022) Evaluation of inflammatory response due to use of controlled release drug delivery system of chitosan hydrogel loaded with buprenorphine and ketorolac in rat with experimental proximal tibial epiphysis defect. J Invest Surg 35(5):996\u20131011. https:\/\/doi.org\/10.1080\/08941939.2021.1989728","journal-title":"J Invest Surg"},{"issue":"2","key":"2518_CR20","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0376-4583(76)90024-8","volume":"4","author":"D Dollimore","year":"1976","unstructured":"Dollimore D, Spooner P, Turner A (1976) The BET method of analysis of gas adsorption data and its relevance to the calculation of surface areas. Surf Technol 4(2):121\u2013160. https:\/\/doi.org\/10.1016\/0376-4583(76)90024-8","journal-title":"Surf Technol"},{"issue":"6","key":"2518_CR21","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1573","volume":"11","author":"L Chen","year":"2019","unstructured":"Chen L, Zhou X, He C (2019) Mesoporous silica nanoparticles for tissue-engineering applications. Wiley Interdiscip Rev Nanomed Nanobiotechnol 11(6):e1573. https:\/\/doi.org\/10.1002\/wnan.1573","journal-title":"Wiley Interdiscip Rev Nanomed Nanobiotechnol"},{"issue":"12","key":"2518_CR22","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1002\/smll.200900005","volume":"5","author":"F Lu","year":"2009","unstructured":"Lu F, Wu SH, Hung Y, Mou CY (2009) Size effect on cell uptake in well-suspended, uniform mesoporous silica nanoparticles. Small 5(12):1408\u20131413. https:\/\/doi.org\/10.1002\/smll.200900005","journal-title":"Small"},{"key":"2518_CR23","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.ijbiomac.2018.11.045","volume":"124","author":"MA Khan","year":"2019","unstructured":"Khan MA, Mujahid M (2019) A review on recent advances in chitosan based composite for hemostatic dressings. Int J Biol Macromol 124:138\u2013147. https:\/\/doi.org\/10.1016\/j.ijbiomac.2018.11.045","journal-title":"Int J Biol Macromol"},{"key":"2518_CR24","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.tifs.2020.08.016","volume":"105","author":"K Mohan","year":"2020","unstructured":"Mohan K, Ganesan AR, Muralisankar T, Jayakumar R, Sathishkumar P, Uthayakumar V et al (2020) Recent insights into the extraction, characterization, and bioactivities of chitin and chitosan from insects. Trends Food Sci Technol 105:17\u201342. https:\/\/doi.org\/10.1016\/j.tifs.2020.08.016","journal-title":"Trends Food Sci Technol"},{"key":"2518_CR25","doi-asserted-by":"publisher","first-page":"650598","DOI":"10.3389\/fbioe.2021.650598","volume":"9","author":"P Feng","year":"2021","unstructured":"Feng P, Luo Y, Ke C, Qiu H, Wang W, Zhu Y et al (2021) Chitosan-based functional materials for skin wound repair: Mechanisms and applications. Front Bioeng Biotechnol 9:650598. https:\/\/doi.org\/10.3389\/fbioe.2021.650598","journal-title":"Front Bioeng Biotechnol"},{"key":"2518_CR26","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1016\/j.ijbiomac.2018.04.010","volume":"114","author":"MT Khorasani","year":"2018","unstructured":"Khorasani MT, Joorabloo A, Moghaddam A, Shamsi H, MansooriMoghadam Z (2018) Incorporation of ZnO nanoparticles into heparinised polyvinyl alcohol\/chitosan hydrogels for wound dressing application. Int J Biol Macromol 114:1203\u20131215. https:\/\/doi.org\/10.1016\/j.ijbiomac.2018.04.010","journal-title":"Int J Biol Macromol"},{"key":"2518_CR27","doi-asserted-by":"publisher","first-page":"125994","DOI":"10.1016\/j.cej.2020.125994","volume":"400","author":"B Zhang","year":"2020","unstructured":"Zhang B, He J, Shi M, Liang Y, Guo B (2020) Injectable self-healing supramolecular hydrogels with conductivity and photo-thermal antibacterial activity to enhance complete skin regeneration. Chem Eng J 400:125994. https:\/\/doi.org\/10.1016\/j.cej.2020.125994","journal-title":"Chem Eng J"},{"key":"2518_CR28","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.biomaterials.2018.08.044","volume":"183","author":"J Qu","year":"2018","unstructured":"Qu J, Zhao X, Liang Y, Zhang T, Ma PX, Guo B (2018) Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing. Biomaterials 183:185\u2013199. https:\/\/doi.org\/10.1016\/j.biomaterials.2018.08.044","journal-title":"Biomaterials"},{"issue":"1","key":"2518_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12951-020-00608-3","volume":"18","author":"C Mo","year":"2020","unstructured":"Mo C, Lu L, Liu D, Wei K (2020) Development of erianin-loaded dendritic mesoporous silica nanospheres with pro-apoptotic effects and enhanced topical delivery. J Nanobiotechnol 18(1):1\u201314. https:\/\/doi.org\/10.1186\/s12951-020-00608-3","journal-title":"J Nanobiotechnol"},{"issue":"3","key":"2518_CR30","doi-asserted-by":"publisher","first-page":"124","DOI":"10.4103\/2230-973X.160844","volume":"5","author":"C Bharti","year":"2015","unstructured":"Bharti C, Nagaich U, Pal AK, Gulati N (2015) Mesoporous silica nanoparticles in target drug delivery system: a review. Int J Pharm Investig 5(3):124. https:\/\/doi.org\/10.4103\/2230-973X.160844","journal-title":"Int J Pharm Investig"},{"issue":"10","key":"2518_CR31","doi-asserted-by":"publisher","first-page":"4940","DOI":"10.1039\/C7NR07898F","volume":"10","author":"R Gupta","year":"2018","unstructured":"Gupta R, Rai B (2018) In-silico design of nanoparticles for transdermal drug delivery application. Nanoscale 10(10):4940\u20134951. https:\/\/doi.org\/10.1039\/C7NR07898F","journal-title":"Nanoscale"},{"key":"2518_CR32","doi-asserted-by":"publisher","DOI":"10.1088\/1468-6996\/14\/4\/045005","author":"M Zhu","year":"2013","unstructured":"Zhu M, Zhu Y, Zhang L, Shi J (2013) Preparation of chitosan\/mesoporous silica nanoparticle composite hydrogels for sustained co-delivery of biomacromolecules and small chemical drugs. Sci Technol Adv Mater. https:\/\/doi.org\/10.1088\/1468-6996\/14\/4\/045005","journal-title":"Sci Technol Adv Mater"},{"issue":"7","key":"2518_CR33","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.3390\/pharmaceutics13071067","volume":"13","author":"E Rastegari","year":"2021","unstructured":"Rastegari E, Hsiao Y-J, Lai W-Y, Lai Y-H, Yang T-C, Chen S-J et al (2021) An update on mesoporous silica nanoparticle applications in nanomedicine. Pharmaceutics 13(7):1067. https:\/\/doi.org\/10.3390\/pharmaceutics13071067","journal-title":"Pharmaceutics"},{"issue":"3","key":"2518_CR34","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1038\/nri3623","volume":"14","author":"A Pellicoro","year":"2014","unstructured":"Pellicoro A, Ramachandran P, Iredale JP, Fallowfield JA (2014) Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat Rev Immunol 14(3):181\u2013194. https:\/\/doi.org\/10.1038\/nri3623","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"2518_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/ncomms4446","volume":"5","author":"CK Tsang","year":"2014","unstructured":"Tsang CK, Liu Y, Thomas J, Zhang Y, Zheng XS (2014) Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance. Nat Commun 5(1):1\u201311. https:\/\/doi.org\/10.1038\/ncomms4446","journal-title":"Nat Commun"},{"issue":"12","key":"2518_CR36","first-page":"339","volume":"24","author":"JR Wilcox","year":"2012","unstructured":"Wilcox JR, Covington DS, Paez N (2012) Doxycycline as a modulator of inflammation in chronic wounds. Wounds 24(12):339\u2013349","journal-title":"Wounds"},{"issue":"11","key":"2518_CR37","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1111\/j.1365-2362.2009.02199.x","volume":"39","author":"S Antoniou","year":"2009","unstructured":"Antoniou S, Antoniou G, Granderath F, Simopoulos C (2009) The role of matrix metalloproteinases in the pathogenesis of abdominal wall hernias. Eur J Clin Invest 39(11):953\u2013959. https:\/\/doi.org\/10.1111\/j.1365-2362.2009.02199.x","journal-title":"Eur J Clin Invest"},{"key":"2518_CR38","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-0185-9_14","author":"P Mignatti","year":"1988","unstructured":"Mignatti P, Rifkin DB, Welgus HG, Parks WC (1988) Proteinases and tissue remodeling. Mol Cell Biol. https:\/\/doi.org\/10.1007\/978-1-4899-0185-9_14","journal-title":"Mol Cell Biol"},{"key":"2518_CR39","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/329418","author":"R Di Caprio","year":"2015","unstructured":"Di Caprio R, Lembo S, Di Costanzo L, Balato A, Monfrecola G (2015) Anti-inflammatory properties of low and high doxycycline doses: an in vitro study. Mediators Inflamm. https:\/\/doi.org\/10.1155\/2015\/329418","journal-title":"Mediators Inflamm"},{"key":"2518_CR40","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.bbrep.2015.11.003","volume":"4","author":"J Sun","year":"2015","unstructured":"Sun J, Shigemi H, Tanaka Y, Yamauchi T, Ueda T, Iwasaki H (2015) Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-\u03baB signaling pathways. Biochem Biophys Rep 4:397\u2013404. https:\/\/doi.org\/10.1016\/j.bbrep.2015.11.003","journal-title":"Biochem Biophys Rep"},{"issue":"2","key":"2518_CR41","first-page":"49","volume":"31","author":"S Gabriele","year":"2018","unstructured":"Gabriele S, Buchanan B, Kundu A, Dwyer HC, Gabriele JP, Mayer P et al (2018) Stability, activity, and application of topical doxycycline formulations in a diabetic wound case study. Wounds 31(2):49\u201354","journal-title":"Wounds"},{"key":"2518_CR42","doi-asserted-by":"publisher","unstructured":"Hedayatyanfard K, Khoulenjani SB, Abdollahifar MA, Amani D, Habibi B, Zare F, et al (2020) Chitosan\/PVA\/Doxycycline film and nanofiber accelerate diabetic wound healing in a rat model. Iran J Pharm Sci 19(4):225. https:\/\/doi.org\/10.22037\/ijpr.2020.112620.13859","DOI":"10.22037\/ijpr.2020.112620.13859"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-022-02518-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00403-022-02518-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-022-02518-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T11:07:34Z","timestamp":1672225654000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00403-022-02518-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,28]]},"references-count":42,"alternative-id":["2518"],"URL":"https:\/\/doi.org\/10.1007\/s00403-022-02518-w","relation":{},"ISSN":["1432-069X"],"issn-type":[{"type":"electronic","value":"1432-069X"}],"subject":[],"published":{"date-parts":[[2022,12,28]]},"assertion":[{"value":"6 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 December 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All investigational procedures used in this study were reviewed and approved by the Council of Department of Veterinary Clinical Sciences of the Shahrekord University (13990925; P\/47\/170).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics, consent and permissions"}}]}}