{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T21:08:07Z","timestamp":1761253687066,"version":"3.37.3"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum D\u00fcsseldorf. Anstalt \u00f6ffentlichen Rechts"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Dermatol Res"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Information on the population-based incidence of psoriasis vulgaris was limited. This study was to provide a comprehensive understanding of the age-specific and sex-specific incidence of psoriasis vulgaris in Germany. The data were obtained in the context of a morbidity-based risk adjustment by statutory health insurance companies in Germany, comprising information regarding 65 million population. Psoriasis vulgaris diagnoses were made and coded according to the 10th edition of the International Statistical Classification of Diseases and Related Health Problems. Age-specific and sex-specific incidences were calculated using data from 2009 to 2011. There was a rise in the age- and sex-specific incidences of psoriasis vulgaris through midlife, reaching a peak at the age of 60 and subsequently declining for both genders. The peak incidence for men, at 130 cases per 100,000 person-years, slightly exceeded the peak incidence for women of 117 per 100,000 person-years. An increase in the overall incidence rate can also be observed over the course of the three-year period covered by the data. Considerable variations in the age- and sex-specific incidences of psoriasis vulgaris can be seen across the lifespan. Nevertheless, the overall age-standardized incidence for the German population was low compared to other European countries.<\/jats:p>","DOI":"10.1007\/s00403-023-02796-y","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T11:01:56Z","timestamp":1704366116000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Population-based incidence of psoriasis vulgaris in Germany: analysis of national statutory insurance data from 65 million population"],"prefix":"10.1007","volume":"316","author":[{"given":"Madeline","family":"Deike","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6284-9702","authenticated-orcid":false,"given":"Jiancong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0961-6592","authenticated-orcid":false,"given":"Ralph","family":"Brinks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Meller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart","family":"Ocker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0418-521X","authenticated-orcid":false,"given":"Falk G.","family":"Bechara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7408-9333","authenticated-orcid":false,"given":"J\u00f6rg H. W.","family":"Distler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9475-9362","authenticated-orcid":false,"given":"Xenofon","family":"Baraliakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1602-7649","authenticated-orcid":false,"given":"David","family":"Kiefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8465-6207","authenticated-orcid":false,"given":"Philipp","family":"Sewerin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,1,4]]},"reference":[{"key":"2796_CR1","doi-asserted-by":"publisher","first-page":"808","DOI":"10.2340\/00015555-2672","volume":"97","author":"A Egeberg","year":"2017","unstructured":"Egeberg A, Skov L, Gislason GH, Thyssen JP, Mallbris L (2017) Incidence and prevalence of psoriasis in Denmark. Acta Derm Venereol 97:808\u2013812. https:\/\/doi.org\/10.2340\/00015555-2672","journal-title":"Acta Derm Venereol"},{"key":"2796_CR2","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1111\/bjd.15021","volume":"176","author":"DA Springate","year":"2017","unstructured":"Springate DA, Parisi R, Kontopantelis E, Reeves D, Griffiths CE, Ashcroft DM (2017) Incidence, prevalence and mortality of patients with psoriasis: a U.K. population-based cohort study. Br J Dermatol 176:650\u2013658. https:\/\/doi.org\/10.1111\/bjd.15021","journal-title":"Br J Dermatol"},{"key":"2796_CR3","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1002\/acr.23743","volume":"71","author":"L Eder","year":"2019","unstructured":"Eder L, Widdifield J, Rosen CF, Cook R, Lee KA, Alhusayen R et al (2019) Trends in the prevalence and incidence of psoriasis and psoriatic arthritis in Ontario, Canada: a population-based study. Arthritis Care Res (Hoboken) 71:1084\u20131091. https:\/\/doi.org\/10.1002\/acr.23743","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"2796_CR4","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.jhealeco.2017.03.001","volume":"56","author":"S Bauhoff","year":"2017","unstructured":"Bauhoff S, Fischer L, G\u00f6pffarth D, Wuppermann AC (2017) Plan responses to diagnosis-based payment: evidence from Germany\u2019s morbidity-based risk adjustment. J Health Econ 56:397\u2013413. https:\/\/doi.org\/10.1016\/j.jhealeco.2017.03.001","journal-title":"J Health Econ"},{"key":"2796_CR5","doi-asserted-by":"publisher","unstructured":"Rommel A, Schmidt C (2018) Germany\u2019s data transparency regulations\u2014potential, developments and RKI federal health reporting activities. J Health Monit 3:11. https:\/\/doi.org\/10.17886\/rki-gbe-2018-056","DOI":"10.17886\/rki-gbe-2018-056"},{"key":"2796_CR6","unstructured":"Federal Office for Social Security (2023) Morbidity-Based Risk Structure Compensation (morbidit\u00e4tsorientierter Risikostrukturausgleich, Morbi-RSA). https:\/\/www.bundesamtsozialesicherung.de\/de\/themen\/risikostrukturausgleich\/rsa-einfach-erklaert\/ (In German). Accessed 9 Oct, 2023"},{"key":"2796_CR7","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s00403-012-1214-8","volume":"304","author":"A Nast","year":"2012","unstructured":"Nast A, Boehncke WH, Mrowietz U, Ockenfels HM, Philipp S, Reich K et al (2012) German S3-guidelines on the treatment of psoriasis vulgaris (short version). Arch Dermatol Res 304:87\u2013113. https:\/\/doi.org\/10.1007\/s00403-012-1214-8","journal-title":"Arch Dermatol Res"},{"key":"2796_CR8","unstructured":"German Institute for Medical Documentation and Information (DIMDI) (2023) Psoriasis vulgaris (Papulosquamous skin diseases [L40-L45]) diagnoses according to the 10th edition of the International Statistical Classification of Diseases and Related Health Problems (WHO Version 1.3). https:\/\/www.dimdi.de\/static\/de\/klassifikationen\/icd\/icd-10-who\/kode-suche\/htmlamtl\/index.htm?gm05.htm+ (In German). Accessed 8 Oct, 2023"},{"key":"2796_CR9","doi-asserted-by":"publisher","first-page":"400","DOI":"10.2340\/00015555-3130","volume":"99","author":"E Pezzolo","year":"2019","unstructured":"Pezzolo E, Cazzaniga S, Colombo P, Chatenoud L, Naldi L (2019) Psoriasis incidence and lifetime prevalence: suggestion for a higher mortality rate in older age-classes among psoriatic patients compared to the general population in Italy. Acta Derm Venereol 99:400\u2013403. https:\/\/doi.org\/10.2340\/00015555-3130","journal-title":"Acta Derm Venereol"},{"key":"2796_CR10","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2021-001975","author":"M Deike","year":"2021","unstructured":"Deike M, Brinks R, Meller S, Schneider M, Sewerin P (2021) Risk of psoriatic arthritis depending on age: analysis of data from 65 million people on statutory insurance in Germany. RMD Open. https:\/\/doi.org\/10.1136\/rmdopen-2021-001975","journal-title":"RMD Open"},{"key":"2796_CR11","doi-asserted-by":"publisher","first-page":"2070","DOI":"10.1002\/sim.5651","volume":"32","author":"R Brinks","year":"2013","unstructured":"Brinks R, Landwehr S, Icks A, Koch M, Giani G (2013) Deriving age-specific incidence from prevalence with an ordinary differential equation. Stat Med 32:2070\u20132078. https:\/\/doi.org\/10.1002\/sim.5651","journal-title":"Stat Med"},{"key":"2796_CR12","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1093\/imammb\/dqu024","volume":"32","author":"R Brinks","year":"2015","unstructured":"Brinks R, Landwehr S (2015) A new relation between prevalence and incidence of a chronic disease. Math Med Biol 32:425\u2013435. https:\/\/doi.org\/10.1093\/imammb\/dqu024","journal-title":"Math Med Biol"},{"key":"2796_CR13","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1111\/j.1365-2796.2010.02310.x","volume":"270","author":"O Ahlehoff","year":"2011","unstructured":"Ahlehoff O, Gislason GH, Charlot M, J\u00f8rgensen CH, Lindhardsen J, Olesen JB et al (2011) Psoriasis is associated with clinically significant cardiovascular risk: a Danish nationwide cohort study. J Intern Med 270:147\u2013157. https:\/\/doi.org\/10.1111\/j.1365-2796.2010.02310.x","journal-title":"J Intern Med"},{"key":"2796_CR14","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1111\/jdv.15762","volume":"33","author":"Y Schonmann","year":"2019","unstructured":"Schonmann Y, Ashcroft DM, Iskandar IYK, Parisi R, Sde-Or S, Comaneshter D et al (2019) Incidence and prevalence of psoriasis in Israel between 2011 and 2017. J Eur Acad Dermatol Venereol 33:2075\u20132081. https:\/\/doi.org\/10.1111\/jdv.15762","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2796_CR15","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1136\/annrheumdis-2018-214065","volume":"78","author":"P Sewerin","year":"2019","unstructured":"Sewerin P, Brinks R, Schneider M, Haase I, Vordenb\u00e4umen S (2019) Prevalence and incidence of psoriasis and psoriatic arthritis. Ann Rheum Dis 78:286\u2013287. https:\/\/doi.org\/10.1136\/annrheumdis-2018-214065","journal-title":"Ann Rheum Dis"},{"key":"2796_CR16","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.jaad.2008.10.062","volume":"60","author":"M Icen","year":"2009","unstructured":"Icen M, Crowson CS, McEvoy MT, Dann FJ, Gabriel SE, Maradit Kremers H (2009) Trends in incidence of adult-onset psoriasis over three decades: a population-based study. J Am Acad Dermatol 60:394\u2013401. https:\/\/doi.org\/10.1016\/j.jaad.2008.10.062","journal-title":"J Am Acad Dermatol"},{"key":"2796_CR17","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1093\/rheumatology\/keaa448","volume":"60","author":"L Pina Vegas","year":"2021","unstructured":"Pina Vegas L, Sbidian E, Penso L, Claudepierre P (2021) Epidemiologic study of patients with psoriatic arthritis in a real-world analysis: a cohort study of the French health insurance database. Rheumatology (Oxford) 60:1243\u20131251. https:\/\/doi.org\/10.1093\/rheumatology\/keaa448","journal-title":"Rheumatology (Oxford)"},{"key":"2796_CR18","doi-asserted-by":"publisher","unstructured":"Brinks R, T\u00f6nnies T, Hoyer A (2021) Impact of diagnostic accuracy on the estimation of excess mortality from incidence and prevalence: simulation study and application to diabetes in German men. F1000Res 10:49. https:\/\/doi.org\/10.12688\/f1000research.28023.1","DOI":"10.12688\/f1000research.28023.1"},{"key":"2796_CR19","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1590","volume":"369","author":"R Parisi","year":"2020","unstructured":"Parisi R, Iskandar IYK, Kontopantelis E, Augustin M, Griffiths CEM, Ashcroft DM (2020) National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study. BMJ 369:m1590. https:\/\/doi.org\/10.1136\/bmj.m1590","journal-title":"BMJ"},{"key":"2796_CR20","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/bjd.19169","volume":"184","author":"IYK Iskandar","year":"2021","unstructured":"Iskandar IYK, Parisi R, Griffiths CEM, Ashcroft DM (2021) Systematic review examining changes over time and variation in the incidence and prevalence of psoriasis by age and gender. Br J Dermatol 184:243\u2013258. https:\/\/doi.org\/10.1111\/bjd.19169","journal-title":"Br J Dermatol"},{"key":"2796_CR21","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1056\/NEJMra1505557","volume":"376","author":"CT Ritchlin","year":"2017","unstructured":"Ritchlin CT, Colbert RA, Gladman DD (2017) Psoriatic arthritis. N Engl J Med 376:957\u2013970. https:\/\/doi.org\/10.1056\/NEJMra1505557","journal-title":"N Engl J Med"},{"key":"2796_CR22","unstructured":"World Health Organization (2016) Global report on psoriasis. World Health Organization. https:\/\/apps.who.int\/iris\/handle\/10665\/204417. Accessed 8 Oct, 2023"},{"key":"2796_CR23","unstructured":"Federal Institute for Pharmaceuticals and Medical Products (2023) Health Research Data Center (Forschungsdatenzentrum Gesundheit). https:\/\/www.forschungsdatenzentrum-gesundheit.de\/faq\/faq-antrag-02\/ (In German). Accessed 8 Oct, 2023"}],"container-title":["Archives of Dermatological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-023-02796-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00403-023-02796-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00403-023-02796-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T16:03:16Z","timestamp":1707753796000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00403-023-02796-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,4]]},"references-count":23,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["2796"],"URL":"https:\/\/doi.org\/10.1007\/s00403-023-02796-y","relation":{},"ISSN":["1432-069X"],"issn-type":[{"type":"electronic","value":"1432-069X"}],"subject":[],"published":{"date-parts":[[2024,1,4]]},"assertion":[{"value":"12 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 December 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors declare that they have no conflict of interest relevant to this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All the datasets in the current study were in an aggregated data format; written informed consent and ethical approval were. Therefore, not required. All authors had full access to the study dataset and take responsibility for the integrity of the data and adherence to data protection protocols.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable\u2014our manuscript does not contain data from any individual person.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"65"}}