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One such group is people struggling with hypothyroidism. The market for preparations for hair growth and hair loss prevention includes betulin.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>This pilot study investigated its effect on hair loss in hypothyroid patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Study design<\/jats:title>\n                <jats:p>The study included a group of hypothyroid patients and a control group of people without hypothyroidism. Participants were randomly divided into a group taking placebo and betulin.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Results were investigated using photographic assessment of hair, trichoscopy and subjective evaluation of participants.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The study did not conclusively prove that betulin would contribute to the inhibition of hair loss or regrowth.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical Abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00403-024-02913-5","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T12:01:28Z","timestamp":1717243288000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of betulin oil on hair growth in hypothyroidism- a long-term blinded pilot study"],"prefix":"10.1007","volume":"316","author":[{"given":"Agata","family":"Serrafi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolina","family":"Gosty\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Kasprzak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Wasilewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Marczy\u0144ski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylwiusz","family":"Kontek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Lewandowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,1]]},"reference":[{"issue":"9","key":"2913_CR1","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1021\/np9800710","volume":"61","author":"Y Kashiwada","year":"2021","unstructured":"Kashiwada Y, Wang HK, Nagao T et al (2021) Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids. 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