{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:47:04Z","timestamp":1760906824195},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2004,3,13]],"date-time":"2004-03-13T00:00:00Z","timestamp":1079136000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1007\/s00404-003-0553-2","type":"journal-article","created":{"date-parts":[[2004,7,22]],"date-time":"2004-07-22T11:18:55Z","timestamp":1090495135000},"page":"244-251","source":"Crossref","is-referenced-by-count":15,"title":["An evaluation of maternal illnesses in the origin of neural-tube defects"],"prefix":"10.1007","volume":"270","author":[{"given":"Erika","family":"Medveczky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erzs\ufffdbet","family":"Puh\ufffd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew E.","family":"Czeizel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,3,13]]},"reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0140-6736(78)90881-4","volume":"1","author":"Chance","year":"1978","unstructured":"Chance PF, Smith DW (1978) Hyperthermia and meningomyelocele and anencephaly. Lancet 1:769?770","journal-title":"Lancet"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0022-3476(79)80092-X","volume":"95","author":"Clarren","year":"1979","unstructured":"Clarren SK, Smith DW, Harvey MAS et al (1979) Hyperthermia?a prospective evaluation of a possible teratogenic agent in man. J Pediatr 95:81?83","journal-title":"J Pediatr"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/(SICI)1096-9926(199705)55:5<299::AID-TERA1>3.0.CO;2-V","volume":"55","author":"Czeizel","year":"1997","unstructured":"Czeizel AE (1997) First 25\ufffdyears of the Hungarian Congenital Abnormality Registry. Teratology 55:299?305","journal-title":"Teratology"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1056\/NEJM199212243272602","volume":"327","author":"Czeizel","year":"1992","unstructured":"Czeizel AE, Dud\ufffds I (1992) Prevention of first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Eng J Med 327:1832?1835","journal-title":"N Eng J Med"},{"key":"CR5","first-page":"205","volume":"24","author":"Czeizel","year":"1970","unstructured":"Czeizel AE, R\ufffdv\ufffdsz C (1970) Major malformations of the central nervous system in Hungary. Br J Prev Soc Med 24:205?222","journal-title":"Br J Prev Soc Med"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF02390940","volume":"255","author":"Czeizel","year":"1994","unstructured":"Czeizel AE, Dud\ufffds I, M\ufffdtneki J (1994) Pregnancy outcomes in a randomised controlled trial of periconceptional multivitamin supplementation. Final report. Arch Gynecol Obstet 255:131?139","journal-title":"Arch Gynecol Obstet"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/tera.1032","volume":"63","author":"Czeizel","year":"2001","unstructured":"Czeizel AE, Rockenbauer M, Siffel CS, Varga E (2001) Description and mission evaluation of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980?1996. Teratology 63:176?185","journal-title":"Teratology"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/pds.766","volume":"12","author":"Czeizel","year":"2003","unstructured":"Czeizel AE, Petik D, Vargha P (2003) Validation studies of drug exposures in pregnant Women. Pharmacoepidemiol Drug Saf 12:409?416","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"CR9","unstructured":"Czeizel AE, Dob\ufffd M, Vargha P (2003) Hungarian two-cohort study of periconceptional multivitamin supplementation to prevent certain congenital abnormalities. J Am Med Ass (submitted)"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1542\/peds.68.4.480","volume":"68","author":"Fisher","year":"1981","unstructured":"Fisher NL, Smith DW (1981) Occipital encephalocele and early gestation hyperthermia. Pediatrics 68:480?483","journal-title":"Pediatrics"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/S0022-3476(81)80743-3","volume":"95","author":"Gomez","year":"1981","unstructured":"Gomez MR (1981) Possible teratogenicity of valproic acid. J Pediatr 95:508?509","journal-title":"J Pediatr"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0140-6736(78)91957-8","volume":"ii","author":"Halperin","year":"1978","unstructured":"Halperin LR, Wilroy RS Jr (1978) Maternal hyperthermia and neural tube defects. Lancet ii:212?213","journal-title":"Lancet"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/ajmg.1320190108","volume":"19","author":"Hunter","year":"1984","unstructured":"Hunter AGW (1984) Neural-tube defects in eastern Ontario and western Quebec: demography and family data. Am J Med Genet 19:45?63","journal-title":"Am J Med Genet"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/tera.1420140307","volume":"14","author":"Kilham","year":"1976","unstructured":"Kilham L, Ferm VH (1976) Exencephaly in fetal hamsters following exposure to hyperthermia. Teratology 14:23?326","journal-title":"Teratology"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0140-6736(79)92034-8","volume":"i","author":"Kleinbrecht","year":"1979","unstructured":"Kleinbrecht J, Michaelis H, Michaelis J, Koller S (1979) Fever in pregnancy and congenital anomalies. Lancet i:1403","journal-title":"Lancet"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/S0140-6736(89)92044-8","volume":"ii","author":"Koren","year":"1989","unstructured":"Koren G, Graham K, Sheav H, Einarson T (1989) Bias against the null hypothesis: the reproductive hazards of cocaine. Lancet ii:1440?1442","journal-title":"Lancet"},{"key":"CR17","first-page":"73","volume":"7","author":"Ku?era","year":"1971","unstructured":"Ku?era J (1971) Rate and type of congenital anomalies among offspring of diabetic women. J Reprod Med 7:73?82","journal-title":"J Reprod Med"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/tera.1420210114","volume":"21","author":"Layde","year":"1980","unstructured":"Layde PM, Edmonds LD, Erickson JD (1980) Maternal fever and neural tube defects. Teratology 21:105?108","journal-title":"Teratology"},{"key":"CR19","first-page":"70","volume":"17","author":"Leck","year":"1963","unstructured":"Leck I (1963) Incidence of malformations following influenza epidemics. Br J Prev Soc Med 17:70?80","journal-title":"Br J Prev Soc Med"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2307\/4594147","volume":"86","author":"Leck","year":"1971","unstructured":"Leck I (1971) Further tests of the hypothesis that influenza in pregnancy causes malformations. HSMHA Health Rep 86:265?269","journal-title":"HSMHA Health Rep"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S0140-6736(84)90557-9","volume":"ii","author":"Lindhout","year":"1984","unstructured":"Lindhout D, Meinardi H (1984) Spina bifida and in-utero exposure to valproate. Lancet ii:396","journal-title":"Lancet"},{"key":"CR22","doi-asserted-by":"crossref","unstructured":"Medveczky E, Puho E, Czeizel AE (2003) The use of drugs in mothers of offspring with neural-tube effects. Pharmacoepidemiol Drug Saf (in press)","DOI":"10.1002\/pds.900"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0140-6736(78)90549-4","volume":"1","author":"Miller","year":"1978","unstructured":"Miller P, Smith DW, Shepard TH (1978) Maternal hyperthermia as a possible cause of anencephaly. Lancet 1:519?521","journal-title":"Lancet"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/tera.1420250316","volume":"25","author":"Mills","year":"1982","unstructured":"Mills JL (1982) Malformations in infants of diabetic mothers. Teratology 25:385?394","journal-title":"Teratology"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1001\/jama.1992.03490070064043","volume":"268","author":"Milunsky","year":"1992","unstructured":"Milunsky A, Ulcickas M, Rothman KJ, Willett W, Jick SS, Jick H (1992) Maternal heat exposure and neural-tube defects. JAMA 268:882?885","journal-title":"JAMA"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(82)90908-4","volume":"ii","author":"Robert","year":"1982","unstructured":"Robert E, Guibaud P (1982) Maternal valproic acid and congenital neural tube defects. Lancet ii:937","journal-title":"Lancet"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1097\/00001648-200107000-00017","volume":"12","author":"Rockenbauer","year":"2001","unstructured":"Rockenbauer M, Olsen J, Czeizel AE, Pedersen L, S\ufffdrensen HT, EuroMap Group (2001) Recall bias in a case-control study on the use of medicine during pregnancy. Epidemiology 12:461?466","journal-title":"Epidemiology"},{"key":"CR28","unstructured":"Rosa F (1983) Pregnancy outcomes with maternal carbamazepine exposure. FDA ADR highlights no.11 FDA, Rockville, MD"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1056\/NEJM199103073241006","volume":"324","author":"Rosa","year":"1991","unstructured":"Rosa FW (1991) Spina bifida in infant of women treated with carbamazepine during pregnancy. N Engl J Med 324:674?677","journal-title":"N Engl J Med"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2105\/AJPH.80.4.473","volume":"80","author":"Sax\ufffdn","year":"1990","unstructured":"Sax\ufffdn L, Holmberg PC, Kurppa K et al (1990) Influenza epidemics and anencephaly. Am J Public Health 80:473?475","journal-title":"Am J Public Health"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1096-9926(199801)57:1<1::AID-TERA1>3.0.CO;2-6","volume":"57","author":"Shaw","year":"1998","unstructured":"Shaw GM, Todoroff K, Velie EM, Lammer EJ (1998) Maternal illness, including fever, and medication use as risk factors of neural-tube defects. Teratology 57:1?7","journal-title":"Teratology"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/ajmg.1320120306","volume":"12","author":"Shiota","year":"1982","unstructured":"Shiota K (1982) Neural-tube defects and maternal hyperthermia in early pregnancy. Epidemiology in a human embryo population. Am J Med Genet 12:281?288","journal-title":"Am J Med Genet"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-003-0553-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00404-003-0553-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-003-0553-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T02:10:56Z","timestamp":1682734256000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00404-003-0553-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,13]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["553"],"URL":"https:\/\/doi.org\/10.1007\/s00404-003-0553-2","relation":{},"ISSN":["0932-0067","1432-0711"],"issn-type":[{"value":"0932-0067","type":"print"},{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3,13]]}}}