{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:01:21Z","timestamp":1761919281868},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,1,6]],"date-time":"2010-01-06T00:00:00Z","timestamp":1262736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1007\/s00404-009-1340-5","type":"journal-article","created":{"date-parts":[[2010,1,5]],"date-time":"2010-01-05T04:45:48Z","timestamp":1262666748000},"page":"223-230","source":"Crossref","is-referenced-by-count":12,"title":["Inhibin\/activin-betaE subunit is expressed in normal and pathological human placental tissue including chorionic carcinoma cell lines"],"prefix":"10.1007","volume":"283","author":[{"given":"Andrea","family":"Gingelmaier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ansgar","family":"Br\u00fcning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Kimmich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Makovitzky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Bergauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Schiessl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Friese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Mylonas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,1,6]]},"reference":[{"key":"1340_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/JOE-08-0549","volume":"202","author":"Y Xia","year":"2009","unstructured":"Xia Y, Schneyer AL (2009) The biology of activin: recent advances in structure, regulation and function. J Endocrinol 202:1\u201312","journal-title":"J Endocrinol"},{"key":"1340_CR2","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1196\/annals.1315.023","volume":"1038","author":"W Vale","year":"2004","unstructured":"Vale W, Wiater E, Gray P, Harrison C, Bilezikjian L, Choe S (2004) Activins and inhibins and their signaling. Ann N Y Acad Sci 1038:142\u2013147","journal-title":"Ann N Y Acad Sci"},{"key":"1340_CR3","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s00418-004-0709-6","volume":"122","author":"I Mylonas","year":"2004","unstructured":"Mylonas I, Jeschke U, Wiest I, Hoeing A, Vogl J, Shabani N, Kuhn C, Schulze S, Kupka MS, Friese K (2004) Inhibin\/activin subunits alpha, beta-A and beta-B are differentially expressed in normal human endometrium throughout the menstrual cycle. Histochem Cell Biol 122:461\u2013471","journal-title":"Histochem Cell Biol"},{"key":"1340_CR4","first-page":"97","volume":"17","author":"S Worbs","year":"2007","unstructured":"Worbs S, Shabani N, Mayr D, Gingelmaier A, Makrigiannakis A, Kuhn C, Jeschke U, Kupka MS, Friese K, Mylonas I (2007) Expression of the inhibin\/activin subunits (-alpha, -betaA and -betaB) in normal and carcinogenic endometrial tissue: possible immunohistochemical differentiation markers. Oncol Rep 17:97\u2013104","journal-title":"Oncol Rep"},{"key":"1340_CR5","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/0002-9378(91)90323-J","volume":"165","author":"F Petraglia","year":"1991","unstructured":"Petraglia F, Garuti GC, Calza L, Roberts V, Giardino L, Genazzani AR, Vale W, Meunier H (1991) Inhibin subunits in human placenta: localization and messenger ribonucleic acid levels during pregnancy. Am J Obstet Gynecol 165:750\u2013758","journal-title":"Am J Obstet Gynecol"},{"key":"1340_CR6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10735-006-9029-6","volume":"37","author":"I Mylonas","year":"2006","unstructured":"Mylonas I, Schiessl B, Jeschke U, Vogl J, Makrigiannakis A, Kuhn C, Kunze S, Schulze S, Kainer F, Friese K (2006) Expression of inhibin\/activin subunits alpha (-alpha), betaA (-beta (A)) and betaB (-beta (B)) in placental tissue of normal and intrauterine growth restricted (IUGR) pregnancies. J Mol Histol 37:43\u201352","journal-title":"J Mol Histol"},{"key":"1340_CR7","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1385\/EP:17:1:19","volume":"17","author":"I Mylonas","year":"2006","unstructured":"Mylonas I, Schiessl B, Jeschke U, Vogl J, Makrigiannakis A, Kuhn C, Schulze S, Kainer F, Friese K (2006) Expression of inhibin\/activin subunits alpha (-alpha), betaA (-betaA), and betaB (-betaB) in placental tissue of normal, preeclamptic, and HELLP pregnancies. Endocr Pathol 17:19\u201333","journal-title":"Endocr Pathol"},{"key":"1340_CR8","first-page":"1995","volume":"27","author":"I Mylonas","year":"2007","unstructured":"Mylonas I, Shabani N, Vogl J, Makovitzky J, Kunze S, Kuhn C, Schulze S, Friese K, Jeschke U (2007) Inhibin\/activin subunits are immunohistochemically expressed in complete and partial hydatidiform moles. Anticancer Res 27:1995\u20132000","journal-title":"Anticancer Res"},{"key":"1340_CR9","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1177\/153537020222700905","volume":"227","author":"C Welt","year":"2002","unstructured":"Welt C, Sidis Y, Keutmann H, Schneyer A (2002) Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium. Exp Biol Med (Maywood) 227:724\u2013752","journal-title":"Exp Biol Med (Maywood)"},{"key":"1340_CR10","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/humupd\/8.6.529","volume":"8","author":"DM Kretser de","year":"2002","unstructured":"de Kretser DM, Hedger MP, Loveland KL, Phillips DJ (2002) Inhibins, activins and follistatin in reproduction. Hum Reprod Update 8:529\u2013541","journal-title":"Hum Reprod Update"},{"key":"1340_CR11","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/j.ejca.2009.01.008","volume":"45","author":"I Mylonas","year":"2009","unstructured":"Mylonas I, Worbs S, Shabani N, Kuhn C, Kunze S, Schulze S, Dian D, Gingelmaier A, Schindlbeck C, Bruning A, Sommer H, Jeschke U, Friese K (2009) Inhibin-alpha subunit is an independent prognostic parameter in human endometrial carcinomas: analysis of inhibin\/activin-alpha, -betaA and -betaB subunits in 302 cases. Eur J Cancer 45:1304\u20131314","journal-title":"Eur J Cancer"},{"key":"1340_CR12","first-page":"1","volume":"44","author":"W Vale","year":"1988","unstructured":"Vale W, Rivier C, Hsueh A, Campen C, Meunier H, Bicsak T, Vaughan J, Corrigan A, Bardin W, Sawchenko P et al (1988) Chemical and biological characterization of the inhibin family of protein hormones. Recent Prog Horm Res 44:1\u201334","journal-title":"Recent Prog Horm Res"},{"key":"1340_CR13","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1006\/bbrc.1995.1086","volume":"206","author":"G H\u00f6tten","year":"1995","unstructured":"H\u00f6tten G, Neidhardt H, Schneider C, Pohl J (1995) Cloning of a new member of the TGF-beta family: a putative new activin beta C chain. Biochem Biophys Res Commun 206:608\u2013613","journal-title":"Biochem Biophys Res Commun"},{"key":"1340_CR14","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1006\/bbrc.1995.1699","volume":"210","author":"S Oda","year":"1995","unstructured":"Oda S, Nishimatsu S, Murakami K, Ueno N (1995) Molecular cloning and functional analysis of a new activin beta subunit: a dorsal mesoderm-inducing activity in Xenopus. Biochem Biophys Res Commun 210:581\u2013588","journal-title":"Biochem Biophys Res Commun"},{"key":"1340_CR15","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1006\/bbrc.1996.1715","volume":"228","author":"J Fang","year":"1996","unstructured":"Fang J, Yin W, Smiley E, Wang SQ, Bonadio J (1996) Molecular cloning of the mouse activin betaE subunit gene. Biochem Biophys Res Commun 228:669\u2013674","journal-title":"Biochem Biophys Res Commun"},{"key":"1340_CR16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0303-7207(02)00157-0","volume":"194","author":"O Hashimoto","year":"2002","unstructured":"Hashimoto O, Tsuchida K, Ushiro Y, Hosoi Y, Hoshi N, Sugino H, Hasegawa Y (2002) cDNA cloning and expression of human activin betaE subunit. Mol Cell Endocrinol 194:117\u2013122","journal-title":"Mol Cell Endocrinol"},{"key":"1340_CR17","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1046\/j.1365-2559.1998.00385.x","volume":"32","author":"WG McCluggage","year":"1998","unstructured":"McCluggage WG, Ashe P, McBride H, Maxwell P, Sloan JM (1998) Localization of the cellular expression of inhibin in trophoblastic tissue. Histopathology 32:252\u2013256","journal-title":"Histopathology"},{"key":"1340_CR18","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/S0140-6736(96)09264-1","volume":"349","author":"S Muttukrishna","year":"1997","unstructured":"Muttukrishna S, Knight PG, Groome NP, Redman CW, Ledger WL (1997) Activin A and inhibin A as possible endocrine markers for pre-eclampsia. Lancet 349:1285\u20131288","journal-title":"Lancet"},{"key":"1340_CR19","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1056\/NEJM199605093341904","volume":"334","author":"DA Aitken","year":"1996","unstructured":"Aitken DA, Wallace EM, Crossley JA, Swanston IA, van Pareren Y, van Maarle M, Groome NP, Macri JN, Connor JM (1996) Dimeric inhibin A as a marker for Down\u2019s syndrome in early pregnancy. N Engl J Med 334:1231\u20131236","journal-title":"N Engl J Med"},{"key":"1340_CR20","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1369\/jhc.4A6480.2005","volume":"53","author":"B Schiessl","year":"2005","unstructured":"Schiessl B, Mylonas I, Hantschmann P, Kuhn C, Schulze S, Kunze S, Friese K, Jeschke U (2005) Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies. J Histochem Cytochem 53:1441\u20131449","journal-title":"J Histochem Cytochem"},{"key":"1340_CR21","first-page":"366","volume":"111","author":"I Mylonas","year":"2009","unstructured":"Mylonas I, Makovitzky J, Shabani N, Gingelmaier A, Dian D, Kuhn C, Schulze S, Kunze S, Jeschke U, Friese K (2009) Development and characterisation of an antibody for the immunohistochemical detection of inhibin\/activin betaE (betaE) in normal human ovarian and placental tissue. Acta Histochem 111:366\u2013371","journal-title":"Acta Histochem"},{"key":"1340_CR22","doi-asserted-by":"crossref","unstructured":"Kimmich T, Br\u00fcning A, K\u00e4ufl SD, Makovitzky J, Kuhn C, Jeschke U, Friese K, Mylonas I (2009) Inhibin\/activin-betaC and -betaE subunits in the Ishikawa human endometrial adenocarcinoma cell line. Arch Gynecol Obstet. doi: 10.1007\/s00404-009-1310-y","DOI":"10.1007\/s00404-009-1310-y"},{"key":"1340_CR23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00418-009-0595-z","volume":"132","author":"A Bruning","year":"2009","unstructured":"Bruning A, Makovitzky J, Gingelmaier A, Friese K, Mylonas I (2009) The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells. Histochem Cell Biol 132:33\u201338","journal-title":"Histochem Cell Biol"},{"key":"1340_CR24","doi-asserted-by":"crossref","unstructured":"Bergauer F, Br\u00fcning A, Shabani N, Blankenstein T, J\u00fcckstock J, Dian D, Mylonas I (2009) Inhibin\/activin-betaE subunit in normal and malignant human cervical tissue and cervical cancer cell lines. J Mol Histol. doi: 10.1007\/s10735-009-9246-x","DOI":"10.1007\/s10735-009-9246-x"},{"key":"1340_CR25","doi-asserted-by":"crossref","first-page":"6127","DOI":"10.1128\/MCB.20.16.6127-6137.2000","volume":"20","author":"AL Lau","year":"2000","unstructured":"Lau AL, Kumar TR, Nishimori K, Bonadio J, Matzuk MM (2000) Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol Cell Biol 20:6127\u20136137","journal-title":"Mol Cell Biol"},{"key":"1340_CR26","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0303-7207(01)00503-2","volume":"180","author":"P Florio","year":"2001","unstructured":"Florio P, Cobellis L, Luisi S, Ciarmela P, Severi FM, Bocchi C, Petraglia F (2001) Changes in inhibins and activin secretion in healthy and pathological pregnancies. Mol Cell Endocrinol 180:123\u2013130","journal-title":"Mol Cell Endocrinol"},{"key":"1340_CR27","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S1043-2760(01)00559-8","volume":"13","author":"RL Jones","year":"2002","unstructured":"Jones RL, Salamonsen LA, Findlay JK (2002) Potential roles for endometrial inhibins, activins and follistatin during human embryo implantation and early pregnancy. Trends Endocrinol Metab 13:144\u2013150","journal-title":"Trends Endocrinol Metab"},{"key":"1340_CR28","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1210\/en.138.9.3976","volume":"138","author":"I Caniggia","year":"1997","unstructured":"Caniggia I, Lye SJ, Cross JC (1997) Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology 138:3976\u20133986","journal-title":"Endocrinology"},{"key":"1340_CR29","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cytogfr.2009.02.007","volume":"20","author":"DJ Phillips","year":"2009","unstructured":"Phillips DJ, de Kretser DM, Hedger MP (2009) Activin and related proteins in inflammation: not just interested bystanders. Cytokine Growth Factor Rev 20:153\u2013164","journal-title":"Cytokine Growth Factor Rev"},{"key":"1340_CR30","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1053\/plac.1999.0451","volume":"21","author":"JA Keelan","year":"2000","unstructured":"Keelan JA, Zhou RL, Mitchell MD (2000) Activin A exerts both pro- and anti-inflammatory effects on human term gestational tissues. Placenta 21:38\u201343","journal-title":"Placenta"},{"key":"1340_CR31","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1093\/carcin\/bgg154","volume":"24","author":"S Vejda","year":"2003","unstructured":"Vejda S, Erlach N, Peter B, Drucker C, Rossmanith W, Pohl J, Schulte-Hermann R, Grusch M (2003) Expression of activins C and E induces apoptosis in human and rat hepatoma cells. Carcinogenesis 24:1801\u20131809","journal-title":"Carcinogenesis"},{"key":"1340_CR32","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1677\/jme.0.0280137","volume":"28","author":"S Vejda","year":"2002","unstructured":"Vejda S, Cranfield M, Peter B, Mellor SL, Groome N, Schulte-Hermann R, Rossmanith W (2002) Expression and dimerization of the rat activin subunits betaC and betaE: evidence for the ormation of novel activin dimers. J Mol Endocrinol 28:137\u2013148","journal-title":"J Mol Endocrinol"},{"key":"1340_CR33","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jss.2005.01.002","volume":"126","author":"K Takamura","year":"2005","unstructured":"Takamura K, Tsuchida K, Miyake H, Tashiro S, Sugino H (2005) Activin and activin receptor expression changes in liver regeneration in rat. J Surg Res 126:3\u201311","journal-title":"J Surg Res"},{"key":"1340_CR34","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1507\/endocrj.52.169","volume":"52","author":"W Wada","year":"2005","unstructured":"Wada W, Medina JJ, Kuwano H, Kojima I (2005) Comparison of the function of the beta(C) and beta(E) subunits of activin in AML12 hepatocytes. Endocr J 52:169\u2013175","journal-title":"Endocr J"},{"key":"1340_CR35","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.1210\/en.2003-0388","volume":"144","author":"M Chabicovsky","year":"2003","unstructured":"Chabicovsky M, Herkner K, Rossmanith W (2003) Overexpression of activin beta(C) or activin beta(E) in the mouse liver inhibits regenerative deoxyribonucleic acid synthesis of hepatic cells. Endocrinology 144:3497\u20133504","journal-title":"Endocrinology"},{"key":"1340_CR36","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.mrrev.2006.07.002","volume":"613","author":"C Rodgarkia-Dara","year":"2006","unstructured":"Rodgarkia-Dara C, Vejda S, Erlach N, Losert A, Bursch W, Berger W, Schulte-Hermann R, Grusch M (2006) The activin axis in liver biology and disease. Mutat Res 613:123\u2013137","journal-title":"Mutat Res"},{"key":"1340_CR37","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0303-7207(01)00516-0","volume":"180","author":"DJ Phillips","year":"2001","unstructured":"Phillips DJ, Jones KL, Scheerlinck JY, Hedger MP, de Kretser DM (2001) Evidence for activin A and follistatin involvement in the systemic inflammatory response. Mol Cell Endocrinol 180:155\u2013162","journal-title":"Mol Cell Endocrinol"},{"key":"1340_CR38","doi-asserted-by":"crossref","first-page":"23066","DOI":"10.1016\/S0021-9258(19)49426-X","volume":"268","author":"SA McCarthy","year":"1993","unstructured":"McCarthy SA, Bicknell R (1993) Inhibition of vascular endothelial cell growth by activin-A. J Biol Chem 268:23066\u201323071","journal-title":"J Biol Chem"},{"key":"1340_CR39","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1530\/eje.0.1470785","volume":"147","author":"NA Bersinger","year":"2002","unstructured":"Bersinger NA, Groome N, Muttukrishna S (2002) Pregnancy-associated and placental proteins in the placental tissue of normal pregnant women and patients with pre-eclampsia at term. Eur J Endocrinol 147:785\u2013793","journal-title":"Eur J Endocrinol"},{"key":"1340_CR40","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1093\/humrep\/15.7.1640","volume":"15","author":"S Muttukrishna","year":"2000","unstructured":"Muttukrishna S, North RA, Morris J, Schellenberg JC, Taylor RS, Asselin J, Ledger W, Groome N, Redman CW (2000) Serum inhibin A and activin A are elevated prior to the onset of pre-eclampsia. Hum Reprod 15:1640\u20131645","journal-title":"Hum Reprod"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-009-1340-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00404-009-1340-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-009-1340-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T19:24:19Z","timestamp":1634671459000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00404-009-1340-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,6]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["1340"],"URL":"https:\/\/doi.org\/10.1007\/s00404-009-1340-5","relation":{},"ISSN":["0932-0067","1432-0711"],"issn-type":[{"value":"0932-0067","type":"print"},{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,6]]}}}