{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T15:10:05Z","timestamp":1778253005263,"version":"3.51.4"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,9,8]],"date-time":"2013-09-08T00:00:00Z","timestamp":1378598400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1007\/s00404-013-2991-9","type":"journal-article","created":{"date-parts":[[2013,9,7]],"date-time":"2013-09-07T01:31:37Z","timestamp":1378517497000},"page":"581-593","source":"Crossref","is-referenced-by-count":25,"title":["eNOSI4 and EPHX1 polymorphisms affect maternal susceptibility to preeclampsia: analysis of five polymorphisms predisposing to cardiovascular disease in 279 Caucasian and 241 African women"],"prefix":"10.1007","volume":"289","author":[{"given":"T.","family":"Groten","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Schleussner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Lehmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Reister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Holzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. A.","family":"Danso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Zeillinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,9,8]]},"reference":[{"issue":"9741","key":"2991_CR1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","volume":"376","author":"EA Steegers","year":"2010","unstructured":"Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R (2010) Pre-eclampsia. Lancet 376(9741):631\u2013644. doi: 10.1016\/S0140-6736(10)60279-6","journal-title":"Lancet"},{"key":"2991_CR2","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2393-9-8","volume":"9","author":"K Haram","year":"2009","unstructured":"Haram K, Svendsen E, Abildgaard U (2009) The HELLP syndrome: clinical issues and management. A review. BMC Pregnancy Childbirth 9:8. doi: 10.1186\/1471-2393-9-8","journal-title":"BMC Pregnancy Childbirth"},{"issue":"3","key":"2991_CR3","doi-asserted-by":"crossref","first-page":"F614","DOI":"10.1152\/ajprenal.00470.2007","volume":"294","author":"MA Hladunewich","year":"2008","unstructured":"Hladunewich MA, Myers BD, Derby GC, Blouch KL, Druzin ML, Deen WM, Naimark DM, Lafayette RA (2008) Course of preeclamptic glomerular injury after delivery. Am J Physiol Ren Physiol 294(3):F614\u2013F620. doi: 10.1152\/ajprenal.00470.2007","journal-title":"Am J Physiol Ren Physiol"},{"issue":"7627","key":"2991_CR4","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1136\/bmj.39335.385301.BE","volume":"335","author":"L Bellamy","year":"2007","unstructured":"Bellamy L, Casas JP, Hingorani AD, Williams DJ (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 335(7627):974. doi: 10.1136\/bmj.39335.385301.BE","journal-title":"BMJ"},{"issue":"5","key":"2991_CR5","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ahj.2008.06.042","volume":"156","author":"SD McDonald","year":"2008","unstructured":"McDonald SD, Malinowski A, Zhou Q, Yusuf S, Devereaux PJ (2008) Cardiovascular sequelae of preeclampsia\/eclampsia: a systematic review and meta-analyses. Am Heart J 156(5):918\u2013930. doi: 10.1016\/j.ahj.2008.06.042","journal-title":"Am Heart J"},{"key":"2991_CR6","first-page":"858134","volume":"2011","author":"C Bushnell","year":"2011","unstructured":"Bushnell C, Chireau M (2011) Preeclampsia and stroke: risks during and after pregnancy. Stroke Res Treat 2011:858134. doi: 10.4061\/2011\/858134","journal-title":"Stroke Res Treat"},{"issue":"Suppl A","key":"2991_CR7","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1016\/j.placenta.2008.11.009","volume":"30","author":"JM Roberts","year":"2009","unstructured":"Roberts JM, Hubel CA (2009) The two stage model of preeclampsia: variations on the theme. Placenta 30(Suppl A):S32\u2013S37. doi: 10.1016\/j.placenta.2008.11.009","journal-title":"Placenta"},{"issue":"4","key":"2991_CR8","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1161\/HYPERTENSIONAHA.107.107607","volume":"51","author":"B Huppertz","year":"2008","unstructured":"Huppertz B (2008) Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 51(4):970\u2013975. doi: 10.1161\/HYPERTENSIONAHA.107.107607","journal-title":"Hypertension"},{"issue":"1","key":"2991_CR9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1515\/JPM.2008.004","volume":"36","author":"S Mutze","year":"2008","unstructured":"Mutze S, Rudnik-Schoneborn S, Zerres K, Rath W (2008) Genes and the preeclampsia syndrome. J Perinat Med 36(1):38\u201358. doi: 10.1515\/JPM.2008.004","journal-title":"J Perinat Med"},{"issue":"2","key":"2991_CR10","first-page":"330","volume":"66","author":"BM Schroeder","year":"2002","unstructured":"Schroeder BM (2002) ACOG practice bulletin on diagnosing and managing preeclampsia and eclampsia. American college of obstetricians and gynecologists. Am Fam Physician 66(2):330\u2013331","journal-title":"Am Fam Physician"},{"issue":"1","key":"2991_CR11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3109\/10641950109152647","volume":"20","author":"CB Tempfer","year":"2001","unstructured":"Tempfer CB, Dorman K, Deter RL, O\u2019Brien WE, Gregg AR (2001) An endothelial nitric oxide synthase gene polymorphism is associated with preeclampsia. Hypertens Pregnancy 20(1):107\u2013118. doi: 10.1081\/PRG-100104177","journal-title":"Hypertens Pregnancy"},{"issue":"4","key":"2991_CR12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jsgi.2003.12.002","volume":"11","author":"CB Tempfer","year":"2004","unstructured":"Tempfer CB, Jirecek S, Riener EK, Zeisler H, Denschlag D, Hefler L, Husslein PW (2004) Polymorphisms of thrombophilic and vasoactive genes and severe preeclampsia: a pilot study. J Soc Gynecol Investig 11(4):227\u2013231. doi: 10.1016\/j.jsgi.2003.12.002","journal-title":"J Soc Gynecol Investig"},{"issue":"2","key":"2991_CR13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ejogrb.2006.10.005","volume":"131","author":"I Medica","year":"2007","unstructured":"Medica I, Kastrin A, Peterlin B (2007) Genetic polymorphisms in vasoactive genes and preeclampsia: a meta-analysis. Eur J Obstet Gynecol Reprod Biol 131(2):115\u2013126. doi: 10.1016\/j.ejogrb.2006.10.005","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"1","key":"2991_CR14","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/ng0593-59","volume":"4","author":"K Ward","year":"1993","unstructured":"Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C, Farrington PF, Ogasawara M, Suzumori K, Tomoda S et al (1993) A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 4(1):59\u201361. doi: 10.1038\/ng0593-59","journal-title":"Nat Genet"},{"issue":"2","key":"2991_CR15","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1177\/0003319710373094","volume":"62","author":"T Motawi","year":"2011","unstructured":"Motawi T, Shaker O, Taha M, Sedrak H, Nabil M (2011) Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt. Angiology 62(2):191\u2013197. doi: 10.1177\/0003319710373094","journal-title":"Angiology"},{"issue":"1","key":"2991_CR16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0146-0005(99)80056-1","volume":"23","author":"T Morgan","year":"1999","unstructured":"Morgan T, Ward K (1999) New insights into the genetics of preeclampsia. Semin Perinatol 23(1):14\u201323","journal-title":"Semin Perinatol"},{"issue":"10","key":"2991_CR17","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1096\/fj.04-2558fje","volume":"19","author":"T Groten","year":"2005","unstructured":"Groten T, Pierce AA, Huen AC, Schnaper HW (2005) 17 beta-estradiol transiently disrupts adherens junctions in endothelial cells. FASEB J 19(10):1368\u20131370. doi: 10.1096\/fj.04-2558fje","journal-title":"FASEB J"},{"issue":"6","key":"2991_CR18","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1097\/00004872-200406000-00013","volume":"22","author":"JA Ellis","year":"2004","unstructured":"Ellis JA, Infantino T, Harrap SB (2004) Sex-dependent association of blood pressure with oestrogen receptor genes ERalpha and ERbeta. J Hypertens 22(6):1127\u20131131 (pii: 00004872-200406000-00013)","journal-title":"J Hypertens"},{"issue":"24","key":"2991_CR19","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1001\/jama.291.24.2969","volume":"291","author":"SC Schuit","year":"2004","unstructured":"Schuit SC, Oei HH, Witteman JC, Geurts van Kessel CH, van Meurs JB, Nijhuis RL, van Leeuwen JP, de Jong FH, Zillikens MC, Hofman A, Pols HA, Uitterlinden AG (2004) Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. JAMA 291(24):2969\u20132977. doi: 10.1001\/jama.291.24.2969","journal-title":"JAMA"},{"issue":"16","key":"2991_CR20","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1161\/01.CIR.0000016173.98826.88","volume":"105","author":"DM Herrington","year":"2002","unstructured":"Herrington DM, Howard TD, Brosnihan KB, McDonnell DP, Li X, Hawkins GA, Reboussin DM, Xu J, Zheng SL, Meyers DA, Bleecker ER (2002) Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. Circulation 105(16):1879\u20131882","journal-title":"Circulation"},{"issue":"3","key":"2991_CR21","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1291\/hypres.30.205","volume":"30","author":"A Molvarec","year":"2007","unstructured":"Molvarec A, Ver A, Fekete A, Rosta K, Derzbach L, Derzsy Z, Karadi I, Rigo J Jr (2007) Association between estrogen receptor alpha (ESR1) gene polymorphisms and severe preeclampsia. Hypertens Res 30(3):205\u2013211. doi: 10.1291\/hypres.30.205","journal-title":"Hypertens Res"},{"issue":"4","key":"2991_CR22","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1515\/CCLM.2009.096","volume":"47","author":"J Zhang","year":"2009","unstructured":"Zhang J, Bai H, Liu X, Fan P, Liu R, Huang Y, Wang X, He G, Liu Y, Liu B (2009) Genotype distribution of estrogen receptor alpha polymorphisms in pregnant women from healthy and preeclampsia populations and its relation to blood pressure levels. Clin Chem Lab Med 47(4):391\u2013397. doi: 10.1515\/CCLM.2009.096","journal-title":"Clin Chem Lab Med"},{"issue":"4","key":"2991_CR23","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1139\/h05-133","volume":"30","author":"JW Rush","year":"2005","unstructured":"Rush JW, Denniss SG, Graham DA (2005) Vascular nitric oxide and oxidative stress: determinants of endothelial adaptations to cardiovascular disease and to physical activity. Can J Appl Physiol 30(4):442\u2013474","journal-title":"Can J Appl Physiol"},{"issue":"3","key":"2991_CR24","doi-asserted-by":"crossref","first-page":"L529","DOI":"10.1152\/ajplung.2001.281.3.L529","volume":"281","author":"AB Fisher","year":"2001","unstructured":"Fisher AB, Chien S, Barakat AI, Nerem RM (2001) Endothelial cellular response to altered shear stress. Am J Physiol Lung Cell Mol Physiol 281(3):L529\u2013L533","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"37","key":"2991_CR25","doi-asserted-by":"crossref","first-page":"13683","DOI":"10.1073\/pnas.0402927101","volume":"101","author":"A Webb","year":"2004","unstructured":"Webb A, Bond R, McLean P, Uppal R, Benjamin N, Ahluwalia A (2004) Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. Proc Natl Acad Sci USA 101(37):13683\u201313688. doi: 10.1073\/pnas.0402927101","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"2991_CR26","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1471-0528.1996.tb09508.x","volume":"103","author":"NH Morris","year":"1996","unstructured":"Morris NH, Eaton BM, Dekker G (1996) Nitric oxide, the endothelium, pregnancy and pre-eclampsia. Br J Obstet Gynaecol 103(1):4\u201315","journal-title":"Br J Obstet Gynaecol"},{"issue":"5","key":"2991_CR27","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/01.fpc.0000199499.08725.d5","volume":"16","author":"M Nakayama","year":"2006","unstructured":"Nakayama M, Yoshimura M, Sakamoto T, Abe K, Yamamuro M, Shono M, Suzuki S, Nishijima T, Miyamoto Y, Saito Y, Nakao K, Yasue H, Ogawa H (2006) A -786T\u00a0>\u00a0C polymorphism in the endothelial nitric oxide synthase gene reduces serum nitrite\/nitrate levels from the heart due to an intracoronary injection of acetylcholine. Pharmacogenet Genomics 16(5):339\u2013345. doi: 10.1097\/01.fpc.0000199499.08725.d5","journal-title":"Pharmacogenet Genomics"},{"issue":"10","key":"2991_CR28","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1093\/aje\/kwj302","volume":"164","author":"JP Casas","year":"2006","unstructured":"Casas JP, Cavalleri GL, Bautista LE, Smeeth L, Humphries SE, Hingorani AD (2006) Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review. Am J Epidemiol 164(10):921\u2013935. doi: 10.1093\/aje\/kwj302","journal-title":"Am J Epidemiol"},{"issue":"10","key":"2991_CR29","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1097\/00004872-200210000-00022","volume":"20","author":"BA Veldman","year":"2002","unstructured":"Veldman BA, Spiering W, Doevendans PA, Vervoort G, Kroon AA, de Leeuw PW, Smits P (2002) The Glu298Asp polymorphism of the NOS 3 gene as a determinant of the baseline production of nitric oxide. J Hypertens 20(10):2023\u20132027","journal-title":"J Hypertens"},{"issue":"14","key":"2991_CR30","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1161\/01.CIR.100.14.1515","volume":"100","author":"AD Hingorani","year":"1999","unstructured":"Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, Haydock S, Hopper RV, Stephens NG, O\u2019Shaughnessy KM, Brown MJ (1999) A common variant of the endothelial nitric oxide synthase (Glu298\u2013\u00a0>\u00a0Asp) is a major risk factor for coronary artery disease in the UK. Circulation 100(14):1515\u20131520","journal-title":"Circulation"},{"issue":"5","key":"2991_CR31","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.thromres.2006.06.005","volume":"119","author":"IJ Kim","year":"2007","unstructured":"Kim IJ, Bae J, Lim SW, Cha DH, Cho HJ, Kim S, Yang DH, Hwang SG, Oh D, Kim NK (2007) Influence of endothelial nitric oxide synthase gene polymorphisms (-786T\u00a0>\u00a0C, 4a4b, 894G\u00a0>\u00a0T) in Korean patients with coronary artery disease. Thromb Res 119(5):579\u2013585. doi: 10.1016\/j.thromres.2006.06.005","journal-title":"Thromb Res"},{"issue":"2","key":"2991_CR32","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.arcmed.2007.08.002","volume":"39","author":"W Tang","year":"2008","unstructured":"Tang W, Yang Y, Wang B, Xiao C (2008) Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China. Arch Med Res 39(2):222\u2013225. doi: 10.1016\/j.arcmed.2007.08.002","journal-title":"Arch Med Res"},{"issue":"3","key":"2991_CR33","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S1071-5576(03)00003-0","volume":"10","author":"T Hakli","year":"2003","unstructured":"Hakli T, Romppanen EL, Hiltunen M, Helisalmi S, Punnonen K, Heinonen S (2003) Endothelial nitric oxide synthase polymorphism in preeclampsia. J Soc Gynecol Investig 10(3):154\u2013157 (pii:S1071557603000030)","journal-title":"J Soc Gynecol Investig"},{"issue":"5","key":"2991_CR34","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1161\/01.HYP.0000143483.66701.ec","volume":"44","author":"NC Serrano","year":"2004","unstructured":"Serrano NC, Casas JP, Diaz LA, Paez C, Mesa CM, Cifuentes R, Monterrosa A, Bautista A, Hawe E, Hingorani AD, Vallance P, Lopez-Jaramillo P (2004) Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study. Hypertension 44(5):702\u2013707. doi: 10.1161\/01.HYP.0000143483.66701.ec","journal-title":"Hypertension"},{"issue":"8","key":"2991_CR35","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/00008571-200111000-00011","volume":"11","author":"JE Tanus-Santos","year":"2001","unstructured":"Tanus-Santos JE, Desai M, Flockhart DA (2001) Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants. Pharmacogenetics 11(8):719\u2013725","journal-title":"Pharmacogenetics"},{"issue":"1","key":"2991_CR36","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1006\/bbrc.1998.8267","volume":"245","author":"T Tsukada","year":"1998","unstructured":"Tsukada T, Yokoyama K, Arai T, Takemoto F, Hara S, Yamada A, Kawaguchi Y, Hosoya T, Igari J (1998) Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans. Biochem Biophys Res Commun 245(1):190\u2013193. doi: 10.1006\/bbrc.1998.8267","journal-title":"Biochem Biophys Res Commun"},{"issue":"7","key":"2991_CR37","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1093\/molehr\/gaq030","volume":"16","author":"VC Sandrim","year":"2010","unstructured":"Sandrim VC, Palei AC, Sertorio JT, Cavalli RC, Duarte G, Tanus-Santos JE (2010) Effects of eNOS polymorphisms on nitric oxide formation in healthy pregnancy and in pre-eclampsia. Mol Hum Reprod 16(7):506\u2013510. doi: 10.1093\/molehr\/gaq030","journal-title":"Mol Hum Reprod"},{"issue":"4","key":"2991_CR38","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/mgme.2000.3033","volume":"70","author":"XL Wang","year":"2000","unstructured":"Wang XL, Wang J (2000) Endothelial nitric oxide synthase gene sequence variations and vascular disease. Mol Genet Metab 70(4):241\u2013251. doi: 10.1006\/mgme.2000.3033","journal-title":"Mol Genet Metab"},{"issue":"9","key":"2991_CR39","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1161\/01.STR.0000177978.97428.53","volume":"36","author":"TD Howard","year":"2005","unstructured":"Howard TD, Giles WH, Xu J, Wozniak MA, Malarcher AM, Lange LA, Macko RF, Basehore MJ, Meyers DA, Cole JW, Kittner SJ (2005) Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women. Stroke 36(9):1848\u20131851. doi: 10.1161\/01.STR.0000177978.97428.53","journal-title":"Stroke"},{"issue":"3","key":"2991_CR40","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1080\/003655100750044884","volume":"60","author":"HH Sigusch","year":"2000","unstructured":"Sigusch HH, Surber R, Lehmann MH, Surber S, Weber J, Henke A, Reinhardt D, Hoffmann A, Figulla HR (2000) Lack of association between 27-bp repeat polymorphism in intron 4 of the endothelial nitric oxide synthase gene and the risk of coronary artery disease. Scand J Clin Lab Invest 60(3):229\u2013235","journal-title":"Scand J Clin Lab Invest"},{"issue":"5","key":"2991_CR41","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/hr.2010.23","volume":"33","author":"PK Aggarwal","year":"2010","unstructured":"Aggarwal PK, Jain V, Jha V (2010) Endothelial nitric oxide synthase, angiotensin-converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy. Hypertens Res 33(5):473\u2013477. doi: 10.1038\/hr.2010.23","journal-title":"Hypertens Res"},{"issue":"4","key":"2991_CR42","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00204-009-0416-0","volume":"83","author":"M Decker","year":"2009","unstructured":"Decker M, Arand M, Cronin A (2009) Mammalian epoxide hydrolases in xenobiotic metabolism and signalling. Arch Toxicol 83(4):297\u2013318. doi: 10.1007\/s00204-009-0416-0","journal-title":"Arch Toxicol"},{"issue":"5","key":"2991_CR43","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/ng.129","volume":"40","author":"J Monti","year":"2008","unstructured":"Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gosele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Lindpaintner K, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck WH, Luft FC, Hubner N (2008) Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. Nat Genet 40(5):529\u2013537. doi: 10.1038\/ng.129","journal-title":"Nat Genet"},{"issue":"3","key":"2991_CR44","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3109\/00498259509061848","volume":"25","author":"F Fandrich","year":"1995","unstructured":"Fandrich F, Degiuli B, Vogel-Bindel U, Arand M, Oesch F (1995) Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16 alpha, 17 alpha-epoxyestra-1,3,5-trien-3-ol. Xenobiotica 25(3):239\u2013244. doi: 10.3109\/00498259509061848","journal-title":"Xenobiotica"},{"issue":"8","key":"2991_CR45","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1111\/j.1460-9568.2006.04724.x","volume":"23","author":"M Liu","year":"2006","unstructured":"Liu M, Sun A, Shin EJ, Liu X, Kim SG, Runyons CR, Markesbery W, Kim HC, Bing G (2006) Expression of microsomal epoxide hydrolase is elevated in Alzheimer\u2019s hippocampus and induced by exogenous beta-amyloid and trimethyl-tin. Eur J Neurosci 23(8):2027\u20132034. doi: 10.1111\/j.1460-9568.2006.04724.x","journal-title":"Eur J Neurosci"},{"issue":"8","key":"2991_CR46","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/00008571-200111000-00009","volume":"11","author":"FM Farin","year":"2001","unstructured":"Farin FM, Janssen P, Quigley S, Abbott D, Hassett C, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Omiecinski CJ, Checkoway H (2001) Genetic polymorphisms of microsomal and soluble epoxide hydrolase and the risk of Parkinson\u2019s disease. Pharmacogenetics 11(8):703\u2013708","journal-title":"Pharmacogenetics"},{"issue":"4","key":"2991_CR47","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/0006-2952(92)90243-C","volume":"43","author":"DK Robbins","year":"1992","unstructured":"Robbins DK, Wedlund PJ, Elsberg S, Oesch F, Thomas H (1992) Interaction of valproic acid and some analogues with microsomal epoxide hydrolase. Biochem Pharmacol 43(4):775\u2013783","journal-title":"Biochem Pharmacol"},{"key":"2991_CR48","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0378-4274(99)00235-0","volume":"112\u2013113","author":"CJ Omiecinski","year":"2000","unstructured":"Omiecinski CJ, Hassett C, Hosagrahara V (2000) Epoxide hydrolase-polymorphism and role in toxicology. Toxicol Lett 112\u2013113:365\u2013370 (pii: S0378427499002350)","journal-title":"Toxicol Lett"},{"issue":"2","key":"2991_CR49","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/abbi.1996.9794","volume":"337","author":"C Hassett","year":"1997","unstructured":"Hassett C, Lin J, Carty CL, Laurenzana EM, Omiecinski CJ (1997) Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression. Arch Biochem Biophys 337(2):275\u2013283. doi: 10.1006\/abbi.1996.9794","journal-title":"Arch Biochem Biophys"},{"key":"2991_CR50","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1471-2407-8-60","volume":"8","author":"A Rosenberger","year":"2008","unstructured":"Rosenberger A, Illig T, Korb K, Klopp N, Zietemann V, Wolke G, Meese E, Sybrecht G, Kronenberg F, Cebulla M, Degen M, Drings P, Groschel A, Konietzko N, Kreymborg KG, Haussinger K, Hoffken G, Jilge B, Ko YD, Morr H, Schmidt C, Schmidt EW, Tauscher D, Bickeboller H, Wichmann HE (2008) Do genetic factors protect for early onset lung cancer? A case control study before the age of 50\u00a0years. BMC Cancer 8:60. doi: 10.1186\/1471-2407-8-60","journal-title":"BMC Cancer"},{"issue":"4","key":"2991_CR51","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1136\/jmg.38.4.234","volume":"38","author":"PL Zusterzeel","year":"2001","unstructured":"Zusterzeel PL, Peters WH, Visser W, Hermsen KJ, Roelofs HM, Steegers EA (2001) A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia. J Med Genet 38(4):234\u2013237","journal-title":"J Med Genet"},{"issue":"1","key":"2991_CR52","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1447-0756.2007.00473.x","volume":"33","author":"E Pinarbasi","year":"2007","unstructured":"Pinarbasi E, Percin FE, Yilmaz M, Akgun E, Cetin M, Cetin A (2007) Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women. J Obstet Gynaecol Res 33(1):32\u201337. doi: 10.1111\/j.1447-0756.2007.00473.x","journal-title":"J Obstet Gynaecol Res"},{"issue":"9","key":"2991_CR53","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/sj.ejhg.5200849","volume":"10","author":"J Laasanen","year":"2002","unstructured":"Laasanen J, Romppanen EL, Hiltunen M, Helisalmi S, Mannermaa A, Punnonen K, Heinonen S (2002) Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia. Eur J Hum Genet 10(9):569\u2013573. doi: 10.1038\/sj.ejhg.5200849","journal-title":"Eur J Hum Genet"},{"issue":"8","key":"2991_CR54","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1080\/01443610400018841","volume":"24","author":"GS Gebhardt","year":"2004","unstructured":"Gebhardt GS, Peters WH, Hillermann R, Odendaal HJ, Carelse-Tofa K, Raijmakers MT, Steegers EA (2004) Maternal and fetal single nucleotide polymorphisms in the epoxide hydrolase and gluthatione S-transferase P1 genes are not associated with pre-eclampsia in the Coloured population of the Western Cape. South Africa. J Obstet Gynaecol 24(8):866\u2013872. doi: 10.1080\/01443610400018841","journal-title":"South Africa. J Obstet Gynaecol"},{"issue":"3","key":"2991_CR55","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1159\/000317521","volume":"86","author":"MH Yousif","year":"2010","unstructured":"Yousif MH, Benter IF (2010) Role of 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of vascular function in a model of hypertension and endothelial dysfunction. Pharmacology 86(3):149\u2013156. doi: 10.1159\/000317521","journal-title":"Pharmacology"},{"issue":"1","key":"2991_CR56","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ejphar.2010.12.016","volume":"654","author":"LN Zhang","year":"2011","unstructured":"Zhang LN, Vincelette J, Chen D, Gless RD, Anandan SK, Rubanyi GM, Webb HK, MacIntyre DE, Wang YX (2011) Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension. Eur J Pharmacol 654(1):68\u201374. doi: 10.1016\/j.ejphar.2010.12.016","journal-title":"Eur J Pharmacol"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-013-2991-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00404-013-2991-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-013-2991-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,23]],"date-time":"2019-07-23T11:25:43Z","timestamp":1563881143000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00404-013-2991-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,8]]},"references-count":56,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["2991"],"URL":"https:\/\/doi.org\/10.1007\/s00404-013-2991-9","relation":{},"ISSN":["0932-0067","1432-0711"],"issn-type":[{"value":"0932-0067","type":"print"},{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,8]]}}}