{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T12:09:13Z","timestamp":1785499753143,"version":"3.56.0"},"update-to":[{"DOI":"10.1007\/s00404-015-3767-1","type":"expression_of_concern","label":"Expression of concern","source":"retraction-watch","updated":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T00:00:00Z","timestamp":1590537600000},"record-id":"31203"}],"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T00:00:00Z","timestamp":1433462400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T00:00:00Z","timestamp":1433462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1007\/s00404-015-3767-1","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T16:15:07Z","timestamp":1433434507000},"page":"61-67","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["RETRACTED ARTICLE: Vaginal progesterone for prevention of\n              preterm labor in asymptomatic twin pregnancies with sonographic short cervix: a\n              randomized clinical trial of efficacy and safety"],"prefix":"10.1007","volume":"293","author":[{"given":"Waleed","family":"El-refaie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"Abdelhafez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Badawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,6,5]]},"reference":[{"key":"3767_CR1","first-page":"13","volume":"35","author":"K Moser","year":"2007","unstructured":"Moser K, Macfarlane A, Chow YH, Hilder L, Dattani N (2007)\n                  Introducing new data on gestation-specific infant mortality among babies born in\n                  2005 in England and Wales. Health Stat Q 35:13\u201327","journal-title":"Health Stat Q"},{"issue":"7217","key":"3767_CR2","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1136\/bmj.319.7217.1093","volume":"319","author":"ES Draper","year":"1999","unstructured":"Draper ES, Manktelow B, Field DJ, James D (1999) Prediction of\n                  survival for preterm births by weight and gestational age: retrospective\n                  population based study. BMJ 319(7217):1093\u20131097","journal-title":"BMJ"},{"issue":"1 Pt 1","key":"3767_CR3","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/S0002-9378(96)70375-7","volume":"174","author":"SJ Kilpatrick","year":"1996","unstructured":"Kilpatrick SJ, Jackson R, Croughan-Minihane MS (1996) Perinatal\n                  mortality in twins and singletons matched for gestational age at delivery at \u226530\n                  weeks. Am J Obstet Gynecol 174(1 Pt 1):66\u201371","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"3767_CR4","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/0029-7844(94)00455-M","volume":"85","author":"MO Gardner","year":"1995","unstructured":"Gardner MO, Goldenberg RL, Cliver SP, Tucker JM, Nelson KG, Copper\n                  RL (1995) The origin and outcome of preterm twin pregnancies. Obstet Gynecol\n                  85(4):553\u2013557","journal-title":"Obstet Gynecol"},{"issue":"6","key":"3767_CR5","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1067\/mob.2000.106851","volume":"182","author":"SS Hassan","year":"2000","unstructured":"Hassan SS, Romero R, Berry SM, Dang K, Blackwell SC, Treadwell MC\n                  et al (2000) Patients with an ultrasonographic cervical length \u226415\u00a0mm have nearly\n                  a 50\u00a0% risk of early spontaneous preterm delivery. Am J Obstet Gynecol\n                  182(6):1458\u20131467","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"3767_CR6","first-page":"450","volume":"94","author":"AP Souka","year":"1999","unstructured":"Souka AP, Heath V, Flint S, Sevastopoulou I, Nicolaides KH (1999)\n                  Cervical length at 23\u00a0weeks in twins in predicting spontaneous preterm delivery.\n                  Obstet Gynecol 94(3):450\u2013454","journal-title":"Obstet Gynecol"},{"issue":"4","key":"3767_CR7","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1007\/s00404-013-2740-0","volume":"287","author":"HA Guimar\u00e3es Filho","year":"2013","unstructured":"Guimar\u00e3es Filho HA, Araujo J\u00fanior E, Pires CR, Nardozza LM, Moron\n                  AF (2013) Short cervix syndrome: current knowledge from etiology to the control.\n                  Arch Gynecol Obstet 287(4):621\u2013628","journal-title":"Arch Gynecol Obstet"},{"issue":"5","key":"3767_CR8","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1002\/uog.5158","volume":"30","author":"JM O\u2019Brien","year":"2007","unstructured":"O\u2019Brien JM, Adair CD, Lewis DF, Hall DR, Defranco EA, Fusey S et al\n                  (2007) Progesterone vaginal gel for the reduction of recurrent preterm birth:\n                  primary results from a randomized, double-blind, placebo-controlled trial.\n                  Ultrasound Obstet Gynecol 30(5):687\u2013696","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"6","key":"3767_CR9","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1002\/uog.7338","volume":"34","author":"JM O\u2019Brien","year":"2009","unstructured":"O\u2019Brien JM, Defranco EA, Adair CD, Lewis DF, Hall DR, How H et al\n                  (2009) Effect of progesterone on cervical shortening in women at risk for preterm\n                  birth: secondary analysis from a multinational, randomized, double-blind,\n                  placebo-controlled trial. Ultrasound Obstet Gynecol\n                  34(6):653\u2013659","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"5","key":"3767_CR10","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1002\/uog.5159","volume":"30","author":"EA DeFranco","year":"2007","unstructured":"DeFranco EA, O\u2019Brien JM, Adair CD, Lewis DF, Hall DR, Fusey S et al\n                  (2007) Vaginal progesterone is associated with a decrease in risk for early\n                  preterm birth and improved neonatal outcome in women with a short cervix: a\n                  secondary analysis from a randomized, double-blind, placebo-controlled trial.\n                  Ultrasound Obstet Gynecol 30(5):697\u2013705","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"5","key":"3767_CR11","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1056\/NEJMoa067815","volume":"357","author":"Eduardo B. Fonseca","year":"2007","unstructured":"Fonseca EB, Celik E, Parra M, Singh M, Nicolaides KH, Fetal\n                  Medicine Foundation Second Trimester Screening Group (2007) Progesterone and the\n                  risk of preterm birth among women with a short cervix. N Engl J Med\n                  357(5):462\u2013469","journal-title":"New England Journal of Medicine"},{"issue":"1","key":"3767_CR12","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1002\/uog.9017","volume":"38","author":"SS Hassan","year":"2011","unstructured":"Hassan SS, Romero R, Vidyadhari D, Fusey S, Baxter JK, Khandelwal M\n                  et al (2011) Vaginal progesterone reduces the rate of preterm birth in women with\n                  a sonographic short cervix: a multicenter, randomized, double-blind,\n                  placebo-controlled trial. Ultrasound Obstet Gynecol 38(1):18\u201331","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"2","key":"3767_CR13","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00404-011-1973-z","volume":"285","author":"A Gezer","year":"2012","unstructured":"Gezer A, Rashidova M, G\u00fcralp O, O\u00e7er F (2012) Perinatal mortality\n                  and morbidity in twin pregnancies: the relation between chorionicity and\n                  gestational age at birth. Arch Gynecol Obstet 285(2):353\u2013360","journal-title":"Arch Gynecol Obstet"},{"issue":"5","key":"3767_CR14","first-page":"514","volume":"21","author":"JRG Challis","year":"2000","unstructured":"Challis JRG, Matthews SG, Gibb W, Lye SJ (2000) Endocrine and\n                  paracrine regulation of birth at term and preterm. Endocr Rev\n                  21(5):514\u2013550","journal-title":"Endocr Rev"},{"issue":"9","key":"3767_CR15","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1056\/NEJM199908263410906","volume":"341","author":"ER Norwitz","year":"1999","unstructured":"Norwitz ER, Robinson JN, Challis JR (1999) The control of labor. N\n                  Engl J Med 341(9):660\u2013666","journal-title":"N Engl J Med"},{"key":"3767_CR16","unstructured":"FDA statement on Makena [news release]. US Department of Health and\n                  Human Services, US Food and Drug Administration, Silver Spring, Maryland. http:\/\/www.fda.gov\/NewsEvents\/Newsroom\/PressAnnouncements\/ucm249025.htm. 30 March 2011"},{"issue":"6","key":"3767_CR17","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1007\/s00404-013-2789-9","volume":"287","author":"DR Velez Edwards","year":"2013","unstructured":"Velez Edwards DR, Likis FE, Andrews JC, Woodworth AL, Jerome RN,\n                  Fonnesbeck CJ et al (2013) Progestogens for preterm birth prevention: a systematic\n                  review and meta-analysis by drug route. Arch Gynecol Obstet\n                  287(6):1059\u20131066","journal-title":"Arch Gynecol Obstet"},{"issue":"5","key":"3767_CR18","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1067\/mob.2001.118655","volume":"185","author":"SM Althuisius","year":"2001","unstructured":"Althuisius SM, Dekker GA, Hummel P, Bekedam DJ, van Geijn HP (2001)\n                  Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial\n                  (CIPRACT): therapeutic cerclage with bed rest versus bed rest alone. Am J Obstet\n                  Gynecol 185(5):1106\u20131112","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"3767_CR19","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1067\/mob.2003.41","volume":"188","author":"EB da Fonseca","year":"2003","unstructured":"da Fonseca EB, Bittar RE, Carvalho MH, Zugaib M (2003) Prophylactic\n                  administration of progesterone by vaginal suppository to reduce the incidence of\n                  spontaneous preterm birth in women at increased risk: a randomized\n                  placebo-controlled double-blind study. Am J Obstet Gynecol\n                  188(2):419\u2013424","journal-title":"Am J Obstet Gynecol"},{"issue":"24","key":"3767_CR20","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1056\/NEJMoa035140","volume":"348","author":"PJ Meis","year":"2003","unstructured":"Meis PJ, Klebanoff M, Thom E, Dombrowski MP, Sibai B, Moawad AH et\n                  al (2003) Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone\n                  caproate. N Engl J Med 348(24):2379\u20132385","journal-title":"N Engl J Med"},{"issue":"5","key":"3767_CR21","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1056\/NEJMoa070641","volume":"357","author":"DJ Rouse","year":"2007","unstructured":"Rouse DJ, Caritis SN, Peaceman AM, Sciscione A, Thom EA, Spong CY\n                  et al (2007) A trial of 17 alpha-hydroxyprogesterone caproate to prevent\n                  prematurity in twins. N Engl J Med 357(5):454\u2013461","journal-title":"N Engl J Med"},{"issue":"9680","key":"3767_CR22","doi-asserted-by":"publisher","first-page":"2034","DOI":"10.1016\/S0140-6736(09)60947-8","volume":"373","author":"JE Norman","year":"2009","unstructured":"Norman JE, Mackenzie F, Owen P, Mactier H, Hanretty K, Cooper S et\n                  al (2009) Progesterone for the prevention of preterm birth in twin pregnancy\n                  (STOPPIT): a randomised, double-blind, placebo-controlled study and meta-analysis.\n                  Lancet 373(9680):2034\u20132040","journal-title":"Lancet"},{"issue":"2","key":"3767_CR23","doi-asserted-by":"publisher","first-page":"124.e1-124.e19","DOI":"10.1016\/j.ajog.2011.12.003","volume":"206","author":"Roberto Romero","year":"2012","unstructured":"Romero R, Nicolaides K, Conde-Agudelo A, Tabor A, O\u2019Brien JM,\n                  Cetingoz E et al (2012) Vaginal progesterone in women with an asymptomatic\n                  sonographic short cervix in the midtrimester decreases preterm delivery and\n                  neonatal morbidity: a systematic review and metaanalysis of individual patient\n                  data. Am J Obstet Gynecol 206(2):124.e1\u201319","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"1","key":"3767_CR24","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/1471-0528.13032","volume":"122","author":"E Schuit","year":"2015","unstructured":"Schuit E, Stock S, Rode L, Rouse DJ, Lim AC, Norman JE et al (2015)\n                  Effectiveness of progestogens to improve perinatal outcome in twin pregnancies: an\n                  individual participant data meta-analysis. BJOG 122(1):27\u201337","journal-title":"BJOG"},{"issue":"2","key":"3767_CR25","doi-asserted-by":"publisher","first-page":"128.e1-128.e12","DOI":"10.1016\/j.ajog.2010.02.064","volume":"203","author":"Agust\u00edn Conde-Agudelo","year":"2010","unstructured":"Conde-Agudelo A, Romero R, Hassan SS, Yeo L (2010) Transvaginal\n                  sonographic cervical length for the prediction of spontaneous preterm birth in\n                  twin pregnancies: a systematic review and metaanalysis. Am J Obstet Gynecol\n                  203(2):128.e1\u201312","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"2","key":"3767_CR26","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s00404-013-2758-3","volume":"288","author":"C Zanardini","year":"2013","unstructured":"Zanardini C, Pagani G, Fichera A, Prefumo F, Frusca T (2013)\n                  Cervical cerclage in twin pregnancies. Arch Gynecol Obstet\n                  288(2):267\u2013271","journal-title":"Arch Gynecol Obstet"}],"updated-by":[{"DOI":"10.1007\/s00404-015-3767-1","type":"expression_of_concern","label":"Expression of concern","source":"retraction-watch","updated":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T00:00:00Z","timestamp":1590537600000},"record-id":"31203"},{"DOI":"10.1007\/s00404-021-06152-1","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T00:00:00Z","timestamp":1627344000000},"record-id":"31202"},{"DOI":"10.1007\/s00404-021-06152-1","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T00:00:00Z","timestamp":1627344000000}}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-015-3767-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-015-3767-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-015-3767-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-015-3767-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T09:07:03Z","timestamp":1627463223000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-015-3767-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,5]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["3767"],"URL":"https:\/\/doi.org\/10.1007\/s00404-015-3767-1","relation":{"retraction":[{"id-type":"doi","id":"10.1007\/s00404-021-06152-1","asserted-by":"object"}]},"ISSN":["0932-0067","1432-0711"],"issn-type":[{"value":"0932-0067","type":"print"},{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,5]]},"assertion":[{"value":"16 March 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2020","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Clarification","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Editor\u2019s Note: The Editor-in-Chief is currently investigating this article\n                    (El-refaie et al., 2016) as concerns have been raised about the integrity of the\n                    data. There is also an ongoing investigation by the University of Mansoura.\n                    Further editorial action will be taken as appropriate once the investigation\n                    into the concerns is complete and all parties have been given an opportunity to\n                    respond in full.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2021","order":7,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":8,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":9,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00404-021-06152-1","URL":"https:\/\/doi.org\/10.1007\/s00404-021-06152-1","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}}]}}