{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:50:52Z","timestamp":1759942252517},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T00:00:00Z","timestamp":1448841600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1007\/s00404-015-3971-z","type":"journal-article","created":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T04:27:50Z","timestamp":1448857670000},"page":"251-259","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["New osseous soft markers for trisomy 13, 18 and 21"],"prefix":"10.1007","volume":"294","author":[{"given":"Annika","family":"Achter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Fimmers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Gembruch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette M.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,11,30]]},"reference":[{"issue":"3","key":"3971_CR1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/uog.12364","volume":"41","author":"M Agathokleous","year":"2013","unstructured":"Agathokleous M, Chaveeva P, Poon LC, Kosinski P, Nicolaides KH (2013) Meta-analysis of second-trimester markers for trisomy 21. Ultrasound Obstet Gynecol 41(3):247\u2013261","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"7","key":"3971_CR2","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1002\/pd.4139","volume":"33","author":"P Benn","year":"2013","unstructured":"Benn P, Borell A, Chiu R, Cuckle H, Dugoff L, Faas B, Gross S, Johnson J, Maymon R, Norton M, Odibo A, Schielen P, Spencer K, Huang T, Wright D, Yaron Y (2013) Position statement from the Aneuploidy Screening Committee on behalf of the Board of the International Society for Prenatal Diagnosis. Prenat Diagn 33(7):622\u2013629. doi: 10.1002\/pd.4139 (Epub 2013 May 21)","journal-title":"Prenat Diagn"},{"issue":"1","key":"3971_CR3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/uog.5334","volume":"32","author":"M Borenstein","year":"2008","unstructured":"Borenstein M, Persico N, Kagan KO, Gazzoni A, Nicolaides KH (2008) Frontomaxillary facial angle in screening for trisomy 21 at 11\u00a0+\u00a00 to 13\u00a0+\u00a06 weeks. Ultrasound Obstet Gynecol 32(1):5\u201311","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"9294","key":"3971_CR4","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/S0140-6736(01)06709-5","volume":"358","author":"S Cicero","year":"2001","unstructured":"Cicero S, Curcio P, Papageorghiou A, Sonek J, Nicolaides K (2001) Absence of nasal bone in fetuses with trisomy 21 at 11\u201314\u00a0weeks of gestation: an observational study. Lancet 358(9294):1665\u20131667","journal-title":"Lancet"},{"issue":"1","key":"3971_CR5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/uog.19","volume":"21","author":"S Cicero","year":"2003","unstructured":"Cicero S, Sonek JD, McKenna DS, Croom CS, Johnson L, Nicolaides KH (2003) Nasal bone hypoplasia in trisomy 21 at 15\u201322\u00a0weeks\u2019 gestation. Ultrasound Obstet Gynecol 21(1):15\u201318","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"3971_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2350\/12-04-1186-OA.1","volume":"16","author":"E Doberentz","year":"2013","unstructured":"Doberentz E, Schumacher R, Gembruch U, Gasser JA, M\u00fcller AM (2013) Coronal vertebral clefts: a radiological indicator for chromosomal aberrations. Pediatr Dev Pathol 16(1):1\u20136","journal-title":"Pediatr Dev Pathol"},{"issue":"2","key":"3971_CR7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1148\/radiology.167.2.2965816","volume":"167","author":"DK Edwards 3rd","year":"1988","unstructured":"Edwards DK 3rd, Berry CC, Hilton SW (1988) Trisomy 21 in newborn infants: chest radiographic diagnosis. Radiology 167(2):317\u2013318","journal-title":"Radiology"},{"issue":"2","key":"3971_CR8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/uog.7477","volume":"35","author":"W Lee","year":"2010","unstructured":"Lee W, Balasubramaniam M, Yeo L, Hassan SS, Gotsch F, Kusanovic JP, Gon\u00e7alves LF, Romero R (2010) Iliac crest angle: a novel sonographic parameter for the prediction of Down syndrome risk during the second trimester of pregnancy. Ultrasound Obstet Gynecol 35(2):163\u2013171","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"6","key":"3971_CR9","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/uog.1074","volume":"23","author":"R Maymon","year":"2004","unstructured":"Maymon R, Tovbin Y, Dreazen E, Weinraub Z, Herman A (2004) All five digits of the hands of fetuses with down syndrome are short. Ultrasound Obstet Gynecol 23(6):557\u2013560","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"3","key":"3971_CR10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/pd.4047","volume":"33","author":"K Narasimhan","year":"2013","unstructured":"Narasimhan K, Lin SL, Tong T, Baig S, Ho S, Sukumar P, Biswas A, Hahn S, Bajic VB, Choolani M (2013) Maternal serum protein profile and immune response protein subunits as markers for non-invasive prenatal diagnosis of trisomy 21, 18, and 13. Prenat Diagn 33(3):223\u2013231","journal-title":"Prenat Diagn"},{"issue":"17","key":"3971_CR11","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1056\/NEJMoa1407349","volume":"372","author":"ME Norton","year":"2015","unstructured":"Norton ME, Jacobsson B, Swamy GK, Laurent LC, Ranzini AC, Brar H, Tomlinson MW, Pereira L, Spitz JL, Hollemon D, Cuckle H, Musci TJ, Wapner RJ (2015) Cell-free DNA analysis for noninvasive examination of trisomy. N Engl J Med 372(17):1589\u20131597. doi: 10.1056\/NEJMoa1407349 (Epub 2015 Apr 1)","journal-title":"N Engl J Med"},{"issue":"7","key":"3971_CR12","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.7863\/jum.2011.30.7.1009","volume":"30","author":"KJ Rice","year":"2011","unstructured":"Rice KJ, Ballas J, Lai E, Hartney C, Jones MC, Pretorius DH (2011) Diagnosis of fetal limb abnormalities before 15\u00a0weeks: cause for concern. J Ultrasound Med 30(7):1009\u20131019","journal-title":"J Ultrasound Med"},{"issue":"1","key":"3971_CR13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00404-007-0421-6","volume":"277","author":"NC Sayin","year":"2008","unstructured":"Sayin NC, Canda MT, Ahmet N, Arda S, S\u00fct N, Varol FG (2008) The association of triple-marker test results with adverse pregnancy outcomes in low-risk pregnancies with healthy newborns. Arch Gynecol Obstet 277(1):47\u201353","journal-title":"Arch Gynecol Obstet"},{"key":"3971_CR14","doi-asserted-by":"crossref","first-page":"212S","DOI":"10.1007\/978-3-642-03560-9","volume-title":"Fetal radiology: a diagnostic atlas; with 113 figures and 238 individual illustrations and 51 tables","author":"R Schumacher","year":"2010","unstructured":"Schumacher R, Seaver LH, Spanger J (2010) Fetal radiology: a diagnostic atlas; with 113 figures and 238 individual illustrations and 51 tables, 2nd edn. Springer, Berlin, Heidelberg, p 212S","edition":"2"},{"issue":"6","key":"3971_CR15","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/s00404-010-1527-9","volume":"283","author":"N Unsal","year":"2011","unstructured":"Unsal N, Ozat M, Kanat-Pektas M, Gungor T, Danisman N (2011) The significance of fetal maxillary length in the first trimester screening for trisomy 21. Arch Gynecol Obstet 283(6):1199\u20131205","journal-title":"Arch Gynecol Obstet"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-015-3971-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00404-015-3971-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-015-3971-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T18:00:41Z","timestamp":1559066441000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00404-015-3971-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,30]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["3971"],"URL":"https:\/\/doi.org\/10.1007\/s00404-015-3971-z","relation":{},"ISSN":["0932-0067","1432-0711"],"issn-type":[{"value":"0932-0067","type":"print"},{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,30]]}}}