{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T07:56:24Z","timestamp":1784447784040,"version":"3.55.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T00:00:00Z","timestamp":1536364800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1007\/s00404-018-4880-8","type":"journal-article","created":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T03:32:02Z","timestamp":1536377522000},"page":"951-959","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Seroma in breast surgery: all the surgeons fault?"],"prefix":"10.1007","volume":"298","author":[{"given":"Florian","family":"Ebner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W. P.","family":"Friedl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelie","family":"de Gregorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztian","family":"Lato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inga","family":"Bekes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Janni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0037-127X","authenticated-orcid":false,"given":"Nikolaus","family":"de Gregorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,9,8]]},"reference":[{"issue":"1","key":"4880_CR1","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1007\/BF00348194","volume":"18","author":"U Veronesi","year":"1991","unstructured":"Veronesi U, Luini A, Galimberti V, Zurrida S (1991) Conservation approaches for the management of stage I\/II carcinoma of the breast: Milan Cancer Institute trials. World J Surg 18(1):70\u201375","journal-title":"World J Surg"},{"issue":"10","key":"4880_CR2","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1001\/jamasurg.2014.1076","volume":"149","author":"NB Abt","year":"2014","unstructured":"Abt NB, Flores JM, Baltodano PA, Sarhane KA, Abreu FM, Cooney CM et al (2014) Neoadjuvant chemotherapy and short-term morbidity in patients undergoing mastectomy with and without breast reconstruction. JAMA Surg 149(10):1068\u20131076","journal-title":"JAMA Surg"},{"issue":"10","key":"4880_CR3","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1007\/s00066-013-0437-8","volume":"189","author":"F Sedlmayer","year":"2013","unstructured":"Sedlmayer F, Sautter-Bihl M-L, Budach W, Dunst J, Fastner G, Feyer P et al (2013) DEGRO practical guidelines: radiotherapy of breast cancer I: radiotherapy following breast conserving therapy for invasive breast cancer. Strahlenther Onkol 189(10):825\u2013833","journal-title":"Strahlenther Onkol"},{"issue":"1","key":"4880_CR4","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.jamcollsurg.2008.08.029","volume":"208","author":"SY Boostrom","year":"2009","unstructured":"Boostrom SY, Throckmorton AD, Boughey JC, Holifield AC, Zakaria S, Hoskin TL et al (2009) Incidence of clinically significant seroma after breast and axillary surgery. J Am Coll Surg 208(1):148\u2013150","journal-title":"J Am Coll Surg"},{"issue":"12","key":"4880_CR5","doi-asserted-by":"publisher","first-page":"3793","DOI":"10.1245\/s10434-014-3999-5","volume":"21","author":"MJ Silverstein","year":"2014","unstructured":"Silverstein MJ, Fastner G, Maluta S, Reitsamer R, Goer DA, Vicini F et al (2014) Intraoperative radiation therapy: a critical analysis of the ELIOT and TARGIT trials. Part 2\u2013TARGIT. Ann Surg Oncol 21(12):3793\u20133799","journal-title":"Ann Surg Oncol"},{"issue":"14","key":"4880_CR6","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1200\/JCO.2014.55.1572","volume":"32","author":"TA Buchholz","year":"2014","unstructured":"Buchholz TA, Somerfield MR, Griggs JJ, El-Eid S, Hammond MEH, Lyman GH et al (2014) Margins for breast-conserving surgery with whole-breast irradiation in stage I and II invasive breast cancer: American Society of Clinical Oncology endorsement of the Society of Surgical Oncology\/American Society for Radiation Oncology consensus guideline. J Clin Oncol 32(14):1502\u20131506","journal-title":"J Clin Oncol"},{"issue":"7","key":"4880_CR7","first-page":"32","volume":"2012","author":"R Kreienberg","year":"2012","unstructured":"Kreienberg R, Kopp I, Albert U-S, Bartsch HH, Beckmann MW, Berg D et al (2012) Interdisziplin\u00e4re S3-Leitlinie und Nachsorge des Leitlinie. Ger Cancer Soc 2012(7):32\u201345","journal-title":"Ger Cancer Soc"},{"issue":"4","key":"4880_CR8","doi-asserted-by":"publisher","first-page":"373","DOI":"10.4048\/jbc.2012.15.4.373","volume":"15","author":"V Srivastava","year":"2012","unstructured":"Srivastava V, Basu S, Shukla VK (2012) Seroma formation after breast cancer surgery: what we have learned in the last two decades. J Breast Cancer 15(4):373\u2013380","journal-title":"J Breast Cancer"},{"issue":"4","key":"4880_CR9","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1093\/jjco\/hyl019","volume":"36","author":"K Kuroi","year":"2006","unstructured":"Kuroi K, Shimozuma K, Taguchi T, Imai H, Yamashiro H, Ohsumi S et al (2006) Evidence-based risk factors for seroma formation in breast surgery. Jpn J Clin Oncol 36(4):197\u2013206","journal-title":"Jpn J Clin Oncol"},{"issue":"19","key":"4880_CR10","doi-asserted-by":"publisher","first-page":"4312","DOI":"10.1200\/JCO.2005.03.228","volume":"23","author":"AD Purushotham","year":"2005","unstructured":"Purushotham AD, Upponi S, Klevesath MB, Bobrow L, Millar K, Myles JP et al (2005) Morbidity after sentinel lymph node biopsy in primary breast cancer: results from a randomized controlled trial. J Clin Oncol 23(19):4312\u20134321","journal-title":"J Clin Oncol"},{"issue":"11","key":"4880_CR11","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1055\/s-0033-1351071","volume":"73","author":"FK Ebner","year":"2013","unstructured":"Ebner FK, Friedl TWP, Reich A, Janni W, Rempen A, Degregorio N et al (2013) Does non-placement of a drain in breast surgery increase the rate of complications and revisions? Geburtshilfe Frauenheilkd 73(11):1128\u20131134","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"3","key":"4880_CR12","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1159\/000341102","volume":"7","author":"J-R Garbay","year":"2012","unstructured":"Garbay J-R, Thoury A, Moinon E, Cavalcanti A, Di Palma M, Karsenti G et al (2012) Axillary padding without drainage after axillary lymphadenectomy\u2014a prospective study of 299 patients with early breast cancer. Breast Care (Basel) 7(3):231\u2013235","journal-title":"Breast Care (Basel)"},{"key":"4880_CR13","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.ejso.2012.12.022","volume":"39","author":"JC Taylor","year":"2013","unstructured":"Taylor JC, Rai S, Hoar F, Brown H, Vishwanath L (2013) Breast cancer surgery without suction drainage: the impact of adopting a \u201cno drains\u201d policy on symptomatic seroma formation rates. Eur J Surg Oncol 39:334\u2013338","journal-title":"Eur J Surg Oncol"},{"key":"4880_CR14","volume-title":"Drainage tube placement after lymph gland removal from the armpit for breast cancer","author":"DR Thomson","year":"2013","unstructured":"Thomson DR, Sadideen H, Furniss D (2013) Drainage tube placement after lymph gland removal from the armpit for breast cancer. Wiley, New York"},{"key":"4880_CR15","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1016\/j.ejca.2012.09.010","volume":"49","author":"A Glechner","year":"2013","unstructured":"Glechner A, W\u00f6ckel A, Gartlehner G, Thaler K, Strobelberger M, Griebler U et al (2013) Sentinel lymph node dissection only versus complete axillary lymph node dissection in early invasive breast cancer: a systematic review and meta-analysis. Eur J Cancer 49:812\u2013825","journal-title":"Eur J Cancer"},{"key":"4880_CR16","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s10549-015-3549-2","volume":"153","author":"DP Joyce","year":"2015","unstructured":"Joyce DP, Manning A, Carter M, Hill ADK, Kell MR, Barry M (2015) Meta-analysis to determine the clinical impact of axillary lymph node dissection in the treatment of invasive breast cancer. Breast Cancer Res Treat 153:235\u2013240","journal-title":"Breast Cancer Res Treat"},{"issue":"4","key":"4880_CR17","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1177\/107327481201900403","volume":"19","author":"M Shah-Khan","year":"2012","unstructured":"Shah-Khan M, Boughey JC (2012) Evolution of axillary nodal staging in breast cancer: clinical implications of the ACOSOG Z0011 trial. Cancer Control 19(4):267\u2013276","journal-title":"Cancer Control"},{"issue":"14","key":"4880_CR18","first-page":"244","volume":"111","author":"W Janni","year":"2014","unstructured":"Janni W, K\u00fchn T, Schwentner L, Kreienberg R, Fehm T, W\u00f6ckel A (2014) Sentinel node biopsy and axillary dissection in breast cancer: the evidence and its limits. Dtsch Arztebl Int 111(14):244\u2013249","journal-title":"Dtsch Arztebl Int"},{"key":"4880_CR19","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1007\/s00432-017-2425-3","volume":"143","author":"F Ebner","year":"2017","unstructured":"Ebner F, W\u00f6ckel A, Janni W, Kreienberg R, Schwentner L, Wischnewsky M (2017) Personalized axillary dissection: the number of excised lymph nodes of nodal-positive breast cancer patients has no significant impact on relapse-free and overall survival. J Cancer Res Clin Oncol 143:1823\u20131831","journal-title":"J Cancer Res Clin Oncol"},{"issue":"12","key":"4880_CR20","doi-asserted-by":"publisher","first-page":"1825","DOI":"10.1038\/bjc.2011.470","volume":"105","author":"A Balakrishnan","year":"2011","unstructured":"Balakrishnan A, Ravichandran D (2011) Early operable breast cancer in elderly women treated with an aromatase inhibitor letrozole as sole therapy. Br J Cancer 105(12):1825\u20131829","journal-title":"Br J Cancer"},{"issue":"2","key":"4880_CR21","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1524-4741.2011.01203.x","volume":"18","author":"U Hille","year":"2002","unstructured":"Hille U, Soergel P, L\u00e4nger F, Schippert C, Makowski L, Hillemanns P (2002) Aromatase inhibitors as solely treatment in postmenopausal breast cancer patients. Breast J 18(2):145\u2013150","journal-title":"Breast J"},{"issue":"7","key":"4880_CR22","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1038\/sj.bjc.6603600","volume":"96","author":"D Hind","year":"2007","unstructured":"Hind D, Wyld L, Reed MW (2007) Surgery, with or without tamoxifen, vs tamoxifen alone for older women with operable breast cancer: Cochrane review. Br J Cancer 96(7):1025\u20131029","journal-title":"Br J Cancer"},{"issue":"5","key":"4880_CR23","doi-asserted-by":"publisher","first-page":"863","DOI":"10.3892\/mco.2016.778","volume":"4","author":"H Headon","year":"2016","unstructured":"Headon H, Wazir U, Kasem A, Mokbel K (2016) Surgical treatment of the primary tumour improves the overall survival in patients with metastatic breast cancer: a systematic review and meta-analysis. Mol Clin Oncol 4(5):863\u2013867","journal-title":"Mol Clin Oncol"},{"issue":"8","key":"4880_CR24","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.ijsu.2011.08.002","volume":"9","author":"T Cortadellas","year":"2011","unstructured":"Cortadellas T, C\u00f3rdoba O, Espinosa-Bravo M, Mendoza-Santin C, Rodr\u00edguez-Fern\u00e1ndez J, Esgueva A et al (2011) Electrothermal bipolar vessel sealing system in axillary dissection: a prospective randomized clinical study. Int J Surg 9(8):636\u2013640","journal-title":"Int J Surg"},{"issue":"6","key":"4880_CR25","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1001\/archsurg.143.6.575","volume":"143","author":"A Manouras","year":"2008","unstructured":"Manouras A, Markogiannakis H, Genetzakis M, Filippakis GM, Lagoudianakis EE, Kafiri G et al (2008) Modified radical mastectomy with axillary dissection using the electrothermal bipolar vessel sealing system. Arch Surg. 143(6):575\u2013580 (discussion 581)","journal-title":"Arch Surg."},{"issue":"6","key":"4880_CR26","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.breast.2012.08.003","volume":"21","author":"L Nespoli","year":"2012","unstructured":"Nespoli L, Antolini L, Stucchi C, Nespoli A, Valsecchi MG, Gianotti L (2012) Axillary lymphadenectomy for breast cancer. A randomized controlled trial comparing a bipolar vessel sealing system to the conventional technique. Breast 21(6):739\u2013745","journal-title":"Breast"},{"issue":"1","key":"4880_CR27","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/S0748-7983(97)80135-7","volume":"23","author":"G Canavese","year":"1997","unstructured":"Canavese G, Catturich A, Vecchio C, Gipponi M, Tomei D, Sertoli MR et al (1997) Surgical complications related to peri-operative adjuvant chemotherapy in breast cancer. Results of a prospective, controlled, randomized clinical trial. Eur J Surg Oncol 23(1):10\u201312","journal-title":"Eur J Surg Oncol"},{"issue":"4","key":"4880_CR28","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1016\/j.ijrobp.2009.06.008","volume":"77","author":"U Kraus-Tiefenbacher","year":"2010","unstructured":"Kraus-Tiefenbacher U, Welzel G, Brade J, Hermann B, Siebenlist K, Wasser KS et al (2010) Postoperative seroma formation after intraoperative radiotherapy using low-kilovoltage X-rays given during breast-conserving surgery. Int J Radiat Oncol Biol Phys 77(4):1140\u20131145","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4880_CR29","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/1748-717X-8-95","volume":"8","author":"B Tuschy","year":"2013","unstructured":"Tuschy B, Berlit S, Romero S, Sperk E, Wenz F, Kehl S et al (2013) Clinical aspects of intraoperative radiotherapy in early breast cancer: short-term complications after IORT in women treated with low energy X-rays. Radiat Oncol 8:95","journal-title":"Radiat Oncol"},{"key":"4880_CR30","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1007\/s00404-016-4124-8","volume":"294","author":"F Ebner","year":"2016","unstructured":"Ebner F, Schramm A, Bottke D, Friedl TW, Wiegel T, Fink V et al (2016) Comparison of seroma production in breast conserving surgery with or without intraoperative radiotherapy as tumour bed boost. Arch Gynecol Obstet 294:861\u2013866","journal-title":"Arch Gynecol Obstet"},{"issue":"3","key":"4880_CR31","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1111\/tbj.12402","volume":"21","author":"S Cracco","year":"2015","unstructured":"Cracco S, Semprini G, Cattin F, Gregoraci G, Zeppieri M, Isola M et al (2015) Impact of intraoperative radiotherapy on cosmetic outcome and complications after oncoplastic breast surgery. Breast J 21(3):285\u2013290","journal-title":"Breast J"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00404-018-4880-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-018-4880-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-018-4880-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T19:26:03Z","timestamp":1567884363000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00404-018-4880-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,8]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["4880"],"URL":"https:\/\/doi.org\/10.1007\/s00404-018-4880-8","relation":{},"ISSN":["0932-0067","1432-0711"],"issn-type":[{"value":"0932-0067","type":"print"},{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,8]]},"assertion":[{"value":"6 September 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declare that they have no potential conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the local ethic committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}