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Search terms included COVID-19, SARS-CoV-2, pregnant women, infants, and vertical transmission.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 230 women with COVID-19 (154 deliveries, 66 ongoing pregnancies, and 10 abortions) and 156 newborns from 20 eligible studies were included in this systematic review. A total of 34.62% of the pregnant patients had obstetric complications, and 59.05% of patients displayed fever. Lymphopenia was observed in 40.71% of patients. A total of 5.19% of women received mechanical ventilation. Seven women were critically ill. One mother and two newborns died. A total of 24.74% of newborns were premature. Five newborns\u2019 throat swab tests of SARS-CoV-2 were positive, all of which were delivered by cesarean section. For eight newborns with negative throat swab tests, three had both elevated IgM and IgG against SARS-CoV-2. Nucleic acid tests of vaginal secretions, breast milk, amniotic fluid, placental blood, and placental tissues were negative.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Most pregnant patients were mildly ill. The mortality of pregnant women with COVID-19 was lower than that of overall COVID-19 patients. Cesarean section was more common than vaginal delivery for pregnant women with COVID-19. Premature delivery was the main adverse event for newborns. The vertical transmission rate calculated by SARS-CoV-2 nucleic acid tests was 3.91%. Serum antibodies against SARS-CoV-2 should be tested more frequently, and multiple samples should be included in pathogenic testing.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00404-020-05889-5","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T15:03:10Z","timestamp":1606834990000},"page":"337-345","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["Clinical characteristics and outcomes of pregnant women with COVID-19 and the risk of vertical transmission: a systematic review"],"prefix":"10.1007","volume":"303","author":[{"given":"Jianhua","family":"Chi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjian","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9448-3423","authenticated-orcid":false,"given":"Qinglei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,12,1]]},"reference":[{"key":"5889_CR1","doi-asserted-by":"publisher","first-page":"E003","DOI":"10.3760\/cma.j.issn.0253-2727.2020.0003","volume":"41","author":"T Wu","year":"2020","unstructured":"Wu T, Kang SC, Feng W, Fu H, Zhu XH, Wang XJ, Dai PJ, Wang TH, Bai H, Xi R, Zhang Q, Xue X, Xiang DW (2020) Biological characters analysis of COVID-19 patient accompanied with aplastic anemia. 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