{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T01:58:20Z","timestamp":1767664700754,"version":"3.37.3"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Innsbruck and Medical University of Innsbruck"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The aim of the present study was to assess the impact of postponed screening examinations and lockdown measures on gynecological and breast cancer diagnoses throughout the year 2020 in a gynecological oncological center in Austria.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Data of 889 patients with either newly diagnosed gynecological or breast cancer between January 2019 and December 2020 were collected. Clinical parameters including symptoms, performance status, comorbidities and referral status were compared in patients, who were newly diagnosed with cancer in the period of the first lockdown from March 2020 to April 2020 and the second lockdown from November 2020 to December 2020 and compared to the same period in 2019.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Our results showed a strong decline in newly diagnosed cancers during the lockdown periods: \u221245% in gynecological cancer and -52% in breast cancer compared to the same period in 2019. Compared to the analogue period of 2019, breast cancer patients reported significantly more tumor-associated symptoms (55% vs. 31%, <jats:italic>p<\/jats:italic>\u2009=\u20090.013) during and in between (48% vs. 32%, <jats:italic>p<\/jats:italic>\u2009=\u20090.022) the lockdowns. During the lockdown, periods in the group of breast cancer patients\u2019 tumor stage varied significantly compared to 2019 (T2\u2013T4; <jats:italic>p<\/jats:italic>\u2009=\u20090.047).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Both lockdowns led to a strong decrease in newly diagnosed gynecological and breast cancers. Treatment delays in potentially curable disease could lead to inferior clinical outcomes, with the risk of missing the optimal treatment window. As the COVID-19 pandemic will be a challenge for some time to come, new strategies in patient care are needed to optimize cancer screening and management during the pandemic.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00404-021-06259-5","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T10:48:42Z","timestamp":1632480522000},"page":"945-953","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The impact of COVID-19 pandemic on the rate of newly diagnosed gynecological and breast cancers: a tertiary center perspective"],"prefix":"10.1007","volume":"305","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2972-3099","authenticated-orcid":false,"given":"Katharina","family":"Knoll","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7952-1284","authenticated-orcid":false,"given":"Elisabeth","family":"Reiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9572-9114","authenticated-orcid":false,"given":"Katharina","family":"Leitner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0536-2372","authenticated-orcid":false,"given":"Johanna","family":"K\u00f6gl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2033-6228","authenticated-orcid":false,"given":"Christoph","family":"Ebner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8965-9981","authenticated-orcid":false,"given":"Christian","family":"Marth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6795-3015","authenticated-orcid":false,"given":"Irina","family":"Tsibulak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"6259_CR1","unstructured":"John Hopkins University and Medicine (2020) COVID-19 Map\u2014Johns Hopkins Coronavirus Resource Center. 2020 [cited 26 Jan 2021]. https:\/\/coronavirus.jhu.edu\/map.html."},{"key":"6259_CR2","unstructured":"Federal Ministry of Social Affairs, Healthcare and Consumer Protection, Republic of Austria (2020) Official COVID19 Dashboard (Public Information): hospitalisation [cited 26 Jan 2021]. https:\/\/info.gesundheitsministerium.at\/dashboard_Hosp.html?l=de."},{"issue":"11","key":"6259_CR3","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1136\/ijgc-2020-001975","volume":"30","author":"I Tsibulak","year":"2020","unstructured":"Tsibulak I, Reiser E, Bogner G, Petru E, Hell-Teutsch J, Reinthaller A et al (2020) Decrease in gynecological cancer diagnoses during the COVID-19 pandemic: an Austrian perspective. 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