{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:53:19Z","timestamp":1787161999506,"version":"build-2736575974"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002839","name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002839","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lymphedema is a frequent complication after surgical treatment in gynecological oncology with substantial impact on patients\u00b4 Quality of Life (QoL). Little is known about screening instruments and prevention. Primary objective was to develop and validate the German version of a 13 items screening questionnaire (SQ) developed by Yost et al. to provide a valid instrument for early diagnosis of lower extremity lymphedema (LEL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>After translation the SQ was used in pt. with cervical or endometrial cancer who underwent pelvic\/paraaortic Lymphadenectomy. Sensitivity and specifity were analysed regarding possible prediction and influencing factors of LEL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      67 pt. had LEL (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009128). Nearly 50% of women in each group (38 in LEL\u2009+\u2009e 30 in LEL \u2212\u00a0) had a body mass index (BMI)\u2009&gt; 30\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Number of removed lymphnodes, radiotherapy and were significantly associated with development of LEL. Translated Mayo Clinic questionnaire can be used with reliable specifity and sensitivity. Four additional questions improved the diagnostic accuracy of the SQ.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The translated SQ is a valuable and predictive tool for screening and early detection of LEL in Gynecological cancer surgery and can even improved by adding simple questions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-022-06779-8","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T01:07:40Z","timestamp":1665536860000},"page":"1557-1565","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Lymphedema after pelvic and para-aortic lymphadenectomy\u2014results of a systematic evaluation in patients with cervical and endometrial carcinoma"],"prefix":"10.1007","volume":"307","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8606-6523","authenticated-orcid":false,"given":"R.","family":"Armbrust","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Auletta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Cichon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Vercellino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Yost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Sehouli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,12]]},"reference":[{"key":"6779_CR1","volume-title":"Textbook of lympohology","author":"M F\u00f6ldi","year":"2003","unstructured":"F\u00f6ldi M, F\u00f6ldi EKS (2003) Textbook of lympohology. Elsevier, Munich"},{"issue":"2","key":"6779_CR2","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1046\/j.0004-8666.2003.00040.x","volume":"43","author":"M Ryan","year":"2003","unstructured":"Ryan M et al (2003) Aetiology and prevalence of lower limb lymphoedema following treatment for gynaecological cancer. Aust N Z J Obstet Gynaecol 43(2):148\u2013151","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"10","key":"6779_CR3","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1093\/qjmed\/hcg126","volume":"96","author":"CJ Moffatt","year":"2003","unstructured":"Moffatt CJ et al (2003) Lymphoedema: an underestimated health problem. QJM 96(10):731\u2013738","journal-title":"QJM"},{"key":"6779_CR4","doi-asserted-by":"crossref","unstructured":"Neuh\u00fcttler E, Brenner. 2003 Beitrag zur Epidemiologie des Lymph\u00f6dems","DOI":"10.1007\/978-3-7091-6723-6_3"},{"issue":"3","key":"6779_CR5","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/j.ygyno.2017.06.004","volume":"146","author":"SC Hayes","year":"2017","unstructured":"Hayes SC et al (2017) Lymphedema following gynecological cancer: Results from a prospective, longitudinal cohort study on prevalence, incidence and risk factors. Gynecol Oncol 146(3):623\u2013629","journal-title":"Gynecol Oncol"},{"issue":"12","key":"6779_CR6","doi-asserted-by":"publisher","first-page":"2607","DOI":"10.1002\/cncr.22684","volume":"109","author":"V Beesley","year":"2007","unstructured":"Beesley V et al (2007) Lymphedema after gynecological cancer treatment\u202f: prevalence, correlates, and supportive care needs. Cancer 109(12):2607\u20132614","journal-title":"Cancer"},{"issue":"4","key":"6779_CR7","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3109\/02844319409022014","volume":"28","author":"M Werngren-Elgstr\u00f6m","year":"1994","unstructured":"Werngren-Elgstr\u00f6m M, Lidman D (1994) Lymphoedema of the lower extremities after surgery and radiotherapy for cancer of the cervix. Scand J Plast Reconstr Surg Hand Surg 28(4):289\u2013293","journal-title":"Scand J Plast Reconstr Surg Hand Surg"},{"issue":"1","key":"6779_CR8","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2016.27.e4","volume":"27","author":"D Mitra","year":"2016","unstructured":"Mitra D et al (2016) The risk of lymphedema after postoperative radiation therapy in endometrial cancer. J Gynecol Oncol 27(1):e4","journal-title":"J Gynecol Oncol"},{"issue":"2","key":"6779_CR9","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.ygyno.2015.09.007","volume":"139","author":"H Yamazaki","year":"2015","unstructured":"Yamazaki H et al (2015) Relationship between removal of circumflex iliac nodes distal to the external iliac nodes and postoperative lower-extremity lymphedema in uterine cervical cancer. Gynecol Oncol 139(2):295\u2013299","journal-title":"Gynecol Oncol"},{"issue":"3","key":"6779_CR10","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/S1053-4296(03)00038-9","volume":"13","author":"AL Cheville","year":"2003","unstructured":"Cheville AL et al (2003) The grading of lymphedema in oncology clinical trials. Semin Radiat Oncol 13(3):214\u2013225","journal-title":"Semin Radiat Oncol"},{"issue":"3","key":"6779_CR11","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1586\/erp.11.30","volume":"11","author":"A Finnane","year":"2011","unstructured":"Finnane A et al (2011) Quality of life of women with lower-limb lymphedema following gynecological cancer. Expert Rev Pharmacoecon Outcomes Res 11(3):287\u2013297","journal-title":"Expert Rev Pharmacoecon Outcomes Res"},{"issue":"1","key":"6779_CR12","first-page":"99","volume":"11","author":"M Boris","year":"1997","unstructured":"Boris M, Weindorf S, Lasinkski S (1997) Persistence of lymphedema reduction after noninvasive complex lymphedema therapy. Oncology 11(1):99\u2013109","journal-title":"Oncology"},{"issue":"5","key":"6779_CR13","doi-asserted-by":"publisher","first-page":"694","DOI":"10.2522\/ptj.20120088","volume":"93","author":"KJ Yost","year":"2013","unstructured":"Yost KJ et al (2013) Development and validation of a self-report lower-extremity lymphedema screening questionnaire in women. Phys Ther 93(5):694\u2013703","journal-title":"Phys Ther"},{"issue":"22","key":"6779_CR14","doi-asserted-by":"publisher","first-page":"5138","DOI":"10.1002\/cncr.25458","volume":"116","author":"JN Cormier","year":"2010","unstructured":"Cormier JN et al (2010) Lymphedema beyond breast cancer: a systematic review and meta-analysis of cancer-related secondary lymphedema. Cancer 116(22):5138\u20135149","journal-title":"Cancer"},{"issue":"3c","key":"6779_CR15","first-page":"2235","volume":"18","author":"H Sch\u00fcnemann","year":"1998","unstructured":"Sch\u00fcnemann H, Willich N (1998) Lymphoedema of the arm after primary treatment of breast cancer. Anticancer Res 18(3c):2235\u20132236","journal-title":"Anticancer Res"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-022-06779-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-022-06779-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-022-06779-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T13:08:24Z","timestamp":1681736904000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-022-06779-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,12]]},"references-count":15,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["6779"],"URL":"https:\/\/doi.org\/10.1007\/s00404-022-06779-8","relation":{},"ISSN":["1432-0711"],"issn-type":[{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,12]]},"assertion":[{"value":"6 March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institutional review board statement"}},{"value":"Written informed consent has been obtained from the patient(s) to publish this paper\u201d if applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent statement"}}]}}