{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:38:49Z","timestamp":1740109129860,"version":"3.37.3"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100007210","name":"RWTH Aachen University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007210","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Right ventricular (RV) function influences the outcome of hypoplastic left heart (HLH) patients. This study aimed to confirm the assumption of prenatal RV remodeling and possible influencing factors of myocardial restructuring using two-dimensional speckle tracking echocardiography (2D STE).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This is a retrospective cross-sectional cohort study including HLH fetuses and gestational age-matched controls. Based on a four-chamber view, cine loops were stored with 60 frames per second. Global longitudinal peak systolic strain (GLPSS) of the RV was retrospectively determined and compared to healthy controls. Furthermore, HLH subgroups were built according to the presence of left ventricular endocardial fibroelastosis (LV-EFE) and restrictive foramen ovale (FO) to investigate the effect of these compromising factors on myocardial deformation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 41 HLH fetuses and 101 controls were included. Gestational age at fetal assessment was similarly distributed in both groups (controls: 26.0\u2009\u00b1\u20095.6\u00a0weeks vs. HLH: 29.1\u2009\u00b1\u20095.6\u00a0weeks). Relating to RV-GLPSS values, fetuses with HLH demonstrated lower mean values than healthy control fetuses (\u2212\u200915.65% vs.\u2009\u2212\u200916.80%, <jats:italic>p<\/jats:italic>\u2009=\u20090.065). Cases with LV-EFE (<jats:italic>n<\/jats:italic>\u2009=\u200911) showed significantly lower mean values compared to such without LV-EFE (<jats:italic>n<\/jats:italic>\u2009=\u200930) (RV-GLPSS:\u2009\u2212\u200912.12% vs.\u2009\u2212\u200916.52%, <jats:italic>p<\/jats:italic>\u2009=\u20090.003). No significant differences were observed for cases with FO restriction (<jats:italic>n<\/jats:italic>\u2009=\u200910).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In HLH the RV undergoes prenatal remodeling, leading to an adaptation of myocardial function to LV conditions. Further explorations by STE should expand knowledge about RV contraction properties in HLH and its impact on surgical outcome.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00404-022-06857-x","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T14:55:03Z","timestamp":1676040903000},"page":"699-708","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of right ventricular myocardial deformation properties in fetal hypoplastic left heart by two-dimensional speckle tracking echocardiography"],"prefix":"10.1007","volume":"307","author":[{"given":"Christian","family":"Enzensberger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3732-7464","authenticated-orcid":false,"given":"Oliver","family":"Graupner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Meister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maleen","family":"Reitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malena","family":"G\u00f6tte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"Wolter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Herrmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Axt-Fliedner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"issue":"7","key":"6857_CR1","doi-asserted-by":"publisher","first-page":"E51","DOI":"10.1055\/s-0032-1312830","volume":"33","author":"R Axt-Fliedner","year":"2012","unstructured":"Axt-Fliedner R, Enzensberger C, Fass N, Vogel M, Kawecki A, Weichert J, Kohl T, Gembruch U, Germer U, Krapp M, Degenhardt J (2012) Fetal diagnosis of hypoplastic left heart, associations and outcomes in the current era. Ultraschall Med 33(7):E51\u2013E56. https:\/\/doi.org\/10.1055\/s-0032-1312830","journal-title":"Ultraschall Med"},{"issue":"1","key":"6857_CR2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/oxfordjournals.aje.a113979","volume":"121","author":"C Ferencz","year":"1985","unstructured":"Ferencz C, Rubin JD, McCarter RJ, Brenner JI, Neill CA, Perry LW, Hepner SI, Downing JW (1985) Congenital heart disease: prevalence at livebirth. The Baltimore-Washington Infant Study. Am J Epidemiol 121(1):31\u201336. https:\/\/doi.org\/10.1093\/oxfordjournals.aje.a113979","journal-title":"Am J Epidemiol"},{"issue":"2","key":"6857_CR3","first-page":"393","volume":"11","author":"DC Fyler","year":"1981","unstructured":"Fyler DC, Rothman KJ, Buckley LP, Cohn HE, Hellenbrand WE, Castaneda A (1981) The determinants of five year survival of infants with critical congenital heart disease. Cardiovasc Clin 11(2):393\u2013405","journal-title":"Cardiovasc Clin"},{"issue":"12","key":"6857_CR4","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1016\/s0735-1097(02)01886-7","volume":"39","author":"JI Hoffman","year":"2002","unstructured":"Hoffman JI, Kaplan S (2002) The incidence of congenital heart disease. J Am Coll Cardiol 39(12):1890\u20131900. https:\/\/doi.org\/10.1016\/s0735-1097(02)01886-7","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"6857_CR5","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.jtcvs.2009.07.063","volume":"139","author":"AK Furck","year":"2010","unstructured":"Furck AK, Uebing A, Hansen JH, Scheewe J, Jung O, Fischer G, Rickers C, Holland-Letz T, Kramer HH (2010) Outcome of the Norwood operation in patients with hypoplastic left heart syndrome: a 12-year single-center survey. J Thorac Cardiovasc Surg 139(2):359\u2013365. https:\/\/doi.org\/10.1016\/j.jtcvs.2009.07.063","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"8","key":"6857_CR6","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1055\/a-0828-7968","volume":"79","author":"O Graupner","year":"2019","unstructured":"Graupner O, Enzensberger C, Axt-Fliedner R (2019) New aspects in the diagnosis and therapy of fetal hypoplastic left heart syndrome. Geburtshilfe Frauenheilkd 79(8):863\u2013872. https:\/\/doi.org\/10.1055\/a-0828-7968","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"3","key":"6857_CR7","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1007\/s00246-017-1783-6","volume":"39","author":"SJ Zaidi","year":"2018","unstructured":"Zaidi SJ, Lefaiver CA, Muangmingsuk S, Cui VW, Roberson DA, Penk J (2018) Right ventricular longitudinal shortening before and after stage I surgical palliation correlates with outcomes. Pediatr Cardiol 39(3):526\u2013532. https:\/\/doi.org\/10.1007\/s00246-017-1783-6","journal-title":"Pediatr Cardiol"},{"issue":"4","key":"6857_CR8","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1055\/s-0043-111590","volume":"39","author":"O Graupner","year":"2018","unstructured":"Graupner O, Enzensberger C, Wieg L, Degenhardt J, Wolter A, Khalil M, Schranz D, Yerebakan C, Doelle A, Herrmann J, Axt-Fliedner R (2018) Endocardial fibroelastosis of the left ventricle affects right ventricular performance in fetuses with hypoplastic left heart syndrome: a prospective study using M-mode, PW- and tissue doppler techniques. Ultraschall Med 39(4):413\u2013421. https:\/\/doi.org\/10.1055\/s-0043-111590. (in English)","journal-title":"Ultraschall Med"},{"issue":"6","key":"6857_CR9","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1002\/uog.14940","volume":"47","author":"O Graupner","year":"2016","unstructured":"Graupner O, Enzensberger C, Wieg L, Willruth A, Steinhard J, Gembruch U, Doelle A, Bahlmann F, Kawecki A, Degenhardt J, Wolter A, Herrmann J, Axt-Fliedner R (2016) Fetal Cardiac Imaging Research Group Germany. Evaluation of right ventricular function in fetal hypoplastic left heart syndrome by color tissue Doppler imaging. Ultrasound Obstet Gynecol 47(6):732\u2013738. https:\/\/doi.org\/10.1002\/uog.14940","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"6857_CR10","doi-asserted-by":"publisher","first-page":"E26","DOI":"10.1055\/s-0042-124501","volume":"3","author":"C Enzensberger","year":"2017","unstructured":"Enzensberger C, Achterberg F, Degenhardt J, Wolter A, Graupner O, Herrmann J, Axt-Fliedner R (2017) Feasibility and reproducibility of two-dimensional wall motion tracking (WMT) in fetal echocardiography. Ultrasound Int Open 3(1):E26\u2013E33. https:\/\/doi.org\/10.1055\/s-0042-124501","journal-title":"Ultrasound Int Open"},{"issue":"1","key":"6857_CR11","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.echo.2011.09.016","volume":"25","author":"T Ishii","year":"2012","unstructured":"Ishii T, McElhinney DB, Harrild DM, Marcus EN, Sahn DJ, Truong U, Tworetzky W (2012) Circumferential and longitudinal ventricular strain in the normal human fetus. J Am Soc Echocardiogr 25(1):105\u2013111. https:\/\/doi.org\/10.1016\/j.echo.2011.09.016","journal-title":"J Am Soc Echocardiogr"},{"issue":"12","key":"6857_CR12","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1016\/j.echo.2012.09.011","volume":"25","author":"L Kapusta","year":"2012","unstructured":"Kapusta L, Mainzer G, Weiner Z, Deutsch L, Khoury A, Haddad S, Lorber A (2012) Second trimester ultrasound: reference values for two-dimensional speckle tracking-derived longitudinal strain, strain rate and time to peak deformation of the fetal heart. J Am Soc Echocardiogr 25(12):1333\u20131341. https:\/\/doi.org\/10.1016\/j.echo.2012.09.011","journal-title":"J Am Soc Echocardiogr"},{"issue":"9","key":"6857_CR13","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1016\/j.echo.2020.03.013","volume":"33","author":"J Semmler","year":"2020","unstructured":"Semmler J, Day TG, Georgiopoulos G, Garcia-Gonzalez C, Aguilera J, Vigneswaran TV, Zidere V, Miller OI, Sharland G, Charakida M, Simpson JM (2020) Fetal speckle-tracking: impact of angle of insonation and frame rate on global longitudinal strain. J Am Soc Echocardiogr 33(9):1141-1146.e2. https:\/\/doi.org\/10.1016\/j.echo.2020.03.013","journal-title":"J Am Soc Echocardiogr"},{"issue":"6","key":"6857_CR14","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1002\/uog.14736","volume":"45","author":"R Axt-Fliedner","year":"2015","unstructured":"Axt-Fliedner R, Graupner O, Kawecki A, Degenhardt J, Herrmann J, Tenzer A, Doelle A, Willruth A, Steinhard J, Gembruch U, Bahlmann F, Enzensberger C (2015) Fetal Cardiac Imaging Research Group, Germany. Evaluation of right ventricular function in fetuses with hypoplastic left heart syndrome using tissue Doppler techniques. Ultrasound Obstet Gynecol 45(6):670\u2013677. https:\/\/doi.org\/10.1002\/uog.14736","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"10","key":"6857_CR15","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1016\/j.echo.2012.06.005","volume":"25","author":"PA Brooks","year":"2012","unstructured":"Brooks PA, Khoo NS, Mackie AS, Hornberger LK (2012) Right ventricular function in fetal hypoplastic left heart syndrome. J Am Soc Echocardiogr 25(10):1068\u20131074. https:\/\/doi.org\/10.1016\/j.echo.2012.06.005","journal-title":"J Am Soc Echocardiogr"},{"issue":"5","key":"6857_CR16","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.echo.2013.02.001","volume":"26","author":"S Natarajan","year":"2013","unstructured":"Natarajan S, Szwast A, Tian Z, McCann M, Soffer D, Rychik J (2013) Right ventricular mechanics in the fetus with hypoplastic left heart syndrome. J Am Soc Echocardiogr 26(5):515\u2013520. https:\/\/doi.org\/10.1016\/j.echo.2013.02.001","journal-title":"J Am Soc Echocardiogr"},{"issue":"4","key":"6857_CR17","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1016\/j.athoracsur.2008.11.032","volume":"87","author":"A Szwast","year":"2009","unstructured":"Szwast A, Tian Z, McCann M, Donaghue D, Rychik J (2009) Right ventricular performance in the fetus with hypoplastic left heart syndrome. Ann Thorac Surg 87(4):1214\u20131219. https:\/\/doi.org\/10.1016\/j.athoracsur.2008.11.032","journal-title":"Ann Thorac Surg"},{"issue":"9","key":"6857_CR18","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1016\/s0002-9149(00)01131-0","volume":"86","author":"K Altmann","year":"2000","unstructured":"Altmann K, Printz BF, Solowiejczky DE, Gersony WM, Quaegebeur J, Apfel HD (2000) Two-dimensional echocardiographic assessment of right ventricular function as a predictor of outcome in hypoplastic left heart syndrome. Am J Cardiol 86(9):964\u2013968. https:\/\/doi.org\/10.1016\/s0002-9149(00)01131-0","journal-title":"Am J Cardiol"},{"issue":"1","key":"6857_CR19","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1002\/uog.2824","volume":"28","author":"R Axt-Fliedner","year":"2006","unstructured":"Axt-Fliedner R, Kreiselmaier P, Schwarze A, Krapp M, Gembruch U (2006) Development of hypoplastic left heart syndrome after diagnosis of aortic stenosis in the first trimester by early echocardiography. Ultrasound Obstet Gynecol 28(1):106\u2013109. https:\/\/doi.org\/10.1002\/uog.2824","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"7","key":"6857_CR20","doi-asserted-by":"publisher","first-page":"E38","DOI":"10.1055\/s-0032-1325376","volume":"33","author":"C Enzensberger","year":"2012","unstructured":"Enzensberger C, Vogel M, Degenhardt J, Fass N, Kawecki A, Kohl T, Widriani E, Axt-Fliedner R (2012) Fetal pulmonary venous flow and restrictive foramen ovale in hypoplastic left heart. Ultraschall Med 33(7):E38\u2013E45. https:\/\/doi.org\/10.1055\/s-0032-1325376","journal-title":"Ultraschall Med"},{"issue":"2","key":"6857_CR21","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s00246-014-1015-2","volume":"36","author":"D Schranz","year":"2015","unstructured":"Schranz D, Bauer A, Reich B, Steinbrenner B, Recla S, Schmidt D, Apitz C, Thul J, Valeske K, Bauer J, M\u00fcller M, Jux C, Michel-Behnke I, Akint\u00fcrk H (2015) Fifteen-year single center experience with the \u201cGiessen Hybrid\u201d approach for hypoplastic left heart and variants: current strategies and outcomes. Pediatr Cardiol 36(2):365\u2013373. https:\/\/doi.org\/10.1007\/s00246-014-1015-2","journal-title":"Pediatr Cardiol"},{"issue":"4","key":"6857_CR22","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1016\/j.jtcvs.2014.09.028","volume":"149","author":"C Yerebakan","year":"2015","unstructured":"Yerebakan C, Murray J, Valeske K, Thul J, Elmontaser H, Mueller M, Mann V, Ostermayer S, Latus H, Apitz C, Schranz D, Akintuerk H (2015) Long-term results of biventricular repair after initial Giessen hybrid approach for hypoplastic left heart variants. J Thorac Cardiovasc Surg 149(4):1112\u20131120. https:\/\/doi.org\/10.1016\/j.jtcvs.2014.09.028. (Discussion 1120\u20132.e2)","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"4","key":"6857_CR23","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1542\/peds.18.4.513","volume":"18","author":"DH Andersen","year":"1956","unstructured":"Andersen DH, Kelly J (1956) Endocardial fibro-elastosis. I. Endocardial fibro-elastosis associated with congenital malformations of the heart. Pediatrics 18(4):513\u2013538","journal-title":"Pediatrics"},{"issue":"6","key":"6857_CR24","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1136\/hrt.66.6.419","volume":"66","author":"GK Sharland","year":"1991","unstructured":"Sharland GK, Chita SK, Fagg NL, Anderson RH, Tynan M, Cook AC, Allan LD (1991) Left ventricular dysfunction in the fetus: relation to aortic valve anomalies and endocardial fibroelastosis. Br Heart J 66(6):419\u2013424. https:\/\/doi.org\/10.1136\/hrt.66.6.419","journal-title":"Br Heart J"},{"issue":"5","key":"6857_CR25","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1136\/hrt.51.5.492","volume":"51","author":"PC Ursell","year":"1984","unstructured":"Ursell PC, Neill CA, Anderson RH, Ho SY, Becker AE, Gerlis LM (1984) Endocardial fibroelastosis and hypoplasia of the left ventricle in neonates without significant aortic stenosis. Br Heart J 51(5):492\u2013497. https:\/\/doi.org\/10.1136\/hrt.51.5.492","journal-title":"Br Heart J"},{"key":"6857_CR26","unstructured":"http:\/\/fetal.parameterz.com\/app#ventricles"},{"issue":"9","key":"6857_CR27","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1159\/000508881","volume":"47","author":"M Meister","year":"2020","unstructured":"Meister M, Axt-Fliedner R, Graupner O, Kuhn V, Wolter A, G\u00f6tte M, Enzensberger C (2020) Atrial and ventricular deformation analysis in normal fetal hearts using two-dimensional speckle tracking echocardiography. Fetal Diagn Ther 47(9):699\u2013710. https:\/\/doi.org\/10.1159\/000508881","journal-title":"Fetal Diagn Ther"},{"issue":"3","key":"6857_CR28","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1515\/jpm-2021-0162","volume":"50","author":"O Graupner","year":"2021","unstructured":"Graupner O, Ried C, Wildner NK, Ortiz JU, Kuschel B, Haller B, Oberhoffer R, Wacker-Gu\u00dfmann A, Lobmaier SM (2021) Myocardial deformation analysis in late-onset small-for-gestational-age and growth-restricted fetuses using two-dimensional speckle tracking echocardiography: a prospective cohort study. J Perinat Med 50(3):305\u2013312. https:\/\/doi.org\/10.1515\/jpm-2021-0162","journal-title":"J Perinat Med"},{"issue":"1","key":"6857_CR29","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1038\/s41598-020-57694-4","volume":"10","author":"FY Wong","year":"2020","unstructured":"Wong FY, Veldman A, Sasi A, Teoh M, Edwards A, Chan Y, Graupner O, Enzensberger C, Axt-Fliedner R, Black MJ, Schranz D (2020) Induction of left ventricular hypoplasia by occluding the foramen ovale in the fetal lamb. Sci Rep 10(1):880. https:\/\/doi.org\/10.1038\/s41598-020-57694-4","journal-title":"Sci Rep"},{"issue":"4","key":"6857_CR30","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1002\/uog.7674","volume":"36","author":"J Rychik","year":"2010","unstructured":"Rychik J, Szwast A, Natarajan S, Quartermain M, Donaghue DD, Combs J, Gaynor JW, Gruber PJ, Spray TL, Bebbington M, Johnson MP (2010) Perinatal and early surgical outcome for the fetus with hypoplastic left heart syndrome: a 5-year single institutional experience. Ultrasound Obstet Gynecol 36(4):465\u2013470. https:\/\/doi.org\/10.1002\/uog.7674","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"6857_CR31","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1161\/CIRCULATIONAHA.107.738559","volume":"117","author":"P Khairy","year":"2008","unstructured":"Khairy P, Fernandes SM, Mayer JE Jr, Triedman JK, Walsh EP, Lock JE, Landzberg MJ (2008) Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery. Circulation 117(1):85\u201392. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.107.738559","journal-title":"Circulation"},{"issue":"7","key":"6857_CR32","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s00246-018-1912-x","volume":"39","author":"SJ Zaidi","year":"2018","unstructured":"Zaidi SJ, Penk J, Cui VW, Kanjanauthai S, Roberson DA (2018) Right ventricular systolic function parameters in hypoplastic left heart Syndrome. Pediatr Cardiol 39(7):1423\u20131432. https:\/\/doi.org\/10.1007\/s00246-018-1912-x","journal-title":"Pediatr Cardiol"},{"issue":"10","key":"6857_CR33","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1002\/pd.3939","volume":"32","author":"TA Miller","year":"2012","unstructured":"Miller TA, Puchalski MD, Weng C, Menon SC (2012) Regional and global myocardial deformation of the fetal right ventricle in hypoplastic left heart syndrome. Prenat Diagn 32(10):949\u2013953. https:\/\/doi.org\/10.1002\/pd.3939","journal-title":"Prenat Diagn"},{"issue":"8","key":"6857_CR34","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1017\/S1047951115002267","volume":"25","author":"M Kaplinski","year":"2015","unstructured":"Kaplinski M, Cohen MS (2015) Characterising adequacy or inadequacy of the borderline left ventricle: what tools can we use? Cardiol Young 25(8):1482\u20131488. https:\/\/doi.org\/10.1017\/S1047951115002267","journal-title":"Cardiol Young"},{"issue":"19","key":"6857_CR35","doi-asserted-by":"publisher","first-page":"e016422","DOI":"10.1161\/JAHA.120.016422","volume":"9","author":"S Nishitani","year":"2020","unstructured":"Nishitani S, Torii N, Imai H, Haraguchi R, Yamada S, Takakuwa T (2020) Development of helical myofiber tracts in the human fetal heart: analysis of myocardial fiber formation in the left ventricle from the late human embryonic period using diffusion tensor magnetic resonance imaging. J Am Heart Assoc 9(19):e016422. https:\/\/doi.org\/10.1161\/JAHA.120.016422","journal-title":"J Am Heart Assoc"},{"issue":"15","key":"6857_CR36","doi-asserted-by":"publisher","first-page":"4456","DOI":"10.3390\/jcm11154456","volume":"11","author":"J Ma","year":"2022","unstructured":"Ma J, Yuan Y, Zhang L, Chen S, Cao H, Hong L, Liu J, Song X, Shi J, Zhang Y, Cui L, Zhou X, Xie M (2022) Evaluation of right ventricular function and myocardial microstructure in fetal hypoplastic left heart syndrome. J Clin Med 11(15):4456. https:\/\/doi.org\/10.3390\/jcm11154456","journal-title":"J Clin Med"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-022-06857-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-022-06857-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-022-06857-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T09:12:21Z","timestamp":1677834741000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-022-06857-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,10]]},"references-count":36,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["6857"],"URL":"https:\/\/doi.org\/10.1007\/s00404-022-06857-x","relation":{},"ISSN":["1432-0711"],"issn-type":[{"type":"electronic","value":"1432-0711"}],"subject":[],"published":{"date-parts":[[2023,2,10]]},"assertion":[{"value":"12 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national guidelines on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008, and has been approved by the institutional committee (Justus Liebig University Giessen, Protocol No. 209\/11).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}