{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T15:19:38Z","timestamp":1776179978388,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"DOI":"10.1007\/s00404-023-07071-z","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T12:04:56Z","timestamp":1684152296000},"page":"579-586","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of fixed and flexible progestin-primed ovarian stimulation protocols to prevent premature luteinization in patients with diminished ovarian reserve"],"prefix":"10.1007","volume":"308","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5064-5267","authenticated-orcid":false,"given":"G\u00fcl\u015fen","family":"Do\u011fan Durda\u011f","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0052-8000","authenticated-orcid":false,"given":"P\u0131nar","family":"\u00c7a\u011flar Ayta\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8309-3537","authenticated-orcid":false,"given":"Didem","family":"Alka\u015f Ya\u011f\u0131n\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2165-9168","authenticated-orcid":false,"given":"Sel\u00e7uk","family":"Yetkinel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1244-7419","authenticated-orcid":false,"given":"Tayfun","family":"\u00c7ok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1505-5288","authenticated-orcid":false,"given":"Erhan","family":"\u015eim\u015fek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,5,13]]},"reference":[{"issue":"1","key":"7071_CR1","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1093\/humupd\/dmaa040","volume":"27","author":"B Ata","year":"2021","unstructured":"Ata B, Capuzzo M, Turkgeldi E, Yildiz S, La Marca A (2021) Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses. Hum Reprod Update 27(1):48\u201366. https:\/\/doi.org\/10.1093\/humupd\/dmaa040","journal-title":"Hum Reprod Update"},{"issue":"1","key":"7071_CR2","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.fertnstert\/2015.03.022","volume":"104","author":"Y Kuang","year":"2015","unstructured":"Kuang Y, Chen Q, Fu Y, Wang Y, Hong Q, Lyu Q et al (2015) Medroxyprogesterone acetate is an effective oral alternative for preventing premature luteinizing hormone surges in women undergoing controlled ovarian hyperstimulation for in vitro fertilization. Fertil Steril 104(1):62-70.e3. https:\/\/doi.org\/10.1016\/j.fertnstert\/2015.03.022","journal-title":"Fertil Steril"},{"issue":"3","key":"7071_CR3","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1007\/s-00404-018-4856-8","volume":"298","author":"N Iwami","year":"2018","unstructured":"Iwami N, Kawamata M, Ozawa N, Yamamoto T, Watanabe E, Moriwaka O et al (2018) New trial of progestin-primed ovarian stimulation using dydrogesterone versus a typical GnRH antagonist regimen in assisted reproductive technology. Arch Gynecol Obstet 298(3):663\u2013671. https:\/\/doi.org\/10.1007\/s-00404-018-4856-8","journal-title":"Arch Gynecol Obstet"},{"issue":"4","key":"7071_CR4","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.fertnstert\/2019.06.009","volume":"112","author":"S Yildiz","year":"2019","unstructured":"Yildiz S, Turkgeldi E, Angun B, Eraslan A, Urman B, Ata B (2019) Comparison of a novel flexible progestin primed ovarian stimulation protocol and the flexible gonadotropin-releasing hormone antagonist protocol for assisted reproductive technology. Fertil Steril 112(4):677\u2013683. https:\/\/doi.org\/10.1016\/j.fertnstert\/2019.06.009","journal-title":"Fertil Steril"},{"key":"7071_CR5","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1080\/14647273.2020.1794060","volume":"25","author":"E Turkgeldi","year":"2022","unstructured":"Turkgeldi E, Yildiz S, Cekic SG, Shakerian B, Keles I, Ata B (2022) Effectiveness of the flexible progestin primed ovarian stimulation protocol compared to the flexible GnRH antagonist protocol in women with decreased ovarian reserve. Hum Fertil (Camb) 25:306\u2013312. https:\/\/doi.org\/10.1080\/14647273.2020.1794060","journal-title":"Hum Fertil (Camb)"},{"issue":"12","key":"7071_CR6","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1007\/s10815-015-0595-y","volume":"32","author":"J Cohen","year":"2015","unstructured":"Cohen J, Chabbert-Buffet N, Darai E (2015) Diminished ovarian reserve, premature ovarian failure, poor ovarian responder\u2014a plea for universal definitions. J Assist Reprod Genet 32(12):1709\u20131712. https:\/\/doi.org\/10.1007\/s10815-015-0595-y","journal-title":"J Assist Reprod Genet"},{"issue":"6","key":"7071_CR7","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1016\/j.fertnstert.2003.07.002","volume":"80","author":"E Bosch","year":"2003","unstructured":"Bosch E, Valencia I, Escudero E, Crespo J, Sim\u00f3n C, Remoh\u00ed J et al (2003) Premature luteinization during gonadotropin-releasing hormone antagonist cycles and its relationship with in vitro fertilization outcome. Fertil Steril 80(6):1444\u20131449. https:\/\/doi.org\/10.1016\/j.fertnstert.2003.07.002","journal-title":"Fertil Steril"},{"key":"7071_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.688237","author":"S Mumusoglu","year":"2021","unstructured":"Mumusoglu S, Polat M, Ozbek IY, Bozdag G, Papanikolaou EG, Esteves SC et al (2021) Preparation of the endometrium for frozen embryo transfer: a systematic review. Front Endocrinol. https:\/\/doi.org\/10.3389\/fendo.2021.688237","journal-title":"Front Endocrinol"},{"issue":"2","key":"7071_CR9","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1093\/humupd\/dmw047","volume":"23","author":"N Massin","year":"2017","unstructured":"Massin N (2017) New stimulation regimens: endogenous and exogenous progesterone use to block the LH surge during ovarian stimulation for IVF. Hum Reprod Update 23(2):211\u2013220. https:\/\/doi.org\/10.1093\/humupd\/dmw047","journal-title":"Hum Reprod Update"},{"issue":"2","key":"7071_CR10","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1093\/humrep\/dex367","volume":"33","author":"S Yu","year":"2018","unstructured":"Yu S, Long H, Chang HY-N, Liu Y, Gao H, Zhu J et al (2018) New application of dydrogesterone as a part of a progestin-primed ovarian stimulation protocol for IVF: a randomized controlled trial including 516 first IVF\/ICSI cycles. Hum Reprod 33(2):229\u2013237. https:\/\/doi.org\/10.1093\/humrep\/dex367","journal-title":"Hum Reprod"},{"issue":"1","key":"7071_CR11","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.fertnstert.2014.04.010","volume":"102","author":"DE Reichman","year":"2014","unstructured":"Reichman DE, Zakarin L, Chao K, Meyer L, Davis OK, Rosenwaks Z (2014) Diminished ovarian reserve is the predominant risk factor for gonadotropin-releasing hormone antagonist failure resulting in breakthrough luteinizing hormone surges in in vitro fertilization cycles. Fertil Steril 102(1):99\u2013102. https:\/\/doi.org\/10.1016\/j.fertnstert.2014.04.010","journal-title":"Fertil Steril"},{"issue":"3","key":"7071_CR12","doi-asserted-by":"publisher","first-page":"191","DOI":"10.4103\/jhrs.JHRS_133_19","volume":"13","author":"PK Kochhar","year":"2020","unstructured":"Kochhar PK, Ghosh P (2020) Diminished ovarian reserve predisposes to premature luteinizing hormone surges in gonadotropin-releasing hormone antagonist cycles in in vitro fertilization. J Hum Reprod Sci 13(3):191. https:\/\/doi.org\/10.4103\/jhrs.JHRS_133_19","journal-title":"J Hum Reprod Sci"},{"issue":"12","key":"7071_CR13","doi-asserted-by":"publisher","first-page":"5746","DOI":"10.1210\/jc.2002-020622","volume":"87","author":"NA Klein","year":"2002","unstructured":"Klein NA, Harper AJ, Houmard BS, Sluss PM, Soules MR (2002) Is the short follicular phase in older women secondary to advanced or accelerated dominant follicle development? J Clin Endocrinol Metab 87(12):5746\u20135750. https:\/\/doi.org\/10.1210\/jc.2002-020622","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"7071_CR14","doi-asserted-by":"publisher","first-page":"293","DOI":"10.4274\/jtgga.galenos.2020.2020.0110","volume":"22","author":"GD Durda\u011f","year":"2021","unstructured":"Durda\u011f GD, Bekta\u015f G, T\u00fcrky\u0131lmaz E, G\u00f6ktepe H, S\u00f6nmezer M, \u015e\u00fck\u00fcr YE et al (2021) The efficacy of dydrogesterone use to suppress premature luteinizing hormone surge on cycle outcomes in controlled ovarian stimulation. J Turk Ger Gynecol Assoc 22(4):293. https:\/\/doi.org\/10.4274\/jtgga.galenos.2020.2020.0110","journal-title":"J Turk Ger Gynecol Assoc"},{"key":"7071_CR15","doi-asserted-by":"publisher","first-page":"796","DOI":"10.3389\/fendo.2019.00796","volume":"10","author":"Q Chen","year":"2019","unstructured":"Chen Q, Chai W, Wang Y, Cai R, Zhang S, Lu X et al (2019) Progestin vs gonadotropin-releasing hormone antagonist for the prevention of premature luteinizing hormone surges in poor responders undergoing in vitro fertilization treatment: a randomized controlled trial. Front Endocrinol (Lausanne) 10:796. https:\/\/doi.org\/10.3389\/fendo.2019.00796","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"7071_CR16","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.jogoh.2018.10.008","volume":"48","author":"P Huang","year":"2019","unstructured":"Huang P, Tang M, Qin A (2019) Progestin-primed ovarian stimulation is a feasible method for poor ovarian responders undergoing in IVF\/ICSI compared to a GnRH antagonist protocol: a retrospective study. J Gynecol Obstet Hum Reprod 48(2):99\u2013102. https:\/\/doi.org\/10.1016\/j.jogoh.2018.10.008","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"1","key":"7071_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12958-019-0518-3","volume":"17","author":"Q Peng","year":"2019","unstructured":"Peng Q, Cao X, Wang J, Wang L, Xu J, Ji X et al (2019) Progestin-primed ovarian stimulation vs mild stimulation in women with advanced age above 40: a retrospective cohort study. Reprod Biol Endocrinol 17(1):1\u20137. https:\/\/doi.org\/10.1186\/s12958-019-0518-3","journal-title":"Reprod Biol Endocrinol"},{"key":"7071_CR18","doi-asserted-by":"publisher","first-page":"705264","DOI":"10.3389\/fendo.2021.705264","volume":"12","author":"M Du","year":"2021","unstructured":"Du M, Zhang J, Li Z, Liu X, Li J, Liu W et al (2021) Comparison of the cumulative live birth rates of progestin-primed ovarian stimulation and flexible GnRH antagonist protocols in patients with low prognosis. Front Endocrinol (Lausanne) 12:705264. https:\/\/doi.org\/10.3389\/fendo.2021.705264","journal-title":"Front Endocrinol (Lausanne)"},{"key":"7071_CR19","doi-asserted-by":"publisher","first-page":"797227","DOI":"10.3389\/fendo.2021.797227","volume":"12","author":"E Kalafat","year":"2022","unstructured":"Kalafat E, Dizdar M, Turkgeldi E, Yildiz S, Keles I, Ata B (2022) The comparison of fixed and flexible progestin primed ovarian stimulation on mature oocyte yield in women at risk of premature ovarian insufficiency. Front Endocrinol (Lausanne) 12:797227. https:\/\/doi.org\/10.3389\/fendo.2021.797227","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"7071_CR20","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/j.fertnstert.2010.05.052","volume":"95","author":"EM Kolibianakis","year":"2011","unstructured":"Kolibianakis EM, Venetis CA, Kalogeropoulou L, Papanikolaou E, Tarlatzis BC (2011) Fixed versus flexible gonadotropin-releasing hormone antagonist administration in in vitro fertilization: a randomized controlled trial. Fertil Steril 95(2):558\u2013562. https:\/\/doi.org\/10.1016\/j.fertnstert.2010.05.052","journal-title":"Fertil Steril"},{"issue":"4","key":"7071_CR21","doi-asserted-by":"publisher","first-page":"400","DOI":"10.4103\/jhrs.jhrs_75_21","volume":"14","author":"I Kahyaoglu","year":"2021","unstructured":"Kahyaoglu I, Dogru HY, Kaplanoglu I, Ozgu-Erdinc AS, Dilbaz S, Mollamahmutoglu L (2021) Effect of antagonist start day on cycle outcomes in poor responders. J Hum Reprod Sci 14(4):400\u2013405. https:\/\/doi.org\/10.4103\/jhrs.jhrs_75_21","journal-title":"J Hum Reprod Sci"},{"issue":"4","key":"7071_CR22","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1007\/s00404-009-1248-0","volume":"281","author":"EB Kili\u00e7dag","year":"2010","unstructured":"Kili\u00e7dag EB, Haydardedeoglu B, Cok T, Hacivelioglu SO, Bagis T (2010) Premature progesterone elevation impairs implantation and live birth rates in GnRH-agonist IVF\/ICSI cycles. Arch Gynecol Obstet 281(4):747\u2013752. https:\/\/doi.org\/10.1007\/s00404-009-1248-0","journal-title":"Arch Gynecol Obstet"},{"key":"7071_CR23","doi-asserted-by":"publisher","first-page":"644456","DOI":"10.3389\/fendo.2021.644456","volume":"12","author":"S Zhang","year":"2021","unstructured":"Zhang S, Yin Y, Li Q, Zhang C (2021) Comparison of cumulative live birth rates between GnRH-A and PPOS in low-prognosis patients according to POSEIDON criteria: a cohort study. Front Endocrinol (Lausanne) 12:644456. https:\/\/doi.org\/10.3389\/fendo.2021.644456","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-023-07071-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-023-07071-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-023-07071-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T14:11:18Z","timestamp":1687788678000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-023-07071-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,13]]},"references-count":23,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["7071"],"URL":"https:\/\/doi.org\/10.1007\/s00404-023-07071-z","relation":{},"ISSN":["1432-0711"],"issn-type":[{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,13]]},"assertion":[{"value":"11 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by Ba\u015fkent University Institutional Review Board (Project No. KA22\/333).This study was performed in accordance with Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent to participate the study was obtained from all patients prior to their treatment.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent for publication of the data was obtained from all patients prior to their treatment.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}