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Early screening for PPD is essential to ensure appropriate treatment and support. The present study aimed to assess whether maternal prepartum anaemia influences the likelihood of developing PPD within 3\u00a0days after delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In collaboration with the Department of Psychiatry, a prospective observational study was carried out at the Gynaecology and Obstetrics Department of the University of Campania \u201cLuigi Vanvitelli\u201d in Naples. A total of 211 full-term pregnant women were enrolled, and their predelivery haemoglobin value was recorded. Women with gestational diabetes, hypertension, pre-eclampsia, intrauterine growth restriction, intellectual disability, or pre-existing diagnosis of psychotic spectrum disorder were excluded. Participants provided written informed consent to fill out the Edinburgh Postnatal Depression Scale (EPDS) 3\u00a0days after delivery. EPDS cut-off score of\u2009\u2265\u200910 was used to identify women at risk of developing PPD. Statistical analysis was performed using Student's t test, the Wilcoxon Rank Sum test, and linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The participants were categorized into 2 groups based on EPDS scores: EPDS\u2009&lt;\u200910 (176 patients) or EPDS\u2009\u2265\u200910 (35 patients). The two groups showed homogeneity in terms of socio-demographic and clinical characteristics. The mean haemoglobin values of anaemic pregnant women in the EPDS\u2009\u2264\u200910 group (11.78\u2009\u00b1\u20091.39\u00a0g\/dl) and the EPDS\u2009&gt;\u200910 group (11.62\u2009\u00b1\u20091.27\u00a0g\/dl) were not significantly different (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.52). There was no significant correlation between the predelivery haemoglobin value and the EPDS postpartum score of\u2009&lt;\u200910 or\u2009\u2265\u200910. The Wilcoxon Rank Sum test and the estimated coefficients of the linear regression model did not show any statistical relationship between continuous and binary haemoglobin values.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study found that maternal prepartum anaemia did not negatively impact the likelihood of developing postpartum depressive symptoms, in the first 3\u00a0days after delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-023-07344-7","type":"journal-article","created":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T09:02:06Z","timestamp":1707728526000},"page":"1099-1108","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Is there a correlation between prepartum anaemia and an increased likelihood of developing postpartum depression? 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