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All singleton deliveries from June 2020 to January 2022 were included. Univariate analysis was followed by multivariate analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of 26,827 singleton deliveries, 563 women had peripartum COVID-19, associated with preterm deliveries both near-term and remote from term [adjusted odds ratio (aOR) 1.6 and 2.0, respectively, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.007 and 0.003]. Women with peripartum COVID-19 had a significantly higher rate of disseminated intravascular coagulation (DIC) (aOR 23.0, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). Conversely, peripartum COVID-19 peripartum COVID-19 was negatively associated with premature rupture of membranes and prolonged maternal length of stay (aOR 0.7 and 0.5, respectively, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.006 and &lt;0.001).<\/jats:p>\n                <jats:p>In cesarean delivery (CDs), patients with COVID-19 had higher rate of urgent CDs (75.5 vs. 56.1%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), higher rate of regional anesthesia (74.5 vs. 64.9%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.049), and longer anesthesia duration (86.1 vs. 53.4 min, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). CD rate due to non-reassuring fetal heart rate (NRFHR) was significantly higher in women with COVID-19 (29.6 vs. 17.4%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002). Conversely, CDs rate due to history of previous single CD was significantly higher in patients without COVID-19 diagnosis (13.6 vs. 4.1%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.006).<\/jats:p>\n                <jats:p>Concerning neonatal outcomes, an association\u00a0has been observed between COVID-19 and low one-minute APGAR\u00a0score &lt;5,\u00a0as well as neonatal COVID-19 infection (aOR 61.8 and 1.7 respectively, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001 and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.037).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Peripartum COVID-19 is associated with preterm deliveries, urgent CDs and DIC, potentially aligning with the infection\u2019s pathophysiology and coagulation alterations.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00404-024-07536-9","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T13:01:46Z","timestamp":1715000506000},"page":"793-800","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perinatal outcomes among pregnant patients with peripartum coronavirus disease 2019 infection"],"prefix":"10.1007","volume":"310","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8261-5364","authenticated-orcid":false,"given":"Alla","family":"Saban","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noa Leybovitz","family":"Haleluya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yael","family":"Geva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neta","family":"Geva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reli","family":"Hershkovitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"key":"7536_CR1","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.15585\/mmwr.mm6944e3","volume":"69","author":"LD Zambrano","year":"2020","unstructured":"Zambrano LD, Ellington S, Strid P et al (2020) Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status\u2014United States, January 22-October 3, 2020. 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