{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:06:15Z","timestamp":1791576375168,"version":"4.3.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002744","name":"Bar-Ilan University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002744","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>Early diagnosis of retained products of conception (RPOC) is critical for directing clinical management and for preventing associated complications. This study aimed to evaluate the utility of post-delivery ultrasound in patients with risk factors for RPOC.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Study design<\/jats:title>\n            <jats:p>A retrospective cohort-study was conducted in a\u00a0single tertiary university-affiliated hospital (January 2016\u2013September 2022). Sonographic evaluation, including endometrium thickness measurement and color Doppler, were reviewed of women with risk factors for RPOC: postpartum hemorrhage, a hemoglobin drop\u2009&gt;\u20094\u00a0g\/dl, manual removal of the placenta, and suspicious placenta. Results of early postpartum ultrasound (within 48\u00a0h), misoprostol administration and hysteroscopies were evaluated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Of the 591 women included, RPOC was suspected in 141 (24%). Endometrial thickness\u2009&gt;\u20095\u00a0mm was associated with sonographic RPOC diagnosis in 58%. Suspected sonographic RPOC was concluded for 100%, 92% and 7% of the women with marked, moderate, and undetectable vascularity, respectively, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001. Misoprostol 1000\u00a0mcg per rectum (PR) was administered to 86% of those with suspected RPOC; only 11% of them needed an operative hysteroscopy for removal of the RPOC. RPOC on a pathology report was confirmed for 71% of those who underwent hysteroscopy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Postpartum\u00a0transabdominal ultrasonography within 48\u00a0h of delivery\u00a0was effective for assessing RPOC. For appropriate triage, color Doppler\u00a0grading increased the accuracy of RPOC diagnosis. Misoprostol treatment was successful in 88% of women with suspected sonographic RPOC. The combination of sonographic evaluation and misoprostol treatment for suspected RPOC might lower the rate of unnecessary invasive procedures.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00404-024-07688-8","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T05:02:07Z","timestamp":1723438927000},"page":"367-373","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sonographic evaluation of retained products of conception within 48\u00a0h following delivery: a retrospective cohort study"],"prefix":"10.1007","volume":"311","author":[{"given":"Nadine","family":"Ashkar Majadla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0131-3936","authenticated-orcid":false,"given":"Raneen","family":"Abu Shqara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safaa","family":"Haj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inshirah","family":"Sgayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadir","family":"Ghanem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Lowenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwan","family":"Odeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,12]]},"reference":[{"issue":"10","key":"7688_CR1","first-page":"13625","volume":"8","author":"G Antonella","year":"2015","unstructured":"Antonella G, Luisa DB, Chiara A et al (2015) Conservative and timely treatment in retained products of conception: a case report of placenta accreta retention. 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Approval was granted by the Ethics Committee of Galilee medical center (Number 0150\u201322-NHR).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was not obtained to the study design.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}