{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T04:02:38Z","timestamp":1744344158744,"version":"3.40.4"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012305","name":"Universit\u00e0 degli Studi del Molise","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012305","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>To propose an obstetric management model for patients with congenital bladder exstrophy (BE) and multiple previous surgeries, recognizing the unique anatomical variations of each patient and emphasizing the importance of personalized treatment approaches.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We present the obstetric management and delivery of a 32-year-old pregnant woman with congenital BE, focusing on antenatal anatomical assessment, accurate delivery planning and key surgical steps during an elective caesarean section. Additionally, we conduct a comprehensive review of the current literature to enhance understanding of the reproductive implications associated with this exceptionally rare condition.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Following urological magnetic resonance imaging and intraoperative ultrasound, a successful neobladder-saving caesarean section was performed at 37\u00a0weeks, resulting in the delivery of a healthy infant with no maternal complications.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Obstetric management in women with congenital BE presents unique challenges due to its significant impact on urinary and reproductive functions. Careful delivery planning and antenatal anatomical assessment are crucial for optimizing both maternal and fetal outcomes. A personalized, multidisciplinary approach can help minimize potential complications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00404-025-07937-4","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T17:00:27Z","timestamp":1738342827000},"page":"1221-1225","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neobladder saving caesarean section in a pregnant woman with congenital bladder exstrophy"],"prefix":"10.1007","volume":"311","author":[{"given":"Chiara","family":"Granieri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6160-0558","authenticated-orcid":false,"given":"Silvia","family":"D\u2019Ippolito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aniello","family":"Foresta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedetta","family":"Gui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazario","family":"Foschi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Scambia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"issue":"6","key":"7937_CR1","doi-asserted-by":"publisher","first-page":"496.e1","DOI":"10.1016\/j.ajog.2012.03.016","volume":"206","author":"R Deans","year":"2012","unstructured":"Deans R, Banks F, Liao LM, Wood D, Woodhouse C, Creighton SM (2012) Reproductive outcomes in women with classic bladder exstrophy: an observational cross-sectional study. Am J Obstet Gynecol 206(6):496.e1-496.e4966. https:\/\/doi.org\/10.1016\/j.ajog.2012.03.016","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"7937_CR2","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1007\/s11934-013-0332-y","volume":"14","author":"BM Inouye","year":"2013","unstructured":"Inouye BM, Massanyi EZ, Di Carlo H, Shah BB, Gearhart JP (2013) Modern management of bladder exstrophy repair. Curr Urol Rep 14(4):359\u2013365. https:\/\/doi.org\/10.1007\/s11934-013-0332-y","journal-title":"Curr Urol Rep"},{"issue":"3","key":"7937_CR3","doi-asserted-by":"publisher","first-page":"e69","DOI":"10.1016\/j.jpag.2012.02.001","volume":"25","author":"FD Bildircin","year":"2012","unstructured":"Bildircin FD, Ayyildiz HS, Tosun M, Malatyalioglu E, Ariturk E, Sakinci M (2012) Successful pregnancy and delivery in a patient with bladder exstrophy. J Pediatr Adolesc Gynecol 25(3):e69\u2013e71. https:\/\/doi.org\/10.1016\/j.jpag.2012.02.001","journal-title":"J Pediatr Adolesc Gynecol"},{"issue":"2","key":"7937_CR4","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/s0301-2115(00)00318-3","volume":"94","author":"A Mantel","year":"2001","unstructured":"Mantel A, Lemoine JP, Descargues G, Chanavaz I, Mitrofanoff P (2001) Bladder exstrophy: gynecological and obstetrical characteristics with reference to three cases. Eur J Obstet Gynecol Reprod Biol 94(2):296\u2013300. https:\/\/doi.org\/10.1016\/s0301-2115(00)00318-3","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"1","key":"7937_CR5","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1186\/s13256-023-04181-9","volume":"17","author":"S Schrey-Petersen","year":"2023","unstructured":"Schrey-Petersen S, Lacher M, Stepan H (2023) Course of an unplanned and unexpected pregnancy in a 39\u00a0year-old patient with Complex bladder extrophy: a case report. J Med Case Rep 17(1):450. https:\/\/doi.org\/10.1186\/s13256-023-04181-9","journal-title":"J Med Case Rep"},{"issue":"4","key":"7937_CR6","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.jpurol.2010.01.015","volume":"6","author":"MK Farrugia","year":"2010","unstructured":"Farrugia MK, Malone PS (2010) Educational article: The Mitrofanoff procedure. J Pediatr Urol 6(4):330\u2013337. https:\/\/doi.org\/10.1016\/j.jpurol.2010.01.015","journal-title":"J Pediatr Urol"},{"issue":"3","key":"7937_CR7","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1002\/ijgo.12307","volume":"139","author":"M Dap","year":"2017","unstructured":"Dap M, Larmure O, Morel O, Lemelle JL (2017) Pregnancy outcomes among patients with prior bladder exstrophy. Int J Gynaecol Obstet 139(3):368\u2013369. https:\/\/doi.org\/10.1002\/ijgo.12307","journal-title":"Int J Gynaecol Obstet"},{"issue":"4","key":"7937_CR8","doi-asserted-by":"publisher","first-page":"213.e1","DOI":"10.1016\/j.jpurol.2015.04.019","volume":"11","author":"GW Dy","year":"2015","unstructured":"Dy GW, Willihnganz-Lawson KH, Shnorhavorian M et al (2015) Successful pregnancy in patients with exstrophy-epispadias complex: A University of Washington experience. J Pediatr Urol 11(4):213.e1-213.e2136. https:\/\/doi.org\/10.1016\/j.jpurol.2015.04.019","journal-title":"J Pediatr Urol"},{"issue":"4","key":"7937_CR9","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1111\/j.1447-0756.2012.02053.x","volume":"39","author":"A Mandal","year":"2013","unstructured":"Mandal A, Chaudhuri S, Manna SS, Jana SK, Biswas T, Das S (2013) Successful pregnancy outcome in a woman with untreated ectopia vesicae: a case report and review of literature. J Obstet Gynaecol Res 39(4):868\u2013871. https:\/\/doi.org\/10.1111\/j.1447-0756.2012.02053.x","journal-title":"J Obstet Gynaecol Res"},{"issue":"14","key":"7937_CR10","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1055\/s-0041-1739289","volume":"40","author":"DE Werter","year":"2023","unstructured":"Werter DE, Schneeberger C, Mol BWJ et al (2023) The risk of preterm birth in low risk pregnant women with urinary tract infections. Am J Perinatol 40(14):1558\u20131566. https:\/\/doi.org\/10.1055\/s-0041-1739289","journal-title":"Am J Perinatol"},{"issue":"4","key":"7937_CR11","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1007\/s00404-011-1945-3","volume":"284","author":"AK Ebert","year":"2011","unstructured":"Ebert AK, Falkert A, Hofst\u00e4dter A, Reutter H, R\u00f6sch WH (2011) Pregnancy management in women within the bladder-exstrophy-epispadias complex (BEEC) after continent urinary diversion. Arch Gynecol Obstet 284(4):1043\u20131046. https:\/\/doi.org\/10.1007\/s00404-011-1945-3","journal-title":"Arch Gynecol Obstet"},{"issue":"4","key":"7937_CR12","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1007\/s00404-013-2790-3","volume":"288","author":"T Hanprasertpong","year":"2013","unstructured":"Hanprasertpong T, Wootipoom V, Tanthanuch M, Hanprasertpong J (2013) Successful pregnancy in a non-reconstructed congenital bladder extrosphy woman: the first case report. Arch Gynecol Obstet 288(4):955\u2013957. https:\/\/doi.org\/10.1007\/s00404-013-2790-3","journal-title":"Arch Gynecol Obstet"},{"issue":"1","key":"7937_CR13","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1186\/s12884-024-06316-2","volume":"24","author":"A Hosiani","year":"2024","unstructured":"Hosiani A, Smet ME, Nayyar R (2024) A road map for the management of a pregnancy complicated by maternal bladder exstrophy. BMC Pregnancy Childbirth 24(1):195. https:\/\/doi.org\/10.1186\/s12884-024-06316-2","journal-title":"BMC Pregnancy Childbirth"},{"issue":"1","key":"7937_CR14","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1186\/s12884-020-02931-x","volume":"20","author":"S Liu","year":"2020","unstructured":"Liu S, Qu X, Song L, Li N, Xu A (2020) Repeated successful vaginal delivery in a pregnant woman with unrepaired ectopia vesicae and split pelvis: a case study. BMC Pregnancy Childbirth 20(1):290. https:\/\/doi.org\/10.1186\/s12884-020-02931-x","journal-title":"BMC Pregnancy Childbirth"},{"issue":"1","key":"7937_CR15","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.juro.2015.12.099","volume":"196","author":"P Rubenwolf","year":"2016","unstructured":"Rubenwolf P, Thomas C, Th\u00fcroff JW, Stein R (2016) Sexual function and fertility of women with classic bladder exstrophy and continent urinary diversion. J Urol 196(1):140\u2013145. https:\/\/doi.org\/10.1016\/j.juro.2015.12.099","journal-title":"J Urol"},{"issue":"2","key":"7937_CR16","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1479-828x.1998.tb03010.x","volume":"38","author":"D Sharma","year":"1998","unstructured":"Sharma D, Singhal SR, Singhal SK (1998) Successful pregnancy in a patient with previous bladder exstrophy. Aust N Z J Obstet Gynaecol 38(2):227\u2013228. https:\/\/doi.org\/10.1111\/j.1479-828x.1998.tb03010.x","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"6","key":"7937_CR17","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1080\/01443615.2017.1394282","volume":"38","author":"S Bonner","year":"2018","unstructured":"Bonner S, Mohammed Y (2018) Complex maternal congenital anomalies - a rare presentation and delivery through a supra-umbilical abdominal incision. J Obstet Gynaecol 38(6):874\u2013875. https:\/\/doi.org\/10.1080\/01443615.2017.1394282","journal-title":"J Obstet Gynaecol"},{"issue":"3","key":"7937_CR18","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s11934-018-0767-2","volume":"19","author":"MR Kaufman","year":"2018","unstructured":"Kaufman MR (2018) Pelvic organ prolapse and pregnancy in the female bladder exstrophy patient. Curr Urol Rep 19(3):18. https:\/\/doi.org\/10.1007\/s11934-018-0767-2","journal-title":"Curr Urol Rep"},{"issue":"9","key":"7937_CR19","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1007\/s00192-012-1717-z","volume":"23","author":"RS Nakhal","year":"2012","unstructured":"Nakhal RS, Deans R, Creighton SM, Wood D, Woodhouse CR (2012) Genital prolapse in adult women with classical bladder exstrophy. Int Urogynecol J 23(9):1201\u20131205. https:\/\/doi.org\/10.1007\/s00192-012-1717-z","journal-title":"Int Urogynecol J"},{"issue":"5","key":"7937_CR20","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1590\/s1677-55382011000500006","volume":"37","author":"AM Giron","year":"2011","unstructured":"Giron AM, Passerotti CC, Nguyen H, Cruz JA, Srougi M (2011) Bladder exstrophy: reconstructed female patients achieving normal pregnancy and delivering normal babies. Int Braz J Urol 37(5):605\u2013610. https:\/\/doi.org\/10.1590\/s1677-55382011000500006","journal-title":"Int Braz J Urol"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-025-07937-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-025-07937-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-025-07937-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T06:08:11Z","timestamp":1744265291000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-025-07937-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,31]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["7937"],"URL":"https:\/\/doi.org\/10.1007\/s00404-025-07937-4","relation":{},"ISSN":["1432-0711"],"issn-type":[{"type":"electronic","value":"1432-0711"}],"subject":[],"published":{"date-parts":[[2025,1,31]]},"assertion":[{"value":"13 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No relevant conflict of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The patient gave written consent for publication of this study in the journal website, scientific literature websites (such as Pubmed, Sciencedirect, Scoput, etc.) and other applicable sites.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}