{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:45:23Z","timestamp":1777488323977,"version":"3.51.4"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Xiamen Medical Advantage subspecialty construction project","award":["2018296"],"award-info":[{"award-number":["2018296"]}]},{"name":"Xiamen Medical Advantage subspecialty construction project","award":["2018296"],"award-info":[{"award-number":["2018296"]}]},{"DOI":"10.13039\/100007452","name":"Wu Jieping Medical Foundation","doi-asserted-by":"publisher","award":["320.6750.2024-6-14"],"award-info":[{"award-number":["320.6750.2024-6-14"]}],"id":[{"id":"10.13039\/100007452","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22176159"],"award-info":[{"award-number":["22176159"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"DOI":"10.1007\/s00404-025-08033-3","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T22:32:25Z","timestamp":1745965945000},"page":"495-503","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intracytoplasmic sperm injection hampers fertilization rate and pregnancy per initiated cycle in patients with extremely poor ovarian response"],"prefix":"10.1007","volume":"312","author":[{"given":"Jinghua","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanlan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenfang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luxiang","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaijie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianzhi","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiali","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"8033_CR1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/0140-6736(92)92425-F","volume":"340","author":"G Palermo","year":"1992","unstructured":"Palermo G, Joris H, Devroey P, Van Steirteghem AC (1992) Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 340:17\u201318","journal-title":"Lancet"},{"key":"8033_CR2","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1016\/j.fertnstert.2024.07.009","volume":"122","author":"MS Kupka","year":"2024","unstructured":"Kupka MS, Chambers GM, Dyer S, Zegers-Hochschild F, de Mouzon J, Ishihara O et al (2024) International committee for monitoring assisted reproductive technology world report: assisted reproductive technology, 2015 and 2016. Fertil Steril 122:875\u2013893","journal-title":"Fertil Steril"},{"key":"8033_CR3","first-page":"124","volume":"3","author":"A Jewett","year":"2022","unstructured":"Jewett A, Warner L, Kawwass JF, Mehta A, Eisenberg ML, Nangia AK et al (2022) Assisted reproductive technology cycles involving male factor infertility in the United States, 2017\u20132018: data from the national assisted reproductive technology surveillance system. F S Rep 3:124\u2013130","journal-title":"F S Rep"},{"key":"8033_CR4","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1007\/s10815-011-9614-9","volume":"28","author":"M Luna","year":"2011","unstructured":"Luna M, Bigelow C, Duke M, Ruman J, Sandler B, Grunfeld L et al (2011) Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved? J Assist Reprod Genet 28:911\u2013915","journal-title":"J Assist Reprod Genet"},{"key":"8033_CR5","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.fertnstert.2006.07.1515","volume":"87","author":"I Gozlan","year":"2007","unstructured":"Gozlan I, Dor A, Farber B, Meirow D, Feinstein S, Levron J (2007) Comparing intracytoplasmic sperm injection and in vitro fertilization in patients with single oocyte retrieval. Fertil Steril 87:515\u2013518","journal-title":"Fertil Steril"},{"key":"8033_CR6","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1093\/humrep\/dead197","volume":"38","author":"J Smeenk","year":"2023","unstructured":"Smeenk J, Wyns C, De Geyter C, Kupka M, Bergh C et al (2023) European IVF Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE), ART in Europe 2019: results generated from European registries by ESHRE\u2020. Hum Reprod 38:2321\u201338","journal-title":"Hum Reprod"},{"key":"8033_CR7","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1016\/S0140-6736(21)00535-3","volume":"397","author":"VQ Dang","year":"2021","unstructured":"Dang VQ, Vuong LN, Luu TM, Pham TD, Ho TM, Ha AN et al (2021) Intracytoplasmic sperm injection versus conventional in-vitro fertilisation in couples with infertility in whom the male partner has normal total sperm count and motility: an open-label, randomised controlled trial. Lancet 397:1554\u20131563","journal-title":"Lancet"},{"key":"8033_CR8","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1093\/humrep\/dey118","volume":"33","author":"Z Li","year":"2018","unstructured":"Li Z, Wang AY, Bowman M, Hammarberg K, Farquhar C, Johnson L et al (2018) ICSI does not increase the cumulative live birth rate in non-male factor infertility. Hum Reprod 33:1322\u20131330","journal-title":"Hum Reprod"},{"key":"8033_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2020.101706","volume":"49","author":"AM Abbas","year":"2020","unstructured":"Abbas AM, Hussein RS, Elsenity MA, Samaha II, El Etriby KA, Abd El-Ghany MF et al (2020) Higher clinical pregnancy rate with in-vitro fertilization versus intracytoplasmic sperm injection in treatment of non-male factor infertility: systematic review and meta-analysis. J Gynecol Obstet Hum Reprod 49:101706","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"8033_CR10","doi-asserted-by":"publisher","first-page":"1133512","DOI":"10.3389\/fcell.2023.1133512","volume":"11","author":"X Jiang","year":"2023","unstructured":"Jiang X, Cai J, Liu L, Liu Z, Chen J, Yang C et al (2023) Predicting the unexpected total fertilization failure in conventional in vitro fertilization cycles: what is the role of semen quality? Front Cell Dev Biol 11:1133512","journal-title":"Front Cell Dev Biol"},{"key":"8033_CR11","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.fertnstert.2004.08.029","volume":"83","author":"L van der Westerlaken","year":"2005","unstructured":"van der Westerlaken L, Helmerhorst F, Dieben S, Naaktgeboren N (2005) Intracytoplasmic sperm injection as a treatment for unexplained total fertilization failure or low fertilization after conventional in vitro fertilization. Fertil Steril 83:612\u2013617","journal-title":"Fertil Steril"},{"key":"8033_CR12","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.fertnstert.2013.04.038","volume":"100","author":"LNC Johnson","year":"2013","unstructured":"Johnson LNC, Sasson IE, Sammel MD, Dokras A (2013) Does intracytoplasmic sperm injection improve the fertilization rate and decrease the total fertilization failure rate in couples with well-defined unexplained infertility? A systematic review and meta-analysis. Fertil Steril 100:704\u2013711","journal-title":"Fertil Steril"},{"key":"8033_CR13","first-page":"42","volume":"16","author":"P Mostafaei","year":"2022","unstructured":"Mostafaei P, Ghaffari F, Zolfaghari Z, Vesali S (2022) Unexplained total fertilization failure after intracytoplasmic sperm injection cycles: a case-control study on predictive factors and retreatment prognosis. Int J Fertil Steril 16:42\u201348","journal-title":"Int J Fertil Steril"},{"key":"8033_CR14","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/j.fertnstert.2005.12.017","volume":"85","author":"MP Rosen","year":"2006","unstructured":"Rosen MP, Shen S, Dobson AT, Fujimoto VY, McCulloch CE, Cedars MI (2006) Oocyte degeneration after intracytoplasmic sperm injection: a multivariate analysis to assess its importance as a laboratory or clinical marker. Fertil Steril 85:1736\u20131743","journal-title":"Fertil Steril"},{"key":"8033_CR15","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.jgyn.2012.06.004","volume":"41","author":"C Fang","year":"2012","unstructured":"Fang C, Tang J, Huang R, Li LL, Zhang MF, Liang XY (2012) Comparison of IVF outcomes using conventional insemination and ICSI in ovarian cycles in which only one or two oocytes are obtained. J Gynecol Obstet Biol Reprod 41:650\u2013656","journal-title":"J Gynecol Obstet Biol Reprod"},{"key":"8033_CR16","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.fertnstert.2008.09.039","volume":"93","author":"Y-C Ou","year":"2010","unstructured":"Ou Y-C, Lan K-C, Huang F-J, Kung F-T, Lan T-H, Chang SY (2010) Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles. Fertil Steril 93:96\u2013100","journal-title":"Fertil Steril"},{"key":"8033_CR17","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.fertnstert.2019.09.035","volume":"113","author":"S Sunderam","year":"2020","unstructured":"Sunderam S, Boulet SL, Kawwass JF, Kissin DM (2020) Comparing fertilization rates from intracytoplasmic sperm injection to conventional in vitro fertilization among women of advanced age with non-male factor infertility: a meta-analysis. Fertil Steril 113:354-363.e1","journal-title":"Fertil Steril"},{"key":"8033_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2023.102625","volume":"52","author":"P Fancsovits","year":"2023","unstructured":"Fancsovits P, Lehner A, Kaszas Z, Nemes A, Dudas B, Joo K et al (2023) Intracytoplasmic sperm injection does not improve the outcome of IVF treatments in patients with advanced maternal age or low oocyte number: a randomized controlled trial. J Gynecol Obstet Hum Reprod 52:102625","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"8033_CR19","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/aja.2008.57","volume":"12","author":"WCL Ford","year":"2010","unstructured":"Ford WCL (2010) Comments on the release of the 5th edition of the WHO laboratory manual for the examination and processing of human semen. Asian J Androl 12:59\u201363","journal-title":"Asian J Androl"},{"key":"8033_CR20","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/S0015-0282(02)03178-3","volume":"78","author":"S Repping","year":"2002","unstructured":"Repping S, van Weert J-M, Mol BWJ, de Vries JWA, van der Veen F (2002) Use of the total motile sperm count to predict total fertilization failure in in vitro fertilization. Fertil Steril 78:22\u201328","journal-title":"Fertil Steril"},{"key":"8033_CR21","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1016\/j.rbmo.2011.02.001","volume":"22","author":"ALPHA","year":"2011","unstructured":"ALPHA (2011) Scientists in reproductive medicine, ESHRE special interest group embryology. Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Reprod Biomed Online 22:632\u201346","journal-title":"Reprod Biomed Online"},{"key":"8033_CR22","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1016\/S0015-0282(00)00518-5","volume":"73","author":"DK Gardner","year":"2000","unstructured":"Gardner DK, Lane M, Stevens J, Schlenker T, Schoolcraft WB (2000) Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer. Fertil Steril 73:1155\u20131158","journal-title":"Fertil Steril"},{"key":"8033_CR23","first-page":"2703","volume":"30","author":"A Maheshwari","year":"2015","unstructured":"Maheshwari A, McLernon D, Bhattacharya S (2015) Cumulative live birth rate: time for a consensus? Hum Reprod 30:2703\u20132707","journal-title":"Hum Reprod"},{"key":"8033_CR24","unstructured":"R: The R Project for Statistical Computing [Internet]. [cited 2024 Aug 19]. Available from: https:\/\/www.r-project.org\/. 30th July 2024."},{"key":"8033_CR25","first-page":"9467568","volume":"2022","author":"S Wang","year":"2022","unstructured":"Wang S, Zhang X, Bao H, Cui Y (2022) Analysis of clinical outcomes of different fertilization methods in patients with \u22643 eggs retrieved. J Healthc Eng 2022:9467568","journal-title":"J Healthc Eng"},{"key":"8033_CR26","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.jgyn.2012.06.004","volume":"41","author":"C Fang","year":"2012","unstructured":"Fang C, Tang J, Huang R, Li LL, Zhang MF, Liang XY (2012) Comparison of IVF outcomes using conventional insemination and ICSI in ovarian cycles in which only one or two oocytes are obtained. J Gynecol Obstet Biol Reprod (Paris) 41:650\u2013656","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"8033_CR27","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s11596-018-1856-7","volume":"38","author":"N Guo","year":"2018","unstructured":"Guo N, Hua X, Li Y-F, Jin L (2018) Role of ICSI in non-male factor cycles as the number of oocytes retrieved decreases from four to one. Curr Med Sci 38:131\u2013136","journal-title":"Curr Med Sci"},{"key":"8033_CR28","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1007\/s10815-015-0459-5","volume":"32","author":"IA Sfontouris","year":"2015","unstructured":"Sfontouris IA, Kolibianakis EM, Lainas GT, Navaratnarajah R, Tarlatzis BC, Lainas TG (2015) Live birth rates using conventional in vitro fertilization compared to intracytoplasmic sperm injection in Bologna poor responders with a single oocyte retrieved. J Assist Reprod Genet 32:691\u2013697","journal-title":"J Assist Reprod Genet"},{"key":"8033_CR29","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.tjog.2022.02.052","volume":"62","author":"C-Y Wu","year":"2023","unstructured":"Wu C-Y, Huang T-J, Hwu Y-M, Kuo-Kuang Lee R, Lin M-H (2023) Comparison of clinical outcomes between conventional in vitro fertilization and intracytoplasmic sperm injection in poor responders with only single oocyte retrieved. Taiwan J Obstet Gynecol 62:55\u201358","journal-title":"Taiwan J Obstet Gynecol"},{"key":"8033_CR30","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1631\/jzus.B1100370","volume":"13","author":"Q Xi","year":"2012","unstructured":"Xi Q, Zhu L, Hu J, Wu L, Zhang H (2012) Should few retrieved oocytes be as an indication for intracytoplasmic sperm injection? J Zhejiang Univ Sci B 13:717\u2013722","journal-title":"J Zhejiang Univ Sci B"},{"key":"8033_CR31","doi-asserted-by":"publisher","first-page":"hox011","DOI":"10.1093\/hropen\/hox011","volume":"2017","author":"ESHRE Special Interest Group of Embryology","year":"2017","unstructured":"ESHRE Special Interest Group of Embryology (2017) Alpha scientists in reproductive medicine. The Vienna consensus: report of an expert meeting on the development of art laboratory performance indicators. Hum Reprod Open 2017:hox011","journal-title":"Hum Reprod Open"},{"key":"8033_CR32","doi-asserted-by":"publisher","first-page":"870708","DOI":"10.3389\/fendo.2022.870708","volume":"13","author":"T Tian","year":"2022","unstructured":"Tian T, Chen L, Yang R, Long X, Li Q, Hao Y, et al. (2022) Prediction of fertilization disorders in the in vitro fertilization\/intracytoplasmic sperm injection: a retrospective study of 106,728 treatment cycles. Front Endocrinol 13:870708","journal-title":"Front Endocrinol"},{"key":"8033_CR33","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.ejogrb.2014.10.037","volume":"184","author":"M Krog","year":"2015","unstructured":"Krog M, Prior M, Carlsen E, Loft A, Forman J, Pinborg A et al (2015) Fertilization failure after IVF in 304 couples\u2013a case-control study on predictors and long-term prognosis. Eur J Obstet Gynecol Reprod Biol 184:32\u201337","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"8033_CR34","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1007\/s10815-020-01836-0","volume":"37","author":"E Bosch","year":"2020","unstructured":"Bosch E, Espin\u00f3s JJ, Fabregues F, Fontes J, Garc\u00eda-Velasco J, Ll\u00e1cer J et al (2020) Always ICSI? A SWOT analysis. J Assist Reprod Genet 37:2081\u20132092","journal-title":"J Assist Reprod Genet"},{"key":"8033_CR35","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.ceca.2013.10.006","volume":"55","author":"QV Neri","year":"2014","unstructured":"Neri QV, Lee B, Rosenwaks Z, Machaca K, Palermo GD (2014) Understanding fertilization through intracytoplasmic sperm injection (ICSI). Cell Calcium 55:24\u201337","journal-title":"Cell Calcium"},{"key":"8033_CR36","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.2527\/jas.2006-432","volume":"85","author":"AJ Watson","year":"2007","unstructured":"Watson AJ (2007) Oocyte cytoplasmic maturation: a key mediator of oocyte and embryo developmental competence. J Anim Sci 85:E1-3","journal-title":"J Anim Sci"},{"key":"8033_CR37","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a035162","volume":"11","author":"T Wakai","year":"2019","unstructured":"Wakai T, Mehregan A, Fissore RA (2019) Ca2+ Signaling and homeostasis in mammalian oocytes and eggs. Cold Spring Harb Perspect Biol 11:a035162","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"8033_CR38","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.rbmo.2017.09.016","volume":"36","author":"KJ Gonda","year":"2018","unstructured":"Gonda KJ, Domar AD, Gleicher N, Marrs RP (2018) Insights from clinical experience in treating IVF poor responders. Reprod Biomed Online 36:12\u201319","journal-title":"Reprod Biomed Online"},{"key":"8033_CR39","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1016\/j.fertnstert.2007.06.017","volume":"90","author":"JE Johnson","year":"2008","unstructured":"Johnson JE, Higdon HL, Boone WR (2008) Effect of human granulosa cell co-culture using standard culture media on the maturation and fertilization potential of immature human oocytes. Fertil Steril 90:1674\u20131679","journal-title":"Fertil Steril"},{"key":"8033_CR40","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1093\/humrep\/dead155","volume":"38","author":"X Lu","year":"2023","unstructured":"Lu X, Lv X, Dong X, Li Y, Turathum B, Liu S et al (2023) Increased serine synthesis in cumulus cells of young infertile women with diminished ovarian reserve. Hum Reprod 38:1723\u20131732","journal-title":"Hum Reprod"},{"key":"8033_CR41","doi-asserted-by":"publisher","first-page":"5349","DOI":"10.3390\/ijms25105349","volume":"25","author":"D Del Bianco","year":"2024","unstructured":"Del Bianco D, Gentile R, Sallicandro L, Biagini A, Quellari PT, Gliozheni E et al (2024) Electro-metabolic coupling of cumulus-oocyte complex. Int J Mol Sci 25:5349","journal-title":"Int J Mol Sci"},{"key":"8033_CR42","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/403531","volume":"2012","author":"C Patrat","year":"2012","unstructured":"Patrat C, Kaffel A, Delaroche L, Guibert J, Jouannet P, Epelboin S et al (2012) Optimal timing for oocyte denudation and intracytoplasmic sperm injection. Obstet Gynecol Int 2012:403531","journal-title":"Obstet Gynecol Int"},{"key":"8033_CR43","doi-asserted-by":"publisher","first-page":"2226","DOI":"10.1093\/humrep\/deaa211","volume":"35","author":"M Carvalho","year":"2020","unstructured":"Carvalho M, Leal F, Mota S, Aguiar A, Sousa S, Nunes J et al (2020) The effect of denudation and injection timing in the reproductive outcomes of ICSI cycles: new insights into the risk of in vitro oocyte ageing. Hum Reprod 35:2226\u20132236","journal-title":"Hum Reprod"},{"key":"8033_CR44","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/S1472-6483(10)61649-5","volume":"8","author":"A Isiklar","year":"2004","unstructured":"Isiklar A, Mercan R, Balaban B, Alatas C, Aksoy S, Urman B (2004) Impact of oocyte pre-incubation time on fertilization, embryo quality and pregnancy rate after intracytoplasmic sperm injection. Reprod Biomed Online 8:682\u2013686","journal-title":"Reprod Biomed Online"},{"key":"8033_CR45","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1023\/A:1025476910771","volume":"20","author":"JY-P Ho","year":"2003","unstructured":"Ho JY-P, Chen M-J, Yi Y-C, Guu H-F, Ho ES-C (2003) The effect of preincubation period of oocytes on nuclear maturity, fertilization rate, embryo quality, and pregnancy outcome in IVF and ICSI. J Assist Reprod Genet 20:358\u201364","journal-title":"J Assist Reprod Genet"},{"key":"8033_CR46","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1093\/humrep\/13.4.1014","volume":"13","author":"L Rienzi","year":"1998","unstructured":"Rienzi L, Ubaldi F, Anniballo R, Cerulo G, Greco E (1998) Preincubation of human oocytes may improve fertilization and embryo quality after intracytoplasmic sperm injection. Hum Reprod 13:1014\u20131019","journal-title":"Hum Reprod"},{"key":"8033_CR47","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1002\/jemt.10346","volume":"61","author":"W-H Wang","year":"2003","unstructured":"Wang W-H, Day BN, Wu G-M (2003) How does polyspermy happen in mammalian oocytes? Microsc Res Tech 61:335\u2013341","journal-title":"Microsc Res Tech"},{"key":"8033_CR48","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1111\/j.1749-6632.1985.tb37508.x","volume":"442","author":"HH van der Ven","year":"1985","unstructured":"van der Ven HH, Al-Hasani S, Diedrich K, Hamerich U, Lehmann F, Krebs D (1985) Polyspermy in in vitro fertilization of human oocytes: frequency and possible causes. Ann N Y Acad Sci 442:88\u201395","journal-title":"Ann N Y Acad Sci"},{"key":"8033_CR49","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.rbmo.2023.02.005","volume":"46","author":"JM Kemper","year":"2023","unstructured":"Kemper JM, Liu Y, Afnan M, Mol BWJ, Morbeck DE (2023) What happens to abnormally fertilized embryos? Scop Rev Reprod Biomed Online 46:802\u2013807","journal-title":"Scop Rev Reprod Biomed Online"},{"issue":"3","key":"8033_CR50","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1262\/jrd.2013-136","volume":"60","author":"A Hasegawa","year":"2014","unstructured":"Hasegawa A, Mochida K, Tomishima T, Inoue K, Ogura A (2014) Microdroplet in vitro fertilization can reduce the number of spermatozoa necessary for fertilizing oocytes. J Reprod Dev 60(3):187\u201393","journal-title":"J Reprod Dev"},{"issue":"23","key":"8033_CR51","first-page":"02416","volume":"S0140\u20136736","author":"Y Wang","year":"2024","unstructured":"Wang Y, Li R, Yang R, Zheng D, Zeng L, Lian Y et al (2024) Intracytoplasmic sperm injection versus conventional in-vitro fertilisation for couples with infertility with non-severe male factor: a multicentre, open-label, randomised controlled trial. Lancet S0140\u20136736(23):02416\u201302419","journal-title":"Lancet"},{"key":"8033_CR52","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.fertnstert.2020.05.032","volume":"114","author":"Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology","year":"2020","unstructured":"Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology (2020) Electronic address: asrm@asrm.org. Intracytoplasmic sperm injection (ICSI) for non-male factor indications: a committee opinion. Fertil Steril 114:239\u201345","journal-title":"Fertil Steril"},{"key":"8033_CR53","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1093\/humrep\/deae045","volume":"39","author":"N Sheibak","year":"2024","unstructured":"Sheibak N, Amjadi F, Shamloo A, Zarei F, Zandieh Z (2024) Microfluidic sperm sorting selects a subpopulation of high-quality sperm with a higher potential for fertilization. Hum Reprod 39:902\u2013911","journal-title":"Hum Reprod"},{"key":"8033_CR54","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1007\/s00404-022-06618-w","volume":"306","author":"JS Mirsanei","year":"2022","unstructured":"Mirsanei JS, Sheibak N, Zandieh Z, Mehdizadeh M, Aflatoonian R, Tabatabaei M et al (2022) Microfluidic chips as a method for sperm selection improve fertilization rate in couples with fertilization failure. Arch Gynecol Obstet 306:901\u2013910","journal-title":"Arch Gynecol Obstet"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-025-08033-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-025-08033-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-025-08033-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T15:26:27Z","timestamp":1757172387000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-025-08033-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":54,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,8]]}},"alternative-id":["8033"],"URL":"https:\/\/doi.org\/10.1007\/s00404-025-08033-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-5335385\/v1","asserted-by":"object"}]},"ISSN":["1432-0711"],"issn-type":[{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]},"assertion":[{"value":"26 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}