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Patients with a history of first trimester TOP (TOP\u2009&lt;\u200915\u00a0weeks) were compared to those who had never had a TOP. A two-step statistical approach using Chi-squared analysis and forward-step multiple logistic regression was used to explore the relationship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      4132 individuals (11.51%) had a history of first trimester TOP. Our findings suggest an association between past TOP and a higher risk for PTB (OR\u2009=\u20091.44, 95% CI [1.25\u20131.67],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). This increases with the number of TOP, six or more TOP were associated with the highest odds ratio for spontaneous PTB (OR\u2009=\u20095.21, 95% CI [1.88\u201314.46],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). The risk for PTB did not differ between methods. Furthermore, our data suggest an association between past TOP and placental retention (OR\u2009=\u20091.25, 95% CI [1.03\u20131.52],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings underscore the importance of still recognizing prior TOP as a risk factor in obstetric care. The results may inform targeted counseling and the development of preventative strategies to mitigate maternal and fetal morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-025-08242-w","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T11:44:40Z","timestamp":1768909480000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk of preterm birth and peripartal complications after first trimester termination of pregnancy: a retrospective cohort study of 35,897 singleton births"],"prefix":"10.1007","volume":"313","author":[{"given":"Caroline Helena","family":"Gabrysch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Livia","family":"Schirru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Henrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silke","family":"Wegener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"issue":"10041","key":"8242_CR1","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/s0140-6736(16)30380-4","volume":"388","author":"G Sedgh","year":"2016","unstructured":"Sedgh G, Bearak J, Singh S, Bankole A, Popinchalk A, Ganatra B, Rossier C, Gerdts C, Tun\u00e7alp \u00d6, Johnson BR Jr., Johnston HB, Alkema L (2016) Abortion incidence between 1990 and 2014: global, regional, and subregional levels and trends. 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