{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T04:06:30Z","timestamp":1773720390800,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universitat de Valencia"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to evaluate the rate and severity of allergic events associated with the use of indocyanine green (ICG) in sentinel lymph node biopsy (SLNB) for patients with early-stage vulvar cancer. The research question focused on whether ICG administration poses a significant risk of allergic reactions, especially in patients with a history of allergies to iodinated contrast.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective study after prospective multicenter recruitment endorsed by the Spanish Investigational Network Gynecologic Oncology Group. Data on patient demographics, history of allergic reactions, and ICG administration were collected. A systematic literature review was performed to assess existing studies on ICG-related allergic reactions in SLNB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 75 patients, 66 (75%) have been exposed to iodinated contrasts and 2 (3%) had a documented iodinated contrast allergy with a mild reaction. There were no intraoperative complications. During the postoperative period, there were only minor complications (15 (20.0%) grade I and 13 (17.3%) grade II of Clavien\u2013Dindo classification), and none associated with the injection of ICG or allergen-based that could be related. The systematic review of 11 studies involved 206 patients and 354 groins. The history of allergy to iodinated contrast was not recorded in any of them. We observed no patients with adverse reactions related to this tracer after peritumoral injection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest that peritumoral ICG injection for SLNB in early-stage vulvar cancer could be safe. This study reinforces the potential for ICG to be a reliable tracer in vulvar cancer staging.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-025-08244-8","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T06:47:55Z","timestamp":1768373275000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Safety of indocyanine green for lymph node mapping in early-stage vulvar cancer: multicenter evaluation and systematic review"],"prefix":"10.1007","volume":"313","author":[{"given":"Alberto Rafael","family":"Guijarro-Campillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Padilla-Iserte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e1rbara","family":"Couso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Erasun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Utrilla-Layna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Octavio","family":"Arencibia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Gilabert-Estell\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Veiga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Boldo-Roda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor","family":"Lago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anibal","family":"Nieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Domingo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"On behalf of SEGO Spain-GOG Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"8244_CR1","volume":"2","author":"A Ansink","year":"2000","unstructured":"Ansink A, van der Velden J (2000) Surgical interventions for early squamous cell carcinoma of the vulva. Cochrane Database Syst Rev 2:CD002036","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"8244_CR2","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ygyno.2015.09.077","volume":"140","author":"NC te Grootenhuis","year":"2016","unstructured":"te Grootenhuis NC, van der Zee AGJ, van Doorn HC, van der Velden J, Vergote I, Zanagnolo V et al (2016) Sentinel nodes in vulvar cancer: long-term follow-up of the GROningen INternational Study on Sentinel nodes in Vulvar cancer (GROINSS-V) I. Gynecol Oncol 140(1):8\u201314","journal-title":"Gynecol Oncol"},{"key":"8244_CR3","unstructured":"National Comprehensive Cancer Network (2020) NCCN clinical practice guidelines in oncology: Vulvar Cancer (Squamous Cell Carcinoma) (version 1.2020). 2020 (https:\/\/www.nccn.org\/professionals\/physician_gls\/default.aspx#site)."},{"issue":"7","key":"8244_CR4","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1136\/ijgc-2023-004486","volume":"33","author":"MHM Oonk","year":"2023","unstructured":"Oonk MHM, Planchamp F, Baldwin P, Mahner S, Mirza MR, Fischerov\u00e1 D et al (2023) European society of gynaecological oncology guidelines for the management of patients with vulvar cancer\u2014update 2023. Int J Gynecol Cancer 33(7):1023\u20131043","journal-title":"Int J Gynecol Cancer"},{"issue":"2","key":"8244_CR5","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.ygyno.2021.01.031","volume":"161","author":"M Koual","year":"2021","unstructured":"Koual M, Benoit L, Nguyen-Xuan H-T, Bentivegna E, Aza\u00efs H, Bats A-S (2021) Diagnostic value of indocyanine green fluorescence guided sentinel lymph node biopsy in vulvar cancer: a systematic review. Gynecol Oncol 161(2):436\u2013441","journal-title":"Gynecol Oncol"},{"key":"8244_CR6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ejogrb.2023.12.037","volume":"294","author":"AR Guijarro-Campillo","year":"2024","unstructured":"Guijarro-Campillo AR, Padilla-Iserte P, Couso B, Erasun D, Utrilla-Layna J, Arencibia O et al (2024) Accuracy of ICG compared with technetium-99 m for sentinel lymph node biopsy in vulvar cancer. Eur J Obstet Gynecol Reprod Biol 294:11\u201319","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"8244_CR7","unstructured":"PubChem Compound Summary for CID 5282412, Indocyanine green., N.C.f.B. Information., Editor. 2020."},{"key":"8244_CR8","doi-asserted-by":"publisher","first-page":"171","DOI":"10.2147\/OPTH.S234858","volume":"14","author":"J Meira","year":"2020","unstructured":"Meira J et al (2020) Immediate reactions to fluorescein and indocyanine green in retinal angiography: review of literature and proposal for patient\u2019s evaluation. Clin Ophthalmol 14:171\u2013178","journal-title":"Clin Ophthalmol"},{"key":"8244_CR9","first-page":"37","volume":"12","author":"W Chu","year":"2017","unstructured":"Chu W et al (2017) Anaphylactic shock after intravenous administration of indocyanine green during robotic partial nephrectomy. Urol Case Rep 12:37\u201338","journal-title":"Urol Case Rep"},{"issue":"1","key":"8244_CR10","doi-asserted-by":"publisher","first-page":"30155","DOI":"10.1038\/s41598-024-81903-z","volume":"14","author":"Y Jiao","year":"2024","unstructured":"Jiao Y, Liu Y, Jin M (2024) Exploring the dark side of diagnostic dyes with a focus on Indocyanine green\u2019s adverse reactions. Sci Rep 14(1):30155","journal-title":"Sci Rep"},{"issue":"2","key":"8244_CR11","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.ejso.2022.09.015","volume":"49","author":"S Rundle","year":"2023","unstructured":"Rundle S, Korompelis P, Ralte A, Bewick D, Ratnavelu N (2023) A comparison of ICG-NIR with blue dye and technetium for the detection of sentinel lymph nodes in vulvar cancer. Eur J Surg Oncol 49(2):481\u2013485","journal-title":"Eur J Surg Oncol"},{"issue":"3","key":"8244_CR12","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1016\/j.ygyno.2020.09.044","volume":"159","author":"MM Deken","year":"2020","unstructured":"Deken MM, van Doorn HC, Verver D et al (2020) Near-infrared fluorescence imaging compared to standard sentinel lymph node detection with blue dye in patients with vulvar cancer\u2014a randomized controlled trial. Gynecol Oncol 159(3):672\u2013680","journal-title":"Gynecol Oncol"},{"issue":"8","key":"8244_CR13","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1186\/s13104-015-1576-z","volume":"26","author":"A Laios","year":"2015","unstructured":"Laios A, Volpi D, Tullis ID et al (2015) A prospective pilot study of detection of sentinel lymph nodes in gynaecological cancers using a novel near infrared fluorescence imaging system. BMC Res Notes 26(8):608","journal-title":"BMC Res Notes"},{"issue":"2","key":"8244_CR14","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.ygyno.2010.10.009","volume":"120","author":"LM Crane","year":"2011","unstructured":"Crane LM, Themelis G, Arts HJ et al (2011) Intraoperative near-infrared fluorescence imaging for sentinel lymph node detection in vulvar cancer: first clinical results. Gynecol Oncol 120(2):291\u2013295","journal-title":"Gynecol Oncol"},{"key":"8244_CR15","first-page":"14","volume":"81","author":"World Medical Association Declaration of Helsinki","year":"2014","unstructured":"World Medical Association Declaration of Helsinki (2014) ethical principles for medical research involving human subjects. J Am Coll Dent 81:14\u201318","journal-title":"J Am Coll Dent"},{"issue":"4","key":"8244_CR16","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1097\/IGC.0000000000000975","volume":"27","author":"MHM Oonk","year":"2017","unstructured":"Oonk MHM, Planchamp F, Baldwin P et al (2017) European society of gynaecological oncology guidelines for the management of patients with vulvar cancer. Int J Gynecol Cancer 27(4):832\u2013837","journal-title":"Int J Gynecol Cancer"},{"issue":"6","key":"8244_CR17","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1111\/1471-0528.12173","volume":"120","author":"BE Schaafsma","year":"2013","unstructured":"Schaafsma BE, Verbeek FPR, Peters AAW et al (2013) Near-infrared fluorescence sentinel lymph node biopsy in vulvar cancer: a randomised comparison of lymphatic tracers. BJOG 120(6):758\u2013764","journal-title":"BJOG"},{"key":"8244_CR18","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1111\/all.15032","volume":"77","author":"A Muraro","year":"2022","unstructured":"Muraro A, Worm M, Alviani C et al (2022) EAACI guidelines: anaphylaxis (2021 update). Allergy 77:357\u2013377","journal-title":"Allergy"},{"key":"8244_CR19","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.jaci.2005.12.1303","volume":"117","author":"HA Sampson","year":"2006","unstructured":"Sampson HA, Mu\u00f1oz- Furlong A, Campbell RL et al (2006) Second symposium on the definition and management of anaphylaxis: summary report\u2013second National Institute of Allergy and Infectious Disease\/Food Allergy and Anaphylaxis Network Symposium. J Allergy Clin Immunol 117:391\u2013397","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"8244_CR20","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1097\/IGC.0000000000000419","volume":"25","author":"FP Verbeek","year":"2015","unstructured":"Verbeek FP, Tummers QR, Rietbergen DD et al (2015) Sentinel lymph node biopsy in vulvar cancer using combined radioactive and fluorescence guidance. Int J Gynecol Cancer 25(6):1086\u20131093","journal-title":"Int J Gynecol Cancer"},{"issue":"4","key":"8244_CR21","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1097\/IGC.0000000000000996","volume":"27","author":"P Soergel","year":"2017","unstructured":"Soergel P, Hertel H, Nacke AK et al (2017) Sentinel lymphadenectomy in vulvar cancer using near-infrared fluorescence from indocyanine green compared with technetium 99m nanocolloid. Int J Gynecol Cancer 27(4):805\u2013812","journal-title":"Int J Gynecol Cancer"},{"key":"8244_CR22","doi-asserted-by":"crossref","unstructured":"Siegenthaler F, Imboden S, Papadia A, Mueller M (2019) P188 Sentinel lymph node mapping in vulvar cancer\u2014a new approach with indocyanine green and near infrared fluorescence imaging. Number of pages. ESGO congress","DOI":"10.1136\/ijgc-2019-ESGO.245"},{"issue":"3","key":"8244_CR23","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s00404-019-05415-2","volume":"301","author":"S Prader","year":"2020","unstructured":"Prader S, du Bois A, Harter P et al (2020) Sentinel lymph node mapping with fluorescent and radioactive tracers in vulvar cancer patients. Arch Gynecol Obstet 301(3):729\u2013736","journal-title":"Arch Gynecol Obstet"},{"issue":"11","key":"8244_CR24","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.652458","volume":"22","author":"F Siegenthaler","year":"2021","unstructured":"Siegenthaler F, Imboden S, Knabben L, Mohr S, Papadia A, Mueller MD (2021) Exploratory study of the clinical value of near-infrared sentinel lymph node mapping with indocyanine green in vulvar cancer patients. Front Oncol 22(11):652458","journal-title":"Front Oncol"},{"key":"8244_CR25","doi-asserted-by":"crossref","unstructured":"Fais G, Altieri A, Carboni G, et al (2022) 2022-RA-1155-ESGO Feasibility of and assisted laparoscopic sentinel node biopsy in vulvar cancer using combined radioactive and fluorescence guidance. Number of pages. ESGO congress","DOI":"10.1136\/ijgc-2022-ESGO.953"},{"key":"8244_CR26","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.ygyno.2025.03.039","volume":"196","author":"KMC Cornel","year":"2025","unstructured":"Cornel KMC, Mehta MP, Swift BE et al (2025) The use of indocyanine green (ICG) for sentinel lymph node detection in vulvar cancer. Gynecol Oncol 196:146\u2013151","journal-title":"Gynecol Oncol"},{"key":"8244_CR27","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, Elbers RG et al (2019) RoB 2: a revised tool for assessing risk of bias in randomisedtrials. BMJ 366:l4898","journal-title":"BMJ"},{"key":"8244_CR28","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919","volume":"355","author":"JAC Sterne","year":"2016","unstructured":"Sterne JAC, Hern\u00e1n MA, Reeves B et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomized studiesof interventions. BMJ 355:i4919","journal-title":"BMJ"},{"issue":"3","key":"8244_CR29","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/S1470-2045(17)30068-2","volume":"18","author":"EC Rossi","year":"2017","unstructured":"Rossi EC, Kowalski LD, Scalici J et al (2017) A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study. Lancet Oncol 18(3):384\u2013392","journal-title":"Lancet Oncol"},{"issue":"3","key":"8244_CR30","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.ygyno.2019.03.252","volume":"153","author":"FJ Backes","year":"2019","unstructured":"Backes FJ, Cohen D, Salani R et al (2019) Prospective clinical trial of robotic sentinel lymph node assessment with isosulfane blue (ISB) and indocyanine green (ICG) in endometrial cancer and the impact of ultrastaging (NCT01818739). Gynecol Oncol 153(3):496\u2013499","journal-title":"Gynecol Oncol"},{"issue":"1","key":"8244_CR31","doi-asserted-by":"publisher","first-page":"117.e1","DOI":"10.1016\/j.ajog.2015.12.046","volume":"215","author":"PJ Paley","year":"2016","unstructured":"Paley PJ, Veljovich DS, Press JZ et al (2016) A prospective investigation of fluorescence imaging to detect sentinel lymph nodes at robotic-assisted endometrial cancer staging. Am J Obstet Gynecol 215(1):117.e1\u20137","journal-title":"Am J Obstet Gynecol"},{"key":"8244_CR32","unstructured":"ACR Committee on Drugs and Contrast Media (2023) ACR manual on contrast media. Version ed 2023"},{"issue":"2","key":"8244_CR33","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.ygyno.2009.04.027","volume":"114","author":"A Bricou","year":"2009","unstructured":"Bricou A, Barranger E, Uzan S et al (2009) Anaphylactic shock during the sentinel lymph node procedure for cervical cancer. Gynecol Oncol 114(2):375\u2013376","journal-title":"Gynecol Oncol"},{"issue":"2","key":"8244_CR34","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.ygyno.2021.05.009","volume":"162","author":"WA Zammarrelli 3rd","year":"2021","unstructured":"Zammarrelli WA 3rd, Afonso AM, Broach V et al (2021) Sentinel lymph node biopsy in patients with endometrial cancer and an indocyanine green or iodinated contrast reaction\u2014a proposed management algorithm. Gynecol Oncol 162(2):262\u2013267","journal-title":"Gynecol Oncol"},{"key":"8244_CR35","doi-asserted-by":"crossref","unstructured":"Papadia A, Luisa Gasparri M, Mueller DM (2017) Are allergic reactions to Indocyanine green really that uncommon? A single institution experiences. Obstet Gynecol Rep","DOI":"10.15761\/OGR.1000111"},{"issue":"17","key":"8244_CR36","doi-asserted-by":"publisher","first-page":"3107","DOI":"10.3390\/cancers16173107","volume":"16","author":"J Laufer","year":"2024","unstructured":"Laufer J, Scasso S, Papadia A (2024) Impact of indocyanine green dose on sentinel lymph node mapping in cervical cancer: a systematic review. Cancers (Basel) 16(17):3107","journal-title":"Cancers (Basel)"},{"issue":"9","key":"8244_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2024.102819","volume":"53","author":"P Chauvet","year":"2024","unstructured":"Chauvet P, Jacobs A, Jaillet L, Comptour A, Pereira B, Canis M, Bourdel N (2024) Indocyanine green in gynecologic surgery: where do we stand? A literature review and meta-analysis. J Gynecol Obstet Hum Reprod 53(9):102819","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"24","key":"8244_CR38","doi-asserted-by":"publisher","first-page":"5755","DOI":"10.3390\/cancers15245755","volume":"15","author":"I Akrida","year":"2023","unstructured":"Akrida I, Michalopoulos NV, Lagadinou M, Papadoliopoulou M, Maroulis I, Mulita F (2023) An updated review on the emerging role of indocyanine green (ICG) as a sentinel lymph node tracer in breast cancer. Cancers (Basel) 15(24):5755","journal-title":"Cancers (Basel)"},{"issue":"4","key":"8244_CR39","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/j.ejso.2015.12.007","volume":"42","author":"MG Niebling","year":"2016","unstructured":"Niebling MG, Pleijhuis RG, Bastiaannet E, Brouwers AH, van Dam GM, Hoekstra HJ (2016) A systematic review and meta-analyses of sentinel lymph node identification in breast cancer and melanoma, a plea for tracer mapping. Eur J Surg Oncol 42(4):466\u2013473","journal-title":"Eur J Surg Oncol"},{"issue":"14","key":"8244_CR40","doi-asserted-by":"publisher","first-page":"2523","DOI":"10.3390\/cancers16142523","volume":"16","author":"M W\u00f6lffer","year":"2024","unstructured":"W\u00f6lffer M, Liechti R, Constantinescu M, Lese I, Zubler C (2024) Sentinel lymph node detection in cutaneous melanoma using indocyanine green-based near-infrared fluorescence imaging: a systematic review and meta-analysis. Cancers (Basel) 16(14):2523","journal-title":"Cancers (Basel)"},{"key":"8244_CR41","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1067\/mai.2002.129235","volume":"110","author":"M Wensing","year":"2002","unstructured":"Wensing M, Penninks AH, Hefle SL et al (2002) The distribution of individual threshold doses eliciting allergic reactions in a population with peanut allergy. J Allergy Clin Immunol 110:915\u2013920","journal-title":"J Allergy Clin Immunol"},{"key":"8244_CR42","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.amjmed.2007.08.025","volume":"121","author":"AD Beaty","year":"2008","unstructured":"Beaty AD, Lieberman PL, Slavin RG (2008) Seafood allergy and radiocontrast media: are physicians propagating a myth. Am J Med 121:158","journal-title":"Am J Med"},{"key":"8244_CR43","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.2214\/ajr.157.6.1950858","volume":"157","author":"WH Bush","year":"1991","unstructured":"Bush WH, Swanson DP (1991) Acute reactions to intravascular contrast media: types, risk factors, recognition, and specific treatment. AJR Am J Roentgenol 157:1153\u20131161","journal-title":"AJR Am J Roentgenol"},{"key":"8244_CR44","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1148\/radiology.183.1.1549654","volume":"183","author":"BJ Barrett","year":"1992","unstructured":"Barrett BJ, Parfrey PS, McDonald JR et al (1992) Nonionic low- osmolality versus ionic high- osmolality contrast material for intravenous use in patients perceived to be at high risk: randomized trial. Radiology 183:105\u2013110","journal-title":"Radiology"},{"key":"8244_CR45","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.molimm.2018.04.008","volume":"100","author":"T Ruethers","year":"2018","unstructured":"Ruethers T, Taki AC, Johnston EB et al (2018) Seafood allergy: a comprehensive review of fish and shellfish allergens. Mol Immunol 100:28\u201357","journal-title":"Mol Immunol"},{"issue":"1","key":"8244_CR46","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.mcna.2019.09.003","volume":"104","author":"MS Dykewicz","year":"2020","unstructured":"Dykewicz MS, Lam JK (2020) Drug hypersensitivity reactions. Med Clin North Am 104(1):109\u2013128","journal-title":"Med Clin North Am"}],"container-title":["Archives of Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-025-08244-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00404-025-08244-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00404-025-08244-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T06:47:57Z","timestamp":1768373277000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00404-025-08244-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["8244"],"URL":"https:\/\/doi.org\/10.1007\/s00404-025-08244-8","relation":{},"ISSN":["1432-0711"],"issn-type":[{"value":"1432-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,14]]},"assertion":[{"value":"1 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"There are no financial conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"41"}}