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VM was classified as mild, moderate, or severe and isolated or non\u2010isolated. Genetic, obstetric and outcome data were collected and compared according to VM categories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The incidences of associated structural anomalies were 21.9%, 53.1% and 63.9% in mild, moderate and severe VM, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.032 mild vs. moderate-severe). The incidences of genetic abnormality and fetal infection of the total VM group were 16.1% and 0.8%, respectively, with no significant differences between the VM categories (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). The incidences of pathogenic genetic variant in the mild, moderate and severe VM were 13.5% (5\/37), 16.7% (3\/18) and 38.1% (8\/21), respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.032 mild vs. severe). Fetal MRI identified additional CNS anomalies in 5.6% of cases. The incidences of surviving babies with neurological morbidities were significantly higher in fetuses with non-isolated VM groups than in isolated VM groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prognosis of fetuses with VM mostly depends on the severity and the associated anomalies. In all types of fetal VMs additional genetic investigations are valuable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-025-08279-x","type":"journal-article","created":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T02:09:08Z","timestamp":1767492548000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical characteristics and outcome of fetuses with ventriculomegaly: a retrospective multicenter study"],"prefix":"10.1007","volume":"313","author":[{"given":"Ebru Alici","family":"Davutoglu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge \u00c7etinkaya","family":"Demir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Do\u011fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niyazi Cenk","family":"Say\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oya","family":"Demirci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba Sara\u00e7","family":"Sivrikoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cihan","family":"\u0130nan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murad","family":"Gezer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Recep","family":"Has","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"At\u0131l","family":"Yuksel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riza","family":"Madazli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,3]]},"reference":[{"key":"8279_CR1","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1002\/pd.5503","volume":"39","author":"Q Chang","year":"2019","unstructured":"Chang Q, Yixian Peng Y, Qitao Huang Q et al (2019) Prognosis of fetuses with ventriculomegaly: An observational retrospective study. 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