{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T06:08:59Z","timestamp":1772431739722,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003483","name":"Hebrew University of Jerusalem","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003483","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fetal growth restriction (FGR) is a major contributor to perinatal morbidity and mortality. While guidelines address timing of delivery, the optimal mode\u2014induction of labor (IOL) versus planned cesarean delivery (CD)\u2014remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the association between planned mode of delivery and neonatal outcomes in pregnancies complicated by late onset FGR (LOFGR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study at a tertiary Canadian center (2017\u20132022). Singleton pregnancies with LOFGR (&gt;\u200934 weeks\u2019 gestation), defined by Society for Maternal\u2013Fetal Medicine (SMFM) criteria, were eligible if the last ultrasound was within 14 days of delivery. Exclusions included spontaneous labor, delivery\u2009&lt;\u200934 weeks, and contraindications to labor. Planned mode of delivery (IOL vs CD) was the exposure. Outcomes were classified as severe (perinatal death, 5-min Apgar\u2009&lt;\u20094, umbilical arterial pH\u2009&lt;\u20097.05, base deficit\u2009\u2265\u200912 mmol\/L, hypoxic-ischemic encephalopathy\/therapeutic hypothermia, grade III\u2013IV intraventricular hemorrhage, necrotizing enterocolitis, sepsis, or invasive ventilation\u2009&gt;\u200924 h) or moderate (NICU stay\u2009&gt;\u200972 h, Apgar 4\u20136, pH 7.05\u20137.10, non-invasive respiratory support\u2009&gt;\u20096\u201312 h, transient tachypnea, or brief resuscitation). Multivariable logistic regression adjusted for confounders. A prespecified subgroup applied the ISUOG criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 12,270 deliveries, 1,143 (9.3%) met SMFM criteria for LOFGR; 869 were eligible (192 planned CD, 677 IOL). Severe outcomes and moderate outcomes were more frequent after CD (23.4% vs 16.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03 and 42.2% vs 31.2%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01, respectively). IOL was associated with lower adjusted risk of severe outcomes (aOR 0.35; 95% CI 0.19\u20130.67) and moderate outcomes (aOR 0.43; 95% CI 0.24\u20130.76). Results were consistent using ISUOG criteria (aOR 0.33; 95% CI 0.17\u20130.62 and aOR 0.44; 95% CI 0.25\u20130.79, respectively) About 20% of induced patients required intrapartum CD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>IOL was associated with reduced severe and moderate neonatal morbidity compared with planned CD. IOL represents a safe alternative when intrapartum surveillance and timely operative delivery are available.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-026-08357-8","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T05:18:19Z","timestamp":1772428699000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Planned mode of delivery and neonatal outcomes in pregnancies complicated by late-onset fetal growth restriction: a retrospective cohort study"],"prefix":"10.1007","volume":"313","author":[{"given":"Misgav","family":"Rottenstreich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eran","family":"Ashwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal","family":"Yousef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryon","family":"DeFrance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon F. 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