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Eligible patients undergoing ART were randomly divided into an experimental group (receiving ZTEx intervention) and a control group (receiving sham intervention). The ZTEx intervention was delivered over 12\u00a0weeks, featuring fragmented, low-intensity exercises under professional guidance. Key indicators of endometrial health\u2014including endometrial thickness and endometrial receptivity-related parameters\u2014were monitored throughout the intervention period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 12\u00a0weeks of intervention, ANCOVA (adjusted for baseline values) revealed that the experimental group had a significantly greater endometrial thickness than the control group (6.67\u2009\u00b1\u20091.15\u00a0mm vs. 5.88\u2009\u00b1\u20091.17\u00a0mm,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Concurrently, multiple endometrial receptivity-related indices improved significantly in the experimental group (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05), including uterine artery hemodynamic parameters (pulsatility index [PI], resistance index [RI], systolic\/diastolic ratio [S\/D]) and vascularization indices (vascularization index [VI], flow index [FI], vascularization-flow index [VFI]).No exercise-related adverse events were reported over the course of the trial, confirming the safety profile of ZTEx.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Supported by rigorous statistical analyses, ZTEx effectively enhances endometrial thickness and receptivity in ART patients with thin endometrium. Its key advantages\u2014safety, feasibility, and no need for additional time or equipment\u2014make it a promising adjuvant intervention in clinical ART settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-026-08385-4","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:25:04Z","timestamp":1773667504000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of zero-time exercise intervention on endometrial receptivity in women with thin endometrium a single-center randomized sham-controlled trial"],"prefix":"10.1007","volume":"313","author":[{"given":"Zhaohui","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjiao","family":"Hua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shupei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjie","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfen","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"issue":"1","key":"8385_CR1","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.rbmo.2019.02.013","volume":"39","author":"KE Liu","year":"2019","unstructured":"Liu KE, Hartman M, Hartman A (2019) Management of thin endometrium in assisted reproduction: a clinical practice guideline from the Canadian Fertility and Andrology Society. 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