{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:59:18Z","timestamp":1776707958599,"version":"3.51.2"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Johannes Kepler University Linz"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Gynecol Obstet"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to assess current clinical practices, management, and follow-up care for women with an isolated serous tubal intraepithelial carcinoma (STIC) diagnosis in German-speaking countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      An online survey targeting all German-speaking gynecological centers was developed. The survey included single- and multiple-choice questions on hospital data, such as the number of cases per year and certification, as well as detailed questions on two scenarios: a\n                      <jats:italic>BRCA1<\/jats:italic>\n                      -positive patient undergoing prophylactic bilateral salpingo-oophorectomy and a patient with an incidental STIC finding after hysterectomy and bilateral salpingectomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      This survey was answered by 77 physicians. For a patient with a known\n                      <jats:italic>BRCA1<\/jats:italic>\n                      mutation and STIC, 89.29% of respondents would perform further diagnostics. The most frequent diagnostic steps would be a CA-125 test (83.64%) and a CT abdomen (63.64%). Further surgery would be performed by 77.78% of respondents, including 75.93% without and 5.56% with lymph node staging. 79.25% would prefer laparoscopic surgery. The majority (90.57%) would not recommend adjuvant therapy. In a patient without a known mutation and STIC, 88.46% of respondents would recommend further examinations. 58.82% would carry out genetic panel testing. Another subsequent surgery would be performed by 76.47%, with 66.67% planning to perform surgery without lymph node staging. 53.06% of respondents would follow up patients for five years. Percentages are reported based on the number of valid responses for each item.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This survey demonstrates differences in the clinical management of isolated STIC across German-speaking countries, highlighting discrepancies between guideline recommendations and real-world practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>This study is registered in the German Clinical Trials Register under<\/jats:title>\n                    <jats:p>DRKS00033112<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00404-026-08442-y","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:25:04Z","timestamp":1776705904000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of incidental STIC lesions with and without BRCA mutations: a survey of current clinical practice in Austria, Germany, and Switzerland"],"prefix":"10.1007","volume":"313","clinical-trial-number":[{"clinical-trial-number":"drks00033112","registry":"10.18810\/drks"}],"author":[{"given":"Natalia Anna","family":"Kaufmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Oppelt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Grimm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Lastinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Eichinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Trautner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Hartl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Raidl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dariga","family":"Ramazanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline Ines","family":"Preuss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"issue":"4","key":"8442_CR1","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1002\/path.1000","volume":"195","author":"JM Piek","year":"2001","unstructured":"Piek JM, van Diest PJ, Zweemer RP, Jansen JW, Poort-Keesom RJ, Menko FH et al (2001) Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer. 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