{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T03:25:08Z","timestamp":1785036308753,"version":"3.55.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2009,10,10]],"date-time":"2009-10-10T00:00:00Z","timestamp":1255132800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1007\/s00405-009-1112-7","type":"journal-article","created":{"date-parts":[[2009,10,9]],"date-time":"2009-10-09T14:33:40Z","timestamp":1255098820000},"page":"773-778","source":"Crossref","is-referenced-by-count":17,"title":["Paclitaxel with cisplatin in concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma"],"prefix":"10.1007","volume":"267","author":[{"given":"Xia-Yun","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Su","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Mei","family":"Ying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Ru","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Pei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai-Fu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,10,10]]},"reference":[{"key":"1112_CR1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ijrobp.2005.12.003","volume":"65","author":"JL Yi","year":"2006","unstructured":"Yi JL, Gao L, Huang XD et al (2006) Nasopharyngeal carcinoma treated by radical radiotherapy alone: ten-year experience of a single institution. Int J Radiat Oncol Biol Phys 65:161\u2013168","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1112_CR2","unstructured":"Gao JM, Zeng YX, Cui NJ et al (2005) Staging 915 cases of nasopharyngeal carcinoma after simple radical radiotherapy\u2014checkout of Fuzhou staging system (1992). Ai Zheng 24:1165\u20131172"},{"key":"1112_CR3","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.ijrobp.2004.07.702","volume":"61","author":"AW Lee","year":"2005","unstructured":"Lee AW, Sze WM, Au JS et al (2005) Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience. Int J Radiat Oncol Biol Phys 61:1107\u20131116","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1112_CR4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.radonc.2007.08.005","volume":"85","author":"XY He","year":"2007","unstructured":"He XY, Liu TF, He SQ et al (2007) Late course accelerated hyperfractionated radiotherapy of nasopharyngeal carcinoma (LCAF). Radiother Oncol 85:29\u201335","journal-title":"Radiother Oncol"},{"key":"1112_CR5","first-page":"321","volume":"16","author":"XD Zhu","year":"2007","unstructured":"Zhu XD, Wei JB, Qu S et al (2007) Comparison of remote results of conventional fractionation radiotherapy and late course accelerated hyperfractionation radiotherapy for nasopharyngeal carcinoma. Chin J Radiat Oncol 16:321\u2013324","journal-title":"Chin J Radiat Oncol"},{"key":"1112_CR6","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1200\/JCO.2004.05.173","volume":"22","author":"DL Kwong","year":"2004","unstructured":"Kwong DL, Sham JS, Au GK et al (2004) Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study. J Clin Oncol 22:2643\u20132653","journal-title":"J Clin Oncol"},{"key":"1112_CR7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/hed.10362","volume":"26","author":"DT Chua","year":"2004","unstructured":"Chua DT, Sham JS, Au GK (2004) A concurrent chemoirradiation with cisplatin followed by adjuvant chemotherapy with ifosfamide, 5-fluorouracil, and leucovorin for stage IV nasopharyngeal carcinoma. Head Neck 26:118\u2013126","journal-title":"Head Neck"},{"key":"1112_CR8","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1081\/CNV-50438","volume":"23","author":"Y Jiang","year":"2005","unstructured":"Jiang Y, Wei YQ, Luo F et al (2005) Gemcitabine and cisplatin in advanced nasopharyngeal carcinoma: a pilot study. Cancer Invest 23:123\u2013128","journal-title":"Cancer Invest"},{"key":"1112_CR9","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1200\/JCO.1998.16.4.1310","volume":"16","author":"M Al-Sarraf","year":"1998","unstructured":"Al-Sarraf M, LeBlanc M, Giri PG et al (1998) Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099. J Clin Oncol 16:1310\u20131317","journal-title":"J Clin Oncol"},{"key":"1112_CR10","doi-asserted-by":"crossref","first-page":"6966","DOI":"10.1200\/JCO.2004.00.7542","volume":"23","author":"AW Lee","year":"2005","unstructured":"Lee AW, Lau WH, Tung SY et al (2005) Preliminary results of a randomized study on therapeutic gain by concurrent chemotherapy for regionally-advanced nasopharyngeal carcinoma: NPC-9901 Trial by the Hong Kong Nasopharyngeal Cancer Study Group. J Clin Oncol 23:6966\u20136975","journal-title":"J Clin Oncol"},{"key":"1112_CR11","first-page":"348","volume":"18","author":"E Mostafa","year":"2006","unstructured":"Mostafa E, Nasar MN, Rabie NA et al (2006) Induction chemotherapy with paclitaxel and cisplatin, followed by concomitant cisplatin and radiotherapy for the treatment of locally advanced nasopharyngeal carcinoma. J Egypt Natl Canc Inst 18:348\u2013356","journal-title":"J Egypt Natl Canc Inst"},{"key":"1112_CR12","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.ijrobp.2008.09.053","volume":"74","author":"D Citrin","year":"2009","unstructured":"Citrin D, Mansueti J, Likhacheva A et al (2009) Long-term outcomes and toxicity of concurrent paclitaxel and radiotherapy for locally advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 74:1040\u20131046","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1112_CR13","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1093\/annonc\/mdm088","volume":"18","author":"SS Agarwala","year":"2007","unstructured":"Agarwala SS, Cano E, Heron DE et al (2007) Long-term outcomes with concurrent carboplatin, paclitaxel and radiation therapy for locally advanced, inoperable head and neck cancer. Ann Oncol 18:1224\u20131229","journal-title":"Ann Oncol"},{"key":"1112_CR14","doi-asserted-by":"crossref","unstructured":"Pignon JP, le Maitre A, Bourhis J (2007) Meta-analyses of chemotherapy in head and neck cancer (MACH-NC): an update. Int J Radiat Oncol Biol Phys 69:S112\u2013S114","DOI":"10.1016\/j.ijrobp.2007.04.088"},{"key":"1112_CR15","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.ygyno.2006.06.017","volume":"103","author":"PA Disilvestro","year":"2006","unstructured":"Disilvestro PA, Walker JL, Morrison A et al (2006) Radiation therapy with concomitant paclitaxel and cisplatin chemotherapy in cervical carcinoma limited to the pelvis: a phase I\/II study of the Gynecologic Oncology Group. Gynecol Oncol 103:1038\u20131042","journal-title":"Gynecol Oncol"},{"key":"1112_CR16","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.ijrobp.2004.07.714","volume":"61","author":"J Kao","year":"2005","unstructured":"Kao J, Conzen SD, jaskowiak NT et al (2005) Concomitant radiation therapy and paclitaxel for unresectable locally advanced breast cancer: results from two consecutive phase I\/II trials. Int J Radiat Oncol Biol Phys 61:1045\u20131053","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1112_CR17","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/jso.21063","volume":"98","author":"FM Hsu","year":"2008","unstructured":"Hsu FM, Lin CC, Lee JM et al (2008) Improved local control by surgery and paclitaxel-based chemoradiation for esophageal squamous cell carcinoma: results of a retrospective non-randomized study. J Surg Oncol 98:34\u201341","journal-title":"J Surg Oncol"},{"key":"1112_CR18","doi-asserted-by":"crossref","first-page":"377","DOI":"10.47102\/annals-acadmedsg.V37N5p377","volume":"37","author":"SP Yap","year":"2008","unstructured":"Yap SP, Lim WT, Foo KF et al (2008) Induction concurrent chemoradiotherapy using Paclitaxel and Carboplatin combination followed by surgery in locoregionally advanced non-small cell lung cancer\u2014Asian experience. Ann Acad Med Singapore 37:377\u2013382","journal-title":"Ann Acad Med Singapore"},{"key":"1112_CR19","doi-asserted-by":"crossref","first-page":"4800","DOI":"10.1200\/JCO.2006.07.9194","volume":"25","author":"CJ Langer","year":"2007","unstructured":"Langer CJ, Harris J, Horwitz EM et al (2007) Phase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Protocol 9911. J Clin Oncol 25:4800\u20134805","journal-title":"J Clin Oncol"},{"key":"1112_CR20","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1385\/MO:22:3:269","volume":"22","author":"G Fountzilas","year":"2005","unstructured":"Fountzilas G, Tolis C, Kalogera-Fountzila A et al (2005) Paclitaxel, cisplatin, leucovorin, and continuous infusion fluorouracil followed by concomitant chemoradiotherapy for locally advanced squamous cell carcinoma of the head and neck: a Hellenic Cooperative Oncology Group Phase II Study. Med Oncol 22:269\u2013279","journal-title":"Med Oncol"},{"key":"1112_CR21","first-page":"1285","volume":"28","author":"C Barone","year":"2008","unstructured":"Barone C, Grillo R, Dongiovanni D et al (2008) Induction chemotherapy followed by concurrent chemoradiotherapy in advanced head and neck squamous cell carcinoma. Anticancer Res 28:1285\u20131291","journal-title":"Anticancer Res"},{"key":"1112_CR22","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1097\/MLG.0b013e318175336a","volume":"118","author":"SB Hancock","year":"2008","unstructured":"Hancock SB, Krempl GA, Canfield V et al (2008) Treatment of base of tongue cancer with paclitaxel, ifosfamide, and cisplatinum induction chemotherapy followed by chemoradiotherapy. Laryngoscope 118:1357\u20131361","journal-title":"Laryngoscope"},{"key":"1112_CR23","first-page":"394","volume":"26","author":"QY Hu","year":"2007","unstructured":"Hu QY, Liu P, Wang L et al (2007) Concurrent chemoradiotherapy followed by adjuvant chemotherapy for stage III, IV a nasopharyngeal carcinoma. Ai zhen 26:394\u2013397","journal-title":"Ai zhen"},{"key":"1112_CR24","doi-asserted-by":"crossref","first-page":"3582","DOI":"10.1200\/JCO.2007.14.8841","volume":"26","author":"M Machtay","year":"2008","unstructured":"Machtay M, Moughan J, Trotti A et al (2008) Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. J Clin Oncol 26:3582\u20133589","journal-title":"J Clin Oncol"},{"key":"1112_CR25","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/hed.20683","volume":"30","author":"D Rades","year":"2008","unstructured":"Rades D, Fehlauer F, Sheikh-Sarraf M et al (2008) Toxicity of two cisplatin-based radiochemotherapy regimens for the treatment of patients with stage III\/IV head and neck cancer. Head Neck 30:235\u2013241","journal-title":"Head Neck"},{"key":"1112_CR26","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1200\/JCO.2002.08.149","volume":"20","author":"AT Chan","year":"2002","unstructured":"Chan AT, Teo PML, Ngan RK et al (2002) Concurrent chemotherapy-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: progression-free survival analysis of a phase III radiomized trial. J Clin Oncol 20:2038\u20132044","journal-title":"J Clin Oncol"},{"key":"1112_CR27","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1093\/jjco\/hyl083","volume":"36","author":"Y Demizu","year":"2006","unstructured":"Demizu Y, Sasaki R, Soejima T et al (2006) Efficacy and feasibility of cisplatin-based concurrent chemoradiotherapy for nasopharyngeal carcinoma. Jpn J Clin Oncol 36:620\u2013625","journal-title":"Jpn J Clin Oncol"},{"key":"1112_CR28","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00066-006-1543-7","volume":"182","author":"P Vaupel","year":"2006","unstructured":"Vaupel P, Mayer A, Hockel M (2006) Impact Of hemoglobin levels on tumor oxygenation: the higher, the better? Strahlenther Onkol 182:63\u201371","journal-title":"Strahlenther Onkol"},{"key":"1112_CR29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.meddos.2007.02.006","volume":"32","author":"RM Chau","year":"2007","unstructured":"Chau RM, Teo PM, Kam MK et al (2007) Dosimetric comparison between 2-dimensional radiation therapy and intensity modulated radiation therapy in treatment of advanced T-stage nasopharyngeal carcinoma: to treat less or more in the planning organ-at-risk volume of the brainstem and spinal cord. Med Dosim 32:263\u2013270","journal-title":"Med Dosim"},{"key":"1112_CR30","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.ijrobp.2004.11.002","volume":"62","author":"SA Yeh","year":"2005","unstructured":"Yeh SA, Tang Y, Lui CC et al (2005) Treatment outcomes and late complications of 849 patients with nasopharyngeal carcinoma treated with radiotherapy alone. Int J Radiat Oncol Biol Phys 62:672\u2013679","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1112_CR31","first-page":"151","volume":"15","author":"L Kong","year":"2006","unstructured":"Kong L, Zhang YW, Wu YR et al (2006) Late side reactions of longterm survivors after radiotherapy for nasopharyngeal carcinoma. Chin J Radiat Oncol 15:151\u2013156","journal-title":"Chin J Radiat Oncol"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-009-1112-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00405-009-1112-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-009-1112-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T03:19:51Z","timestamp":1685157591000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00405-009-1112-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,10]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["1112"],"URL":"https:\/\/doi.org\/10.1007\/s00405-009-1112-7","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,10]]}}}