{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T16:18:01Z","timestamp":1773245881155,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2012,1,24]],"date-time":"2012-01-24T00:00:00Z","timestamp":1327363200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1007\/s00405-012-1927-5","type":"journal-article","created":{"date-parts":[[2012,1,23]],"date-time":"2012-01-23T05:02:28Z","timestamp":1327294948000},"page":"2343-2348","source":"Crossref","is-referenced-by-count":15,"title":["Plasma RANTES and eotaxin levels are correlated with the severity of chronic rhinosinusitis"],"prefix":"10.1007","volume":"269","author":[{"given":"Pin-Zhir","family":"Chao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Ming","family":"Chou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen-Ho","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,1,24]]},"reference":[{"key":"1927_CR1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/MOO.0b013e328011bcbf","volume":"15","author":"MT Wise","year":"2007","unstructured":"Wise MT, Hagaman DD (2007) An immunological approach to chronic and recurrent sinusitis. Curr Opin Otolaryngol Head Neck Surg 15:10\u201317","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"1927_CR2","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.otohns.2006.11.011","volume":"136","author":"M Ramanathan Jr","year":"2007","unstructured":"Ramanathan M Jr, Lane AP (2007) Innate immunity of the sinonasal cavity and its role in chronic rhinosinusitis. Otolaryngol Head Neck Surg 136:348\u2013356","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1927_CR3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00130832-200302000-00001","volume":"3","author":"R Pawankar","year":"2003","unstructured":"Pawankar R (2003) Nasal polyposis an update: editorial review. Curr Opin Allergy Clin Immunol 3:1\u20136","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"1927_CR4","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/MOO.0b013e3282fb2885","volume":"16","author":"BA Otto","year":"2008","unstructured":"Otto BA, Wenzel SE (2008) The role of cytokines in chronic rhinosinusitis with nasal polyps. Curr Opin Otolaryngol Head Neck Surg 16:270\u2013274","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"1927_CR5","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1046\/j.1365-2222.1998.00380.x","volume":"28","author":"DL Hamilos","year":"1998","unstructured":"Hamilos DL, Leung DY, Huston DP, Kamil A, Wood R, Hamid Q (1998) GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP). Clin Exp Allergy 28:1145\u20131152","journal-title":"Clin Exp Allergy"},{"key":"1927_CR6","first-page":"235","volume":"45","author":"K Yoshifuku","year":"2007","unstructured":"Yoshifuku K, Matsune S, Ohori J, Sagara Y, Fukuiwa T, Kurono Y (2007) IL-4 and TNF-alpha increased the secretion of eotaxin from cultured fibroblasts of nasal polyps with eosinophil infiltration. Rhinology 45:235\u2013241","journal-title":"Rhinology"},{"key":"1927_CR7","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1111\/j.1365-2222.2004.1954.x","volume":"34","author":"M Nonaka","year":"2004","unstructured":"Nonaka M, Pawankar R, Fukumoto A, Ogihara N, Sakanushi A, Yagi T (2004) Induction of eotaxin production by interleukin-4, interleukin-13 and lipopolysaccharide by nasal fibroblasts. Clin Exp Allergy 34:804\u2013811","journal-title":"Clin Exp Allergy"},{"key":"1927_CR8","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1080\/00016480600951368","volume":"127","author":"GK Fan","year":"2007","unstructured":"Fan GK, Wang H, Takenaka H (2007) Eosinophil infiltration and activation in nasal polyposis. Acta Otolaryngol 127:521\u2013526","journal-title":"Acta Otolaryngol"},{"key":"1927_CR9","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1001\/jama.1994.03510290045035","volume":"271","author":"LJ Newman","year":"1994","unstructured":"Newman LJ, Platts-Mills TA, Phillips CD, Hazen KC, Gross CW (1994) Chronic sinusitis. Relationship of computed tomographic findings to allergy, asthma, and eosinophilia. JAMA 271:363\u2013367","journal-title":"JAMA"},{"key":"1927_CR10","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/0091-6749(93)90267-J","volume":"91","author":"AE Stoop","year":"1993","unstructured":"Stoop AE, van der Heijden HA, Biewenga J, van der Baan S (1993) Eosinophils in nasal polyps and nasal mucosa: an immunohistochemical study. J Allergy Clin Immunol 91:616\u2013622","journal-title":"J Allergy Clin Immunol"},{"key":"1927_CR11","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1097\/01.mlg.0000147917.43615.c0","volume":"114","author":"SE Kountakis","year":"2004","unstructured":"Kountakis SE, Arango P, Bradley D, Wade ZK, Borish L (2004) Molecular and cellular staging for the severity of chronic rhinosinusitis. Laryngoscope 114:1895\u20131905","journal-title":"Laryngoscope"},{"key":"1927_CR12","first-page":"171","volume":"35","author":"J Bartels","year":"1997","unstructured":"Bartels J, Maune S, Meyer JE, Kulke R, Schl\u00fcter C, R\u00f6wert J, Christophers E, Schr\u00f6der JM (1997) Increased eotaxin-mRNA expression in non-atopic and atopic nasal polyps: comparison to RANTES and MCP-3 expression. Rhinology 35:171\u2013174","journal-title":"Rhinology"},{"key":"1927_CR13","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s11882-001-0017-3","volume":"1","author":"JM Bernstein","year":"2001","unstructured":"Bernstein JM (2001) The molecular biology of nasal polyposis. Curr Allergy Asthma Rep 1:262\u2013267","journal-title":"Curr Allergy Asthma Rep"},{"key":"1927_CR14","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1097\/00005537-200008000-00025","volume":"110","author":"SH Shin","year":"2000","unstructured":"Shin SH, Park JY, Jeon CH, Choi JK, Lee SH (2000) Quantitative analysis of eotaxin and RANTES messenger RNA in nasal polyps: association of tissue and nasal eosinophils. Laryngoscope 110:1353\u20131357","journal-title":"Laryngoscope"},{"key":"1927_CR15","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.jaci.2008.07.008","volume":"122","author":"N Zhang","year":"2008","unstructured":"Zhang N, Van Zele T, Perez-Novo C, Van Bruaene N, Holtappels G, DeRuyck N, Van Cauwenberge P, Bachert C (2008) Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. J Allergy Clin Immunol 122:961\u2013968","journal-title":"J Allergy Clin Immunol"},{"issue":"3 suppl","key":"1927_CR16","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0194-5998(03)01397-4","volume":"129","author":"MS Benninger","year":"2003","unstructured":"Benninger MS, Ferguson BJ, Hadley JA et al (2003) Adult chronic rhinosinusitis: definitions, diagnostics, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 129(3 suppl):S1\u2013S32","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1927_CR17","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1016\/S0194-5998(97)70005-6","volume":"117","author":"VJ Lund","year":"1997","unstructured":"Lund VJ, Kennedy DW (1997) Staging for rhinosinusitis. Otolaryngol Head Neck Surg 117:S35\u2013S40","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1927_CR18","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00020840-200402000-00008","volume":"12","author":"MG Stewart","year":"2004","unstructured":"Stewart MG, Johnson RF (2004) Chronic sinusitis: symptoms versus CT scan findings. Curr Opin Otolaryngol Head Neck Surg 12:27\u201329","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"1927_CR19","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1007\/s00330-002-1644-3","volume":"13","author":"X Pruna","year":"2003","unstructured":"Pruna X (2003) Morpho-functional evaluation of osteomeatal complex in chronic sinusitis by coronal CT. Eur Radiol 13:1461\u20131468","journal-title":"Eur Radiol"},{"key":"1927_CR20","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.otohns.2007.02.004","volume":"137","author":"C Hopkins","year":"2007","unstructured":"Hopkins C, Browne JP, Slack R, Lund V, Brown P (2007) The Lund\u2013Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict? Otolaryngol Head Neck Surg 137:555\u2013561","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1927_CR21","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1808-8694(15)31090-9","volume":"74","author":"LG Couto","year":"2008","unstructured":"Couto LG, Fernades AM, Brandao DF, Santi Neto D, Valera FC, Anselmo-Lima WT (2008) Histological aspects of rhinosinusal polyps. Braz J Otorhinolaryngol 74:207\u2013212","journal-title":"Braz J Otorhinolaryngol"},{"key":"1927_CR22","first-page":"305","volume":"70","author":"P Cauwenberge Van","year":"2008","unstructured":"Van Cauwenberge P, Van Zele T, Bachert C (2008) Chronic rhinonsinusitis and nasal polyposis: the etiopathogenesis revealed? Verh K Acad Geneeskd Belg 70:305\u2013322","journal-title":"Verh K Acad Geneeskd Belg"},{"key":"1927_CR23","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1177\/194589240301700601","volume":"17","author":"JM Bernstein","year":"2003","unstructured":"Bernstein JM, Ballow M, Schlievert PM, Rich G, Allen C, Dryja D (2003) A superantigen hypothesis for the pathogenesis of chronic hyperplastic sinusitis with massive nasal polyposis. Am J Rhinol 17:321\u2013326","journal-title":"Am J Rhinol"},{"key":"1927_CR24","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/MOO.0b013e32832ac393","volume":"17","author":"Y Chan","year":"2009","unstructured":"Chan Y, Kuhn FA (2009) An update on the classifications, diagnosis, and treatment of rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 17:204\u2013208","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"1927_CR25","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1159\/000053811","volume":"125","author":"G Lorenzo Di","year":"2001","unstructured":"Di Lorenzo G, Drago A, Esposito Pellitteri M, Candore G, Colombo A, Gervasi F, Pacor ML, Purello D\u2019Ambrosio F, Caruso C (2001) Measurement of inflammatory mediators of mast cells and eosinophils in native nasal lavage fluid in nasal polyposis. Int Arch Allergy Immunol 125:164\u2013175","journal-title":"Int Arch Allergy Immunol"},{"key":"1927_CR26","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1177\/194589240201600606","volume":"16","author":"MH Zadeh","year":"2002","unstructured":"Zadeh MH, Banthia V, Anand VK, Huang C (2002) Significance of eosinophilia in chronic rhinosinusitis. Am J Rhinol 16:313\u2013317","journal-title":"Am J Rhinol"},{"key":"1927_CR27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/194589240501900103","volume":"19","author":"JE Meyer","year":"2005","unstructured":"Meyer JE, Bartels J, G\u00f6r\u00f6gh T, Sticherling M, Rudack C, Ross DA, Maune S (2005) The role of RANTES in nasal polyposis. Am J Rhinol 19:15\u201320","journal-title":"Am J Rhinol"},{"key":"1927_CR28","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1177\/000348949810700510","volume":"107","author":"JS Allen","year":"1998","unstructured":"Allen JS, Eisma R, LaFreniere D, Leonard G, Kreutzer D (1998) Characterization of the eosinophil chemokine RANTES in nasal polyps. Ann Otol Rhinol Laryngol 107:416\u2013420","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"1927_CR29","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s00405-005-1031-1","volume":"263","author":"A Danielsen","year":"2006","unstructured":"Danielsen A, Tynning T, Brokstad KA, Olofsson J, Davidsson A (2006) Interleukin 5, IL6, IL12, IFN-gamma, RANTES and Fractalkine in human nasal polyps, turbinate mucosa and serum. Eur Arch Otorhinolaryngol 263:282\u2013289","journal-title":"Eur Arch Otorhinolaryngol"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-012-1927-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00405-012-1927-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-012-1927-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T04:51:11Z","timestamp":1593579071000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00405-012-1927-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,24]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["1927"],"URL":"https:\/\/doi.org\/10.1007\/s00405-012-1927-5","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,24]]}}}