{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T20:55:53Z","timestamp":1762808153714},"reference-count":87,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2012,6,30]],"date-time":"2012-06-30T00:00:00Z","timestamp":1341014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1007\/s00405-012-2086-4","type":"journal-article","created":{"date-parts":[[2012,6,29]],"date-time":"2012-06-29T06:46:25Z","timestamp":1340952385000},"page":"405-416","source":"Crossref","is-referenced-by-count":27,"title":["Human papillomavirus and oropharyngeal squamous cell carcinoma: what the clinician should know"],"prefix":"10.1007","volume":"270","author":[{"given":"Eric M.","family":"Genden","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian M.","family":"Sambur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marshall","family":"Posner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Rinaldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan P.","family":"Rodrigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Primo\u017e","family":"Strojan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert P.","family":"Takes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfio","family":"Ferlito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,6,30]]},"reference":[{"key":"2086_CR1","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1200\/JCO.2007.14.1713","volume":"26","author":"AK Chaturvedi","year":"2008","unstructured":"Chaturvedi AK, Engels EA, Anderson WF et al (2008) Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol 26:612\u2013619","journal-title":"J Clin Oncol"},{"issue":"Suppl 10","key":"2086_CR2","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.1002\/cncr.23745","volume":"113","author":"AB Ryerson","year":"2008","unstructured":"Ryerson AB, Peters ES, Coughlin SS et al (2008) Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998\u20132003. Cancer 113(Suppl 10):2901\u20132909","journal-title":"Cancer"},{"key":"2086_CR3","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1093\/jnci\/djm233","volume":"99","author":"KM Applebaum","year":"2007","unstructured":"Applebaum KM, Furniss CS, Zeka A et al (2007) Lack of association of alcohol and tobacco with HPV16-associated head and neck cancer. J Natl Cancer Inst 99:1801\u20131810","journal-title":"J Natl Cancer Inst"},{"key":"2086_CR4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/01.OLQ.0000105327.40288.DB","volume":"31","author":"EM Smith","year":"2004","unstructured":"Smith EM, Ritchie JM, Yankowitz J et al (2004) Human papillomavirus prevalence and types in newborns and parents: concordance and modes of transmission. Sex Transm Dis 31:57\u201362","journal-title":"Sex Transm Dis"},{"key":"2086_CR5","first-page":"507","volume":"2","author":"DA Rigoni-Stern","year":"1842","unstructured":"Rigoni-Stern DA (1842) Fatti statistici relativi alle malattie cancerose. Giornale per Servire ai Progressi della Patologia e della Terapia 2:507\u2013517","journal-title":"Giornale per Servire ai Progressi della Patologia e della Terapia"},{"key":"2086_CR6","first-page":"376","volume":"47","author":"B Bafverstedt","year":"1967","unstructured":"Bafverstedt B (1967) Condylomata acuminata\u2014past and present. Acta Derm Venereol 47:376\u2013381","journal-title":"Acta Derm Venereol"},{"key":"2086_CR7","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1084\/jem.60.6.701","volume":"60","author":"P Rous","year":"1934","unstructured":"Rous P, Beard JW (1934) A virus-induced mammalian growth with the characters of a tumor (the shope rabbit papilloma): I. The growth on implantation within favorable hosts. J Exp Med 60:701\u2013722","journal-title":"J Exp Med"},{"key":"2086_CR8","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1073\/pnas.73.4.1310","volume":"73","author":"L Gissmann","year":"1976","unstructured":"Gissmann L, zur Hausen H (1976) Human papilloma virus DNA: physical mapping and genetic heterogeneity. Proc Natl Acad Sci USA 73:1310\u20131313","journal-title":"Proc Natl Acad Sci USA"},{"key":"2086_CR9","first-page":"794","volume":"36","author":"H zur Hausen","year":"1976","unstructured":"zur Hausen H (1976) Condylomata acuminata and human genital cancer. Cancer Res 36:794","journal-title":"Cancer Res"},{"key":"2086_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-642-66800-5_1","volume":"78","author":"H zur Hausen","year":"1977","unstructured":"zur Hausen H (1977) Human papillomaviruses and their possible role in squamous cell carcinomas. Curr Top Microbiol Immunol 78:1\u201330","journal-title":"Curr Top Microbiol Immunol"},{"issue":"Suppl 1","key":"2086_CR11","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/j.jcv.2004.12.006","volume":"32","author":"J Doorbar","year":"2005","unstructured":"Doorbar J (2005) The papillomavirus life cycle. J Clin Virol 32(Suppl 1):S7\u2013S15","journal-title":"J Clin Virol"},{"key":"2086_CR12","doi-asserted-by":"crossref","first-page":"5201","DOI":"10.1038\/sj.onc.1206554","volume":"22","author":"F Fehrmann","year":"2003","unstructured":"Fehrmann F, Laimins LA (2003) Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation. Oncogene 22:5201\u20135207","journal-title":"Oncogene"},{"key":"2086_CR13","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S1473-3099(09)70108-2","volume":"9","author":"MH Einstein","year":"2009","unstructured":"Einstein MH, Schiller JT, Viscidi RP et al (2009) Clinician\u2019s guide to human papillomavirus immunology: knowns and unknowns. Lancet Infect Dis 9:347\u2013356","journal-title":"Lancet Infect Dis"},{"issue":"Suppl 2","key":"2086_CR14","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/S1201-9712(07)60016-2","volume":"11","author":"I Frazer","year":"2007","unstructured":"Frazer I (2007) Correlating immunity with protection for HPV infection. Int J Infect Dis 11(Suppl 2):S10\u2013S16","journal-title":"Int J Infect Dis"},{"key":"2086_CR15","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1086\/604729","volume":"200","author":"LE Markowitz","year":"2009","unstructured":"Markowitz LE, Sternberg M, Dunne EF et al (2009) Seroprevalence of human papillomavirus types 6, 11, 16, and 18 in the United States: National Health and Nutrition Examination Survey 2003\u20132004. J Infect Dis 200:1059\u20131067","journal-title":"J Infect Dis"},{"key":"2086_CR16","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1038\/sj.bjc.6603653","volume":"96","author":"NW Bulkmans","year":"2007","unstructured":"Bulkmans NW, Berkhof J, Bulk S et al (2007) High-risk HPV type-specific clearance rates in cervical screening. Br J Cancer 96:1419\u20131424","journal-title":"Br J Cancer"},{"key":"2086_CR17","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1158\/1055-9965.EPI-03-0166","volume":"13","author":"RP Viscidi","year":"2004","unstructured":"Viscidi RP, Schiffman M, Hildesheim A et al (2004) Seroreactivity to human papillomavirus (HPV) types 16, 18, or 31 and risk of subsequent HPV infection: results from a population-based study in Costa Rica. Cancer Epidemiol Biomarkers Prev 13:324\u2013327","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2086_CR18","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1158\/1055-9965.283.14.1","volume":"14","author":"RP Viscidi","year":"2005","unstructured":"Viscidi RP, Snyder B, Cu-Uvin S et al (2005) Human papillomavirus capsid antibody response to natural infection and risk of subsequent HPV infection in HIV-positive and HIV-negative women. Cancer Epidemiol Biomarkers Prev 14:283\u2013288","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2086_CR19","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1136\/sti.78.2.135","volume":"78","author":"S Strauss","year":"2002","unstructured":"Strauss S, Sastry P, Sonnex C et al (2002) Contamination of environmental surfaces by genital human papillomaviruses. Sex Transm Infect 78:135\u2013138","journal-title":"Sex Transm Infect"},{"key":"2086_CR20","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1136\/sti.79.5.426-a","volume":"79","author":"S Strauss","year":"2003","unstructured":"Strauss S, Stephen H, Sonnex C et al (2003) Contamination of environmental surfaces by genital human papillomaviruses (HPV): a follow up study. Sex Transm Infect 79:426\u2013427","journal-title":"Sex Transm Infect"},{"key":"2086_CR21","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00007435-199505000-00009","volume":"22","author":"CF Turner","year":"1995","unstructured":"Turner CF, Danella RD, Rogers SM (1995) Sexual behavior in the United States 1930\u20131990: trends and methodological problems. Sex Transm Dis 22:173\u2013190","journal-title":"Sex Transm Dis"},{"key":"2086_CR22","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1086\/597755","volume":"199","author":"G D\u2019Souza","year":"2009","unstructured":"D\u2019Souza G, Agrawal Y, Halpern J et al (2009) Oral sexual behaviors associated with prevalent oral human papillomavirus infection. J Infect Dis 199:1263\u20131269","journal-title":"J Infect Dis"},{"key":"2086_CR23","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/jama.2012.101","volume":"307","author":"ML Gillison","year":"2012","unstructured":"Gillison ML, Broutian T, Pickard RKL et al (2012) Prevalence of oral HPV infection in the United States, 2009\u20132010. JAMA 307:693\u2013703","journal-title":"JAMA"},{"key":"2086_CR24","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00007435-199017010-00004","volume":"17","author":"K Syrj\u00e4nen","year":"1990","unstructured":"Syrj\u00e4nen K, Hakama M, Saarikoski S et al (1990) Prevalence, incidence, and estimated life-time risk of cervical human papillomavirus infections in a nonselected Finnish female population. Sex Transm Dis 17:15\u201319","journal-title":"Sex Transm Dis"},{"issue":"Suppl 10","key":"2086_CR25","first-page":"5","volume":"26","author":"FX Bosch","year":"2008","unstructured":"Bosch FX (2008) A scientific response to prevent cervical cancer in the world. Vaccine 26(Suppl 10):5\u20136","journal-title":"Vaccine"},{"key":"2086_CR26","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/EDE.0b013e3181c1e70b","volume":"21","author":"AN Burchell","year":"2010","unstructured":"Burchell AN, Tellier PP, Hanley J et al (2010) Human papillomavirus infections among couples in new sexual relationships. Epidemiology 21:31\u201337","journal-title":"Epidemiology"},{"key":"2086_CR27","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/jnci\/djq001","volume":"102","author":"AC Rodriguez","year":"2010","unstructured":"Rodriguez AC, Schiffman M, Herrero R et al (2010) Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2\/3: critical role of duration of infection. J Natl Cancer Inst 102:315\u2013324","journal-title":"J Natl Cancer Inst"},{"key":"2086_CR28","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S1473-3099(07)70158-5","volume":"7","author":"S Sanjos\u00e9 de","year":"2007","unstructured":"de Sanjos\u00e9 S, Diaz M, Castellsagu\u00e9 X et al (2007) Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis. Lancet Infect Dis 7:453\u2013459","journal-title":"Lancet Infect Dis"},{"issue":"Suppl 6","key":"2086_CR29","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jadohealth.2005.09.011","volume":"37","author":"AB Moscicki","year":"2005","unstructured":"Moscicki AB (2005) Impact of HPV infection in adolescent populations. J Adolesc Health 37(Suppl 6):S3\u2013S9","journal-title":"J Adolesc Health"},{"key":"2086_CR30","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1002\/cncr.2820360933","volume":"36","author":"GR Newell","year":"1975","unstructured":"Newell GR, Krementz ET, Roberts JD (1975) Excess occurrence of cancer of the oral cavity, lung, and bladder following cancer of the cervix. Cancer 36:2155\u20132158","journal-title":"Cancer"},{"key":"2086_CR31","first-page":"1","volume":"79","author":"KJ Syrj\u00e4nen","year":"1983","unstructured":"Syrj\u00e4nen KJ, Syrj\u00e4nen SM, Lamberg MA et al (1983) Human papillomavirus (HPV) involvement in squamous cell lesions of the oral cavity. Proc Finn Dent Soc 79:1\u20138","journal-title":"Proc Finn Dent Soc"},{"key":"2086_CR32","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/1523-1747.ep12265517","volume":"84","author":"T L\u00f6ning","year":"1985","unstructured":"L\u00f6ning T, Ikenberg H, Becker J et al (1985) Analysis of oral papillomas, leukoplakias, and invasive carcinomas for human papillomavirus type related DNA. J Invest Dermatol 84:417\u2013420","journal-title":"J Invest Dermatol"},{"key":"2086_CR33","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1200\/JCO.2004.00.3335","volume":"24","author":"PM Weinberger","year":"2006","unstructured":"Weinberger PM, Yu Z, Haffty BG et al (2006) Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis. J Clin Oncol 24:736\u2013747","journal-title":"J Clin Oncol"},{"key":"2086_CR34","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/ncponc0984","volume":"5","author":"A Psyrri","year":"2008","unstructured":"Psyrri A, DiMaio D (2008) Human papillomavirus in cervical and head-and-neck cancer. Nat Clin Pract Oncol 5:24\u201331","journal-title":"Nat Clin Pract Oncol"},{"key":"2086_CR35","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/jnci\/djn025","volume":"100","author":"ML Gillison","year":"2008","unstructured":"Gillison ML, D\u2019Souza G, Westra W et al (2008) Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 100:407\u2013420","journal-title":"J Natl Cancer Inst"},{"key":"2086_CR36","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1002\/lary.20294","volume":"119","author":"FP Worden","year":"2009","unstructured":"Worden FP, Moyer J, Lee JS et al (2009) Chemoselection as a strategy for organ preservation in patients with T4 laryngeal squamous cell carcinoma with cartilage invasion. Laryngoscope 119:1510\u20131517","journal-title":"Laryngoscope"},{"key":"2086_CR37","doi-asserted-by":"crossref","first-page":"c1040","DOI":"10.1136\/bmj.c1040","volume":"340","author":"M G\u00f6k","year":"2010","unstructured":"G\u00f6k M, Heideman DA, van Kemenade FJ et al (2010) HPV testing on self collected cervicovaginal lavage specimens as screening method for women who do not attend cervical screening: cohort study. BMJ 340:c1040","journal-title":"BMJ"},{"key":"2086_CR38","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1016\/j.vaccine.2010.02.098","volume":"28","author":"AM Hong","year":"2010","unstructured":"Hong AM, Grulich AE, Jones D et al (2010) Squamous cell carcinoma of the oropharynx in Australian males induced by human papillomavirus vaccine targets. Vaccine 28:3269\u20133272","journal-title":"Vaccine"},{"key":"2086_CR39","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/ijc.24339","volume":"125","author":"A N\u00e4sman","year":"2009","unstructured":"N\u00e4sman A, Attner P, Hammarstedt L et al (2009) Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma? Int J Cancer 125:362\u2013366","journal-title":"Int J Cancer"},{"key":"2086_CR40","doi-asserted-by":"crossref","unstructured":"Licitra L, Zigon G, Gatta G et al (2008) Human papillomavirus in HNSCC: a European epidemiologic perspective. Hematol Oncol Clin North Am 22:1143\u20131153, vii\u2013viii","DOI":"10.1016\/j.hoc.2008.10.002"},{"key":"2086_CR41","doi-asserted-by":"crossref","first-page":"4294","DOI":"10.1200\/JCO.2011.36.4596","volume":"29","author":"AK Chaturvedi","year":"2011","unstructured":"Chaturvedi AK, Engels EA, Pfeiffer RM et al (2011) Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 29:4294\u20134301","journal-title":"J Clin Oncol"},{"key":"2086_CR42","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.oraloncology.2003.08.015","volume":"40","author":"CD Llewellyn","year":"2004","unstructured":"Llewellyn CD, Linklater K, Bell J et al (2004) An analysis of risk factors for oral cancer in young people: a case\u2013control study. Oral Oncol 40:304\u2013313","journal-title":"Oral Oncol"},{"key":"2086_CR43","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1002\/ijc.11627","volume":"108","author":"X Castellsagu\u00e9","year":"2004","unstructured":"Castellsagu\u00e9 X, Quintana MJ, Mart\u00ednez MC et al (2004) The role of type of tobacco and type of alcoholic beverage in oral carcinogenesis. Int J Cancer 108:741\u2013749","journal-title":"Int J Cancer"},{"key":"2086_CR44","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1080\/00016480510043945","volume":"125","author":"BG Hansson","year":"2005","unstructured":"Hansson BG, Rosenquist K, Antonsson A et al (2005) Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: a population-based case-control study in southern Sweden. Acta Otolaryngol 125:1337\u20131344","journal-title":"Acta Otolaryngol"},{"key":"2086_CR45","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.amjoto.2011.02.001","volume":"33","author":"P Sinha","year":"2012","unstructured":"Sinha P, Logan HL, Mendenhall WM (2012) Human papillomavirus, smoking, and head and neck cancer. Am J Otolaryngol 33:130\u2013136","journal-title":"Am J Otolaryngol"},{"key":"2086_CR46","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1093\/jnci\/djg107","volume":"95","author":"R Herrero","year":"2003","unstructured":"Herrero R, Castellsagu\u00e9 X, Pawlita M et al (2003) Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. J Natl Cancer Inst 95:1772\u20131783","journal-title":"J Natl Cancer Inst"},{"key":"2086_CR47","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/S0140-6736(99)92824-6","volume":"354","author":"M Frisch","year":"1999","unstructured":"Frisch M, Biggar RJ (1999) Aetiological parallel between tonsillar and anogenital squamous-cell carcinomas. Lancet 354:1442\u20131443","journal-title":"Lancet"},{"key":"2086_CR48","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1006\/scbi.1999.0141","volume":"9","author":"F Stubenrauch","year":"1999","unstructured":"Stubenrauch F, Laimins LA (1999) Human papillomavirus life cycle: active and latent phases. Semin Cancer Biol 9:379\u2013386","journal-title":"Semin Cancer Biol"},{"key":"2086_CR49","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1002\/cncr.22963","volume":"110","author":"EM Sturgis","year":"2007","unstructured":"Sturgis EM, Cinciripini PM (2007) Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers? Cancer 110:1429\u20131435","journal-title":"Cancer"},{"key":"2086_CR50","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1002\/ijc.22464","volume":"120","author":"SH Kim","year":"2007","unstructured":"Kim SH, Koo BS, Kang S et al (2007) HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c-myc during tumor formation. Int J Cancer 120:1418\u20131425","journal-title":"Int J Cancer"},{"key":"2086_CR51","doi-asserted-by":"crossref","first-page":"5694","DOI":"10.1158\/1078-0432.CCR-05-0587","volume":"11","author":"S Begum","year":"2005","unstructured":"Begum S, Cao D, Gillison M et al (2005) Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma. Clin Cancer Res 11:5694\u20135699","journal-title":"Clin Cancer Res"},{"key":"2086_CR52","doi-asserted-by":"crossref","first-page":"5526","DOI":"10.1128\/JCM.43.11.5526-5535.2005","volume":"43","author":"G D\u2019Souza","year":"2005","unstructured":"D\u2019Souza G, Sugar E, Ruby W et al (2005) Analysis of the effect of DNA purification on detection of human papillomavirus in oral rinse samples by PCR. J Clin Microbiol 43:5526\u20135535","journal-title":"J Clin Microbiol"},{"key":"2086_CR53","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1600-0714.1992.tb01008.x","volume":"21","author":"G Lawton","year":"1992","unstructured":"Lawton G, Thomas S, Schonrock J et al (1992) Human papillomaviruses in normal oral mucosa: a comparison of methods for sample collection. J Oral Pathol Med 21:265\u2013269","journal-title":"J Oral Pathol Med"},{"key":"2086_CR54","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1158\/1940-6207.CAPR-11-0284","volume":"4","author":"C Fakhry","year":"2011","unstructured":"Fakhry C, Rosenthal BT, Clark DP et al (2011) Associations between oral HPV16 infection and cytopathology: evaluation of an oropharyngeal \u201cpap-test equivalent\u201d in high-risk populations. Cancer Prev Res (Phila) 4:1378\u20131384","journal-title":"Cancer Prev Res (Phila)"},{"key":"2086_CR55","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1056\/NEJMoa065497","volume":"356","author":"G D\u2019Souza","year":"2007","unstructured":"D\u2019Souza G, Kreimer AR, Viscidi R et al (2007) Case\u2013control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 356:1944\u20131956","journal-title":"N Engl J Med"},{"key":"2086_CR56","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/00008469-200012000-00010","volume":"9","author":"K Hemminki","year":"2000","unstructured":"Hemminki K, Dong C, Frisch M (2000) Tonsillar and other upper aerodigestive tract cancers among cervical cancer patients and their husbands. Eur J Cancer Prev 9:433\u2013437","journal-title":"Eur J Cancer Prev"},{"key":"2086_CR57","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1002\/cncr.20998","volume":"103","author":"CH Shiboski","year":"2005","unstructured":"Shiboski CH, Schmidt BL, Jordan RC (2005) Tongue and tonsil carcinoma: increasing trends in the US population ages 20\u201344\u00a0years. Cancer 103:1843\u20131849","journal-title":"Cancer"},{"key":"2086_CR58","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1002\/ijc.22177","volume":"119","author":"L Hammarstedt","year":"2006","unstructured":"Hammarstedt L, Lindquist D, Dahlstrand H et al (2006) Human papillomavirus as a risk factor for the increase in incidence of tonsillar cancer. Int J Cancer 119:2620\u20132623","journal-title":"Int J Cancer"},{"key":"2086_CR59","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.radonc.2010.04.022","volume":"95","author":"P Lassen","year":"2010","unstructured":"Lassen P (2010) The role of Human papillomavirus in head and neck cancer and the impact on radiotherapy outcome. Radiother Oncol 95:371\u2013380","journal-title":"Radiother Oncol"},{"key":"2086_CR60","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S1470-2045(10)70017-6","volume":"11","author":"S Marur","year":"2010","unstructured":"Marur S, D\u2019Souza G, Westra WH et al (2010) HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol 11:781\u2013789","journal-title":"Lancet Oncol"},{"key":"2086_CR61","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/jcp.2003.008656","volume":"57","author":"S Syrj\u00e4nen","year":"2004","unstructured":"Syrj\u00e4nen S (2004) HPV infections and tonsillar carcinoma. J Clin Pathol 57:449\u2013455","journal-title":"J Clin Pathol"},{"key":"2086_CR62","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1158\/1055-9965.EPI-08-0151","volume":"17","author":"AR Giuliano","year":"2008","unstructured":"Giuliano AR, Lazcano-Ponce E, Villa LL et al (2008) The human papillomavirus infection in men study: human papillomavirus prevalence and type distribution among men residing in Brazil, Mexico, and the United States. Cancer Epidemiol Biomarkers Prev 17:2036\u20132043","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2086_CR63","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1086\/591095","volume":"198","author":"AR Giuliano","year":"2008","unstructured":"Giuliano AR, Lu B, Nielson CM et al (2008) Age-specific prevalence, incidence, and duration of human papillomavirus infections in a cohort of 290 US men. J Infect Dis 198:827\u2013835","journal-title":"J Infect Dis"},{"key":"2086_CR64","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jcv.2005.05.012","volume":"35","author":"M Rintala","year":"2006","unstructured":"Rintala M, Gr\u00e9nman S, Puranen M et al (2006) Natural history of oral papillomavirus infections in spouses: a prospective Finnish HPV Family Study. J Clin Virol 35:89\u201394","journal-title":"J Clin Virol"},{"key":"2086_CR65","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1542\/peds.2006-0461","volume":"118","author":"SL Block","year":"2006","unstructured":"Block SL, Nolan T, Sattler C et al (2006) Comparison of the immunogenicity and reactogenicity of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in male and female adolescents and young adult women. Pediatrics 118:2135\u20132145","journal-title":"Pediatrics"},{"key":"2086_CR66","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1056\/NEJMoa061760","volume":"356","author":"SM Garland","year":"2007","unstructured":"Garland SM, Hernandez-Avila M, Wheeler CM et al (2007) Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases. N Engl J Med 356:1928\u20131943","journal-title":"N Engl J Med"},{"key":"2086_CR67","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1067\/j.cpsurg.2008.10.003","volume":"46","author":"U Duvvuri","year":"2009","unstructured":"Duvvuri U, Myers JN (2009) Contemporary management of oropharyngeal cancer: anatomy and physiology of the oropharynx. Curr Probl Surg 46:119\u2013184","journal-title":"Curr Probl Surg"},{"key":"2086_CR68","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.oraloncology.2010.02.013","volume":"46","author":"M Robinson","year":"2010","unstructured":"Robinson M, Sloan P, Shaw R (2010) Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing. Oral Oncol 46:492\u2013496","journal-title":"Oral Oncol"},{"key":"2086_CR69","doi-asserted-by":"crossref","first-page":"6262","DOI":"10.1158\/1078-0432.CCR-11-0388","volume":"17","author":"AG Schache","year":"2011","unstructured":"Schache AG, Liloglou T, Risk JM et al (2011) Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clin Cancer Res 17:6262\u20136271","journal-title":"Clin Cancer Res"},{"key":"2086_CR70","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1002\/ijc.22980","volume":"121","author":"SJ Smeets","year":"2007","unstructured":"Smeets SJ, Hesselink AT, Speel EJ et al (2007) A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen. Int J Cancer 121:2465\u20132472","journal-title":"Int J Cancer"},{"key":"2086_CR71","doi-asserted-by":"crossref","unstructured":"Strojan P, Ferlito A, Medina JE et al (2011) Contemporary management of lymph node metastases from an unknown primary to the neck: I. A review of diagnostic approaches. Head Neck (Epub ahead of print)","DOI":"10.1002\/hed.21898"},{"key":"2086_CR72","doi-asserted-by":"crossref","first-page":"665","DOI":"10.6004\/jnccn.2011.0055","volume":"9","author":"EM Sturgis","year":"2011","unstructured":"Sturgis EM, Ang KK (2011) The epidemic of HPV-associated oropharyngeal cancer is here: is it time to change our treatment paradigms? J Natl Compr Canc Netw 9:665\u2013673","journal-title":"J Natl Compr Canc Netw"},{"key":"2086_CR73","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1093\/jnci\/djq403","volume":"102","author":"J Peres","year":"2010","unstructured":"Peres J (2010) HPV-positive oropharyngeal cancer: data may justify new approach. J Natl Cancer Inst 102:1456\u20131459","journal-title":"J Natl Cancer Inst"},{"key":"2086_CR74","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1002\/lary.21845","volume":"121","author":"EM Genden","year":"2011","unstructured":"Genden EM, Kotz T, Tong CC et al (2011) Transoral robotic resection and reconstruction for head and neck cancer. Laryngoscope 121:1668\u20131674","journal-title":"Laryngoscope"},{"key":"2086_CR75","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1177\/0194599811402172","volume":"145","author":"A Hurtuk","year":"2011","unstructured":"Hurtuk A, Agrawal A, Old M et al (2011) Outcomes of transoral robotic surgery: a preliminary clinical experience. Otolaryngol Head Neck Surg 145:248\u2013253","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2086_CR76","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/hed.21500","volume":"33","author":"MA Cohen","year":"2011","unstructured":"Cohen MA, Weinstein GS, O\u2019Malley BW Jr et al (2011) Transoral robotic surgery and human papillomavirus status: oncologic results. Head Neck 33:573\u2013580","journal-title":"Head Neck"},{"key":"2086_CR77","unstructured":"Stucken C, de Almeida JR, Tong CCL, Genden EM (2012) Transoral robotic surgery for smokers with squamous cell carcinoma of the oropharynx. In: Multidisciplinary Head and Neck Cancer Symposium, Phoenix, AZ"},{"key":"2086_CR78","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1002\/hed.21669","volume":"33","author":"BH Haughey","year":"2011","unstructured":"Haughey BH, Hinni ML, Salassa JR et al (2011) Transoral laser microsurgery as primary treatment for advanced-stage oropharyngeal cancer: a United States multicenter study. Head Neck 33:1683\u20131694","journal-title":"Head Neck"},{"key":"2086_CR79","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1038\/sj.bjc.6605944","volume":"103","author":"AM Hong","year":"2010","unstructured":"Hong AM, Dobbins TA, Lee CS et al (2010) Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy. Br J Cancer 103:1510\u20131517","journal-title":"Br J Cancer"},{"key":"2086_CR80","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1002\/ijc.24842","volume":"126","author":"CA Fischer","year":"2010","unstructured":"Fischer CA, Zlobec I, Green E et al (2010) Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality? Int J Cancer 126:1256\u20131262","journal-title":"Int J Cancer"},{"key":"2086_CR81","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/ijc.22851","volume":"121","author":"CC Ragin","year":"2007","unstructured":"Ragin CC, Taioli E (2007) Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: review and meta-analysis. Int J Cancer 121:1813\u20131820","journal-title":"Int J Cancer"},{"key":"2086_CR82","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1056\/NEJMoa0912217","volume":"363","author":"KK Ang","year":"2010","unstructured":"Ang KK, Harris J, Wheeler R et al (2010) Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 363:24\u201335","journal-title":"N Engl J Med"},{"key":"2086_CR83","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1002\/ijc.23458","volume":"122","author":"HC Hafkamp","year":"2008","unstructured":"Hafkamp HC, Manni JJ, Haesevoets A et al (2008) Marked differences in survival rate between smokers and nonsmokers with HPV16-associated tonsillar carcinomas. Int J Cancer 122:2656\u20132664","journal-title":"Int J Cancer"},{"key":"2086_CR84","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1158\/1078-0432.CCR-09-2350","volume":"16","author":"JH Maxwell","year":"2010","unstructured":"Maxwell JH, Kumar B, Feng FY et al (2010) Tobacco use in human papillomavirus-positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrence. Clin Cancer Res 16:1226\u20131235","journal-title":"Clin Cancer Res"},{"key":"2086_CR85","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.1200\/JCO.2010.29.2904","volume":"28","author":"D Rischin","year":"2010","unstructured":"Rischin D, Young RJ, Fisher R et al (2010) Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial. J Clin Oncol 28:4142\u20134148","journal-title":"J Clin Oncol"},{"key":"2086_CR86","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1177\/000348940911800509","volume":"118","author":"OC Ukpo","year":"2009","unstructured":"Ukpo OC, Pritchett CV, Lewis JE et al (2009) Human papillomavirus-associated oropharyngeal squamous cell carcinomas: primary tumor burden and survival in surgical patients. Ann Otol Rhinol Laryngol 118:368\u2013373","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"2086_CR87","doi-asserted-by":"crossref","unstructured":"Sinha P, Lewis JS, Piccirillo JF et al (2011) Extracapsular spread and adjuvant therapy in human papillomavirus-related, p16-positive oropharyngeal carcinoma. Cancer (Epub ahead of print)","DOI":"10.1002\/cncr.26671"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-012-2086-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00405-012-2086-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-012-2086-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T06:30:53Z","timestamp":1714113053000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00405-012-2086-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,30]]},"references-count":87,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["2086"],"URL":"https:\/\/doi.org\/10.1007\/s00405-012-2086-4","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,30]]}}}