{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T14:39:49Z","timestamp":1722609589381},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1007\/s00405-017-4550-7","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T11:18:25Z","timestamp":1491391105000},"page":"2883-2889","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Retrospective evaluation of concomitant cetuximab and radiotherapy tolerance for locoregional advanced head and neck squamous cell carcinoma treatment in patients unfit for platinum-based chemotherapy"],"prefix":"10.1007","volume":"274","author":[{"given":"Audrey","family":"Rambeau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radj","family":"Gervais","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"De Raucourt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Babin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey Emmanuelle","family":"Dugu\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Florescu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Blanchard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Gery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,4,5]]},"reference":[{"key":"4550_CR1","doi-asserted-by":"crossref","unstructured":"Calais G, Alfonsi M, Bardet E, Sire C, Germain T, Bergerot P et al (1999) Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. JNCI J Natl Cancer Inst 91(24):2081\u20136","DOI":"10.1093\/jnci\/91.24.2081"},{"key":"4550_CR2","doi-asserted-by":"crossref","unstructured":"Pignon J-P, le Ma\u00eetre A, Maillard E, Bourhis J, MACH-NC Collaborative Group (2009) Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol J Eur Soc Ther Radiol Oncol 92(1):4\u201314","DOI":"10.1016\/j.radonc.2009.04.014"},{"key":"4550_CR3","unstructured":"Bonner JA, Raisch KP, Trummell HQ, Robert F, Meredith RF, Spencer SA et al (2000) Enhanced apoptosis with combination C225\/radiation treatment serves as the impetus for clinical investigation in head and neck cancers. J Clin Oncol 18(suppl_1):47s\u201353s"},{"key":"4550_CR4","doi-asserted-by":"crossref","unstructured":"Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, Cohen RB et al (2006) Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354(6):567\u201378","DOI":"10.1056\/NEJMoa053422"},{"key":"4550_CR5","doi-asserted-by":"crossref","unstructured":"Magrini SM, Buglione M, Corv\u00f2 R, Pirtoli L, Paiar F, Ponticelli P et al (2016) Cetuximab and radiotherapy versus cisplatin and radiotherapy for locally advanced head and neck cancer: a randomized phase II Trial. J Clin Oncol Off J Am Soc Clin Oncol 34(5):427\u201335","DOI":"10.1200\/JCO.2015.63.1671"},{"key":"4550_CR6","doi-asserted-by":"crossref","unstructured":"Petrelli F, Coinu A, Riboldi V, Borgonovo K, Ghilardi M, Cabiddu M et al (2014) Concomitant platinum-based chemotherapy or cetuximab with radiotherapy for locally advanced head and neck cancer: a systematic review and meta-analysis of published studies. Oral Oncol 50(11):1041\u20138","DOI":"10.1016\/j.oraloncology.2014.08.005"},{"key":"4550_CR7","doi-asserted-by":"crossref","unstructured":"Walsh L, Gillham C, Dunne M, Fraser I, Hollywood D, Armstrong J et al (2011) Toxicity of cetuximab versus cisplatin concurrent with radiotherapy in locally advanced head and neck squamous cell cancer (LAHNSCC). Radiother Oncol J Eur Soc Ther Radiol Oncol 98(1):38\u201341","DOI":"10.1016\/j.radonc.2010.11.009"},{"key":"4550_CR8","doi-asserted-by":"crossref","unstructured":"Riaz N, Sherman E, Koutcher L, Shapiro L, Katabi N, Zhang Z et al (2016) Concurrent chemoradiotherapy with cisplatin versus cetuximab for squamous cell carcinoma of the head and neck. Am J Clin Oncol 39(1):27\u201331","DOI":"10.1097\/COC.0000000000000006"},{"key":"4550_CR9","doi-asserted-by":"crossref","unstructured":"Peddi P, Shi R, Nair B, Ampil F, Mills GM, Jafri SH (2015) Cisplatin, cetuximab, and radiation in locally advanced head and neck squamous cell cancer: a retrospective review. Clin Med Insights Oncol 9:1\u20137","DOI":"10.4137\/CMO.S18682"},{"key":"4550_CR10","doi-asserted-by":"crossref","unstructured":"Ang KK, Harris J, Wheeler R, Weber R, Rosenthal DI, Nguyen-t\u00e2n PF et al (2010) Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 363(1):24\u201335","DOI":"10.1056\/NEJMoa0912217"},{"key":"4550_CR11","doi-asserted-by":"crossref","unstructured":"Vermorken JB, Psyrri A, Mes\u00eda R, Peyrade F, Beier F, de Blas B et al (2014) Impact of tumor HPV status on outcome in patients with recurrent and\/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: retrospective analysis of the phase III EXTREME trial. Ann Oncol Off J Eur Soc Med Oncol ESMO 25(4):801\u20137","DOI":"10.1093\/annonc\/mdt574"},{"key":"4550_CR12","doi-asserted-by":"crossref","unstructured":"Ou D, Levy A, Blanchard P, Nguyen F, Garberis I, Casiraghi O et al (2016) Concurrent chemoradiotherapy with cisplatin or cetuximab for locally advanced head and neck squamous cell carcinomas: does human papilloma virus play a role? Oral Oncol 59:50\u20137","DOI":"10.1016\/j.oraloncology.2016.05.019"},{"key":"4550_CR13","doi-asserted-by":"crossref","unstructured":"Pryor DI, Porceddu SV, Burmeister BH, Guminski A, Thomson DB, Shepherdson K et al (2009) Enhanced toxicity with concurrent cetuximab and radiotherapy in head and neck cancer. Radiother Oncol J Eur Soc Ther Radiol Oncol 90(2):172\u20136","DOI":"10.1016\/j.radonc.2008.09.018"},{"key":"4550_CR14","doi-asserted-by":"crossref","unstructured":"Koutcher L, Sherman E, Fury M, Wolden S, Zhang Z, Mo Q et al (2011) Concurrent cisplatin and radiation versus cetuximab and radiation for locally advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 81(4):915\u201322","DOI":"10.1016\/j.ijrobp.2010.07.008"},{"key":"4550_CR15","doi-asserted-by":"crossref","unstructured":"Kurokawa M, Watanabe Nemoto M, Harada R, Kobayashi H, Horikoshi T, Kanazawa A et al (2015) Initial experience of radiotherapy plus cetuximab for Japanese head and neck cancer patients. J Radiat Res 56(5):849\u201355","DOI":"10.1093\/jrr\/rrv038"},{"key":"4550_CR16","doi-asserted-by":"crossref","unstructured":"Denis F, Garaud P, Bardet E, Alfonsi M, Sire C, Germain T et al (2004) Final results of the 94\u201301 French head and neck oncology and radiotherapy group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma. J Clin Oncol Off J Am Soc Clin Oncol 22(1):69\u201376","DOI":"10.1200\/JCO.2004.08.021"},{"key":"4550_CR17","doi-asserted-by":"crossref","unstructured":"Levy A, Blanchard P, Bellefqih S, Brahimi N, Guigay J, Janot F et al (2014) Concurrent use of cisplatin or cetuximab with definitive radiotherapy for locally advanced head and neck squamous cell carcinomas. Strahlenther Onkol 190(9):823\u201331","DOI":"10.1007\/s00066-014-0626-0"},{"key":"4550_CR18","doi-asserted-by":"crossref","unstructured":"Lord HK, Junor E, Ironside J (2008) Cetuximab is effective, but more toxic than reported in the Bonner trial. Clin Oncol (R Coll Radiol) 20(1):96","DOI":"10.1016\/j.clon.2007.09.003"},{"key":"4550_CR19","doi-asserted-by":"crossref","unstructured":"Giro C, Berger B, B\u00f6lke E, Ciernik IF, Duprez F, Locati L et al (2009) High rate of severe radiation dermatitis during radiation therapy with concurrent cetuximab in head and neck cancer: results of a survey in EORTC institutes. Radiother Oncol J Eur Soc Ther Radiol Oncol 90(2):166\u201371","DOI":"10.1016\/j.radonc.2008.09.007"},{"key":"4550_CR20","doi-asserted-by":"crossref","unstructured":"Okano S, Yoshino T, Fujii M, Onozawa Y, Kodaira T, Fujii H et al (2013) Phase II study of cetuximab plus concomitant boost radiotherapy in Japanese patients with locally advanced squamous cell carcinoma of the head and neck. Jpn J Clin Oncol 43(5):476\u201382","DOI":"10.1093\/jjco\/hyt030"},{"key":"4550_CR21","doi-asserted-by":"crossref","unstructured":"Koutcher LD, Wolden S, Lee N (2009) Severe radiation dermatitis in patients with locally advanced head and neck cancer treated with concurrent radiation and cetuximab. Am J Clin Oncol 32(5):472\u20136","DOI":"10.1097\/COC.0b013e318193125c"},{"key":"4550_CR22","doi-asserted-by":"crossref","unstructured":"Falk AT, H\u00e9bert C, Tran A, Chand M-E, Leysalle A, Thariat J et al (2016) Radiotherapy for elderly patients and cetuximab, a monocentric study. Eur Arch Otorhinolaryngol 274(2):1061\u20135","DOI":"10.1007\/s00405-016-4336-3"},{"key":"4550_CR23","doi-asserted-by":"crossref","unstructured":"Lefebvre JL, Pointreau Y, Rolland F, Alfonsi M, Baudoux A, Sire C et al (2013) Induction chemotherapy followed by either chemoradiotherapy or bioradiotherapy for larynx preservation: the TREMPLIN randomized phase II study. J Clin Oncol Off J Am Soc Clin Oncol 31(7):853\u20139","DOI":"10.1200\/JCO.2012.42.3988"},{"key":"4550_CR24","doi-asserted-by":"crossref","unstructured":"Grandvuillemin A, Disson-Dautriche A, Miremont-Salam\u00e9 G, Fourrier-Reglat A, Sgro C (2013) R\u00e9seau des Centres R\u00e9gionaux de Pharmacovigilance Fran\u00e7ais. Cetuximab infusion reactions: French pharmacovigilance database analysis. J Oncol Pharm Pract Off Publ Int Soc Oncol Pharm Pract 19(2):130\u20137","DOI":"10.1177\/1078155212457965"},{"key":"4550_CR25","doi-asserted-by":"crossref","unstructured":"Mariotte D, Dupont B, Gervais R, Galais M-P, Laroche D, Tranchant A et al (2011) Anti-cetuximab IgE ELISA for identification of patients at a high risk of cetuximab-induced anaphylaxis. MAbs 3(4):396\u2013401","DOI":"10.4161\/mabs.3.4.16293"},{"key":"4550_CR26","doi-asserted-by":"crossref","unstructured":"Skladowski K, Law MG, Maciejewski B, Steel GG (1994) Planned and unplanned gaps in radiotherapy: the importance of gap position and gap duration. Radiother Oncol 30(2):109\u201320","DOI":"10.1016\/0167-8140(94)90039-6"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00405-017-4550-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-017-4550-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-017-4550-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T07:12:31Z","timestamp":1497337951000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00405-017-4550-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,5]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["4550"],"URL":"https:\/\/doi.org\/10.1007\/s00405-017-4550-7","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,5]]}}}