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Sabrina Overhagen, Andreas Bilstein, and Carina Kolot are employees at bitop AG (Dortmund, Germany). Uwe Sonnemann received sponsorship by Bitop AG to conduct the study. Ralph M\u00f6sges reports personal fees from ALK, Grants from ASIT biotech, personal fees from allergopharma, personal fees from Allergy Therapeutics, Grants and personal fees from Bencard, Grants from Leti, Grants, personal fees and non-financial support from Lofarma, non-financial support from Roxall, Grants and personal fees from Stallergenes, Grants from Optima, personal fees from Friulchem, personal fees from Hexal, personal fees from Servier, personal fees from Klosterfrau, non-financial support from Atmos, personal fees from Bayer, non-financial support from Bionorica, personal fees from FAES, personal fees from GSK, personal fees from MSD, personal fees from Johnson&Johnson, personal fees from Meda, personal fees and non-financial support from Novartis, non-financial support from Otonomy, personal fees from Stada, personal fees from UCB, non-financial support from Ferrero, Grants from BitopAG, Grants from Hulka, personal fees from Nuvo, Grants from Ursapharm, outside the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}