{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:44:02Z","timestamp":1778154242322,"version":"3.51.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T00:00:00Z","timestamp":1583280000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T00:00:00Z","timestamp":1583280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1007\/s00405-020-05873-4","type":"journal-article","created":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T07:04:00Z","timestamp":1583305440000},"page":"1779-1783","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical parameters predicting tonsillar malignancy"],"prefix":"10.1007","volume":"277","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9999-2174","authenticated-orcid":false,"given":"Avital","family":"Fellner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim","family":"Gavriel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Pitaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Limor","family":"Muallem Kalmovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,3,4]]},"reference":[{"issue":"3","key":"5873_CR1","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.critrevonc.2014.11.003","volume":"93","author":"AC Guimar\u00e3es","year":"2015","unstructured":"Guimar\u00e3es AC, de Carvalho GM, Correa CRS, Gusm\u00e3o RJ (2015) Association between unilateral tonsillar enlargement and lymphoma in children: a systematic review and meta-analysis. Crit Rev Oncol Hematol 93(3):304\u2013311","journal-title":"Crit Rev Oncol Hematol"},{"key":"5873_CR2","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.jpeds.2018.01.022","volume":"197","author":"EA Adil","year":"2018","unstructured":"Adil EA, Medina G, Cunningham MJ (2018) Pediatric tonsil cancer: a national and institutional perspective. J Pediatr 197:255\u2013261.e1","journal-title":"J Pediatr"},{"key":"5873_CR3","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ijporl.2018.04.027","volume":"110","author":"GH Jones","year":"2018","unstructured":"Jones GH, Burnside G, McPartland J, Markey A, Fallon M, De S (2018) Is tonsillectomy mandatory for asymmetric tonsils in children? A review of our diagnostic tonsillectomy practice and the literature. Int J PediatrOtorhinolaryngol 110:57\u201360","journal-title":"Int J PediatrOtorhinolaryngol"},{"issue":"4","key":"5873_CR4","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1177\/0194599813519972","volume":"150","author":"M Seshamani","year":"2014","unstructured":"Seshamani M, Vogtmann E, Gatwood J, Gibson TB, Scanlon D (2014) Prevalence of complications from adult tonsillectomy and impact on health care expenditures. Otolaryngol Head Neck Surg 150(4):574\u2013581","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"10","key":"5873_CR5","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1308\/147363503322520590","volume":"85","author":"D Lowe","year":"2003","unstructured":"Lowe D, van der Meulen J (2003) National prospective tonsillectomy audit. Bull R Coll Surg Engl 85(10):352\u2013353","journal-title":"Bull R Coll Surg Engl"},{"issue":"8","key":"5873_CR6","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1097\/00005537-200108000-00008","volume":"111","author":"LD KrishnaP","year":"2001","unstructured":"KrishnaP LD (2001) Post-tonsillectomy bleeding: a meta-analysis. Laryngoscope 111(8):1358\u20131361","journal-title":"Laryngoscope"},{"issue":"4","key":"5873_CR7","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1002\/lary.20852","volume":"120","author":"N Bhattacharyya","year":"2010","unstructured":"Bhattacharyya N (2010) Ambulatory pediatric otolaryngologic procedures in the United States: characteristics and perioperative safety. Laryngoscope 120(4):821\u2013825","journal-title":"Laryngoscope"},{"issue":"6","key":"5873_CR8","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1016\/j.otohns.2010.02.019","volume":"142","author":"TQ Gallagher","year":"2010","unstructured":"Gallagher TQ, Wilcox L, McGuire E, Derkay CS (2010) Analyzing factors associated with major complications after adenotonsillectomy in 4776 patients: comparing three tonsillectomy techniques. Otolaryngol Head Neck Surg 142(6):886\u2013892","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"6","key":"5873_CR9","first-page":"539","volume":"18","author":"MM Statham","year":"2010","unstructured":"Statham MM, Myer CM (2010) Complications of adenotonsillectomy. CurrOpinOtolaryngol Head Neck Surg 18(6):539\u2013543","journal-title":"CurrOpinOtolaryngol Head Neck Surg"},{"issue":"1","key":"5873_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.otohns.2006.02.036","volume":"135","author":"MT Brigger","year":"2006","unstructured":"Brigger MT, Brietzke SE (2006) Outpatient tonsillectomy in children: a systematic review. Otolaryngol Head Neck Surg 135(1):1\u20137","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"7","key":"5873_CR11","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1002\/lary.26972","volume":"128","author":"UC Megwalu","year":"2018","unstructured":"Megwalu UC, Sirjani D, Devine EE (2018) Oropharyngeal squamous cell carcinoma incidence and mortality trends in the United States, 1973\u20132013. Laryngoscope 128(7):1582\u20131588","journal-title":"Laryngoscope"},{"issue":"6","key":"5873_CR12","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1158\/1055-9965.EPI-15-0907","volume":"25","author":"AK Chaturvedi","year":"2016","unstructured":"Chaturvedi AK, Song H, Rosenberg PS et al (2016) Tonsillectomy and incidence of oropharyngeal cancers. Cancer Epidemiol Biomark Prev 25(6):944\u2013950","journal-title":"Cancer Epidemiol Biomark Prev"},{"issue":"11","key":"5873_CR13","doi-asserted-by":"publisher","first-page":"2438","DOI":"10.1002\/lary.25477","volume":"125","author":"MS Hwang","year":"2015","unstructured":"Hwang MS, Kaye KE, Waxman JA, Friedman M (2015) What is the best management of asymptomatic unilateral tonsillar enlargement? Laryngoscope 125(11):2438\u20132440","journal-title":"Laryngoscope"},{"issue":"6","key":"5873_CR14","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1016\/S0031-3955(16)36806-7","volume":"36","author":"L Brodsky","year":"1989","unstructured":"Brodsky L (1989) Modern assessment of tonsils and adenoids. Pediatr Clin N Am 36(6):1551\u20131569","journal-title":"Pediatr Clin N Am"},{"issue":"9","key":"5873_CR15","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1177\/000348949910800910","volume":"108","author":"RG Berkowitz","year":"1999","unstructured":"Berkowitz RG, Mahadevan M (1999) Unilateral tonsillar enlargement and tonsillar lymphoma in children. Ann Otol Rhinol Laryngol 108(9):876\u2013879","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"5","key":"5873_CR16","first-page":"367","volume":"97","author":"AC van Lierop","year":"2007","unstructured":"van Lierop AC, Prescott CJ, Fagan JJ, Sinclair-Smith CC (2007) Is diagnostic tonsillectomy indicated in all children with asymmetrically enlarged tonsils? S Afr Med J 97(5):367\u2013370","journal-title":"S Afr Med J"},{"issue":"1","key":"5873_CR17","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/S0165-5876(01)00633-4","volume":"63","author":"E Spinou","year":"2002","unstructured":"Spinou E, Kubba H, Konstantinidis I, Johnston A (2002) Tonsillectomy for biopsy in children with unilateral tonsillar enlargement. Int J PediatrOtorhinolaryngol 63(1):15\u201317","journal-title":"Int J PediatrOtorhinolaryngol"},{"issue":"7","key":"5873_CR18","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1001\/archotol.128.7.767","volume":"128","author":"EH Harley","year":"2002","unstructured":"Harley EH (2002) Asymmetric tonsil size in children. Arch Otolaryngol Head Neck Surg 128(7):767\u2013769","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"11","key":"5873_CR19","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1097\/00005537-200011000-00006","volume":"110","author":"MJ Syms","year":"2000","unstructured":"Syms MJ, Birkmire-Peters DP, Holtel MR (2000) Incidence of carcinoma in incidental tonsil asymmetry. Laryngoscope 110(11):1807\u20131810","journal-title":"Laryngoscope"},{"issue":"10","key":"5873_CR20","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1177\/014556130608501014","volume":"J85","author":"AF Oluwasanmi","year":"2006","unstructured":"Oluwasanmi AF, Wood SJ, Baldwin DL, Sipaul F (2006) Malignancy in asymmetrical but otherwise normal palatine tonsils. Ear Nose Throat J85(10):661\u2013663","journal-title":"Ear Nose Throat"},{"issue":"1","key":"5873_CR21","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.otohns.2004.02.004","volume":"131","author":"F Cinar","year":"2004","unstructured":"Cinar F (2004) Significance of asymptomatic tonsil asymmetry. Otolaryngol Head Neck Surg 131(1):101\u2013103","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"9","key":"5873_CR22","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1097\/MLG.0b013e318093ee4e","volume":"117","author":"DA Randall","year":"2007","unstructured":"Randall DA, Martin PJ, Thompson LDR (2007) Routine histologic examination is unnecessary for tonsillectomy or adenoidectomy. Laryngoscope 117(9):1600\u20131604","journal-title":"Laryngoscope"},{"issue":"7","key":"5873_CR23","first-page":"E21","volume":"120","author":"VS Sunkaraneni","year":"2006","unstructured":"Sunkaraneni VS, Jones SEM, Prasai A, Fish BM (2006) Is unilateral tonsillar enlargement alone an indication for tonsillectomy? J LaryngolOtol 120(7):E21","journal-title":"J LaryngolOtol"},{"issue":"5","key":"5873_CR24","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1002\/(SICI)1097-0347(199808)20:5<399::AID-HED7>3.0.CO;2-T","volume":"20","author":"MM Beaty","year":"1998","unstructured":"Beaty MM, Funk GF, Karnell LH et al (1998) Risk factors for malignancy in adult tonsils. Head Neck 20(5):399\u2013403","journal-title":"Head Neck"},{"issue":"10","key":"5873_CR25","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1111\/j.1365-4632.2009.04432.x","volume":"49","author":"PR Cohen","year":"2010","unstructured":"Cohen PR, Tschen JA (2010) Tonsillar actinomycosis mimicking a tonsillolith: colonization of the palantine tonsil presenting as a foul-smelling, removable, unilateral, giant tonsillar concretion. Int J Dermatol 49(10):1165\u20131168","journal-title":"Int J Dermatol"},{"issue":"12","key":"5873_CR26","doi-asserted-by":"publisher","first-page":"1883","DOI":"10.1016\/j.ijporl.2007.08.021","volume":"71","author":"AC van Lierop","year":"2007","unstructured":"van Lierop AC, Prescott CJ, Sinclair-Smith CC (2007) An investigation of the significance of actinomycosis in tonsil disease. Int J PediatrOtorhinolaryngol 71(12):1883\u20131888","journal-title":"Int J PediatrOtorhinolaryngol"},{"issue":"9","key":"5873_CR27","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1080\/00016480600590604","volume":"126","author":"K Takasaki","year":"2006","unstructured":"Takasaki K, Kitaoka K, Kaieda S, Hayashi T, Abe K, Takahashi H (2006) A case of actinomycosis causing unilateral tonsillar hypertrophy. Acta Oto-Laryngologica 126(9):1001\u20131004","journal-title":"Acta Oto-Laryngologica"},{"issue":"1","key":"5873_CR28","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0165-5876(01)00647-4","volume":"63","author":"SPS Yadav","year":"2002","unstructured":"Yadav SPS, Chanda R, Gathwala G, Yadav RK (2002) Actinomycosis of tonsil masquerading as tumour in a 12-year old child. Int J Pediatr Otorhinolaryngol 63(1):73\u201375","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"1","key":"5873_CR29","doi-asserted-by":"publisher","first-page":"31","DOI":"10.14712\/18059694.2016.60","volume":"53","author":"D Rasi\u0107","year":"2010","unstructured":"Rasi\u0107 D, Peri\u0107 A, Vukomanovi\u0107-Durdevi\u0107 B (2010) A case of an unilateral tonsillar hypertrophy caused by actinomycosis. Acta Med (Hradec Kralove) 53(1):31\u201333","journal-title":"Acta Med (Hradec Kralove)"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-05873-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00405-020-05873-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-05873-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T00:38:28Z","timestamp":1614818308000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00405-020-05873-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,4]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["5873"],"URL":"https:\/\/doi.org\/10.1007\/s00405-020-05873-4","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,4]]},"assertion":[{"value":"28 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the Institutional Review Board of Shamir Medical Center (#0185\u201317-ASF). As this is a retrospective study with no intervention, an informed consent waiver was granted by the Helsinki Institutional Review Board.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}