{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:18:50Z","timestamp":1791883130836,"version":"4.3.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The purpose of this study is to assess the general course of acoustic, patient rated, and clinician-rated voice outcomes from pre- up to 12\u00a0months post total laryngectomy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patients admitted to a total laryngectomy in five participating hospitals in Australia and The Netherlands were included. Assessments took place at pre-, 3\u00a0months, 6\u00a0months, and 12\u00a0months post-surgery. Voice outcomes are evaluated with the Acoustic Voice Quality Index (AVQI), perceptual scales, and patient-reported outcome measures including VHI-10 and EQ-5D-5L. Statistical analyses include descriptive statistics, <jats:italic>t<\/jats:italic> tests (pre- to 6\u00a0months post-surgery), Linear Mixed Effect models.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The study included 43 participants. A significant worsening of <jats:italic>AVQI<\/jats:italic> is seen from pre- to post-surgery evaluated with <jats:italic>t<\/jats:italic> test (p\u2009&lt;\u20090.001). The Linear Mixed Effect model confirmed <jats:italic>Time<\/jats:italic> as a significant factor in predicting <jats:italic>AVQI<\/jats:italic> score (<jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001), as well as <jats:italic>perceptual rated voice quality<\/jats:italic> by the clinician (<jats:italic>p<\/jats:italic>\u2009=\u20090.015) and <jats:italic>patient<\/jats:italic>-<jats:italic>reported perceptual rated voice quality<\/jats:italic> (<jats:italic>p<\/jats:italic>\u2009=\u20090.002). No statistical significance was found in <jats:italic>VHI<\/jats:italic>-<jats:italic>10<\/jats:italic> scores over time.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Successful TE-speech was achieved in most participants, some had to rely on augmentative alternative communication methods. Patient-reported outcomes indicate acceptance of the condition and sufficient coping in the long term. However, acoustic rated voice quality is abnormal at all post-surgery time-points. <jats:italic>AVQI<\/jats:italic> proved to be a useful instrument to evaluate TE-speech. There is a need for validation and determination of cut-off values for <jats:italic>VHI<\/jats:italic>-<jats:italic>10<\/jats:italic> and <jats:italic>AVQI<\/jats:italic> for use in TE-speech.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-020-06216-z","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T18:09:17Z","timestamp":1595354957000},"page":"1209-1222","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Multidimensional evaluation of voice outcomes following total laryngectomy: a prospective multicenter cohort study"],"prefix":"10.1007","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9288-5402","authenticated-orcid":false,"given":"Klaske E.","family":"van Sluis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob J. J. H.","family":"van Son","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisette","family":"van der Molen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony John","family":"MCGuinness","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten E.","family":"Palme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Novakovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Natsis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Charters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Dirven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiel W. M.","family":"van den Brekel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"issue":"4","key":"6216_CR1","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1007\/s11136-018-2033-y","volume":"28","author":"G Sharpe","year":"2019","unstructured":"Sharpe G, Costa VC, Doub\u00e9 W, Sita J, McCarthy C, Carding P (2019) Communication changes with laryngectomy and impact on quality of life: a review. Qual Life Res 28(4):863\u2013877","journal-title":"Qual Life Res"},{"issue":"1","key":"6216_CR2","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s00405-017-4790-6","volume":"275","author":"KE van Sluis","year":"2018","unstructured":"van Sluis KE, van der Molen L, van Son RJ, Hilgers FJ, Bhairosing PA, van den Brekel MW (2018) Objective and subjective voice outcomes after total laryngectomy: a systematic review. Eur Arch Otorhinolaryngol 275(1):11\u201326","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"10","key":"6216_CR3","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/S1726-4901(08)70030-3","volume":"70","author":"S Singer","year":"2007","unstructured":"Singer S, Merbach M, Dietz A, Schwarz R (2007) Psychosocial determinants of successful voice rehabilitation after laryngectomy. J Chin Med Assoc 70(10):407\u2013423","journal-title":"J Chin Med Assoc"},{"issue":"3","key":"6216_CR4","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/MOO.0000000000000358","volume":"25","author":"A Hurren","year":"2017","unstructured":"Hurren A, Miller N (2017) Voice outcomes post total laryngectomy. Curr Opin Otolaryngol Head Neck Surg 25(3):205\u2013210","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"7","key":"6216_CR5","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1177\/0003489416636131","volume":"125","author":"B Barsties","year":"2016","unstructured":"Barsties B, Maryn Y (2016) External validation of the Acoustic Voice Quality Index version 03.01 with extended representativity. Ann Otol Rhinol Laryngol 125(7):571\u2013583","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"6","key":"6216_CR6","first-page":"1609","volume":"271","author":"Y Maryn","year":"2014","unstructured":"Maryn Y, De Bodt M, Barsties B, Roy N (2014) The value of the Acoustic Voice Quality Index as a measure of dysphonia severity in subjects speaking different languages. Eur Arch Otorhinolaryngol 271(6):1609\u20131619","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"3","key":"6216_CR7","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1002\/hed.23305","volume":"36","author":"S Singer","year":"2014","unstructured":"Singer S, Danker H, Guntinas-Lichius O, Oeken J, Pabst F, Schock J, Vogel HJ, Meister EF, Wulke C, Dietz A (2014) Quality of life before and after total laryngectomy: results of a multicenter prospective cohort study. Head Neck 36(3):359\u2013368","journal-title":"Head Neck"},{"issue":"1","key":"6216_CR8","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1002\/1097-0347(200101)23:1<16::AID-HED3>3.0.CO;2-4","volume":"23","author":"E Armstrong","year":"2001","unstructured":"Armstrong E, Isman K, Dooley P, Brine D, Riley N, Dentice R, King S, Khanbhai F (2001) An investigation into the quality of life of individuals after laryngectomy. Head Neck 23(1):16\u201324","journal-title":"Head Neck"},{"issue":"6","key":"6216_CR9","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1001\/archotol.133.6.526","volume":"133","author":"TD Woodard","year":"2007","unstructured":"Woodard TD, Oplatek A, Petruzzelli GJ (2007) Life after total laryngectomy: a measure of long-term survival, function, and quality of life. Archiv Otolaryngol Head Neck Surg 133(6):526\u2013532. https:\/\/doi.org\/10.1001\/archotol.133.6.526","journal-title":"Archiv Otolaryngol Head Neck Surg"},{"issue":"4","key":"6216_CR10","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1002\/(SICI)1097-0347(199907)21:4<319::AID-HED5>3.0.CO;2-H","volume":"21","author":"FW Deleyiannis","year":"1999","unstructured":"Deleyiannis FW, Weymuller EA Jr, Coltrera MD, Futran N (1999) Quality of life after laryngectomy: are functional disabilities important? Head Neck 21(4):319\u2013324","journal-title":"Head Neck"},{"issue":"10","key":"6216_CR11","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1097\/00005537-199810000-00027","volume":"108","author":"C Finizia","year":"1998","unstructured":"Finizia C, Hammerlid E, Westin T, Lindstrom J (1998) Quality of life and voice in patients with laryngeal carcinoma: a posttreatment comparison of laryngectomy (salvage surgery) versus radiotherapy. Laryngoscope 108(10):1566\u20131573. https:\/\/doi.org\/10.1097\/00005537-199810000-00027","journal-title":"Laryngoscope"},{"issue":"1","key":"6216_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/(SICI)1097-0347(199601\/02)18:1<1::AID-HED1>3.0.CO;2-7","volume":"18","author":"MA List","year":"1996","unstructured":"List MA, Ritter-Sterr CA, Baker TM, Colangelo LA, Matz G, Pauloski BR, Logemann JA (1996) Longitudinal assessment of quality of life in laryngeal cancer patients. Head Neck 18(1):1\u201310","journal-title":"Head Neck"},{"issue":"8","key":"6216_CR13","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1097\/00005537-200108000-00022","volume":"111","author":"K Bjordal","year":"2001","unstructured":"Bjordal K, Ahlner-Elmqvist M, Hammerlid E, Boysen M, Evensen JF, Bi\u00f6rklund A, Jannert M, Westin T, Kaasa S (2001) A prospective study of quality of life in head and neck cancer patients. Part II: Longitudinal data. Laryngoscope 111(8):1440\u20131452","journal-title":"Laryngoscope"},{"issue":"2","key":"6216_CR14","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1002\/cncr.20010","volume":"100","author":"FM Fang","year":"2004","unstructured":"Fang FM, Liu YT, Tang Y, Wang CJ, Ko SF (2004) Quality of life as a survival predictor for patients with advanced head and neck carcinoma treated with radiotherapy. Cancer 100(2):425\u2013432","journal-title":"Cancer"},{"issue":"5","key":"6216_CR15","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1097\/00005537-199805000-00023","volume":"108","author":"E Hammerlid","year":"1998","unstructured":"Hammerlid E, Mercke C, Sullivan M, Westin T (1998) A prospective quality of life study of patients with laryngeal carcinoma by tumor stage and different radiation therapy schedules. Laryngoscope 108(5):747\u2013759","journal-title":"Laryngoscope"},{"issue":"5","key":"6216_CR16","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/S0194-5998(00)70208-7","volume":"122","author":"MR Arias","year":"2000","unstructured":"Arias MR, Ram\u00f3n JL, Campos M, Cervantes JJ (2000) Acoustic analysis of the voice in phonatory fistuloplasty after total laryngectomy. Otolaryngol Head Neck Surg 122(5):743\u2013747","journal-title":"Otolaryngol Head Neck Surg"},{"key":"6216_CR17","doi-asserted-by":"crossref","unstructured":"Bellandese MH, Lerman JW, Gilbert HR (2001) An acoustic analysis of excellent female esophageal, tracheoesophageal, and laryngeal speakers. J Speech Lang Hear Res","DOI":"10.1044\/1092-4388(2001\/102)"},{"issue":"2","key":"6216_CR18","first-page":"111","volume":"36","author":"L \u0160iri\u0107","year":"2012","unstructured":"\u0160iri\u0107 L, \u0160o\u0161 D, Rosso M, Stevanovi\u0107 S (2012) Objective assessment of tracheoesophageal and esophageal speech using acoustic analysis of voice. Collegium Antropol 36(2):111\u2013114","journal-title":"Collegium Antropol"},{"issue":"2","key":"6216_CR19","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1055\/s-2004-826068","volume":"84","author":"M Schuster","year":"2005","unstructured":"Schuster M, Toy H, Lohscheller J, Eysholdt U, Rosanowski F (2005) Quality of life and voice handicap of laryngectomees using tracheoesophageal substitute voice. Laryngorhinootologie 84(2):101\u2013107","journal-title":"Laryngorhinootologie"},{"issue":"2","key":"6216_CR20","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1159\/000208807","volume":"61","author":"E Lundstr\u00f6m","year":"2009","unstructured":"Lundstr\u00f6m E, Hammarberg B, Munck-Wikland E (2009) Voice handicap and health-related quality of life in laryngectomees: assessments with the use of VHI and EORTC questionnaires. Folia Phoniatrica et Logopaedica 61(2):83\u201392","journal-title":"Folia Phoniatrica et Logopaedica"},{"issue":"5","key":"6216_CR21","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s00405-005-1033-z","volume":"263","author":"M Moerman","year":"2006","unstructured":"Moerman M, Martens J-P, Crevier-Buchman L, de Haan E, Grand S, Tessier C, Woisard V, Dejonckere P (2006) The INFVo perceptual rating scale for substitution voicing: development and reliability. Eur Arch Otorhinolaryngol 263(5):435\u2013439","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"6216_CR22","volume-title":"EQ-5D-5L user guide: basic information on how to use the EQ-5D-5L instrument","author":"M van Reenen","year":"2015","unstructured":"van Reenen M, Janssen B (2015) EQ-5D-5L user guide: basic information on how to use the EQ-5D-5L instrument. EuroQol Research Foundation, Rotterdam"},{"issue":"4","key":"6216_CR23","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.jval.2016.01.003","volume":"19","author":"MM Versteegh","year":"2016","unstructured":"Versteegh MM, Vermeulen KM, Evers SM, de Wit GA, Prenger R, Stolk EA (2016) Dutch tariff for the five-level version of EQ-5D. Value Health 19(4):343\u2013352","journal-title":"Value Health"},{"issue":"3","key":"6216_CR24","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1044\/1058-0360.0603.66","volume":"6","author":"BH Jacobson","year":"1997","unstructured":"Jacobson BH, Johnson A, Grywalski C, Silbergleit A, Jacobson G, Benninger MS, Newman CW (1997) The voice handicap index (VHI) development and validation. Am J Speech Lang Pathol 6(3):66\u201370","journal-title":"Am J Speech Lang Pathol"},{"issue":"9","key":"6216_CR25","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1097\/00005537-200409000-00009","volume":"114","author":"CA Rosen","year":"2004","unstructured":"Rosen CA, Lee AS, Osborne J, Zullo T, Murry T (2004) Development and validation of the voice handicap index-10. Laryngoscope 114(9):1549\u20131556. https:\/\/doi.org\/10.1097\/00005537-200409000-00009","journal-title":"Laryngoscope"},{"issue":"4","key":"6216_CR26","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/j.jvoice.2011.04.006","volume":"26","author":"RE Arffa","year":"2012","unstructured":"Arffa RE, Krishna P, Gartner-Schmidt J, Rosen CA (2012) Normative values for the Voice Handicap Index-10. J Voice 26(4):462\u2013465. https:\/\/doi.org\/10.1016\/j.jvoice.2011.04.006","journal-title":"J Voice"},{"key":"6216_CR27","unstructured":"Boersma PPG, Weenink DJM (1996) Praat: doing phonetics by computer: version 3.4. Instituut voor Fonetische Wetenschappen"},{"key":"6216_CR28","volume-title":"IBM SPSS Statistics for Windows","author":"IBM Corp","year":"2013","unstructured":"IBM Corp (2013) IBM SPSS Statistics for Windows, 22.0th edn. IBM Corp, Armonk","edition":"22.0"},{"key":"6216_CR29","volume-title":"R: a language and environment for statistical computing","author":"Team RC","year":"2013","unstructured":"Team RC (2013) R: a language and environment for statistical computing. Team RC, Vienna"},{"key":"6216_CR30","doi-asserted-by":"crossref","unstructured":"Almonacid CIF, Ramos AJ, Rodr\u00edguez-Borrego M-A (2016) Level of anxiety versus self-care in the preoperative and postoperative periods of total laryngectomy patients. Revista latino-americana de enfermagem 24","DOI":"10.1590\/1518-8345.0743.2707"},{"issue":"2","key":"6216_CR31","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/hed.21702","volume":"34","author":"S Singer","year":"2012","unstructured":"Singer S, Krau\u00df O, Keszte J, Siegl G, Papsdorf K, Severi E, Hauss J, Briest S, Dietz A, Br\u00e4hler E (2012) Predictors of emotional distress in patients with head and neck cancer. Head Neck 34(2):180\u2013187","journal-title":"Head Neck"},{"issue":"10","key":"6216_CR32","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1007\/s00405-010-1316-x","volume":"267","author":"I Jacobi","year":"2010","unstructured":"Jacobi I, van der Molen L, Huiskens H, Van Rossum MA, Hilgers FJ (2010) Voice and speech outcomes of chemoradiation for advanced head and neck cancer: a systematic review. Eur Arch Otorhinolaryngol 267(10):1495\u20131505","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"S1","key":"6216_CR33","doi-asserted-by":"publisher","first-page":"E1955","DOI":"10.1002\/hed.24353","volume":"38","author":"TL Eadie","year":"2016","unstructured":"Eadie TL, Otero D, Cox S, Johnson J, Baylor CR, Yorkston KM, Doyle P (2016) The relationship between communicative participation and postlaryngectomy speech outcomes. Head Neck 38(S1):E1955\u2013E1961","journal-title":"Head Neck"},{"issue":"8","key":"6216_CR34","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/s00405-003-0683-y","volume":"261","author":"M Moerman","year":"2004","unstructured":"Moerman M, Martens J-P, Dejonckere P (2004) Application of the Voice Handicap Index in 45 patients with substitution voicing after total laryngectomy. Eur Arch Otorhinolaryngol 261(8):423\u2013428","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"6216_CR35","doi-asserted-by":"crossref","unstructured":"van Sluis KE, van den Brekel MW, Hilgers FJ, van Son RJ (2016) Long-term stability of tracheoesophageal voices. In: Paper presented at the interspeech. San Fransisco","DOI":"10.21437\/Interspeech.2016-114"},{"issue":"3","key":"6216_CR36","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.anl.2014.11.001","volume":"42","author":"B Barsties","year":"2015","unstructured":"Barsties B, De Bodt M (2015) Assessment of voice quality: current state-of-the-art. Auris Nasus Larynx 42(3):183\u2013188","journal-title":"Auris Nasus Larynx"},{"issue":"11","key":"6216_CR37","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1200\/JCO.2017.75.7385","volume":"36","author":"AA Forastiere","year":"2018","unstructured":"Forastiere AA, Ismaila N, Lewin JS, Nathan CA, Adelstein DJ, Eisbruch A, Fass G, Fisher SG, Laurie SA, Le Q-T (2018) Use of larynx-preservation strategies in the treatment of laryngeal cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 36(11):1143\u20131169","journal-title":"J Clin Oncol"},{"key":"6216_CR38","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.oraloncology.2018.11.022","volume":"88","author":"DA Silverman","year":"2019","unstructured":"Silverman DA, Puram SV, Rocco JW, Old MO, Kang SY (2019) Salvage laryngectomy following organ-preservation therapy\u2014an evidence-based review. Oral Oncol 88:137\u2013144","journal-title":"Oral Oncol"},{"issue":"12","key":"6216_CR39","doi-asserted-by":"publisher","first-page":"2715","DOI":"10.1002\/lary.25404","volume":"125","author":"DG Deschler","year":"2015","unstructured":"Deschler DG, Herr MW, Kmiecik JR, Sethi R, Bunting G (2015) Tracheoesophageal voice after total laryngopharyngectomy reconstruction: Jejunum versus radial forearm free flap. Laryngoscope 125(12):2715\u20132721","journal-title":"Laryngoscope"},{"issue":"9","key":"6216_CR40","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.1007\/s00405-015-3777-4","volume":"273","author":"I Jacobi","year":"2016","unstructured":"Jacobi I, Timmermans AJ, Hilgers FJ, van den Brekel MW (2016) Voice quality and surgical detail in post-laryngectomy tracheoesophageal speakers. Eur Archiv Otorhinol 273(9):2669\u20132679. https:\/\/doi.org\/10.1007\/s00405-015-3777-4","journal-title":"Eur Archiv Otorhinol"},{"issue":"7","key":"6216_CR41","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.1007\/s11136-012-0300-x","volume":"22","author":"L McClimans","year":"2013","unstructured":"McClimans L, Bickenbach J, Westerman M, Carlson L, Wasserman D, Schwartz C (2013) Philosophical perspectives on response shift. Qual Life Res 22(7):1871\u20131878","journal-title":"Qual Life Res"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06216-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-020-06216-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06216-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T23:38:38Z","timestamp":1626824318000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-020-06216-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,21]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["6216"],"URL":"https:\/\/doi.org\/10.1007\/s00405-020-06216-z","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,21]]},"assertion":[{"value":"4 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors have no other funding, financial relationships, or conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"Informed consent was obtained from all participants included in the study. For the Netherlands Cancer Institute, the study is registered under number IRBd18005\/N18VOQ, for the Australian sites registered under Protocol no X16-0287 & HREC\/16\/RPAH\/367.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics"}}]}}