{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:41:39Z","timestamp":1789756899272,"version":"4.0.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T00:00:00Z","timestamp":1596844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T00:00:00Z","timestamp":1596844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s00405-020-06271-6","type":"journal-article","created":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T07:02:37Z","timestamp":1596870157000},"page":"1821-1827","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["MRI of endolymphatic hydrops in patients with intralabyrinthine schwannomas: a case-controlled study using non-enhanced T2\u2013weighted images at 3\u00a0T"],"prefix":"10.1007","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0608-2353","authenticated-orcid":false,"given":"A\u00efna","family":"Venkatasamy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Bretz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Karol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Karch-Georges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Charpiot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Veillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,8]]},"reference":[{"issue":"5","key":"6271_CR1","doi-asserted-by":"publisher","first-page":"898","DOI":"10.3174\/ajnr.A1026","volume":"29","author":"A Tieleman","year":"2008","unstructured":"Tieleman A, Casselman JW, Somers T, Delanote J, Kuhweide R, Ghekiere J, Offeciers EF (2008) Imaging of intralabyrinthine schwannomas: a retrospective study of 52 cases with emphasis on lesion growth. Am J Neuroradiol 29(5):898\u2013905","journal-title":"Am J Neuroradiol"},{"issue":"2","key":"6271_CR2","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1097\/00129492-200403000-00014","volume":"25","author":"RJ Kennedy","year":"2004","unstructured":"Kennedy RJ, Shelton C, Salzman KL, Davidson HC, Harnsberger HR (2004) Intralabyrinthine schwannomas: diagnosis, management, and a new classification system. Otol Neurotol 25(2):160\u2013167","journal-title":"Otol Neurotol"},{"issue":"1","key":"6271_CR3","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1159\/000108109","volume":"13","author":"F Dispenza","year":"2008","unstructured":"Dispenza F, De Stefano A, Flanagan S, Romano G, Sanna M (2008) Decision making for solitary vestibular schwannoma and contralateral Meniere\u2019s disease. Audiol Neurotol 13(1):53\u201357","journal-title":"Audiol Neurotol"},{"issue":"2","key":"6271_CR4","first-page":"128","volume":"21","author":"M Ralli","year":"2017","unstructured":"Ralli M, Greco A, Altissimi G, Turchetta R, Longo L, D\u00e2 Aguanno V, de Vincentiis M (2017) Vestibular schwannoma and ipsilateral endolymphatic hydrops: an unusual association. Int Tinnitus J 21(2):128","journal-title":"Int Tinnitus J"},{"issue":"543","key":"6271_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1080\/000164800453838","volume":"120","author":"E Kentala","year":"2000","unstructured":"Kentala E (2000) Vestibular schwannoma mimicking Meniere's disease. Acta Otolaryngol 120(543):17\u201319","journal-title":"Acta Otolaryngol"},{"issue":"6","key":"6271_CR6","first-page":"1033","volume":"2015","author":"C Jerin","year":"2015","unstructured":"Jerin C, Krause E, Ertl-Wagner B (2015) Endolymphatic hydrops in a patient with a small vestibular schwannoma suggests a peripheral origin of vertigo. Austin J Radiol 2015(6):1033","journal-title":"Austin J Radiol"},{"issue":"3","key":"6271_CR7","doi-asserted-by":"publisher","first-page":"338","DOI":"10.3109\/00016480903143986","volume":"130","author":"T Nakashima","year":"2010","unstructured":"Nakashima T, Naganawa S, Teranishi M, Tagaya M, Nakata S, Sone M, Nishio N (2010) Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with M\u00e9ni\u00e8re's disease. Acta Otolaryngol 130(3):338\u2013343","journal-title":"Acta Otolaryngol"},{"key":"6271_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00405-019-05395-8","volume":"276","author":"A Karch-Georges","year":"2019","unstructured":"Karch-Georges A, Veillon F, Vuong H, Rohmer D, Karol A, Charpiot A, Venkatasamy A (2019) MRI of endolymphatic hydrops in patients with vestibular schwannomas: a case-controlled study using non-enhanced T2-weighted images at 3 Teslas. Eur Archiv Oto-Rhino-Laryngol 276:1\u20139","journal-title":"Eur Archiv Oto-Rhino-Laryngol"},{"issue":"12","key":"6271_CR9","doi-asserted-by":"publisher","first-page":"4113","DOI":"10.1007\/s00405-017-4756-8","volume":"274","author":"F Simon","year":"2017","unstructured":"Simon F, Guichard JP, Kania R, Franc J, Herman P, Hautefort C (2017) Saccular measurements in routine MRI can predict hydrops in Meni\u00e8re\u2019s disease. Eur Arch Otorhinolaryngol 274(12):4113\u20134120","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"9","key":"6271_CR10","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1097\/MAO.0000000000000415","volume":"35","author":"X Dubernard","year":"2014","unstructured":"Dubernard X, Somers T, Veros K, Vincent C, Franco-Vidal V, Deguine O, Mondain M (2014) Clinical presentation of intralabyrinthine schwannomas: a multicenter study of 110 cases. Otol Neurotol 35(9):1641\u20131649","journal-title":"Otol Neurotol"},{"issue":"5","key":"6271_CR11","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1007\/s00330-008-0854-8","volume":"18","author":"S Naganawa","year":"2008","unstructured":"Naganawa S, Satake H, Kawamura M, Fukatsu H, Sone M, Nakashima T (2008) Separate visualization of endolymphatic space, perilymphatic space and bone by a single pulse sequence; 3D-inversion recovery imaging utilizing real reconstruction after intratympanic Gd-DTPA administration at 3 Tesla. Eur Radiol 18(5):920\u2013924","journal-title":"Eur Radiol"},{"issue":"2","key":"6271_CR12","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.rxeng.2017.02.001","volume":"59","author":"MT Gomez","year":"2017","unstructured":"Gomez MT, Duro DL, Alvarez BB, Garcia-Berrocal JR (2017) Diagnosis of endolymphatic hydrops by means of 3 T magnetic resonance imaging after intratympanic administration of gadolinium. Radiolog\u00eda (English Edition) 59(2):159\u2013165","journal-title":"Radiolog\u00eda (English Edition)"},{"issue":"8","key":"6271_CR13","doi-asserted-by":"publisher","first-page":"3138","DOI":"10.1007\/s00330-016-4701-z","volume":"27","author":"A Atty\u00e9","year":"2017","unstructured":"Atty\u00e9 A, Eliezer M, Boudiaf N, Tropres I, Chechin D, Schmerber S, Krainik A (2017) MRI of endolymphatic hydrops in patients with Meniere\u2019s disease: a case-controlled study with a simplified classification based on saccular morphology. Eur Radiol 27(8):3138\u20133146","journal-title":"Eur Radiol"},{"issue":"1","key":"6271_CR14","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.clinimag.2014.09.014","volume":"39","author":"AR Sepahdari","year":"2015","unstructured":"Sepahdari AR, Ishiyama G, Vorasubin N, Peng KA, Linetsky M, Ishiyama A (2015) Delayed intravenous contrast-enhanced 3D FLAIR MRI in Meniere\u2019s disease: correlation of quantitative measures of endolymphatic hydrops with hearing. Clin Imaging 39(1):26\u201331","journal-title":"Clin Imaging"},{"key":"6271_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00330-017-5260-7","volume":"28","author":"A Atty\u00e9","year":"2018","unstructured":"Atty\u00e9 A, Eliezer M, Medici M, Tropres I, Dumas G, Krainik A, Schmerber S (2018) In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere\u2019s disease symptoms. Eur Radiol 28:1\u20137","journal-title":"Eur Radiol"},{"issue":"5","key":"6271_CR16","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.diii.2019.01.006","volume":"100","author":"M Eliezer","year":"2019","unstructured":"Eliezer M, Poillon G, Maquet C, Gillibert A, Horion J, Marie JP, Atty\u00e9 A (2019) Sensorineural hearing loss in patients with vestibular schwannoma correlates with the presence of utricular hydrops as diagnosed on heavily T2-weighted MRI. Diagn Interv Imaging 100(5):259\u2013268","journal-title":"Diagn Interv Imaging"},{"key":"6271_CR17","first-page":"1","volume":"00","author":"W Zhang","year":"2020","unstructured":"Zhang W, Hui L, Zhang B, Ren L, Zhu J, Wang F, Li S (2020) The correlation between endolymphatic hydrops and clinical features of meniere disease. Laryngoscope 00:1\u20137","journal-title":"Laryngoscope"},{"issue":"5","key":"6271_CR18","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/j.otc.2010.05.007","volume":"43","author":"AN Salt","year":"2010","unstructured":"Salt AN, Plontke SK (2010) Endolymphatic hydrops: pathophysiology and experimental models. Otolaryngol Clin North Am 43(5):971\u2013983","journal-title":"Otolaryngol Clin North Am"},{"issue":"4","key":"6271_CR19","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1177\/0194599818756829","volume":"158","author":"MH Asmar","year":"2018","unstructured":"Asmar MH, Gaboury L, Saliba I (2018) M\u00e9ni\u00e8re\u2019s disease pathophysiology: endolymphatic sac immunohistochemical study of aquaporin-2, V2R vasopressin receptor, NKCC2, and TRPV4. Otolaryngol Head Neck Surg 158(4):721\u2013728","journal-title":"Otolaryngol Head Neck Surg"},{"key":"6271_CR20","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1001\/archotol.1966.00760030397003","volume":"84","author":"H Silverstein","year":"1966","unstructured":"Silverstein H, Schuknecht HF (1966) Biochemical studies of inner ear fluid in man. Arch Otolaryngol 84:395\u2013402","journal-title":"Arch Otolaryngol"},{"issue":"12","key":"6271_CR21","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1007\/s00234-010-0834-y","volume":"53","author":"S Naganawa","year":"2011","unstructured":"Naganawa S, Kawai H, Sone M, Nakashima T, Ikeda M (2011) Endolympathic hydrops in patients with vestibular schwannoma: visualization by non-contrast-enhanced 3D FLAIR. Neuroradiology 53(12):1009\u20131015","journal-title":"Neuroradiology"},{"issue":"4","key":"6271_CR22","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1007\/s00330-009-1626-9","volume":"20","author":"IH Lee","year":"2010","unstructured":"Lee IH, Kim HJ, Chung WH, Kim E, Moon JW, Kim ST, Byun HS (2010) Signal intensity change of the labyrinth in patients with surgically confirmed or radiologically diagnosed vestibular schwannoma on isotropic 3D fluid-attenuated inversion recovery MR imaging at 3 T. Eur Radiol 20(4):949\u2013957","journal-title":"Eur Radiol"},{"issue":"1","key":"6271_CR23","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s41747-017-0012-7","volume":"1","author":"A Venkatasamy","year":"2017","unstructured":"Venkatasamy A, Le Foll D, Karol A, Lhermitte B, Charpiot A, Debry C, Veillon F (2017) Differentiation of vestibular schwannomas from meningiomas of the internal auditory canal using perilymphatic signal evaluation on T2-weighted gradient-echo fast imaging employing steady state acquisition at 3T. Eur Radiol Exp 1(1):8","journal-title":"Eur Radiol Exp"},{"key":"6271_CR24","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1016\/j.crad.2016.06.033","volume":"71","author":"JK Dixon","year":"2016","unstructured":"Dixon JK, Loney E (2016) Hearing loss in vestibular schwannoma: size isn't everything. Clin Radiol 71:S4","journal-title":"Clin Radiol"},{"issue":"9","key":"6271_CR25","doi-asserted-by":"publisher","first-page":"e46132","DOI":"10.1371\/journal.pone.0046132","volume":"7","author":"AR Asthagiri","year":"2012","unstructured":"Asthagiri AR, Vasquez RA, Butman JA, Wu T, Morgan K, Brewer CC, Lonser RR (2012) Mechanisms of hearing loss in neurofibromatosis type 2. PLoS ONE 7(9):e46132","journal-title":"PLoS ONE"},{"issue":"4","key":"6271_CR26","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1097\/MAO.0b013e31828048ec","volume":"34","author":"S Dilwali","year":"2013","unstructured":"Dilwali S, Lysaght A, Roberts D, Barker FG, McKenna MJ, Stankovic KM (2013) Sporadic vestibular schwannomas associated with good hearing secrete higher levels of fibroblast growth factor 2 than those associated with poor hearing irrespective of tumor size. Otol Neurotol 34(4):748\u2013754","journal-title":"Otol Neurotol"},{"issue":"2","key":"6271_CR27","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000275574","volume":"44","author":"J Thomsen","year":"1982","unstructured":"Thomsen J, Saxtrup O, Tos M (1982) Quantitated determination of proteins in perilymph in patients with acoustic neuromas. ORL J Otorhinolaryngol Relat Spec 44(2):61\u201365","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"issue":"3","key":"6271_CR28","first-page":"193","volume":"2","author":"AF O\u2019Connor","year":"1981","unstructured":"O\u2019Connor AF, France MW, Morrison AW (1981) Perilymph total protein levels associated with cerebellopontine angle lesions. Am J Otol 2(3):193\u2013195","journal-title":"Am J Otol"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06271-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-020-06271-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06271-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,7]],"date-time":"2021-08-07T23:19:34Z","timestamp":1628378374000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-020-06271-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,8]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["6271"],"URL":"https:\/\/doi.org\/10.1007\/s00405-020-06271-6","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,8]]},"assertion":[{"value":"3 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}