{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:58:22Z","timestamp":1788544702196,"version":"build-2803163510"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1007\/s00405-020-06294-z","type":"journal-article","created":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T12:03:35Z","timestamp":1598270615000},"page":"2193-2201","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["The role of adjuvant systemic steroids in the management of periorbital cellulitis secondary to sinusitis: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5958-2322","authenticated-orcid":false,"given":"Sridhayan","family":"Mahalingam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Luke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyotsna","family":"Pundir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Pundir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,24]]},"reference":[{"key":"6294_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.ijporl.2018.05.006","volume":"110","author":"SJ Wong","year":"2018","unstructured":"Wong SJ, Levi J (2018) Management of pediatric orbital cellulitis: a systematic review. Int J Pediatr Otorhinolaryngol 110:123\u2013129","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"10","key":"6294_CR2","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1097\/INF.0000000000002414","volume":"38","author":"A Trivi\u0107","year":"2019","unstructured":"Trivi\u0107 A, Cevik M, Foli\u0107 M, Krejovic-Trivi\u0107 S, Rubino S, Mici\u0107 J et al (2019) Management of orbital complications of acute rhinosinusitis in pediatric patients. Pediatr Infect Dis J 38(10):994\u2013998","journal-title":"Pediatr Infect Dis J"},{"issue":"1","key":"6294_CR3","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3390\/jcm8010101","volume":"8","author":"S Torretta","year":"2019","unstructured":"Torretta S, Guastella C, Marchisio P, Marom T, Bosis S, Ibba T et al (2019) Sinonasal-related orbital infections in children: a clinical and therapeutic overview. J Clin Med 8(1):101","journal-title":"J Clin Med"},{"issue":"5","key":"6294_CR4","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1097\/01.iop.0000179973.44003.f7","volume":"21","author":"MT Yen","year":"2005","unstructured":"Yen MT, Yen KG (2005) Effect of corticosteroids in the acute management of pediatric orbital cellulitis with subperiosteal abscess. Ophthal Plast Reconstr Surg 21(5):363\u2013366","journal-title":"Ophthal Plast Reconstr Surg"},{"issue":"6","key":"6294_CR5","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1136\/bjo.82.6.704","volume":"82","author":"RM Stanbury","year":"1998","unstructured":"Stanbury RM, Graham EM (1998) Systemic corticosteroid therapy\u2014side effects and their management. Br J Ophthalmol 82(6):704\u2013708","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"6294_CR6","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1097\/00004836-200110000-00006","volume":"33","author":"AL Buchman","year":"2001","unstructured":"Buchman AL (2001) Side effects of corticosteroid therapy. J Clin Gastroenterol 33(4):289\u2013294","journal-title":"J Clin Gastroenterol"},{"issue":"11","key":"6294_CR7","doi-asserted-by":"publisher","first-page":"CD012843","DOI":"10.1002\/14651858.CD012843","volume":"2017","author":"MJ Ravesloot","year":"2017","unstructured":"Ravesloot MJ, Lourijsen E, Avdeeva K, Pundir V, Fokkens W (2017) Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery. Cochrane Database Syst Rev 2017(11):CD012843. https:\/\/doi.org\/10.1002\/14651858.CD012843","journal-title":"Cochrane Database Syst Rev"},{"issue":"7","key":"6294_CR8","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","volume":"6","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 6(7):e1000097","journal-title":"PLoS Med."},{"issue":"9270","key":"6294_CR9","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1016\/S0140-6736(00)04934-5","volume":"357","author":"M Clarke","year":"2001","unstructured":"Clarke M, Horton R (2001) Bringing it all together: Lancet\u2013Cochrane collaborate on systematic reviews. Lancet 357(9270):1728","journal-title":"Lancet"},{"issue":"9193","key":"6294_CR10","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.1016\/S0140-6736(99)04149-5","volume":"354","author":"D Moher","year":"1999","unstructured":"Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF (1999) Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses. Lancet 354(9193):1896\u20131900","journal-title":"Lancet"},{"issue":"3","key":"6294_CR11","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","author":"R DerSimonian","year":"1986","unstructured":"DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7(3):177\u2013188","journal-title":"Control Clin Trials"},{"issue":"5","key":"6294_CR12","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1097\/IOP.0000000000000349","volume":"31","author":"BW Davies","year":"2015","unstructured":"Davies BW, Smith JM, Hink EM, Durairaj VD (2015) C-reactive protein as a marker for initiating steroid treatment in children with orbital cellulitis. Ophthal Plast Reconstr Surg 31(5):364\u2013368","journal-title":"Ophthal Plast Reconstr Surg"},{"issue":"1","key":"6294_CR13","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.ajo.2013.01.031","volume":"156","author":"N Pushker","year":"2013","unstructured":"Pushker N, Tejwani LK, Bajaj MS, Khurana S, Velpandian T, Chandra M (2013) Role of oral corticosteroids in orbital cellulitis. Am J Ophthalmol 156(1):178\u2013183","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"6294_CR14","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/IOP.0000000000000910","volume":"34","author":"L Chen","year":"2018","unstructured":"Chen L, Silverman N, Wu A, Shinder R (2018) Intravenous steroids with antibiotics on admission for children with orbital cellulitis. Ophthal Plast Reconstr Surg 34(3):205\u2013208","journal-title":"Ophthal Plast Reconstr Surg"},{"issue":"2","key":"6294_CR15","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1001\/archotol.127.2.188","volume":"127","author":"HH Ramadan","year":"2001","unstructured":"Ramadan HH (2001) Corticosteroid therapy during endoscopic sinus surgery in children. Arch Otolaryngol Neck Surg 127(2):188","journal-title":"Arch Otolaryngol Neck Surg"},{"issue":"6","key":"6294_CR16","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1080\/003655400459621","volume":"32","author":"P Gehanno","year":"2000","unstructured":"Gehanno P, Beauvillain C, Bobin S, Chobaut JC, Desaulty A, Dubreuil C et al (2000) Short therapy with amoxicillin\u2013clavulanate and corticosteroids in acute sinusitis: results of a multicentre study in adults. Scand J Infect Dis 32(6):679\u2013684","journal-title":"Scand J Infect Dis"},{"issue":"10","key":"6294_CR17","doi-asserted-by":"publisher","first-page":"577","DOI":"10.2165\/00044011-200424100-00003","volume":"24","author":"NP Ratau","year":"2004","unstructured":"Ratau NP, Snyman JR, Swanepoel C (2004) Short-course, low-dose oral betamethasone as an adjunct in the treatment of acute infective sinusitis. Clin Drug Investig 24(10):577\u2013582","journal-title":"Clin Drug Investig"},{"issue":"5","key":"6294_CR18","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/S0755-4982(04)98569-7","volume":"33","author":"J Klossek","year":"2004","unstructured":"Klossek J, Desmonts-Gohler C, Deslandes B, Coriat F, Bordure P, Dubreuil C et al (2004) Treatment of functional signs of acute maxillary rhinosinusitis in adults. Efficacy and tolerance of administration of oral prednisone for 3 days. Presse Med 33(5):303\u2013309","journal-title":"Presse Med"},{"issue":"3","key":"6294_CR19","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.bjoms.2019.01.010","volume":"57","author":"S Kent","year":"2019","unstructured":"Kent S, Hennedige A, McDonald C, Henry A, Dawoud B, Kulkarni R et al (2019) Systematic review of the role of corticosteroids in cervicofacial infections. Br J Oral Maxillofac Surg 57(3):196\u2013206","journal-title":"Br J Oral Maxillofac Surg"},{"key":"6294_CR20","first-page":"CD004405","volume":"9","author":"MC Brouwer","year":"2015","unstructured":"Brouwer MC, McIntyre P, Prasad K, van de Beek D (2015) Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev. 9:CD004405","journal-title":"Cochrane Database Syst Rev."},{"issue":"11","key":"6294_CR21","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1001\/jama.278.11.925","volume":"278","author":"PB McIntyre","year":"1997","unstructured":"McIntyre PB, Berkey CS, King SM, Schaad UB, Kilpi T, Kanra GY et al (1997) Dexamethasone as adjunctive therapy in bacterial meningitis. A meta-analysis of randomized clinical trials since 1988. JAMA 278(11):925\u2013931","journal-title":"JAMA"},{"issue":"20","key":"6294_CR22","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1056\/NEJMoa021334","volume":"347","author":"J de Gans","year":"2002","unstructured":"de Gans J, van de Beek D (2002) Dexamethasone in adults with bacterial meningitis. N Engl J Med 347(20):1549\u20131556","journal-title":"N Engl J Med"},{"issue":"22","key":"6294_CR23","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.1212\/WNL.0b013e31827595f7","volume":"79","author":"D Fritz","year":"2012","unstructured":"Fritz D, Brouwer MC, van de Beek D (2012) Dexamethasone and long-term survival in bacterial meningitis. Neurology 79(22):2177\u20132179","journal-title":"Neurology"},{"issue":"2","key":"6294_CR24","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.ijsu.2010.11.005","volume":"9","author":"D Muzumdar","year":"2011","unstructured":"Muzumdar D, Jhawar S, Goel A (2011) Brain abscess: an overview. Int J Surg 9(2):136\u2013144","journal-title":"Int J Surg"},{"issue":"4","key":"6294_CR25","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1177\/1457496915622129","volume":"105","author":"TK Nicoli","year":"2016","unstructured":"Nicoli TK, Oinas M, Niemel\u00e4 M, M\u00e4kitie AA, Atula T (2016) Intracranial suppurative complications of sinusitis. Scand J Surg 105(4):254\u2013262","journal-title":"Scand J Surg"},{"issue":"6","key":"6294_CR26","doi-asserted-by":"publisher","first-page":"1616","DOI":"10.1097\/00006534-199911000-00002","volume":"104","author":"LM Boon","year":"1999","unstructured":"Boon LM, MacDonald DM, Mulliken JB (1999) Complications of systemic corticosteroid therapy for problematic hemangioma. Plast Reconstr Surg 104(6):1616\u20131623","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"6294_CR27","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1017\/S1355617712001014","volume":"19","author":"C Mrakotsky","year":"2013","unstructured":"Mrakotsky C, Forbes PW, Bernstein JH, Grand RJ, Bousvaros A, Szigethy E et al (2013) Acute cognitive and behavioral effects of systemic corticosteroids in children treated for inflammatory bowel disease. J Int Neuropsychol Soc 19(1):96\u2013109","journal-title":"J Int Neuropsychol Soc"},{"issue":"1","key":"6294_CR28","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1111\/j.1525-1470.2012.01846.x","volume":"30","author":"K Nieuwenhuis","year":"2013","unstructured":"Nieuwenhuis K, de Laat PCJ, Janmohamed SR, Madern GC, Oranje AP (2013) Infantile hemangioma: treatment with short course systemic corticosteroid therapy as an alternative for propranolol. Pediatr Dermatol 30(1):64\u201370","journal-title":"Pediatr Dermatol"},{"issue":"6","key":"6294_CR29","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S0301-0546(05)73248-1","volume":"33","author":"WCN Forte","year":"2005","unstructured":"Forte WCN, Sumita JM, Rodrigues AG, Liuson D, Tanaka E (2005) Rebound phenomenon to systemic corticosteroid in atopic dermatitis. Allergol Immunopathol (Madr) 33(6):307\u2013311","journal-title":"Allergol Immunopathol (Madr)"},{"issue":"1","key":"6294_CR30","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1080\/00016489.2018.1539516","volume":"139","author":"T Tachibana","year":"2019","unstructured":"Tachibana T, Kariya S, Orita Y, Nakada M, Makino T, Haruna T et al (2019) Factors that prolong the duration of recovery in acute rhinosinusitis with orbital complications. Acta Otolaryngol 139(1):52\u201356","journal-title":"Acta Otolaryngol"},{"issue":"6","key":"6294_CR31","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1002\/alr.22535","volume":"10","author":"S Mahalingam","year":"2020","unstructured":"Mahalingam S, Hone R, Lloyd G, Grounds R, Shamil E, Wong G et al (2020) The management of periorbital cellulitis secondary to sinonasal infection: a multicenter prospective study in the United Kingdom. Int Forum Allergy Rhinol 10(6):726\u2013737","journal-title":"Int Forum Allergy Rhinol"},{"issue":"8","key":"6294_CR32","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1016\/S0161-6420(00)00242-6","volume":"107","author":"GH Garcia","year":"2000","unstructured":"Garcia GH, Harris GJ (2000) Criteria for nonsurgical management of subperiosteal abscess of the orbit: analysis of outcomes 1988\u20131998. Ophthalmology 107(8):1454\u20131458","journal-title":"Ophthalmology"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06294-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-020-06294-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06294-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T23:47:57Z","timestamp":1629762477000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-020-06294-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,24]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["6294"],"URL":"https:\/\/doi.org\/10.1007\/s00405-020-06294-z","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,24]]},"assertion":[{"value":"2 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}