{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T17:23:43Z","timestamp":1769361823653,"version":"3.49.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00405-020-06552-0","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T11:03:13Z","timestamp":1615460593000},"page":"2863-2868","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Decreased retinal nerve fiber and choroidal thickness in chronic rhinosinusitis"],"prefix":"10.1007","volume":"278","author":[{"given":"Refika Hande","family":"Karakahya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukadder","family":"Korkmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0988-4354","authenticated-orcid":false,"given":"Hakan","family":"Korkmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,11]]},"reference":[{"key":"6552_CR1","first-page":"1","volume":"10","author":"DL Blackwell","year":"2014","unstructured":"Blackwell DL, Lucas JW, Clarke TC (2014) Summary health statistics for U.S. adults: national health interview survey, 2012. Vital Health Stat 10:1\u2013171","journal-title":"Vital Health Stat"},{"issue":"5","key":"6552_CR2","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1002\/lio2.32","volume":"1","author":"SK Dennis","year":"2016","unstructured":"Dennis SK, Lam K, Luong A (2016) A review of classification schemes for chronic rhinosinusitis with nasal polyposis endotypes. Laryngoscope Investig Otolaryngol 1(5):130\u2013134","journal-title":"Laryngoscope Investig Otolaryngol"},{"issue":"4","key":"6552_CR3","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/j.jaip.2016.12.027","volume":"5","author":"WW Stevens","year":"2017","unstructured":"Stevens WW, Peters AT, Hirsch AG et al (2017) Clinical characteristics of patients with chronic rhinosinusitis with nasal polyps, asthma, and aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract 5(4):1061\u20131070","journal-title":"J Allergy Clin Immunol Pract"},{"key":"6552_CR4","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1398-9995.2007.01545.x","volume":"63","author":"G Hens","year":"2008","unstructured":"Hens G, Vanaudenaerde BM, Bullens DM et al (2008) Sinonasal pathology in nonallergic asthma and COPD:-united airway disease- beyond the scope of allergy. Allergy 63:261\u2013267","journal-title":"Allergy"},{"issue":"3","key":"6552_CR5","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1080\/080370599439698","volume":"8","author":"R \u00d6zdemir","year":"1999","unstructured":"\u00d6zdemir R, Yorulmaz A, Kutlu R et al (1999) Loss of nocturnal decline of blood pressure in patients with nasal polyposis. Blood Press 8(3):165\u2013171","journal-title":"Blood Press"},{"key":"6552_CR6","doi-asserted-by":"publisher","unstructured":"Entezari M, Karimi S, Ramezani A, et al. Choroidal thickness in healthy subjects. J Ophthalmic Vis Res. 2018 Jan-Mar;13(1):39\u201343. https:\/\/doi.org\/10.4103\/jovr.jovr_148_16. PMID: 29403588; PMCID: PMC5782455.","DOI":"10.4103\/jovr.jovr_148_16"},{"key":"6552_CR7","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/crj.12523","volume":"12","author":"E Ugurlu","year":"2018","unstructured":"Ugurlu E, Pekel G, Altinisik G et al (2018) New aspect for systemic effects of COPD: eye findings. Clin Respir J 12:247\u2013252","journal-title":"Clin Respir J"},{"issue":"3","key":"6552_CR8","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1080\/00325481.2016.1159118","volume":"128","author":"G Ozge","year":"2016","unstructured":"Ozge G, Dogan D, Koylu MT et al (2016) Retina nerve fiber layer and choroidal thickness changes in obstructive sleep apnea syndrome. Postgrad Med 128(3):317\u2013322","journal-title":"Postgrad Med"},{"issue":"8","key":"6552_CR9","doi-asserted-by":"publisher","first-page":"1218","DOI":"10.1016\/j.ijporl.2015.05.017","volume":"79","author":"E Cinici","year":"2015","unstructured":"Cinici E, Tatar A (2015) Thickness alterations of retinal nerve fiber layer in children with sleep-disordered breathing due to adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 79(8):1218\u20131223","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"6552_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4193\/Rhino50E2","volume":"50","author":"WJ Fokkens","year":"2012","unstructured":"Fokkens WJ, Lund VJ, Mullol J et al (2012) EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 50:1\u201312","journal-title":"Rhinology"},{"key":"6552_CR11","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1002\/lary.24581","volume":"124","author":"SD Chung","year":"2014","unstructured":"Chung SD, Chen PY, Lin HC, Hung SH (2014) Comorbidity profile of chronic rhinosinusitis: a population-based study. Laryngoscope 124:1536\u20131541","journal-title":"Laryngoscope"},{"issue":"5","key":"6552_CR12","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1002\/alr.22289","volume":"9","author":"Q Orb","year":"2019","unstructured":"Orb Q, Pulsipher A, Smith KA et al (2019) Correlation between systemic inflammatory response and quality of life in patients with chronic rhinosinusitis. Int Forum Allergy Rhinol 9(5):458\u2013465","journal-title":"Int Forum Allergy Rhinol"},{"key":"6552_CR13","doi-asserted-by":"publisher","first-page":"023","DOI":"10.23937\/2378-3516\/1410023","volume":"2","author":"K Matsumoto","year":"2015","unstructured":"Matsumoto K, Kawayama T, Kinoshita T et al (2015) Chronic rhinosinusitis is associated with airflow obstruction in japanese never-smokers without asthma. Int J Respir Pulm Med 2:023","journal-title":"Int J Respir Pulm Med"},{"issue":"21\u201344","key":"6552_CR14","first-page":"14","volume":"30","author":"FX McGowan Jr","year":"1992","unstructured":"McGowan FX Jr (1992) Cardiovascular and airway interactions. Int Anesthesiol Clin 30(21\u201344):14","journal-title":"Int Anesthesiol Clin"},{"issue":"3","key":"6552_CR15","doi-asserted-by":"publisher","first-page":"e0193886","DOI":"10.1371\/journal.pone.0193886","volume":"13","author":"WH Lee","year":"2018","unstructured":"Lee WH, Kim JW, Lim JS et al (2018) Chronic rhinosinusitis increases the risk of hemorrhagic and ischemic stroke: A longitudinal follow-up study using a national sample cohort. PLoS ONE 13(3):e0193886","journal-title":"PLoS ONE"},{"key":"6552_CR16","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1001\/archotol.126.8.940","volume":"126","author":"JE Lieu","year":"2000","unstructured":"Lieu JE, Feinstein AR (2000) Confirmations and surprises in the association of tobacco use with sinusitis. Arch Otolaryngol Head Neck Surg 126:940\u2013946","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"1","key":"6552_CR17","doi-asserted-by":"publisher","first-page":"53","DOI":"10.5935\/0004-2749.20180012","volume":"81","author":"AIA Unsal","year":"2018","unstructured":"Unsal AIA, Basal Y, Birincioglu S et al (2018) Ophthalmic adverse effects of nasal decongestants on an experimental rat model. Arquivos Brasileiros de Oftalmologia 81(1):53\u201358","journal-title":"Arquivos Brasileiros de Oftalmologia"},{"issue":"1","key":"6552_CR18","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1186\/1752-1947-4-350","volume":"4","author":"A Garg","year":"2010","unstructured":"Garg A, Das-Bhaumik R, Nesbitt AD et al (2010) Visual loss secondary to eosinophilic mucin rhinosinusitis in a woman: a case report. J Med Case Reports 4(1):350","journal-title":"J Med Case Reports"},{"key":"6552_CR19","doi-asserted-by":"publisher","first-page":"853","DOI":"10.2147\/OPTH.S22713","volume":"5","author":"T Kurimoto","year":"2011","unstructured":"Kurimoto T, Tonari M, Ishizaki N et al (2011) A case of eosinophilic chronic rhinosinusitis associated with optic neuropathy. Clin Ophthalmol 5:853\u2013856","journal-title":"Clin Ophthalmol"},{"key":"6552_CR20","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1159\/000497270","volume":"10","author":"M Ikeda","year":"2019","unstructured":"Ikeda M, Iwahashi C, Hirai T et al (2019) A case of eosinophilic chronic rhinosinusitis associated with choroidal folds and ocular motility disorder. Case Rep Ophthalmol 10:89\u201394","journal-title":"Case Rep Ophthalmol"},{"issue":"5","key":"6552_CR21","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1080\/02713683.2016.1238942","volume":"42","author":"W Wang","year":"2017","unstructured":"Wang W, He M, Huang W (2017) Changes of retinal nerve fiber layer thickness in obstructive sleep apnea syndrome: a systematic review and meta-analysis. Curr Eye Res 42(5):796\u2013802","journal-title":"Curr Eye Res"},{"issue":"3","key":"6552_CR22","doi-asserted-by":"publisher","first-page":"227","DOI":"10.4193\/Rhin18.005","volume":"56","author":"WC Chen","year":"2018","unstructured":"Chen WC, Chang YT, Chen SF et al (2018) The symptom burden of autonomic dysfunction is positively associated with chronic rhinosinusitis status. Rhinology 56(3):227\u2013233","journal-title":"Rhinology"},{"issue":"5","key":"6552_CR23","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/S1350-9462(01)00004-0","volume":"20","author":"SS Hayreh","year":"2001","unstructured":"Hayreh SS (2001) The blood supply of the optic nerve head and the evaluation of it - myth and reality. Prog Retin Eye Res 20(5):563\u2013593","journal-title":"Prog Retin Eye Res"},{"issue":"5","key":"6552_CR24","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.survophthal.2016.02.007","volume":"61","author":"KA Tan","year":"2016","unstructured":"Tan KA, Gupta P, Agarwal A et al (2016) State of science: Choroidal thickness and systemic health. Surv Ophthalmol 61(5):566\u2013581","journal-title":"Surv Ophthalmol"},{"issue":"22","key":"6552_CR25","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1056\/NEJM199105303242203","volume":"324","author":"AT Dinh-Xuan","year":"1991","unstructured":"Dinh-Xuan AT, Higenbottam TW, Clelland CA et al (1991) Impairment of endothelium-dependent pulmonary-artery relaxation in chronic obstructive lung disease. N Engl J Med 324(22):1539\u20131547","journal-title":"N Engl J Med"},{"issue":"3","key":"6552_CR26","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.2500\/ajra.2016.30.4325","volume":"30","author":"OC Elcioglu","year":"2016","unstructured":"Elcioglu OC, Afsar B, Bakan A et al (2016) Chronic rhinosinusitis, endothelial dysfunction, and atherosclerosis. Am J Rhinol Allergy 30(3):e58\u2013e61","journal-title":"Am J Rhinol Allergy"},{"issue":"5","key":"6552_CR27","doi-asserted-by":"publisher","first-page":"381","DOI":"10.2500\/ajra.2013.27.3934","volume":"27","author":"SL Oyer","year":"2013","unstructured":"Oyer SL, Nagel W, Mulligan JK (2013) Differential expression of adhesion molecules by sinonasal fibroblasts among control and chronic rhinosinusitis patients. Am J Rhinol Allergy 27(5):381\u2013386","journal-title":"Am J Rhinol Allergy"},{"issue":"11","key":"6552_CR28","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.3109\/02713683.2014.898310","volume":"39","author":"H Altinkaynak","year":"2014","unstructured":"Altinkaynak H, Kara N, Say\u0131n N et al (2014) Subfoveal choroidal thickness in patients with chronic heart failure analyzed by spectral-domain optical coherence tomography. Curr Eye Res 39(11):1123\u20131128","journal-title":"Curr Eye Res"},{"key":"6552_CR29","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s11325-015-1306-8","volume":"20","author":"M He","year":"2016","unstructured":"He M, Han X, Wu H et al (2016) Choroidal thickness changes in obstructive sleep apnea syndrome: a systematic review and meta-analysis. Sleep Breath 20:369\u2013378","journal-title":"Sleep Breath"},{"key":"6552_CR30","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1016\/S0140-6736(05)71141-7","volume":"365","author":"JM Marin","year":"2005","unstructured":"Marin JM, Carrizo SJ, Vicente E, Agusti AG (2005) Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 365:1046\u20131053","journal-title":"Lancet"},{"key":"6552_CR31","doi-asserted-by":"publisher","first-page":"1201976","DOI":"10.1155\/2018\/1201976","volume":"2018","author":"\u00d6 Kocam\u0131\u015f","year":"2018","unstructured":"Kocam\u0131\u015f \u00d6, Zorlu D (2018) Choroid and retinal nerve fiber layer thickness in patients with chronic obstructive pulmonary disease exacerbation. J Ophthalmol 2018:1201976","journal-title":"J Ophthalmol"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06552-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-020-06552-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-020-06552-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T04:12:59Z","timestamp":1625717579000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-020-06552-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,11]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["6552"],"URL":"https:\/\/doi.org\/10.1007\/s00405-020-06552-0","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,11]]},"assertion":[{"value":"29 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Authors declare that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}