{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:43:03Z","timestamp":1793644983946,"version":"4.5.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1007\/s00405-021-06685-w","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T13:03:28Z","timestamp":1615381408000},"page":"4491-4500","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intra- and postoperative complications using LigaSure\u2122 Small Jaw in patients undergoing thyroidectomy: a register-based study"],"prefix":"10.1007","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9032-7813","authenticated-orcid":false,"given":"Anne Yoon Krogh","family":"Gr\u00f8ndal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"H\u00f8gsbro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasper","family":"Pryds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik Baymler","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,10]]},"reference":[{"issue":"4","key":"6685_CR1","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.otohns.2009.06.745","volume":"141","author":"Y Pons","year":"2009","unstructured":"Pons Y, Gauthier J, Ukkola-Pons E, Clement P, Roguet E, Poncet JL, Conessa C (2009) Comparison of LigaSure vessel sealing system, harmonic scalpel, and conventional hemostasis in total thyroidectomy. Otolaryngol Head Neck Surg 141(4):496\u2013501. https:\/\/doi.org\/10.1016\/j.otohns.2009.06.745","journal-title":"Otolaryngol Head Neck Surg"},{"key":"6685_CR2","unstructured":"JL G (1996) Total thyroidectomy. In: Bailey BJ, Calhoun KH (eds) Atlas of head and neck surgery: otolaryngology, 2nd ed"},{"issue":"8","key":"6685_CR3","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1007\/s004640080025","volume":"15","author":"BT Heniford","year":"2001","unstructured":"Heniford BT, Matthews BD, Sing RF, Backus C, Pratt B, Greene FL (2001) Initial results with an electrothermal bipolar vessel sealer. Surg Endosc 15(8):799\u2013801. https:\/\/doi.org\/10.1007\/s004640080025","journal-title":"Surg Endosc"},{"issue":"11","key":"6685_CR4","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1002\/hed.20271","volume":"27","author":"A Manouras","year":"2005","unstructured":"Manouras A, Lagoudianakis EE, Antonakis PT, Filippakis GM, Markogiannakis H, Kekis PB (2005) Electrothermal bipolar vessel sealing system is a safe and time-saving alternative to classic suture ligation in total thyroidectomy. Head Neck 27(11):959\u2013962. https:\/\/doi.org\/10.1002\/hed.20271","journal-title":"Head Neck"},{"issue":"1","key":"6685_CR5","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.amjsurg.2007.01.037","volume":"195","author":"A Manouras","year":"2008","unstructured":"Manouras A, Markogiannakis H, Koutras AS, Antonakis PT, Drimousis P, Lagoudianakis EE, Kekis P, Genetzakis M, Koutsoumanis K, Bramis I (2008) Thyroid surgery: comparison between the electrothermal bipolar vessel sealing system, harmonic scalpel, and classic suture ligation. Am J Surg 195(1):48\u201352. https:\/\/doi.org\/10.1016\/j.amjsurg.2007.01.037","journal-title":"Am J Surg"},{"issue":"4","key":"6685_CR6","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.ijsu.2008.05.005","volume":"6","author":"T Youssef","year":"2008","unstructured":"Youssef T, Mahdy T, Farid M, Latif AA (2008) Thyroid surgery: use of the LigaSure Vessel Sealing System versus conventional knot tying. Int J Surg 6(4):323\u2013327. https:\/\/doi.org\/10.1016\/j.ijsu.2008.05.005","journal-title":"Int J Surg"},{"key":"6685_CR7","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1758-3284-4-2","volume":"4","author":"AH Schiphorst","year":"2012","unstructured":"Schiphorst AH, Twigt BA, Elias SG, van Dalen T (2012) Randomized clinical trial of LigaSure versus conventional suture ligation in thyroid surgery. Head Neck Oncol 4:2. https:\/\/doi.org\/10.1186\/1758-3284-4-2","journal-title":"Head Neck Oncol"},{"issue":"2","key":"6685_CR8","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1001\/archsurg.142.2.150","volume":"142","author":"O Saint Marc","year":"2007","unstructured":"Saint Marc O, Cogliandolo A, Piquard A, Fama F, Pidoto RR (2007) LigaSure vs clamp-and-tie technique to achieve hemostasis in total thyroidectomy for benign multinodular goiter: a prospective randomized study. Arch Surg 142(2):150\u2013156. https:\/\/doi.org\/10.1001\/archsurg.142.2.150 (discussion 157)","journal-title":"Arch Surg"},{"key":"6685_CR9","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ijsu.2016.08.241","volume":"37","author":"O Vidal","year":"2017","unstructured":"Vidal O, Saavedra-Perez D, Valentini M, Astudillo E, Fernandez-Cruz L, Garcia-Valdecasas JC (2017) Surgical outcomes of total thyroidectomy using the LigaSure Small Jaw versus LigaSure Precise: a retrospective study of 2000 consecutive patients. Int J Surg 37:8\u201312. https:\/\/doi.org\/10.1016\/j.ijsu.2016.08.241","journal-title":"Int J Surg"},{"issue":"5","key":"6685_CR10","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1007\/s00405-018-4912-9","volume":"275","author":"XC Mao","year":"2018","unstructured":"Mao XC, Chen C, Wang KJ (2018) Efficacy and safety of LigaSure small jaw instrument in thyroidectomy: a 1-year prospective observational study. Eur Arch Otorhinolaryngol 275(5):1257\u20131263. https:\/\/doi.org\/10.1007\/s00405-018-4912-9","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"6","key":"6685_CR11","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/j.anl.2013.04.005","volume":"40","author":"A Kuboki","year":"2013","unstructured":"Kuboki A, Nakayama T, Konno W, Goto K, Nakajima I, Kanaya H, Hirabayashi H, Haruna S (2013) New technique using an energy-based device versus conventional technique in open thyroidectomy. Auris Nasus Larynx 40(6):558\u2013562. https:\/\/doi.org\/10.1016\/j.anl.2013.04.005","journal-title":"Auris Nasus Larynx"},{"issue":"7","key":"6685_CR12","doi-asserted-by":"publisher","first-page":"2109","DOI":"10.1007\/s00405-012-2289-8","volume":"270","author":"P Hirunwiwatkul","year":"2013","unstructured":"Hirunwiwatkul P, Tungkavivachagul S (2013) A multicenter, randomized, controlled clinical trial of LigaSure small jaw vessel sealing system versus conventional technique in thyroidectomy. Eur Arch Otorhinolaryngol 270(7):2109\u20132114. https:\/\/doi.org\/10.1007\/s00405-012-2289-8","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"5","key":"6685_CR13","first-page":"608","volume":"109","author":"C Molnar","year":"2014","unstructured":"Molnar C, Voidazan S, Rad CC, Neagoe VI, Rosca C, Barna L, Copotoiu C (2014) Total thyroidectomy with LigaSure Small Jaw versus conventional thyroidectomy\u2014a clinical study. Chirurgia (Bucur) 109(5):608\u2013612","journal-title":"Chirurgia (Bucur)"},{"issue":"2","key":"6685_CR14","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/s00423-014-1270-y","volume":"400","author":"S Coiro","year":"2015","unstructured":"Coiro S, Frattaroli FM, De Lucia F, Manna E, Fabi F, Frattaroli JM, Pappalardo G (2015) A comparison of the outcome using Ligasure small jaw and clamp-and-tie technique in thyroidectomy: a randomized single center study. Langenbecks Arch Surg 400(2):247\u2013252. https:\/\/doi.org\/10.1007\/s00423-014-1270-y","journal-title":"Langenbecks Arch Surg"},{"issue":"1","key":"6685_CR15","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/s12957-018-1448-9","volume":"16","author":"A Ramouz","year":"2018","unstructured":"Ramouz A, Rasihashemi SZ, Safaeiyan A, Hosseini M (2018) Comparing postoperative complication of LigaSure Small Jaw instrument with clamp and tie method in thyroidectomy patients: a randomized controlled trial [IRCT2014010516077N1]. World J Surg Oncol 16(1):154. https:\/\/doi.org\/10.1186\/s12957-018-1448-9","journal-title":"World J Surg Oncol"},{"issue":"14","key":"6685_CR16","first-page":"1997","volume":"18","author":"HY Bircan","year":"2014","unstructured":"Bircan HY, Inal A, Ozcelik U, Koc B, Demirag A, Moray G, Kemik O (2014) LigaSure(R) versus clamp tie technique for thyroid surgery; decreased operative time versus increased inflammatory effect: a prospective randomized study. Eur Rev Med Pharmacol Sci 18(14):1997\u20132005","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"12","key":"6685_CR17","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1007\/s00405-009-0949-0","volume":"266","author":"C Godballe","year":"2009","unstructured":"Godballe C, Madsen AR, Pedersen HB, Sorensen CH, Pedersen U, Frisch T, Helweg-Larsen J, Barfoed L, Illum P, Monsted JE, Becker B, Nielsen T (2009) Post-thyroidectomy hemorrhage: a national study of patients treated at the Danish departments of ENT Head and Neck Surgery. Eur Arch Otorhinolaryngol 266(12):1945\u20131952. https:\/\/doi.org\/10.1007\/s00405-009-0949-0","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"6685_CR18","unstructured":"Medtronic (2018) https:\/\/www.medtronic.com\/covidien\/en-us\/products\/vessel-sealing\/ligasure-small-jaw.html"},{"issue":"7\u20138","key":"6685_CR19","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1111\/j.1445-2197.2010.05492.x","volume":"81","author":"LY Chang","year":"2011","unstructured":"Chang LY, O\u2019Neill C, Suliburk J, Sidhu S, Delbridge L, Sywak M (2011) Sutureless total thyroidectomy: a safe and cost-effective alternative. ANZ J Surg 81(7\u20138):510\u2013514","journal-title":"ANZ J Surg"},{"issue":"9","key":"6685_CR20","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1089\/thy.2012.0588","volume":"23","author":"G Garas","year":"2013","unstructured":"Garas G, Okabayashi K, Ashrafian H, Shetty K, Palazzo F, Tolley N, Darzi A, Athanasiou T, Zacharakis E (2013) Which hemostatic device in thyroid surgery? A network meta-analysis of surgical technologies. Thyroid 23(9):1138\u20131150. https:\/\/doi.org\/10.1089\/thy.2012.0588","journal-title":"Thyroid"},{"issue":"1","key":"6685_CR21","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1007\/s00405-016-4213-0","volume":"274","author":"J Tian","year":"2017","unstructured":"Tian J, Li L, Liu P, Wang X (2017) Comparison of drain versus no-drain thyroidectomy: a meta-analysis. Eur Arch Otorhinolaryngol 274(1):567\u2013577. https:\/\/doi.org\/10.1007\/s00405-016-4213-0","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"9","key":"6685_CR22","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1097\/01.mlg.0000231314.86486.be","volume":"116","author":"SW Lee","year":"2006","unstructured":"Lee SW, Choi EC, Lee YM, Lee JY, Kim SC, Koh YW (2006) Is lack of placement of drains after thyroidectomy with central neck dissection safe? A prospective, randomized study. Laryngoscope 116(9):1632\u20131635. https:\/\/doi.org\/10.1097\/01.mlg.0000231314.86486.be","journal-title":"Laryngoscope"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-021-06685-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-021-06685-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-021-06685-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T05:29:11Z","timestamp":1633066151000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-021-06685-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,10]]},"references-count":22,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["6685"],"URL":"https:\/\/doi.org\/10.1007\/s00405-021-06685-w","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,10]]},"assertion":[{"value":"1 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no conflict of interests or competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}