{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T10:10:27Z","timestamp":1775211027482,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T00:00:00Z","timestamp":1615593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T00:00:00Z","timestamp":1615593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100008967","name":"Philipps-Universit\u00e4t Marburg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008967","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Reprocessing of flexible endoscopes (FEs) is often expensive, time consuming, and becomes increasingly complex, due to rising demands of hygiene. After beneficial results in reprocessing of rigid endoscopes using Impelux\u2122 UV-C light technology, we tested the same method for reprocessing of FEs without working channel.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>Testing was performed on FEs without working channel after routine clinical use (transnasal flexible endoscopy). Disinfection consisted of mechanical precleaning and 60\u00a0s exposure to Impelux\u2122 UV-C light technology. Bacterial contamination was tested on 50 FEs before and after disinfection. Further 50 FEs regarding protein residuals. The absolute effectiveness of the D60 was tested on 50 test bodies (RAMS) with a standardized contamination of 10<jats:sup>7<\/jats:sup> colony-forming units (CFU) of Enterococcus faecium.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The FEs were contaminated with a high average value of 916.7\u00a0CFU (\u00b1\u20091057\u00a0CFU) after clinical usage. After reprocessing, an average contamination of 2.8\u00a0CFU (\u00b1\u20091.6) on 14% (<jats:italic>n<\/jats:italic>\u2009=\u20097) of the FEs was detected consisting of non-pathogenic species, the remaining FE were sterile. After reprocessing, all FEs were protein-free (&lt;\u20091\u00a0\u03bcg). The artificially contaminated test bodies showed no remaining bacterial contamination after disinfection, resulting in an average absolute germ reduction of about 10<jats:sup>7<\/jats:sup>\u00a0CFU.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Impelux\u2122 UV-C light technology efficiently reduces bacterial contamination of FEs and might be useful in daily practice.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-021-06737-1","type":"journal-article","created":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T10:02:27Z","timestamp":1615629747000},"page":"4075-4080","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["UV light-based reprocessing of flexible endoscopes without working channel in Oto-Rhino-Laryngology: an effective method?"],"prefix":"10.1007","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3580-4255","authenticated-orcid":false,"given":"Stefan A.","family":"Rudhart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"G\u00fcnther","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Dapper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kruthika","family":"Thangavelu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urban W.","family":"Geisthoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Stankovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris A.","family":"Stuck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Hoch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,13]]},"reference":[{"issue":"8","key":"6737_CR1","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1007\/s00405-020-05978-w","volume":"277","author":"SA Rudhart","year":"2020","unstructured":"Rudhart SA, G\u00fcnther F, Dapper L, Thangavelu K, Gehrt F, Stankovic P, Wilhelm T, Guenzel T, Stuck BA, Hoch S (2020) UV light-based decontamination: an effective and fast way for disinfection of endoscopes in otorhinolaryngology? 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