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The aim of this study was to report the outcome in our centre.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective chart analysis with survival analyses was performed combined with\u00a0fluorescence in situ hybridization (FISH) analysis to assess CRTC1\/3 MAML 2 fusion gene presence.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty-four cases of MEC were identified. Median age at presentation was 51.4\u00a0years with a predominance for parotid gland involvement.\u00a0Five, 10- and 20- year disease-free survival was 98%, 90% and 68%, respectively. Overall survival was 94%, 90% and 64%, respectively. Local recurrence was seen up to 14\u00a0years after primary diagnosis; distant metastases were diagnosed up to 17\u00a0years later. The overall recurrence rate was less than 20 per cent. CRTC1\/3 MAML 2 fusion gene presence showed no survival benefit.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>MEC of the head and neck has a favorable outcome with the exception of high-grade MEC. PNI and nodal involvement are not rare. CRTC1\/3 MAML 2 fusion gene presence showed no survival benefit. The tendency for late onset of loco-regional and distant recurrence should not be underestimated.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-021-07039-2","type":"journal-article","created":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T18:02:54Z","timestamp":1629223374000},"page":"2573-2581","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Mucoepidermoid carcinoma of the head and neck: CRTC1\/3 MAML 2 translocation and its prognosticators"],"prefix":"10.1007","volume":"279","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7759-7461","authenticated-orcid":false,"given":"Stijn","family":"van Weert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit I.","family":"Lissenberg-Witte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Bloemena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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