{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T14:36:45Z","timestamp":1782571005599,"version":"3.54.5"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T00:00:00Z","timestamp":1640476800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T00:00:00Z","timestamp":1640476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Bergen"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Exercise-induced laryngeal obstruction (EILO) is relatively common in young people. Treatment rests on poor evidence; however, inspiratory muscle training (IMT) has been proposed a promising strategy. We aimed to assess laryngeal outcomes shortly after IMT, and to compare self-reported symptoms with a control group 4\u20136\u00a0years later.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Two groups were retrospectively identified from the <jats:italic>EILO-register<\/jats:italic> at Haukeland University Hospital, Norway; one group had received only information and breathing advice (IBA), and another additionally IMT (IBA\u2009+\u2009IMT). At diagnosis, all participants performed continuous laryngoscopy during exercise (CLE), with findings split by glottic and supraglottic scores, and completed a questionnaire mapping exercise-related symptoms. After 2\u20134\u00a0weeks, the IBA\u2009+\u2009IMT-group was re-evaluated with CLE-test. After 4\u20136\u00a0years, both groups were re-assessed with a questionnaire.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We identified 116 eligible patients from the <jats:italic>EILO-register<\/jats:italic>. Response rates after 4\u20136\u00a0years were 23\/58 (40%) and 32\/58 (55%) in the IBA and IBA\u2009+\u2009IMT-group, respectively. At diagnosis, both groups rated symptoms similarly, but laryngeal scores were higher in the IBA\u2009+\u2009IMT-group (<jats:italic>P<\/jats:italic>\u2009=\u20090.003). After 2\u20134\u00a0weeks, 23\/32 in the IBA\u2009+\u2009IMT-group reported symptom improvements, associated with a decrease of mainly glottic scores (1.7\u20130.3; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), contrasting unchanged scores in the 9\/32 without symptom improvements. After 4\u20136\u00a0years, exercise-related symptoms and activity levels had decreased to similar levels in both groups, with no added benefit from IMT; however, full symptom resolution was reported by only 8\/55 participants.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Self-reported EILO symptoms had improved after 4\u20136\u00a0years, irrespective of initial treatment. Full symptom resolution was rare, suggesting individual follow-up should be offered.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-021-07214-5","type":"journal-article","created":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T14:02:13Z","timestamp":1640527333000},"page":"2511-2522","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction"],"prefix":"10.1007","volume":"279","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0309-6314","authenticated-orcid":false,"given":"Astrid","family":"Sandnes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiina","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hege Havstad","family":"Clemm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Hilland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John-Helge","family":"Heimdal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Halvorsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola Drange","family":"R\u00f8ksund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Volls\u00e6ter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,26]]},"reference":[{"key":"7214_CR1","first-page":"86","volume":"21","author":"OD Roksund","year":"2017","unstructured":"Roksund OD et al (2017) Exercise inducible laryngeal obstruction: diagnostics and management. Paediatr Respir Rev 21:86\u201394","journal-title":"Paediatr Respir Rev"},{"issue":"9","key":"7214_CR2","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1007\/s00405-011-1612-0","volume":"268","author":"PM Christensen","year":"2011","unstructured":"Christensen PM et al (2011) Exercise-induced laryngeal obstructions: prevalence and symptoms in the general public. Eur Arch Otorhinolaryngol 268(9):1313\u20131319","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"7214_CR3","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1136\/thoraxjnl-2014-205738","volume":"70","author":"H Johansson","year":"2015","unstructured":"Johansson H et al (2015) Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population. Thorax 70(1):57\u201363","journal-title":"Thorax"},{"issue":"4","key":"7214_CR4","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1007\/s00405-016-4338-1","volume":"274","author":"S Liyanagedera","year":"2017","unstructured":"Liyanagedera S, McLeod R, Elhassan HA (2017) Exercise induced laryngeal obstruction: a review of diagnosis and management. Eur Arch Otorhinolaryngol 274(4):1781\u20131789","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"7214_CR5","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.1016\/j.jaip.2020.01.057","volume":"8","author":"JH Hull","year":"2020","unstructured":"Hull JH, Godbout K, Boulet LP (2020) Exercise-associated dyspnea and stridor: thinking beyond asthma. J Allergy Clin Immunol Pract 8:2202\u20132208","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"1","key":"7214_CR6","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.pop.2007.09.005","volume":"35","author":"M Hicks","year":"2008","unstructured":"Hicks M, Brugman SM, Katial R (2008) Vocal cord dysfunction\/paradoxical vocal fold motion. Prim Care 35(1):81\u2013103, vii","journal-title":"Prim Care"},{"issue":"1","key":"7214_CR7","doi-asserted-by":"publisher","first-page":"125 e7","DOI":"10.1016\/j.jvoice.2015.11.027","volume":"31","author":"AC Shembel","year":"2017","unstructured":"Shembel AC, Sandage MJ, Verdolini Abbott K (2017) Episodic laryngeal breathing disorders: literature review and proposal of preliminary theoretical framework. J Voice 31(1):125 e7-125 e16","journal-title":"J Voice"},{"issue":"5","key":"7214_CR8","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1183\/09031936.03.00095803","volume":"22","author":"K Yeatts","year":"2003","unstructured":"Yeatts K et al (2003) Health consequences associated with frequent wheezing in adolescents without asthma diagnosis. Eur Respir J 22(5):781\u2013786","journal-title":"Eur Respir J"},{"issue":"6","key":"7214_CR9","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1016\/j.rmed.2014.03.010","volume":"108","author":"H Johansson","year":"2014","unstructured":"Johansson H et al (2014) Exercise-induced dyspnea is a problem among the general adolescent population. Respir Med 108(6):852\u2013858","journal-title":"Respir Med"},{"issue":"1","key":"7214_CR10","doi-asserted-by":"publisher","first-page":"1399033","DOI":"10.1080\/20018525.2017.1399033","volume":"4","author":"KK Mirza","year":"2017","unstructured":"Mirza KK, Walsted ES, Backer V (2017) Ergospirometry with concurrent fibre optic laryngoscopy: a randomised crossover study. Eur Clin Respir J 4(1):1399033","journal-title":"Eur Clin Respir J"},{"issue":"1","key":"7214_CR11","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/01.mlg.0000184528.16229.ba","volume":"116","author":"JH Heimdal","year":"2006","unstructured":"Heimdal JH et al (2006) Continuous laryngoscopy exercise test: a method for visualizing laryngeal dysfunction during exercise. Laryngoscope 116(1):52\u201357","journal-title":"Laryngoscope"},{"issue":"3","key":"7214_CR12","doi-asserted-by":"publisher","first-page":"1602221","DOI":"10.1183\/13993003.02221-2016","volume":"50","author":"TW Halvorsen","year":"2017","unstructured":"Halvorsen TW, Bucca C, Bush A, Cantarella G, Friedrich G, Felix JF, Herth FJF, Hull JH, Jung H, Maat R, Nordang L, Remacle M, Rasmussen JA, Heimdal J-H (2017) Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement. Eur Respir J 50(3):1602221","journal-title":"Eur Respir J"},{"issue":"12","key":"7214_CR13","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1007\/s00405-009-1030-8","volume":"266","author":"RC Maat","year":"2009","unstructured":"Maat RC et al (2009) Audiovisual assessment of exercise-induced laryngeal obstruction: reliability and validity of observations. Eur Arch Otorhinolaryngol 266(12):1929\u20131936","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"2","key":"7214_CR14","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1183\/20734735.007216","volume":"12","author":"J Depiazzi","year":"2016","unstructured":"Depiazzi J, Everard ML (2016) Dysfunctional breathing and reaching one\u2019s physiological limit as causes of exercise-induced dyspnoea. Breathe (Sheff) 12(2):120\u2013129","journal-title":"Breathe (Sheff)"},{"issue":"1","key":"7214_CR15","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1136\/thx.2009.118521","volume":"65","author":"J Yorke","year":"2010","unstructured":"Yorke J et al (2010) Quantification of dyspnoea using descriptors: development and initial testing of the Dyspnoea-12. Thorax 65(1):21\u201326","journal-title":"Thorax"},{"key":"7214_CR16","doi-asserted-by":"publisher","first-page":"109765","DOI":"10.1016\/j.ijporl.2019.109765","volume":"129","author":"K Norlander","year":"2020","unstructured":"Norlander K et al (2020) Differences in laryngeal movements during exercise in healthy and dyspnoeic adolescents. Int J Pediatr Otorhinolaryngol 129:109765","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"2","key":"7214_CR17","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.iac.2018.01.003","volume":"38","author":"M Shaffer","year":"2018","unstructured":"Shaffer M et al (2018) Speech-language pathology as a primary treatment for exercise-induced laryngeal obstruction. Immunol Allergy Clin N Am 38(2):293\u2013302","journal-title":"Immunol Allergy Clin N Am"},{"issue":"1","key":"7214_CR18","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.ijporl.2011.09.017","volume":"76","author":"A Rameau","year":"2012","unstructured":"Rameau A et al (2012) Multidisciplinary approach to vocal cord dysfunction diagnosis and treatment in one session: a single institutional outcome study. Int J Pediatr Otorhinolaryngol 76(1):31\u201335","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"6","key":"7214_CR19","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/j.jvoice.2017.08.020","volume":"32","author":"KL Johnston","year":"2018","unstructured":"Johnston KL et al (2018) The Olin EILOBI breathing techniques: description and initial case series of novel respiratory retraining strategies for athletes with exercise-induced laryngeal obstruction. J Voice 32(6):698\u2013704","journal-title":"J Voice"},{"issue":"22","key":"7214_CR20","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1002\/lio2.257","volume":"4","author":"K Siewers","year":"2019","unstructured":"Siewers K, Backer V, Walsted ES (2019) A systematic review of surgical treatment for supraglottic exercise-induced laryngeal obstruction. Laryngoscope Investig Otolaryngol 4(2):227\u2013233","journal-title":"Laryngoscope Investig Otolaryngol"},{"issue":"4","key":"7214_CR21","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1152\/jappl.1976.41.4.508","volume":"41","author":"DE Leith","year":"1976","unstructured":"Leith DE, Bradley M (1976) Ventilatory muscle strength and endurance training. J Appl Physiol 41(4):508\u2013516","journal-title":"J Appl Physiol"},{"issue":"4","key":"7214_CR22","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.jvoice.2013.02.010","volume":"27","author":"A Sandnes","year":"2013","unstructured":"Sandnes A et al (2013) Laryngeal movements during inspiratory muscle training in healthy subjects. J Voice 27(4):448\u2013453","journal-title":"J Voice"},{"issue":"4","key":"7214_CR23","first-page":"1143","volume":"57","author":"TP Brancatisano","year":"1984","unstructured":"Brancatisano TP, Dodd DS, Engel LA (1984) Respiratory activity of posterior cricoarytenoid muscle and vocal cords in humans. J Appl Physiol Respir Environ Exerc Physiol 57(4):1143\u20131149","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"issue":"4","key":"7214_CR24","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.jvoice.2005.03.005","volume":"19","author":"BA Mathers-Schmidt","year":"2005","unstructured":"Mathers-Schmidt BA, Brilla LR (2005) Inspiratory muscle training in exercise-induced paradoxical vocal fold motion. J Voice 19(4):635\u2013644","journal-title":"J Voice"},{"issue":"10","key":"7214_CR25","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1136\/bjsm.2006.033654","volume":"41","author":"J Dickinson","year":"2007","unstructured":"Dickinson J, Whyte G, McConnell A (2007) Inspiratory muscle training: a simple cost-effective treatment for inspiratory stridor. Br J Sports Med 41(10):694\u2013695 (discussion 695)","journal-title":"Br J Sports Med"},{"issue":"8","key":"7214_CR26","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1164\/rccm.201708-1646IM","volume":"197","author":"HSH Clemm","year":"2018","unstructured":"Clemm HSH et al (2018) The heterogeneity of exercise-induced laryngeal obstruction. Am J Respir Crit Care Med 197(8):1068\u20131069","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"7214_CR27","doi-asserted-by":"publisher","DOI":"10.1136\/bmjsem-2018-000436","volume":"5","author":"A Sandnes","year":"2019","unstructured":"Sandnes A, Clemm HH, Hilland M, Volls\u00e6ter M, Heimdal JHH, Eide GE, Halvorsen T, Roksund O (2019) Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training. BMJ Open Sport Exerc Med 5(1):e000436","journal-title":"BMJ Open Sport Exerc Med"},{"key":"7214_CR28","doi-asserted-by":"publisher","unstructured":"Gaylord JN, Peterson S, Ray J (2020) Struggling to breathe: inspiratory muscle training in adolescent athletes. J Voice 14;S0892-1997(20)30172-7. https:\/\/doi.org\/10.1016\/j.jvoice.2020.05.002","DOI":"10.1016\/j.jvoice.2020.05.002"},{"issue":"6","key":"7214_CR29","doi-asserted-by":"publisher","first-page":"1801214","DOI":"10.1183\/13993003.01214-2018","volume":"53","author":"P Laveneziana","year":"2019","unstructured":"Laveneziana P et al (2019) ERS statement on respiratory muscle testing at rest and during exercise. Eur Respir J 53(6):1801214","journal-title":"Eur Respir J"},{"issue":"2","key":"7214_CR30","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1136\/annrheumdis-2014-206186","volume":"74","author":"S Lydersen","year":"2015","unstructured":"Lydersen S (2015) Statistical review: frequently given comments. Ann Rheum Dis 74(2):323\u2013325","journal-title":"Ann Rheum Dis"},{"issue":"9","key":"7214_CR31","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1111\/cea.12550","volume":"45","author":"SJ Fowler","year":"2015","unstructured":"Fowler SJ et al (2015) The VCDQ\u2014a Questionnaire for symptom monitoring in vocal cord dysfunction. Clin Exp Allergy 45(9):1406\u20131411","journal-title":"Clin Exp Allergy"},{"issue":"6","key":"7214_CR32","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1016\/j.jvoice.2013.12.017","volume":"28","author":"JL Gartner-Schmidt","year":"2014","unstructured":"Gartner-Schmidt JL et al (2014) Development and validation of the Dyspnea Index (DI): a severity index for upper airway-related dyspnea. J Voice 28(6):775\u2013782","journal-title":"J Voice"},{"key":"7214_CR33","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.rmed.2019.06.011","volume":"154","author":"H Johansson","year":"2019","unstructured":"Johansson H, Norlander K, Malinovschi A (2019) Increased prevalence of exercise-induced airway symptoms\u2014a five-year follow-up from adolescence to young adulthood. Respir Med 154:76\u201381","journal-title":"Respir Med"},{"issue":"6","key":"7214_CR34","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1016\/S1081-1206(10)61341-5","volume":"96","author":"DR Doshi","year":"2006","unstructured":"Doshi DR, Weinberger MM (2006) Long-term outcome of vocal cord dysfunction. Ann Allergy Asthma Immunol 96(6):794\u2013799","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"10","key":"7214_CR35","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1007\/s00405-011-1656-1","volume":"268","author":"RC Maat","year":"2011","unstructured":"Maat RC et al (2011) Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment. Eur Arch Otorhinolaryngol 268(10):1485\u20131492","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"11","key":"7214_CR36","first-page":"1152","volume":"135","author":"K Norlander","year":"2015","unstructured":"Norlander K et al (2015) Surgical treatment is effective in severe cases of exercise-induced laryngeal obstruction: a follow-up study. Acta Otolaryngol 135(11):1152\u20131159","journal-title":"Acta Otolaryngol"},{"issue":"6","key":"7214_CR37","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1183\/09031936.00038914","volume":"45","author":"RB Banzett","year":"2015","unstructured":"Banzett RB et al (2015) Multidimensional dyspnea profile: an instrument for clinical and laboratory research. Eur Respir J 45(6):1681\u20131691","journal-title":"Eur Respir J"},{"issue":"4","key":"7214_CR38","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1164\/rccm.201111-2042ST","volume":"185","author":"MB Parshall","year":"2012","unstructured":"Parshall MB et al (2012) An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea. Am J Respir Crit Care Med 185(4):435\u2013452","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"7214_CR39","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1136\/bjsports-2011-090190","volume":"45","author":"U Ekelund","year":"2011","unstructured":"Ekelund U, Tomkinson G, Armstrong N (2011) What proportion of youth are physically active? Measurements issues, levels and recent time trends. Br J Sports Med 45(11):859\u2013865","journal-title":"Br J Sports Med"},{"issue":"3","key":"7214_CR40","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/S1081-1206(10)60989-1","volume":"94","author":"M Abu-Hasan","year":"2005","unstructured":"Abu-Hasan M, Tannous B, Weinberger M (2005) Exercise-induced dyspnea in children and adolescents: if not asthma then what? Ann Allergy Asthma Immunol 94(3):366\u2013371","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"7214_CR41","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.jpainsymman.2010.08.016","volume":"41","author":"MJ Hjermstad","year":"2011","unstructured":"Hjermstad MJ et al (2011) Studies comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for assessment of pain intensity in adults: a systematic literature review. J Pain Symptom Manage 41(6):1073\u20131093","journal-title":"J Pain Symptom Manage"},{"issue":"3","key":"7214_CR42","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s00276-008-0307-8","volume":"30","author":"J Wysocki","year":"2008","unstructured":"Wysocki J et al (2008) Measurements of pre- and postpubertal human larynx: a cadaver study. Surg Radiol Anat 30(3):191\u2013199","journal-title":"Surg Radiol Anat"},{"issue":"9","key":"7214_CR43","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1093\/aje\/kwp273","volume":"170","author":"K Corder","year":"2009","unstructured":"Corder K, Ogilvie D, van Sluijs EM (2009) Invited commentary: Physical activity over the life course\u2014whose behavior changes, when, and why? Am J Epidemiol 170(9):1078\u20131081 (discussion 1082\u20131083)","journal-title":"Am J Epidemiol"},{"issue":"3","key":"7214_CR44","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1093\/ije\/dyq272","volume":"40","author":"SC Dumith","year":"2011","unstructured":"Dumith SC et al (2011) Physical activity change during adolescence: a systematic review and a pooled analysis. Int J Epidemiol 40(3):685\u2013698","journal-title":"Int J Epidemiol"},{"issue":"3","key":"7214_CR45","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1159\/000316405","volume":"63","author":"A Nacci","year":"2011","unstructured":"Nacci A et al (2011) Respiratory retraining therapy in long-term treatment of paradoxical vocal fold dysfunction. Folia Phoniatr Logop 63(3):134\u2013141","journal-title":"Folia Phoniatr Logop"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-021-07214-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-021-07214-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-021-07214-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T11:12:53Z","timestamp":1676113973000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-021-07214-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,26]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["7214"],"URL":"https:\/\/doi.org\/10.1007\/s00405-021-07214-5","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,26]]},"assertion":[{"value":"21 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflicts of interest to disclose. Haukeland University Hospital owns parts of US patent No. 11\/134551, protecting the commercial rights of the CLE test.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Regional Ethics Committee (REK number: 2016\/1898), date 24 October 2018. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. All participants provided informed written consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}