{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T13:09:37Z","timestamp":1785762577787,"version":"3.56.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:00:00Z","timestamp":1648166400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:00:00Z","timestamp":1648166400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Turku (UTU) including Turku University Central Hospital"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>This single-group, retrospective, pre-test\u2013post-test study was performed to examine clinical outcomes in treating obstructive sleep apnoea (OSA) with tonsillectomy alone and had the longest follow-up periods to date.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We analysed 151 tonsillectomies in our district between the years 2004 and 2018 that had either sleep apnoea or snoring listed as a diagnosis. Twenty-one patients met our criteria and were included. Patient records were analysed for home sleep apnoea test and Epworth Sleepiness Scale (ESS) scores.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We defined success as a\u2009&gt;\u200950% reduction of the Apnoea\u2013Hypopnea Index (AHI) and a total AHI of\u2009&lt;\u200920 post-surgery. The averages before surgery were an AHI of 22.3 and an ESS of 7.22. The success rate was 47.6% after tonsillectomy as the sole treatment for obstructive sleep apnoea in our adult population. Eleven patients were non-responders. The average ESS score reduction was 0.69 and did not reach statistical significance. With follow-up times ranging from 1.8 to 171\u00a0months, this study had the longest follow-up period compared to other existing studies. No patient with a follow-up longer than one year was a responder.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Our results support that tonsillectomy is an effective treatment for obstructive sleep apnoea in adults with tonsillar hypertrophy. With less severe OSA than those reported on previously, our patients also had less severe daytime sleepiness before surgery, and daytime sleepiness score reductions did not reach statistical significance. In the future, long-term results should be further analysed.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-022-07350-6","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T18:17:50Z","timestamp":1648232270000},"page":"3727-3732","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Treatment of sleep apnoea with tonsillectomy: a retrospective analysis using long-term follow-up data"],"prefix":"10.1007","volume":"279","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6582-7699","authenticated-orcid":false,"given":"Henrik M.","family":"Sj\u00f6blom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Nahkuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miika","family":"Suomela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussi","family":"Jero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaakko M.","family":"Piitulainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,25]]},"reference":[{"issue":"2","key":"7350_CR1","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1513\/pats.200708-119MG","volume":"5","author":"TE Weaver","year":"2008","unstructured":"Weaver TE, Grunstein RR (2008) Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc 5(2):173\u2013178. https:\/\/doi.org\/10.1513\/pats.200708-119MG","journal-title":"Proc Am Thorac Soc"},{"issue":"6","key":"7350_CR2","doi-asserted-by":"publisher","first-page":"780","DOI":"10.5935\/1808-8694.20130139","volume":"79","author":"M Camacho","year":"2013","unstructured":"Camacho M, Certal V, Capasso R (2013) Comprehensive review of surgeries for obstructive sleep apnea syndrome. Braz J Otorhinolaryngol 79(6):780\u2013788. https:\/\/doi.org\/10.5935\/1808-8694.20130139","journal-title":"Braz J Otorhinolaryngol"},{"issue":"10","key":"7350_CR3","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1093\/sleep\/33.10.1408","volume":"33","author":"RN Aurora","year":"2010","unstructured":"Aurora RN, Casey KR, Kristo D, Auerbach S, Bista SR, Chowdhuri S, Karippot A, Lamm C, Ramar K, Zak R, Morgenthaler TI (2010) Practice parameters for the surgical modifications of the upper airway for obstructive sleep apnea in adults. Sleep 33(10):1408\u20131413. https:\/\/doi.org\/10.1093\/sleep\/33.10.1408","journal-title":"Sleep"},{"key":"7350_CR4","doi-asserted-by":"publisher","unstructured":"V\u00e4rendh M, Berg S, Andersson M (2012) Long-term follow-up of patients operated with Uvulopalatopharyngoplasty from 1985 to 1991. Respir Med 106(12):1788\u201393. https:\/\/doi.org\/10.1016\/j.rmed.2012.09.010","DOI":"10.1016\/j.rmed.2012.09.010"},{"issue":"4","key":"7350_CR5","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1111\/jsr.12039","volume":"22","author":"M Gasa","year":"2013","unstructured":"Gasa M, Tamisier R, Launois SH, Sapene M, Martin F, Stach B, Grillet Y, Levy P, Pepin JL (2013) Residual sleepiness in sleep apnea patients treated by continuous positive airway pressure. J Sleep Res 22(4):389. https:\/\/doi.org\/10.1111\/jsr.12039","journal-title":"J Sleep Res"},{"issue":"5","key":"7350_CR6","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1136\/thx.2005.050583","volume":"61","author":"NS Marshall","year":"2006","unstructured":"Marshall NS, Barnes M, Travier N, Campbell AJ, Pierce RJ, Mcevoy RD, Neill AM (2006) Continuous positive airway pressure reduces daytime sleepiness in mild to moderate obstructive sleep apnoea: a meta-analysis. Thorax 61(5):430. https:\/\/doi.org\/10.1136\/thx.2005.050583","journal-title":"Thorax"},{"issue":"3","key":"7350_CR7","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1007\/s11325-019-01864","volume":"23","author":"R Baudouin","year":"2019","unstructured":"Baudouin R, Blumen M, Chaufton C, Chabolle F (2019) Adult sleep apnea and tonsil hypertrophy: should pharyngoplasty be associated with tonsillectomy? Sleep Breath 23(3):917\u2013923. https:\/\/doi.org\/10.1007\/s11325-019-01864","journal-title":"Sleep Breath"},{"key":"7350_CR8","doi-asserted-by":"publisher","unstructured":"Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, Schechter MS, Sheldon SH, Spruyt K, Ward SD, Lehmann C, Shiffman RN, American Academy of Pediatrics (2012) Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics 130(3):576-84. https:\/\/doi.org\/10.1542\/peds.2012-1671","DOI":"10.1542\/peds.2012-1671"},{"issue":"9","key":"7350_CR9","doi-asserted-by":"publisher","first-page":"2176","DOI":"10.1002\/lary.25931","volume":"126","author":"M Camacho","year":"2016","unstructured":"Camacho M, Li D, Kawai M, Zaghi S, Teixeira J, Senchak AJ, Brietzke SE, Frasier S, Certal V (2016) Tonsillectomy for adult obstructive sleep apnea: a systematic review and meta-analysis. Laryngoscope 126(9):2176\u20132186. https:\/\/doi.org\/10.1002\/lary.25931","journal-title":"Laryngoscope"},{"issue":"2","key":"7350_CR10","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1177\/0194599817698671","volume":"157","author":"MM Smith","year":"2017","unstructured":"Smith MM, Peterson E, Yaremchuk KL (2017) The role of tonsillectomy in adults with tonsillar hypertrophy and obstructive sleep apnea. Otolaryngol Head Neck Surg 157(2):331\u2013335. https:\/\/doi.org\/10.1177\/0194599817698671","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"12","key":"7350_CR11","doi-asserted-by":"publisher","first-page":"2859","DOI":"10.1002\/lary.26038","volume":"126","author":"T Holmlund","year":"2016","unstructured":"Holmlund T, Franklin KA, Levring J\u00e4ghagen E, Lindkvist M, Larsson T, Sahlin C, Berggren D (2016) Tonsillectomy in adults with obstructive sleep apnea. Laryngoscope 126(12):2859\u20132862. https:\/\/doi.org\/10.1002\/lary.26038","journal-title":"Laryngoscope"},{"issue":"9","key":"7350_CR12","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1093\/aje\/kws342","volume":"177","author":"PE Peppard","year":"2013","unstructured":"Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM (2013) Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 177(9):1006\u20131014. https:\/\/doi.org\/10.1093\/aje\/kws342","journal-title":"Am J Epidemiol"},{"issue":"9","key":"7350_CR13","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1017\/s0022215100138745","volume":"111","author":"DJ Houghton","year":"1997","unstructured":"Houghton DJ, Camilleri AE, Stone P (1997) Adult obstructive sleep apnoea syndrome and tonsillectomy. J Laryngol Otol 111(9):829\u2013832. https:\/\/doi.org\/10.1017\/s0022215100138745","journal-title":"J Laryngol Otol"},{"issue":"5","key":"7350_CR14","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1177\/0194599815575721","volume":"152","author":"AJ Senchak","year":"2015","unstructured":"Senchak AJ, McKinlay AJ, Acevedo J, Swain B, Tiu MC, Chen BS, Robitschek J, Ruhl DS, Williams LL, Camacho M, Frey WC, O\u2019Connor PD (2015) The effect of tonsillectomy alone in adult obstructive sleep Apnea. Otolaryngol Head Neck Surg 152(5):969\u2013973. https:\/\/doi.org\/10.1177\/0194599815575721","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"1","key":"7350_CR15","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1111\/j.1749-4486.2006.01130.x","volume":"31","author":"S Nakata","year":"2006","unstructured":"Nakata S, Noda A, Yanagi E, Suzuki K, Yamamoto H, Nakashima T (2006) Tonsil size and body mass index are important factors for efficacy of simple tonsillectomy in obstructive sleep apnoea syndrome. Clin Otolaryngol 31(1):41\u201345. https:\/\/doi.org\/10.1111\/j.1749-4486.2006.01130.x","journal-title":"Clin Otolaryngol"},{"issue":"2","key":"7350_CR16","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s11325-013-0875-7","volume":"18","author":"LT Tan","year":"2014","unstructured":"Tan LT, Tan AK, Hsu PP, Loh IC, Yuen HW, Chan YH, Lu PK (2014) Effects of tonsillectomy on sleep study parameters in adult patients with obstructive sleep apnea\u2013a prospective study. Sleep Breath 18(2):265\u2013268. https:\/\/doi.org\/10.1007\/s11325-013-0875-7","journal-title":"Sleep Breath"},{"issue":"6","key":"7350_CR17","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","volume":"14","author":"MW Johns","year":"1991","unstructured":"Johns MW (1991) A new method for measuring daytime sleepiness: the epworth sleepiness scale. Sleep 14(6):540\u2013545. https:\/\/doi.org\/10.1093\/sleep\/14.6.540","journal-title":"Sleep"},{"issue":"4","key":"7350_CR18","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1001\/archotol.127.4.412","volume":"127","author":"G Berger","year":"2001","unstructured":"Berger G, Finkelstein Y, Stein G, Ophir D (2001) Laser-assisted uvulopalatoplasty for snoring: medium- to long-term subjective and objective analysis. Arch Otolaryngol Head Neck Surg 127(4):412\u2013417. https:\/\/doi.org\/10.1001\/archotol.127.4.412","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"9","key":"7350_CR19","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1288\/00005537-199409000-00017","volume":"104","author":"BC Levin","year":"1994","unstructured":"Levin BC, Becker GD (1994) Uvulopalatopharyngoplasty for snoring: Long-term results. Laryngoscope 104(9):1150\u20131152. https:\/\/doi.org\/10.1288\/00005537-199409000-00017","journal-title":"Laryngoscope"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-022-07350-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-022-07350-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-022-07350-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T05:10:56Z","timestamp":1653369056000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-022-07350-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,25]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["7350"],"URL":"https:\/\/doi.org\/10.1007\/s00405-022-07350-6","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,25]]},"assertion":[{"value":"8 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The ethics approval was not applicable by Finnish law and please see attached waiver letter.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}