{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T08:43:11Z","timestamp":1769244191038,"version":"3.49.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1007\/s00405-022-07402-x","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T04:05:57Z","timestamp":1651032357000},"page":"5239-5246","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A comparative study on the clinical profile of COVID-related and non-COVID-related acute invasive fungal rhino sinusitis"],"prefix":"10.1007","volume":"279","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7265-2903","authenticated-orcid":false,"given":"Susan K.","family":"Sebastian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahana","family":"Ponnuvelu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9716-6880","authenticated-orcid":false,"given":"Yukti","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5717-873X","authenticated-orcid":false,"given":"Rakhi Kuari","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"7402_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2021.05.019","author":"AK Singh","year":"2021","unstructured":"Singh AK, Singh R, Joshi SR, Misra A (2021) Mucormycosis in COVID-19: a systematic review of cases reported worldwide and in india. Diabetes Metab Syndr. https:\/\/doi.org\/10.1016\/j.dsx.2021.05.019","journal-title":"Diabetes Metab Syndr"},{"key":"7402_CR2","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1038\/nri3552","volume":"13","author":"RS Hotchkiss","year":"2013","unstructured":"Hotchkiss RS, Monneret G, Payen D (2013) Sepsis-induced immune-suppression: from cellular dysfunctions to immunotherapy. Nat Rev Immunol 13:862\u2013874. https:\/\/doi.org\/10.1038\/nri3552","journal-title":"Nat Rev Immunol"},{"key":"7402_CR3","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3390\/jof5010026","volume":"5","author":"H Prakash","year":"2019","unstructured":"Prakash H, Chakrabarti A (2019) Global epidemiology of mucormycosis. J Fungi 5:26. https:\/\/doi.org\/10.3390\/jof5010026","journal-title":"J Fungi"},{"key":"7402_CR4","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1002\/lary.23912","volume":"123","author":"JH Turner","year":"2013","unstructured":"Turner JH, Soudry E, Nayak JV, Hwang PH (2013) Survival outcomes in acute invasive fungal sinusitis: a systematic review and quantitative synthesis of published evidence. Laryngoscope 123:1112\u20131118","journal-title":"Laryngoscope"},{"key":"7402_CR5","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1002\/lary.23978","volume":"123","author":"MM Monroe","year":"2013","unstructured":"Monroe MM et al (2013) Invasive fungal rhinosinusitis: a 15-year experience with 29 patients. Laryngoscope 123:1583\u20131587","journal-title":"Laryngoscope"},{"key":"7402_CR6","unstructured":"Mucormycosis\u2014WHO World Health Organization. https:\/\/www.who.int>coronavirus-disease-(COVID-19). Accessed 1 Feb 2022"},{"key":"7402_CR7","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1086\/588660","volume":"46","author":"B De Pauw","year":"2008","unstructured":"De Pauw B, Walsh TJ, Donnelly JP et al (2008) Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer\/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC\/MSG) consensus group. Clin Infect Dis 46:1813\u20131821","journal-title":"Clin Infect Dis"},{"key":"7402_CR8","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.4103\/ijo.IJO_1165_21","volume":"69","author":"SG Honavar","year":"2021","unstructured":"Honavar SG (2021) Code Mucor: guidelines for the diagnosis, staging and management of rhino-orbito-cerebral mucormycosis in the setting of COVID-19. Indian J Ophthalmol 69:1361\u20131365. https:\/\/doi.org\/10.4103\/ijo.IJO_1165_21","journal-title":"Indian J Ophthalmol"},{"key":"7402_CR9","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1111\/myc.12278","volume":"58","author":"E Kursun","year":"2015","unstructured":"Kursun E, Turunc T, Demiroglu YZ, Al\u0131\u015fkan HE, Arslan AH (2015) Evaluation of 28 cases of mucormycosis. Mycoses 58:82\u201387","journal-title":"Mycoses"},{"key":"7402_CR10","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.nmni.2014.12.002","volume":"6","author":"F Bellazreg","year":"2015","unstructured":"Bellazreg F, Hattab Z, Meksi S et al (2015) Outcome of mucormycosis after treatment: report of five cases. New Microbes New Infect 6:49\u201352","journal-title":"New Microbes New Infect"},{"key":"7402_CR11","unstructured":"https:\/\/idf.org\/our-network\/regions-members\/south-east-asia\/members\/94-india.html. Accessed 2 Jan 2022"},{"key":"7402_CR12","doi-asserted-by":"publisher","first-page":"2733","DOI":"10.2337\/dbi21-0029","volume":"70","author":"AA Metwally","year":"2021","unstructured":"Metwally AA, Mehta P, Johnson BS, Nagarjuna A, Snyder MP (2021) COVID-19\u2014induced new-onset diabetes: trends and technologies. Diabetes 70:2733\u20132744. https:\/\/doi.org\/10.2337\/dbi21-0029","journal-title":"Diabetes"},{"key":"7402_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.644095","author":"HM Al-kuraishy","year":"2021","unstructured":"Al-kuraishy HM, Al-Gareeb AI, Alblihed M, Cruz-Martins N (2021) COVID-19 in relation to hyperglycemia and diabetes mellitus. Front Cardiovasc Med. https:\/\/doi.org\/10.3389\/fcvm.2021.644095","journal-title":"Front Cardiovasc Med"},{"key":"7402_CR14","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13335","author":"SM Rudramurthy","year":"2021","unstructured":"Rudramurthy SM, Hoenigl M, Meis JF et al (2021) ECMM\/ISHAM recommendations for clinical management of COVID-19 associated mucormycosis in low- and middle-income countries. Mycoses. https:\/\/doi.org\/10.1111\/myc.13335","journal-title":"Mycoses"},{"key":"7402_CR15","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcab190","author":"A Ramaswami","year":"2021","unstructured":"Ramaswami A, Sahu AK, Kumar A, Suresh S (2021) COVID-19-associated mucormycosis presenting to the Emergency Department\u2014an observational study of 70 patients. QJM Int J Med. https:\/\/doi.org\/10.1093\/qjmed\/hcab190","journal-title":"QJM Int J Med"},{"key":"7402_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12070-021-02471-6Accessedon29\/01\/2022","volume":"25","author":"SK Sebastian","year":"2021","unstructured":"Sebastian SK, Kumar VB, Gupta M, Sharma Y (2021) COVID associated invasive fungal sinusitis. Indian J Otolaryngol Head Neck Surg 25:1\u20134. https:\/\/doi.org\/10.1007\/s12070-021-02471-6Accessedon29\/01\/2022","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"issue":"4","key":"7402_CR17","doi-asserted-by":"publisher","first-page":"e241663","DOI":"10.1136\/bcr-2021-241663","volume":"14","author":"MR Shweta","year":"2021","unstructured":"Shweta MR, Supriya PS, Laxminarayana S, Vineeth VK (2021) COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world. BMJ Case Rep 14(4):e241663. https:\/\/doi.org\/10.1136\/bcr-2021-241663","journal-title":"BMJ Case Rep"},{"key":"7402_CR18","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.ajem.2021.02.054","volume":"46","author":"Z Illg","year":"2021","unstructured":"Illg Z, Muller G, Mueller M, Nippert J (2021) Analysis of absolute lymphocyte count in patients with COVID-19. Am J Emerg Med 46:16\u201319. https:\/\/doi.org\/10.1016\/j.ajem.2021.02.054","journal-title":"Am J Emerg Med"},{"key":"7402_CR19","doi-asserted-by":"publisher","first-page":"4281","DOI":"10.1007\/s00405-016-4109-z","volume":"273","author":"M Bakhshaee","year":"2016","unstructured":"Bakhshaee M, Bojdi A, Allahyari A et al (2016) Acute invasive fungal rhinosinusitis: our experience with 18 cases. Eur Arch Otorhinolaryngol 273:4281\u20134287","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"7402_CR20","doi-asserted-by":"publisher","first-page":"103220","DOI":"10.1016\/j.amjoto.2021.103220","volume":"43","author":"R Meher","year":"2022","unstructured":"Meher R, Wadhwa V, Kumar V, Phanbuh DS et al (2022) COVID associated mucormycosis: a preliminary study from a dedicated COVID hospital in Delhi. Am J Otolaryngol 43(1):103220. https:\/\/doi.org\/10.1016\/j.amjoto.2021.103220","journal-title":"Am J Otolaryngol"},{"issue":"7","key":"7402_CR21","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.4103\/ijo.IJO_1565_21","volume":"69","author":"M Sen","year":"2021","unstructured":"Sen M, Honaver SG, Bansal R (2021) Epidemiology, clinical profile, management, and outcome of COVID-19-associated rhino-orbital-cerebral mucormycosis in 2826 patients in India-Collaborative OPAI-IJO Study on Mucormycosis in COVID-19 (COSMIC), report 1. Indian J Ophthalmol 69(7):1670\u20131692","journal-title":"Indian J Ophthalmol"},{"key":"7402_CR22","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.3174\/ajnr.A4298","volume":"36","author":"EH Middlebrooks","year":"2015","unstructured":"Middlebrooks EH, Frost CJ, Jesus ROD, Massini TC, Schmalfuss IM, Mancuso AA (2015) Acute invasive fungal rhinosinusitis: a comprehensive update of CT findings and design of an effective diagnostic imaging model. Am J Neuroradiol 36:1529\u20131535","journal-title":"Am J Neuroradiol"},{"key":"7402_CR23","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1002\/alr.22172","volume":"8","author":"GM Wandell","year":"2018","unstructured":"Wandell GM et al (2018) A multi-institutional review of outcomes in biopsy-proven acute invasive fungal sinusitis. Int Forum Allergy Rhinol 8:1459\u20131468","journal-title":"Int Forum Allergy Rhinol"},{"issue":"1","key":"7402_CR24","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.jmii.2020.09.004","volume":"54","author":"CC Lai","year":"2021","unstructured":"Lai CC, Yu WL (2021) COVID-19 associated with pulmonary aspergillosis: a literature review. J Microbiol Immunol Infect 54(1):46\u201353. https:\/\/doi.org\/10.1016\/j.jmii.2020.09.004","journal-title":"J Microbiol Immunol Infect"},{"key":"7402_CR25","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/s13613-021-00923-4","volume":"11","author":"G Montrucchio","year":"2021","unstructured":"Montrucchio G, Lupia T, Lombardo D et al (2021) Risk factors for invasive aspergillosis in ICU patients with COVID-19: current insights and new key elements. Ann Intensive Care 11:136","journal-title":"Ann Intensive Care"},{"key":"7402_CR26","doi-asserted-by":"publisher","DOI":"10.1002\/lary.2963","author":"NA El-Kholy","year":"2021","unstructured":"El-Kholy NA, Abd El-Fattah AM, Khafagy YW (2021) Invasive fungal sinusitis in post COVID-19 patients a new clinical entity. Laryngoscope. https:\/\/doi.org\/10.1002\/lary.2963","journal-title":"Laryngoscope"},{"key":"7402_CR27","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1001\/jamaoto.2020.0780","volume":"146","author":"B Givi","year":"2020","unstructured":"Givi B, Schiff BA, Chinn SB et al (2020) Safety recommendations for evaluation and surgery of the head and neck during the COVID-19 pandemic. JAMA Otolaryngol Head Neck Surg 146:579\u2013584","journal-title":"JAMA Otolaryngol Head Neck Surg"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-022-07402-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-022-07402-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-022-07402-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T16:07:57Z","timestamp":1664381277000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-022-07402-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,27]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["7402"],"URL":"https:\/\/doi.org\/10.1007\/s00405-022-07402-x","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,27]]},"assertion":[{"value":"4 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Institutional ethics committee clearance obtained. No: SSHEC\/R0192. This study is a retrospective analysis. Hence it does not have a CTRI Number. All procedures performed in this study are in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its amendments. No information revealing the participants identity is included in the manuscript. Informed consent has been waived by the ethics committee in view of the retrospective nature of the study and all the procedures being performed were part of the routine care. All authors declare that all data and materials as well as software application comply with field standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}