{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T19:11:02Z","timestamp":1781291462076,"version":"3.54.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s00405-022-07630-1","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T11:08:56Z","timestamp":1662462536000},"page":"839-845","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Matrix metalloproteinase 7 is associated with clinical and pathological characteristics of salivary adenoid cystic carcinomas"],"prefix":"10.1007","volume":"280","author":[{"given":"Haitao","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7237-5915","authenticated-orcid":false,"given":"Linlin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenliang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,6]]},"reference":[{"issue":"3","key":"7630_CR1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.3892\/mco.2021.2345","volume":"15","author":"T Masui","year":"2021","unstructured":"Masui T, Uemura H, Ota I et al (2021) A study of 24 cases of salivary gland carcinoma with distant metastasis. Mol Clin Oncol 15(3):183","journal-title":"Mol Clin Oncol"},{"issue":"11","key":"7630_CR2","doi-asserted-by":"publisher","first-page":"15384","DOI":"10.18632\/aging.203097","volume":"13","author":"M Zhang","year":"2021","unstructured":"Zhang M, Wu JS, Xian HC et al (2021) CXCR5 induces perineural invasion of salivary adenoid cystic carcinoma by inhibiting microRNA-187. Aging (Albany NY) 13(11):15384\u201315399","journal-title":"Aging (Albany NY)"},{"issue":"1","key":"7630_CR3","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1152\/physrev.1993.73.1.161","volume":"73","author":"P Mignatti","year":"1993","unstructured":"Mignatti P, Rifkin DB (1993) Biology and biochemistry of proteinases in tumor invasion. Physiol Rev 73(1):161\u2013195","journal-title":"Physiol Rev"},{"key":"7630_CR4","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1146\/annurev.cb.09.110193.002545","volume":"9","author":"WG Stetler-Stevenson","year":"1993","unstructured":"Stetler-Stevenson WG, Aznavoorian S, Liotta L (1993) Tumer cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol. 9:541\u2013573","journal-title":"Annu Rev Cell Biol."},{"issue":"1","key":"7630_CR5","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/ijc.20697","volume":"114","author":"FQ Wang","year":"2005","unstructured":"Wang FQ, So J, Reierstad S, Fishman DA (2005) Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase. Int J Cancer 114(1):19\u201331","journal-title":"Int J Cancer"},{"issue":"2","key":"7630_CR6","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.canlet.2005.05.042","volume":"236","author":"F Wang","year":"2006","unstructured":"Wang F, Reierstad S, Fishman DA (2006) Matrilysin over-expression in MCF-7 cells enhances cellular invasiveness and pro-gelatinase activation. Cancer Lett 236(2):292\u2013301","journal-title":"Cancer Lett"},{"issue":"4","key":"7630_CR7","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.1073\/pnas.94.4.1402","volume":"94","author":"CL Wilson","year":"1997","unstructured":"Wilson CL, Heppner KJ, Labosky PA, Hogan BL, Matrisian LM (1997) Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc Natl Acad Sci USA 94(4):1402\u20131407","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"7630_CR8","first-page":"13","volume":"12","author":"DL Hulboy","year":"2004","unstructured":"Hulboy DL, Gautam S, Fingleton B, Matrisian LM (2004) The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse. Oncol Rep 12(1):13\u201317","journal-title":"Oncol Rep"},{"issue":"1","key":"7630_CR9","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0304-3835(01)00772-8","volume":"177","author":"N Huo","year":"2002","unstructured":"Huo N, Ichikawa Y, Shimada H et al (2002) MMP-7 (matrilysin) accelerated growth of human umbilical vein endothelial cells. Cancer Lett 177(1):95\u2013100","journal-title":"Cancer Lett"},{"issue":"9","key":"7630_CR10","first-page":"1856","volume":"55","author":"EC Kohn","year":"1995","unstructured":"Kohn EC, Liotta LA (1995) Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res 55(9):1856\u20131862","journal-title":"Cancer Res"},{"issue":"2","key":"7630_CR11","first-page":"455","volume":"59","author":"CS Melincovici","year":"2018","unstructured":"Melincovici CS, Bo\u015fca AB, \u015eu\u015fman S et al (2018) Vascular endothelial growth factor (VEGF)\u2014key factor in normal and pathological angiogenesis. Rom J Morphol Embryol 59(2):455\u2013467","journal-title":"Rom J Morphol Embryol"},{"issue":"9","key":"7630_CR12","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.17219\/acem\/99527","volume":"28","author":"WH Zhao","year":"2019","unstructured":"Zhao WH, Yuan HY, Ren XY et al (2019) Association between expression of hotair and invasiveness of gliomas, and its predictive value. Adv Clin Exp Med 28(9):1179\u20131183","journal-title":"Adv Clin Exp Med"},{"key":"7630_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2020.153293","volume":"217","author":"H H\u00e4metoja","year":"2021","unstructured":"H\u00e4metoja H, M\u00e4kitie A, B\u00e4ck L et al (2021) Matrix metalloproteinase-7, -8, -9, -15, and -25 in minor salivary gland adenoid cystic carcinoma. Pathol Res Pract 217:153293","journal-title":"Pathol Res Pract"},{"issue":"2","key":"7630_CR14","first-page":"95","volume":"21","author":"N Taghavi","year":"2020","unstructured":"Taghavi N, Yazdani F, Akbarzadeh Baghban A et al (2020) Comparative analysis of P63, maspin and matrix metalloproteinase 2 expression in mucoepidermoid carcinoma and adenoid cystic carcinoma of salivary glands. J Dent (Shiraz) 21(2):95\u2013101","journal-title":"J Dent (Shiraz)"},{"key":"7630_CR15","doi-asserted-by":"publisher","first-page":"9939","DOI":"10.12659\/MSM.918703","volume":"25","author":"B Huang","year":"2019","unstructured":"Huang B, Jin G, Qu C et al (2019) Elevated expression of Notch1 associates with lymph node metastasis of gastric cancer and knock-down of Notch1 attenuates tumor cell progression. Med Sci Monit 25:9939\u20139948","journal-title":"Med Sci Monit"},{"issue":"3","key":"7630_CR16","doi-asserted-by":"publisher","first-page":"2032","DOI":"10.1016\/S0021-9258(17)42131-4","volume":"269","author":"M Gaire","year":"1994","unstructured":"Gaire M, Maghanua Z, McDonnell S et al (1994) Structure and expression of the human gene for the matrix metalloproteinase matrilysin. J Biol Chem 269(3):2032\u20132040","journal-title":"J Biol Chem"},{"issue":"12","key":"7630_CR17","first-page":"1674","volume":"32","author":"W-Q Miao","year":"2009","unstructured":"Miao W-Q, Li H-W, Wang H-J et al (2009) Expression and correlation of MMP-7 and MMP-2 in esophageal cancer in Xinjiang Uygur ethnic group. J Xinjiang Med Univ. 32(12):1674\u20131676","journal-title":"J Xinjiang Med Univ."},{"issue":"11","key":"7630_CR18","first-page":"1349","volume":"39","author":"ZD Hu","year":"2012","unstructured":"Hu ZD, Zhong MZ, Zhou HJ (2012) Expression and significance of MMP-7 and survivin in gastric cancer. Cancer Res. 39(11):1349\u20131352","journal-title":"Cancer Res."},{"issue":"9","key":"7630_CR19","first-page":"662","volume":"30","author":"CY Jiao","year":"2003","unstructured":"Jiao CY, Huang XF, Li JY et al (2003) Expression of matrix proteinase-7 (MMP-7) in gastric cancer. J Clin Oncol 30(9):662\u2013664","journal-title":"J Clin Oncol"},{"issue":"2","key":"7630_CR20","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/s13277-010-0080-2","volume":"32","author":"S Koskensalo","year":"2011","unstructured":"Koskensalo S, Louhimo J, Nordling S et al (2011) MMP-7 as a prognostic marker in colorectal cancer. J Tumour Biol 32(2):259\u2013264","journal-title":"J Tumour Biol"},{"issue":"6","key":"7630_CR21","first-page":"652","volume":"37","author":"KF Kang","year":"2010","unstructured":"Kang KF, Zhang X, Chen XW et al (2010) Expression and significance of MMP-7 and PTEN proteins in primary hepatocellular carcinoma. Cancer Res 37(6):652\u2013655","journal-title":"Cancer Res"},{"issue":"14","key":"7630_CR22","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.3748\/wjg.v11.i14.2117","volume":"11","author":"YJ Li","year":"2005","unstructured":"Li YJ, Wei ZM, Meng YX et al (2005) Beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carci-nogenesis and metastasis. World J Gastroenterol 11(14):2117\u20132123","journal-title":"World J Gastroenterol"},{"issue":"1","key":"7630_CR23","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1677\/ERC-08-0250","volume":"16","author":"R Gallego","year":"2009","unstructured":"Gallego R, Codony-Servat J, Garcia-Albeniz X et al (2009) Serum IGF-I, IGFBP-3, and matrix metalloproteinase-7 levels and acquired chemo-resistance in advanced colorectal cancer. Endocr Relat Cancer 16(1):311\u2013317","journal-title":"Endocr Relat Cancer"},{"issue":"1","key":"7630_CR24","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3109\/02841860903287197","volume":"49","author":"H Luukkaa","year":"2010","unstructured":"Luukkaa H, Klemi P, Hirsim\u00e4ki P et al (2010) Matrix metalloproteinase (MMP)-7 in salivary gland cancer. Acta Oncol 49(1):85\u201390","journal-title":"Acta Oncol"},{"issue":"4","key":"7630_CR25","first-page":"258","volume":"26","author":"DC Li","year":"2010","unstructured":"Li DC, Dong HY, Li DC et al (2010) Expression and significance of HIF-1\u03b1 and MMP-7 in adenoid cystic carcinoma of parotid gland. J Stomatol Res 26(4):258","journal-title":"J Stomatol Res"},{"key":"7630_CR26","first-page":"05","volume":"18","author":"DY Zhang","year":"2011","unstructured":"Zhang DY, Gu YQ, Zhang DY (2011) The role of matrix metalloproteinase-7 in tumor and its mechanism research progress. J Pharm Biotechnol. 18:05","journal-title":"J Pharm Biotechnol."},{"issue":"10","key":"7630_CR27","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1182\/blood-2008-08-172742","volume":"113","author":"T-K Ito","year":"2009","unstructured":"Ito T-K, Ishii G, Ochiai A et al (2009) Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells. Blood 113(10):2363\u20132369","journal-title":"Blood"},{"issue":"17","key":"7630_CR28","doi-asserted-by":"publisher","first-page":"5503","DOI":"10.1158\/1078-0432.CCR-07-4041","volume":"14","author":"Y Yoloyama","year":"2008","unstructured":"Yoloyama Y, Grunebach F, Schmidt SM et al (2008) Mateilysin (MMP-7) is a novel broadly expressed tumor antigen recognized by antigenp-spectific T cells. Clin Cancer Res 14(17):5503\u20135511","journal-title":"Clin Cancer Res"},{"issue":"3","key":"7630_CR29","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1046\/j.1523-1747.2000.00068.x","volume":"115","author":"UB Hormann","year":"2000","unstructured":"Hormann UB, Wasphal R, Van Muijen GN, Ruiter DJ (2000) Matrix metalloproteinases of Matrix metalloproteinases in human melanoma. J Invest Dermatol 115(3):337\u2013344","journal-title":"J Invest Dermatol"},{"issue":"4","key":"7630_CR30","first-page":"765","volume":"57","author":"WG Roberts","year":"1997","unstructured":"Roberts WG, Palade GE (1997) Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res 57(4):765\u2013772","journal-title":"Cancer Res"},{"issue":"51","key":"7630_CR31","doi-asserted-by":"publisher","first-page":"7194","DOI":"10.1038\/sj.onc.1210535","volume":"26","author":"T-K Ito","year":"2007","unstructured":"Ito T-K, Ishii G, Chiba H, Ochiai A (2007) The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells. Oncogene 26(51):7194\u20137203","journal-title":"Oncogene"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-022-07630-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-022-07630-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-022-07630-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T07:06:30Z","timestamp":1674025590000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-022-07630-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,6]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["7630"],"URL":"https:\/\/doi.org\/10.1007\/s00405-022-07630-1","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,6]]},"assertion":[{"value":"25 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All of the authors had no any personal, financial, commercial, or academic conflicts of interest separately.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was conducted in accordance with the Declaration of Helsinki and approved by the ethics committee of First People's Hospital of Jiujiang City.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}