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The study presented in this article aims to assess the effectiveness of an alternative approach by which the injection is performed laterally under ultrasound monitoring.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Study design<\/jats:title>\n                <jats:p>Anatomical dissection study in human cadavers.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Settings<\/jats:title>\n                <jats:p>Academic health care center.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Ultrasound-guided bilateral dye (0.1\u00a0mL of dye solution containing cold-curing polymers, latex, acrylates, acrylic esters, alcohol, and green color) injection in the LCA was performed by means of 24G needles and 1\u00a0mL syringes using the lateral approach. The dye location and distribution were assessed by anatomic dissection, performed immediately after the injection.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In 9\/10 specimens, the dye was exclusively detectable in the LCA. In 1\/10 case (left side), the dye could not be delivered in the LCA because of unintended penetration of the thyroid cartilage by the needle during injection. Anatomic dissection confirmed that the dye spread neither into the thyroarytenoid (TA) nor the cricothyroid muscle (CT).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The anatomic dissection following lateral dye injection in the LCA under ultrasound guide confirmed the precision of this approach in delivery a substance exclusively in a pre-determined target. This feature makes this method an interesting addition or alternative to the standard LEMG-guided BoNT injection at least when the LCA is its target.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Level of evidence<\/jats:title>\n                <jats:p>III.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-023-07843-y","type":"journal-article","created":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T09:50:37Z","timestamp":1676109037000},"page":"2877-2883","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound-guided injection into the lateral crico-arytenoid muscle: a pilot study"],"prefix":"10.1007","volume":"280","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9978-6474","authenticated-orcid":false,"given":"Berit","family":"Schneider-Stickler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guan-Yuh","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Moriggl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,11]]},"reference":[{"key":"7843_CR1","doi-asserted-by":"publisher","first-page":"1110061","DOI":"10.1115\/1.4028428","volume":"136","author":"J Yin","year":"2014","unstructured":"Yin J, Zhang Z (2014) Interaction between the thyroarytenoid and lateral cricoarytenoid muscles in the control of vocal fold adduction and eigenfrequencies. 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