{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:28:00Z","timestamp":1790015280217,"version":"4.0.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>This study is a systematic review of the literature which seeks to evaluate auditory and quality of life (QOL) outcomes of cochlear implantation in patients with Usher syndrome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Systematic review of studies indexed in Medline via PubMed, Ovid EMBASE, Web of Science, CENTRAL and clinicaltrials.gov was performed up to March 9th 2022, conducted in accordance with the PRISMA statement. Patient demographics, comorbidity, details of cochlear implantation, auditory, and QOL outcomes were extracted and summarized.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>33 studies reported over 217 cochlear implants in 187 patients with Usher syndrome, comprising subtypes 1 (56 patients), 2 (9 patients), 3 (23 patients), and not specified (99 patients). Auditory outcomes included improved sound detection, speech perception, and speech intelligibility. QOL outcomes were reported for 75 patients, with benefit reported in the majority.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Many patients with Usher syndrome develop improved auditory outcomes after cochlear implantation with early implantation being an important factor.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-023-08304-2","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T14:02:08Z","timestamp":1699279328000},"page":"1115-1129","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes of cochlear implantation in Usher syndrome: a systematic review"],"prefix":"10.1007","volume":"281","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7647-9503","authenticated-orcid":false,"given":"Hannah Louisa","family":"Cornwall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6037-6558","authenticated-orcid":false,"given":"Chon Meng","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoud","family":"Chaudhry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3065-0269","authenticated-orcid":false,"given":"Jameel","family":"Muzaffar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7343-7105","authenticated-orcid":false,"given":"Peter","family":"Monksfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8050-3617","authenticated-orcid":false,"given":"Manohar L.","family":"Bance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"8304_CR1","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/978-3-319-95046-4_32","volume":"1085","author":"SH Tsang","year":"2018","unstructured":"Tsang SH, Aycinena ARP, Sharma T (2018) Ciliopathy: Usher syndrome. Adv Exp Med Biol 1085:167\u2013170. https:\/\/doi.org\/10.1007\/978-3-319-95046-4_32","journal-title":"Adv Exp Med Biol"},{"key":"8304_CR2","volume-title":"GeneReviews\u00ae","author":"J Lentz","year":"1993","unstructured":"Lentz J, Keats BJB (1993) Usher syndrome type I. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A (eds) GeneReviews\u00ae. University of Washington, Seattle, WA"},{"issue":"5","key":"8304_CR3","first-page":"281","volume":"31","author":"F Forli","year":"2011","unstructured":"Forli F et al (2011) Systematic review of the literature on the clinical effectiveness of the cochlear implant procedure in paediatric patients. Acta Otorhinolaryngol Ital 31(5):281\u2013298","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"8304_CR4","doi-asserted-by":"publisher","DOI":"10.1177\/2515841420952194","author":"M Toms","year":"2020","unstructured":"Toms M, Pagarkar W, Moosajee M (2020) Usher syndrome: clinical features, molecular genetics and advancing therapeutics. Ther Adv Ophthalmol. https:\/\/doi.org\/10.1177\/2515841420952194","journal-title":"Ther Adv Ophthalmol"},{"issue":"2","key":"8304_CR5","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.ijporl.2014.11.002","volume":"79","author":"B Thierry","year":"2015","unstructured":"Thierry B et al (2015) Cochlear implantation and vestibular function in children. Int J Pediatr Otorhinolaryngol 79(2):101\u2013104. https:\/\/doi.org\/10.1016\/j.ijporl.2014.11.002","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"8304_CR6","unstructured":"OCEBM Levels of Evidence Working Group et al (2011) The Oxford levels of evidence 2. Oxford Centre for Evidence-Based Medicine. https:\/\/www.cebm.ox.ac.uk\/resources\/levels-of-evidence\/ocebm-levels-of-evidence. Accessed May 2020."},{"issue":"90","key":"8304_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/hta19900","volume":"19","author":"M Brazzelli","year":"2015","unstructured":"Brazzelli M et al (2015) Collagenase clostridium histolyticum for the treatment of Dupuytren\u2019s contracture: systematic review and economic evaluation. Health Technol Assess 19(90):1\u2013202. https:\/\/doi.org\/10.3310\/hta19900","journal-title":"Health Technol Assess"},{"issue":"4","key":"8304_CR8","first-page":"258","volume":"15","author":"U Derinsu","year":"2002","unstructured":"Derinsu U, Ciprut A (2002) Cochlear implantation in a patient with Usher\u2019s syndrome. Marmara Med J 15(4):258\u2013261","journal-title":"Marmara Med J"},{"issue":"2","key":"8304_CR9","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1179\/146701010X12711475887315","volume":"12","author":"SJ Withers","year":"2011","unstructured":"Withers SJ, Gibson WP, Greenberg SL, Bray M (2011) Comparison of outcomes in a case of bilateral cochlear implantation using devices manufactured by two different implant companies (Cochlear Corporation and Med-El). Cochlear Implants Int 12(2):124\u2013126. https:\/\/doi.org\/10.1179\/146701010X12711475887315","journal-title":"Cochlear Implants Int"},{"issue":"4","key":"8304_CR10","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1179\/1754762812Y.0000000017","volume":"14","author":"S Janeschik","year":"2013","unstructured":"Janeschik S, Teschendorf M, Bagus H, Arweiler-Harbeck D (2013) Influence of etiologic factors on speech perception of cochlear-implanted children. Cochlear Implants Int 14(4):190\u2013199. https:\/\/doi.org\/10.1179\/1754762812Y.0000000017","journal-title":"Cochlear Implants Int"},{"issue":"4","key":"8304_CR11","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1177\/0145482X1611000404","volume":"110","author":"M Wahlqvist","year":"2016","unstructured":"Wahlqvist M, Moller C, Moller K, Danermark B (2016) Implications of deaf blindness: the physical and mental health and social trust of persons with Usher Syndrome Type 3. J Vis Impair Blind 110(4):245\u2013256","journal-title":"J Vis Impair Blind"},{"issue":"2","key":"8304_CR12","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s00405-017-4832-0","volume":"275","author":"F Alzhrani","year":"2018","unstructured":"Alzhrani F, Alhussini R, Hudeib R, Alkaff T, Islam T, Alsanosi A (2018) The outcome of cochlear implantation among children with genetic syndromes. Eur Arch Otorhinolaryngol 275(2):365\u2013369. https:\/\/doi.org\/10.1007\/s00405-017-4832-0","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"9","key":"8304_CR13","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1017\/S0022215115001760","volume":"129","author":"AA Alsanosi","year":"2015","unstructured":"Alsanosi AA (2015) Simultaneous bilateral cochlear implantation in a five-month-old child with Usher syndrome. J Laryngol Otol 129(9):919\u2013922. https:\/\/doi.org\/10.1017\/S0022215115001760","journal-title":"J Laryngol Otol"},{"issue":"5","key":"8304_CR14","doi-asserted-by":"publisher","first-page":"836","DOI":"10.5301\/ejo.5000130","volume":"22","author":"M Serrador-Garc\u00eda","year":"2012","unstructured":"Serrador-Garc\u00eda M, Santos-Bueso E, S\u00e1enz-Franc\u00e9s F, D\u00edaz-Valle D, Mart\u00ednez-De-La-Casa-Borrelia JM, Garc\u00eda-Feij\u00f3o J (2012) Charles Bonnet plus syndrome: apropos of a case. Eur J Ophthalmol 22(5):836\u2013839. https:\/\/doi.org\/10.5301\/ejo.5000130","journal-title":"Eur J Ophthalmol"},{"issue":"3","key":"8304_CR15","doi-asserted-by":"publisher","first-page":"e10","DOI":"10.1097\/MAO.0b013e3182814d15","volume":"34","author":"AP Ruiz","year":"2013","unstructured":"Ruiz AP, Garcia Gomez JM (2013) Labyrinthitis ossificans in a cochlear implant patient with Usher syndrome. Otol Neurotol 34(3):e10\u2013e11. https:\/\/doi.org\/10.1097\/MAO.0b013e3182814d15","journal-title":"Otol Neurotol"},{"issue":"6","key":"8304_CR16","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/j.ijporl.2008.02.013","volume":"72","author":"XZ Liu","year":"2008","unstructured":"Liu XZ et al (2008) Cochlear implantation in individuals with Usher type 1 syndrome. Int J Pediatr Otorhinolaryngol 72(6):841\u2013847. https:\/\/doi.org\/10.1016\/j.ijporl.2008.02.013","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"3","key":"8304_CR17","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1055\/s-0028-1083721","volume":"16","author":"VW Jenison","year":"1995","unstructured":"Jenison VW, Fears BT, Lusk RP (1995) Cochlear implantation of two siblings with Usher syndrome\u2014case studies. Semin Hear 16(3):240\u2013245. https:\/\/doi.org\/10.1055\/s-0028-1083721","journal-title":"Semin Hear"},{"issue":"4 Pt 1","key":"8304_CR18","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1177\/000348949410300405","volume":"103","author":"JB Hinderink","year":"1994","unstructured":"Hinderink JB, Brokx JP, Mens LH, van den Broek P (1994) Results from four cochlear implant patients with Usher\u2019s syndrome. Ann Otol Rhinol Laryngol 103(4 Pt 1):285\u2013293. https:\/\/doi.org\/10.1177\/000348949410300405","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"8304_CR19","first-page":"1885","volume":"18","author":"F Imtiaz","year":"2012","unstructured":"Imtiaz F et al (2012) USH1G with unique retinal findings caused by a novel truncating mutation identified by genome-wide linkage analysis. Mol Vis 18:1885\u20131894","journal-title":"Mol Vis"},{"issue":"6","key":"8304_CR20","doi-asserted-by":"publisher","first-page":"e120","DOI":"10.1097\/MAO.0000000000001441","volume":"38","author":"BP Hartel","year":"2017","unstructured":"Hartel BP et al (2017) Cochlear implantation in patients with Usher Syndrome Type IIa increases performance and quality of life. Otol Neurotol 38(6):e120\u2013e127. https:\/\/doi.org\/10.1097\/MAO.0000000000001441","journal-title":"Otol Neurotol"},{"issue":"1","key":"8304_CR21","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1097\/MAO.0b013e31823dbc56","volume":"33","author":"L Pietola","year":"2012","unstructured":"Pietola L et al (2012) Speech recognition and communication outcomes with cochlear implantation in Usher syndrome type 3. Otol Neurotol 33(1):38\u201341. https:\/\/doi.org\/10.1097\/MAO.0b013e31823dbc56","journal-title":"Otol Neurotol"},{"issue":"2","key":"8304_CR22","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1055\/s-0036-1583306","volume":"21","author":"ACH Hoshino","year":"2017","unstructured":"Hoshino ACH, Echegoyen A, Goffi-Gomez MVS, Tsuji RK, Bento RF (2017) Outcomes of late implantation in Usher syndrome patients. Int Arch Otorhinolaryngol 21(2):140\u2013143. https:\/\/doi.org\/10.1055\/s-0036-1583306","journal-title":"Int Arch Otorhinolaryngol"},{"issue":"8","key":"8304_CR23","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1016\/j.ijporl.2013.05.022","volume":"77","author":"SJ Broomfield","year":"2013","unstructured":"Broomfield SJ, Bruce IA, Henderson L, Ramsden RT, Green KMJ (2013) Cochlear implantation in children with syndromic deafness. Int J Pediatr Otorhinolaryngol 77(8):1312\u20131316. https:\/\/doi.org\/10.1016\/j.ijporl.2013.05.022","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"1","key":"8304_CR24","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1007\/s12070-019-01759-y","volume":"72","author":"G Nair","year":"2020","unstructured":"Nair G, Dham R, Sekhar A, Kumar RS, Kameswaran M (2020) Cochlear implantation in children with Usher\u2019s syndrome: a South Asian experience. Indian J Otolaryngol Head Neck Surg 72(1):140\u2013144. https:\/\/doi.org\/10.1007\/s12070-019-01759-y","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"8304_CR25","doi-asserted-by":"crossref","unstructured":"Vermeulen L, Vandijk J, Hinderink H, Vandenbroek P (1994) Some results of cochlear implants in 4 persons with Ushers syndrome type-I. In: Low vision: research and new developments in rehabilitation, vol 11, pp 419\u2013422","DOI":"10.1080\/09602019408401609"},{"issue":"2","key":"8304_CR26","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1044\/jshr.3502.401","volume":"35","author":"PW Dawson","year":"1992","unstructured":"Dawson PW et al (1992) Cochlear implants in children, adolescents, and prelinguistically deafened adults: speech perception. J Speech Hear Res 35(2):401\u2013417. https:\/\/doi.org\/10.1044\/jshr.3502.401","journal-title":"J Speech Hear Res"},{"issue":"1","key":"8304_CR27","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1097\/00129492-200101000-00010","volume":"22","author":"HK El-Kashlan","year":"2001","unstructured":"El-Kashlan HK, Boerst A, Telian SA (2001) Multichannel cochlear implantation in visually impaired patients. Otol Neurotol 22(1):53\u201356. https:\/\/doi.org\/10.1097\/00129492-200101000-00010","journal-title":"Otol Neurotol"},{"issue":"6","key":"8304_CR28","first-page":"774","volume":"19","author":"SR Saeed","year":"1998","unstructured":"Saeed SR, Ramsden RT, Axon PR (1998) Cochlear implantation in the deaf-blind. Am J Otol 19(6):774\u2013777","journal-title":"Am J Otol"},{"issue":"2","key":"8304_CR29","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1097\/00129492-200303000-00015","volume":"24","author":"N Loundon","year":"2003","unstructured":"Loundon N et al (2003) Usher syndrome and cochlear implantation. Otol Neurotol 24(2):216\u2013221. https:\/\/doi.org\/10.1097\/00129492-200303000-00015","journal-title":"Otol Neurotol"},{"issue":"5","key":"8304_CR30","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1097\/01.mlg.0000205167.08415.9e","volume":"116","author":"RJE Pennings","year":"2006","unstructured":"Pennings RJE, Damen GWJA, Snik AFM, Hoefsloot L, Cremers CWRJ, Mylanus EAM (2006) Audiologic performance and benefit of cochlear implantation in Usher syndrome type I. Laryngoscope 116(5):717\u2013722. https:\/\/doi.org\/10.1097\/01.mlg.0000205167.08415.9e","journal-title":"Laryngoscope"},{"issue":"6","key":"8304_CR31","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/s0196-0709(97)90063-6","volume":"18","author":"Y Shiomi","year":"1997","unstructured":"Shiomi Y, Naito Y, Hirano S, Fujiki N, Honjo I (1997) Cortical activity of a patient with Usher\u2019s syndrome using a cochlear implant. Am J Otolaryngol 18(6):412\u2013414. https:\/\/doi.org\/10.1016\/s0196-0709(97)90063-6","journal-title":"Am J Otolaryngol"},{"issue":"1","key":"8304_CR32","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s10162-020-00742-7","volume":"21","author":"Q Mesnildrey","year":"2020","unstructured":"Mesnildrey Q, Venail F, Carlyon RP, Macherey O (2020) Polarity sensitivity as a potential correlate of neural degeneration in Cochlear implant users. JARO J Assoc Res Otolaryngol 21(1):89\u2013104. https:\/\/doi.org\/10.1007\/s10162-020-00742-7","journal-title":"JARO J Assoc Res Otolaryngol"},{"issue":"5","key":"8304_CR33","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1097\/01.mlg.0000205128.86063.17","volume":"116","author":"GWJA Damen","year":"2006","unstructured":"Damen GWJA, Pennings RJE, Snik AFM, Mylanus EAM (2006) Quality of life and cochlear implantation in Usher syndrome type I. Laryngoscope 116(5):723\u2013728. https:\/\/doi.org\/10.1097\/01.mlg.0000205128.86063.17","journal-title":"Laryngoscope"},{"issue":"7","key":"8304_CR34","doi-asserted-by":"publisher","first-page":"441","DOI":"10.3766\/jaaa.21.7.3","volume":"21","author":"RH Gifford","year":"2010","unstructured":"Gifford RH, Revit LJ (2010) Speech perception for adult cochlear implant recipients in a realistic background noise: effectiveness of preprocessing strategies and external options for improving speech recognition in noise. J Am Acad Audiol 21(7):441\u2013488. https:\/\/doi.org\/10.3766\/jaaa.21.7.3","journal-title":"J Am Acad Audiol"},{"issue":"3","key":"8304_CR35","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1097\/MAO.0b013e3182877ef2","volume":"34","author":"KR Jatana","year":"2013","unstructured":"Jatana KR, Thomas D, Weber L, Mets MB, Silverman JB, Young NM (2013) Usher syndrome: characteristics and outcomes of pediatric cochlear implant recipients. Otol Neurotol 34(3):484\u2013489. https:\/\/doi.org\/10.1097\/MAO.0b013e3182877ef2","journal-title":"Otol Neurotol"},{"issue":"3","key":"8304_CR36","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1177\/0145482X9508900318","volume":"89","author":"PM Chute","year":"1995","unstructured":"Chute PM, Nevins ME (1995) Cochlear implants in people who are deaf-blind. J Vis Impair Blind 89(3):297\u2013301","journal-title":"J Vis Impair Blind"},{"issue":"3","key":"8304_CR37","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/s0196-0709(00)80040-x","volume":"21","author":"SB Waltzman","year":"2000","unstructured":"Waltzman SB, Scalchunes V, Cohen NL (2000) Performance of multiply handicapped children using cochlear implants. Am J Otol 21(3):329\u2013335. https:\/\/doi.org\/10.1016\/s0196-0709(00)80040-x","journal-title":"Am J Otol"},{"issue":"6","key":"8304_CR38","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1016\/j.ijporl.2012.02.059","volume":"76","author":"C Vincent","year":"2012","unstructured":"Vincent C et al (2012) Bilateral cochlear implantation in children: localization and hearing in noise benefits. Int J Pediatr Otorhinolaryngol 76(6):858\u2013864. https:\/\/doi.org\/10.1016\/j.ijporl.2012.02.059","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"6","key":"8304_CR39","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.4210","volume":"9","author":"S Lyutenski","year":"2021","unstructured":"Lyutenski S, Zellhuber N, Helbig R, James P, Bloching M (2021) Cochlear reimplantation from mid-scala to lateral wall electrode array: Surgical and hearing outcome. Clin Case Rep 9(6):e04210. https:\/\/doi.org\/10.1002\/ccr3.4210","journal-title":"Clin Case Rep"},{"issue":"10","key":"8304_CR40","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1016\/j.ijporl.2012.06.020","volume":"76","author":"C Henricson","year":"2012","unstructured":"Henricson C, Wass M, Lidestam B, M\u00f6ller C, Lyxell B (2012) Cognitive skills in children with Usher syndrome type 1 and cochlear implants. Int J Pediatr Otorhinolaryngol 76(10):1449\u20131457. https:\/\/doi.org\/10.1016\/j.ijporl.2012.06.020","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"8304_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10132915","author":"C Davies","year":"2021","unstructured":"Davies C et al (2021) The outcomes of cochlear implantation in Usher syndrome: a systematic review. J Clin Med. https:\/\/doi.org\/10.3390\/jcm10132915","journal-title":"J Clin Med"},{"issue":"9","key":"8304_CR42","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1097\/00005537-200409000-00006","volume":"114","author":"SW Teoh","year":"2004","unstructured":"Teoh SW, Pisoni DB, Miyamoto RT (2004) Cochlear implantation in adults with prelingual deafness. Part I. Clinical results. Laryngoscope 114(9):1536\u20131540. https:\/\/doi.org\/10.1097\/00005537-200409000-00006","journal-title":"Laryngoscope"},{"issue":"44","key":"8304_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/hta13440","volume":"13","author":"M Bond","year":"2009","unstructured":"Bond M et al (2009) The effectiveness and cost-effectiveness of cochlear implants for severe to profound deafness in children and adults: a systematic review and economic model. Health Technol Assess 13(44):1\u2013330. https:\/\/doi.org\/10.3310\/hta13440","journal-title":"Health Technol Assess"},{"issue":"4","key":"8304_CR44","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1097\/01.aud.0000134549.48718.53","volume":"25","author":"UK Cochlear Implant Study Group","year":"2004","unstructured":"UK Cochlear Implant Study Group (2004) Criteria of candidacy for unilateral cochlear implantation in postlingually deafened adults I: theory and measures of effectiveness. Ear Hear 25(4):310\u2013335. https:\/\/doi.org\/10.1097\/01.aud.0000134549.48718.53","journal-title":"Ear Hear"},{"issue":"Suppl 1","key":"8304_CR45","doi-asserted-by":"publisher","first-page":"S193","DOI":"10.1016\/s0165-5876(99)00159-7","volume":"49","author":"M Manrique","year":"1999","unstructured":"Manrique M, Cervera-Paz FJ, Huarte A, Perez N, Molina M, Garc\u00eda-Tapia R (1999) Cerebral auditory plasticity and cochlear implants. Int J Pediatr Otorhinolaryngol 49(Suppl 1):S193\u2013S197. https:\/\/doi.org\/10.1016\/s0165-5876(99)00159-7","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"2","key":"8304_CR46","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0165-5876(97)00058-X","volume":"41","author":"AFM Snik","year":"1997","unstructured":"Snik AFM, Makhdoum MJA, Vermeulen AM, Brokx JPL, van den Broeka P (1997) The relation between age at the time of cochlear implantation and long-term speech perception abilities in congenitally deaf subjects. Int J Pediatr Otorhinolaryngol 41(2):121\u2013131. https:\/\/doi.org\/10.1016\/S0165-5876(97)00058-X","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"6","key":"8304_CR47","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/j.ijporl.2015.03.014","volume":"79","author":"M Langereis","year":"2015","unstructured":"Langereis M, Vermeulen A (2015) School performance and wellbeing of children with CI in different communicative-educational environments. Int J Pediatr Otorhinolaryngol 79(6):834\u2013839. https:\/\/doi.org\/10.1016\/j.ijporl.2015.03.014","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"7","key":"8304_CR48","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1001\/jama.284.7.850","volume":"284","author":"AK Cheng","year":"2000","unstructured":"Cheng AK, Rubin HR, Powe NR, Mellon NK, Francis HW, Niparko JK (2000) Cost-utility analysis of the cochlear implant in children. JAMA 284(7):850\u2013856. https:\/\/doi.org\/10.1001\/jama.284.7.850","journal-title":"JAMA"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-023-08304-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-023-08304-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-023-08304-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T09:06:18Z","timestamp":1707469578000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-023-08304-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,6]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["8304"],"URL":"https:\/\/doi.org\/10.1007\/s00405-023-08304-2","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,6]]},"assertion":[{"value":"6 May 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 November 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}